Berberine and a Berberis lycium extract inactivate Cdc25A and induce α-tubulin acetylation that correlate with HL-60 cell cycle inhibition and apoptosis

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis

Volumn 683, Issue 1-2, 2010, Pages 123-130

  Khan, Musa ^a,b,c   Giessrigl, Benedikt ^b   Vonach, Caroline ^b   Madlener, Sibylle ^b   Prinz, Sonja ^c   Herbaceck, Irene ^d   Hölzl, Christine ^d   Bauer, Sabine ^b   Viola, Katharina ^b   Mikulits, Wolfgang ^d   Quereshi, Rizwana Aleem ^a   Knasmüller, Siegfried ^d   Grusch, Michael ^d   Kopp, Brigitte ^c   Krupitza, Georg ^b  

^a QUAID I AZAM UNIVERSITY   (Pakistan)

^b MEDICAL UNIVERSITY OF VIENNA   (Austria)

^c UNIVERSITY OF VIENNA   (Austria)

^d MEDICAL UNIVERSITY OF VIENNA   (Austria)

Author keywords

Berberis lycium; Cancer; Ethnopharmacology; Polar extract

Indexed keywords

ACETIC ACID ETHYL ESTER; ALPHA TUBULIN; BERBERINE; BERBERIS LYCIUM EXTRACT; BUTANOL; CHECKPOINT KINASE 2; CYCLIN D1; CYCLIN DEPENDENT KINASE 1; HERBACEOUS AGENT; PALMATINE; PROTEIN P53; PROTEIN TYROSINE PHOSPHATASE; UNCLASSIFIED DRUG;

ACETYLATION; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; BERBERIS; BERBERIS LYCIUM; CANCER INHIBITION; CELL CYCLE ARREST; CELL CYCLE S PHASE; CELL PROLIFERATION; CELL STRAIN HL 60; CONTROLLED STUDY; DRUG DETERMINATION; DRUG POTENCY; ENZYME ACTIVATION; ENZYME DEGRADATION; ENZYME INACTIVATION; ENZYME PHOSPHORYLATION; GENE EXPRESSION REGULATION; GENOTOXICITY; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROMYELOCYTIC LEUKEMIA; SOLVENT EXTRACTION;

ACETYLATION; APOPTOSIS; BERBERINE; BERBERIS; BLOTTING, WESTERN; CDC25 PHOSPHATASES; CELL CYCLE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CHROMATOGRAPHY, THIN LAYER; COMET ASSAY; HL-60 CELLS; HUMANS; PHOSPHORYLATION; PLANT EXTRACTS; PLANT ROOTS; TUBULIN;

BERBERIS LYCIUM;

EID: 71549126801     PISSN: 00275107     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mrfmmm.2009.11.001     Document Type: Article

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