Antiinflammatory effect of the ethanol extract of berberis koreana in a gerbil model of cerebral ischemia/reperfusion

Phytotherapy Research

Volumn 22, Issue 11, 2008, Pages 1527-1532

  Yoo, Ki Yeon ^a   Hwang, In Koo ^b   Kim, Jong Dai ^c   Kang, Il Jun ^a   Park, Jinseu ^a   Yi, Jae Seon ^c   Kim, Jin Kyu ^c   Bae, Young Soo ^c   Won, Moo Ho ^a  

^a Hallym University   (South Korea)

^b Seoul National University   (South Korea)

^c Kangwon National University   (South Korea)

Author keywords

Antiinflammation; Berberry extract; Cyclooxygenase 2; Hippocampal CA1 pyramidal cells; Prostaglandin E2; Transient ischemia

Indexed keywords

ALCOHOL; BERBERINE; BERBERIS KOREANA EXTRACT; CYCLOOXYGENASE 2; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; PLANT EXTRACT; PROSTAGLANDIN E2; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BERBERIS; BERBERIS KOREANA; BRAIN ISCHEMIA; BRAIN LEVEL; CELL STRAIN; CEREBROVASCULAR ACCIDENT; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; DRUG POTENCY; EXPERIMENTAL MODEL; GERBIL; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; MALE; NEUROPROTECTION; NONHUMAN; PROSTAGLANDIN SYNTHESIS; PROTEIN EXPRESSION; PYRAMIDAL NERVE CELL; QUANTITATIVE ASSAY; RAT; REPERFUSION INJURY;

ANIMALS; ANTI-INFLAMMATORY AGENTS; BERBERINE; BERBERIS; CYCLOOXYGENASE 2; DINOPROSTONE; DISEASE MODELS, ANIMAL; GERBILLINAE; ISCHEMIC ATTACK, TRANSIENT; MALE; NEUROPROTECTIVE AGENTS; PC12 CELLS; PLANT EXTRACTS; PYRAMIDAL CELLS; RATS; REPERFUSION INJURY;

ANIMALIA; BERBERIS KOREANA; GERBILLINAE;

EID: 57349172220     PISSN: 0951418X     EISSN: 10991573     Source Type: Journal    
DOI: 10.1002/ptr.2527     Document Type: Article

References (28)

