Therapeutic targeting of the epidermal growth factor receptor in human cancer

Critical Reviews in Oncogenesis

Volumn 17, Issue 1, 2012, Pages 31-50

  Dhomen, Nathalie S ^a   Mariadason, John ^a   Tebbutt, Niall ^a   Scott, Andrew M ^a  

^a OLIVIA NEWTON JOHN CANCER RESEARCH INSTITUTE   (Australia)

Author keywords

Combination therapy; Drug resistance; Drug targeting; EGFR; Receptor structure; Receptor trafficking; Signal transduction

Indexed keywords

ABT 806; AFATINIB; CANERTINIB; CAPECITABINE; CETUXIMAB; DACOMITINIB; EPIDERMAL GROWTH FACTOR RECEPTOR; ERLOTINIB; FLUOROPYRIMIDINE; GEFITINIB; GEMCITABINE; IRINOTECAN; LAPATINIB; LETROZOLE; MATUZUMAB; MDX 447; MONOCLONAL ANTIBODY; NECITUMUMAB; NERATINIB; NIMOTUZUMAB; OXALIPLATIN; PANITUMUMAB; PELITINIB; UNCLASSIFIED DRUG; ZALUTUMUMAB; ANTINEOPLASTIC AGENT; PROTEIN KINASE INHIBITOR;

ANTINEOPLASTIC ACTIVITY; ARTICLE; BREAST CANCER; CANCER RESISTANCE; CANCER THERAPY; CLINICAL TRIAL; COLORECTAL CANCER; DRUG TARGETING; GENE MUTATION; GLIOBLASTOMA; HEAD AND NECK CANCER; HUMAN; LUNG NON SMALL CELL CANCER; NASOPHARYNX CANCER; PANCREAS CANCER; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN STRUCTURE; SQUAMOUS CELL CARCINOMA; BIOLOGICAL MODEL; DRUG ANTAGONISM; DRUG EFFECT; DRUG RESISTANCE; GENETICS; IMMUNOLOGY; METABOLISM; METHODOLOGY; MOLECULARLY TARGETED THERAPY; MUTATION; NEOPLASM; PHYSIOLOGY; REVIEW;

ANTIBODIES, MONOCLONAL; ANTINEOPLASTIC AGENTS; DRUG RESISTANCE, NEOPLASM; HUMANS; MODELS, BIOLOGICAL; MOLECULAR TARGETED THERAPY; MUTATION; NEOPLASMS; PROTEIN KINASE INHIBITORS; RECEPTOR, EPIDERMAL GROWTH FACTOR;

EID: 84861495556     PISSN: 08939675     EISSN: 21626448     Source Type: Journal    
DOI: 10.1615/CritRevOncog.v17.i1.40     Document Type: Article

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