1. Barone FC, Feuerstein GZ. 1999. Inflammatory mediators and stroke: new opportunities for novel therapeutics. J Cereb Blood Flow Metab 19: 819-834.
2. Bezzi P, Carmignoto G, Pasti L et al. 1998. Prostaglandins stimulate calcium-dependent glutamate release in astrocytes. Nature 391: 281-285.
3. Breder CD, Dewitt D, Kraig RP. 1995. Characterization of inducible cyclooxygenase in rat brain. J Comp Neurol 355: 296-315.
4. Brezová V, Dvoranová D, Košt'álová D. 2004. Oxygen activation by photoexcited protoberberinium alkaloids from Mahonia aquifolium. Phytother Res 18: 640-646.
5. Candelario-Jalil E, González-Falcón A, García- Cabrera M et al. 2003. Assessment of the relative contribution of COX-1 and COX-2 isoforms to ischemia-induced oxidative damage and neurodegeneration following transient global cerebral ischemia. J Neurochem 86: 545-555.
6. Cao C, Matsumura K, Yamagata K, Watanabe Y. 1995. Induction by lipopolysaccharide of cyclooxygenase-2 mRNA in rat brain; its possible role in the febrile response. Brain Res 697: 187-196.
7. Colangelo V, Gordon WC, Mukherjee PK, Trivedi P, Ottino P. 2004. Downregulation of COX-2 and JNK expression after induction of ischemic tolerance in the gerbil brain. Brain Res 1016: 195-200.
8. Dore S, Otsuka T, Mito T et al. 2003. Neuronal overexpression of cyclooxygenase-2 increases cerebral infarction. Ann Neurol 54: 155-162.
9. Graham SH, Hickey RW. 2003. Cyclooxygenases in central nervous system diseases: a special role for cyclooxygenase 2 in neuronal cell death. Arch Neurol 60: 628-630.
10. 6 active form) and its neuroprotection in experimental ischemic damage. Exp Neurol 206: 114-125.
11. Ikram N. 1975. A review on the chemical and pharmacological aspects of genus Berberis. Planta Med 28: 353-358.
12. Ivanovska N, Philipov S. 1996. Study on the anti-inflammatory action of Berberis vulgaris root extract, alkaloid fractions and pure alkaloids. Int J Immunopharmacol 18: 553-561.
13. Jantan I, Raweh SM, Yasin YHM, Murad S. 2006. Antiplatelet activity of aporphine and phenanthrenoid alkaloids from Aromadendron elegans Blume. Phytother Res 20: 493-496.
14. 2 levels in several brain areas as determined by microdialysis. Am J Physiol 262: E246-E251.
15. Küpeli E, Koşar M, Yeşilada E, Başer KHC, Başer C. 2002. A comparative study on the anti-inflammatory, antinociceptive and antipyretic effects of isoquinoline alkaloids from the roots of Turkish Berberis species. Life Sci 72: 645-657.
16. 2 production. Phytother Res 19: 103-106.
17. Liang X, Wu L, Wang Q et al. 2007. Function of COX-2 and prostaglandins in neurological disease. J Mol Neurosci 33: 94-99.
18. Nakayama M, Uchimura K, Zhu RL et al. 1998. Cyclooxygenase-2 inhibition prevents delayed death of CA1 neurons following global ischemia. Proc Natl Acad Sci USA 95: 10954-10959.
19. Nogawa S, Zhang F, Ross ME, ladecola C. 1997. Cyclo-oxygenase-2 gene expression in neurons contributes to ischemic brain damage. J Neurosci 17: 2746-2755.
20. Ochiai T, Shimeno H, Mishima K et al. 2007. Protective effects of carotenoids from saffron on neuronal injury in vitro and in vivo. Biochim Biophys Acta 1770: 578-584.
21. Pasinetti GM, Aisen PS. 1998. Cyclooxygenase-2 expression is increased in frontal cortex of Alzheimer's disease brain. Neuroscience 87: 319-324.
22. Planas AM, Soriano MA, Rodríguez-Farré E, Ferrer I. 1995. Induction of cyclooxygenase-2 mRNA and protein following transient focal ischemia in the rat brain. Neurosci Lett 200: 187-190.
23. 2 stimulates glutamate receptor-dependent astrocyte neuromodulation in cultured hippocampal cells. J Neurobiol 41: 221-229.
24. Slobodníková L, Košt'álová D, Labudová D, Kotulová D, Kettmann V. 2004. Antimicrobial activity of Mahonia aquifolium crude extract and its major isolated alkaloids. Phytother Res 18: 674-476.
25. Tanaka T, Metori K, Mineo S, Hirotani M, Furuya T, Kobayashi S. 1993. Inhibitory effects of berberine-type alkaloids on elastase. Planta Med. 59: 200-202.
26. Wei YZ, Yao ZB, Yuan QF, Chen YC. 1995. Protective effects of berberine on rat hippocampus against cerebral ischemia. Chin J Chem Neuroanat 11: 315-321.
27. Yamagata K, Andreasson KI, Kaufmann WE, Barnes CA, Worley PF. 1993. Expression of a mitogen-inducible cyclooxygenase in brain neurons: regulation by synaptic activity and glucocorticoids. Neuron 11: 371-386.
28. Yoo KY, Hwang IK, Lim BO et al. 2006. Berberry extract reduces neuronal damage and N-methyl-D-aspartate receptor 1 immunoreactivity in the gerbil hippocampus after transient forebrain ischemia. Biol Pharm Bull 29: 623-628.