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Volumn 27, Issue 2, 2005, Pages 317-325

Coexpression, prognostic significance and predictive value of EGFR, EGFRvIII and phosphorylated EGFR in colorectal cancer

Author keywords

Colorectal; EGFR; EGFRvIII; PEGFR; Prognosis; Radio therapy

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR; EPIDERMAL GROWTH FACTOR RECEPTOR VIII;

EID: 33644677317     PISSN: 10196439     EISSN: 17912423     Source Type: Journal    
DOI: 10.3892/ijo.27.2.317     Document Type: Article
Times cited : (62)

References (50)
  • 1
    • 0036223999 scopus 로고    scopus 로고
    • Prognosis and response to therapy in colorectal cancer
    • 2(X)2
    • Walker J and Quirkc P: Prognosis and response to therapy in colorectal cancer. Eur J Cancer 38: 880-886. 2(X)2.
    • Eur J Cancer , vol.38 , pp. 880-886
    • Walker, J.1    Quirkc, P.2
  • 3
    • 0001874124 scopus 로고
    • Epidermal growth factor and its receptor in human cancer
    • Sluyser M red. Ellis Horwood Ltd. Chichester
    • Harris AL and Neal DE: Epidermal growth factor and its receptor in human cancer. In: Growth Factors and Oncogenes in Breast Cancer. Sluyser M red). Ellis Horwood Ltd.. Chichester. pp60-90. 1987.
    • (1987) Growth Factors and Oncogenes in Breast Cancer , pp. 60-90
    • Harris, A.L.1    Neal, D.E.2
  • 4
    • 0026028343 scopus 로고
    • Prevalence of aberrant expression of the epidermal growth factor receptor in human cancers
    • Gullick WG: Prevalence of aberrant expression of the epidermal growth factor receptor in human cancers. Br Med Bull 47: 87-98. 1991.
    • (1991) Br Med Bull , vol.47 , pp. 87-98
    • Gullick, W.G.1
  • 5
    • 0028008469 scopus 로고
    • The receptor for EGF and its ligands: Expression, prognostic value and target for therapy in cancer
    • Modjtahedi H and Dean C: The receptor for EGF and its ligands: expression, prognostic value and target for therapy in cancer. Int J Oncol 4: 277-296. 1994.
    • (1994) Int J Oncol , vol.4 , pp. 277-296
    • Modjtahedi, H.1    Dean, C.2
  • 6
    • 0028955388 scopus 로고
    • Epidermal growth factor-related peptides and their receptors in human malignancies
    • Salomon DS. Bradt R. Ciardiello F and Normano N: Epidermal growth factor-related peptides and their receptors in human malignancies. Crit Rev Oncol Hematol 19: 183-232. 1995.
    • (1995) Crit Rev Oncol Hematol , vol.19 , pp. 183-232
    • Salomon, D.S.1    Bradt, R.2    Ciardiello, F.3    Normano, N.4
  • 7
    • 0034778447 scopus 로고    scopus 로고
    • Gee JMW and Harper ME; EGFR and cancer prognosis
    • Nicholson RI. Gee JMW and Harper ME; EGFR and cancer prognosis. Eur J Cancer 37: 9-15. 2001.
    • (2001) Eur J Cancer , vol.37 , pp. 9-15
    • Nicholson, R.I.1
  • 8
    • 2342492317 scopus 로고    scopus 로고
    • Review of epidermal growth factor receptor biology
    • Herbst RS: Review of epidermal growth factor receptor biology. Int J Radial Oncol Biol Phys 59: 21-26. 2004.
    • (2004) Int J Radial Oncol Biol Phys , vol.59 , pp. 21-26
    • Herbst, R.S.1
  • 9
    • 0041629450 scopus 로고    scopus 로고
    • Status of epidermal growth factor receptor antagonists in the biology and treatment of cancer
    • 2(X)3
    • Mendelsohn J and Baselga J: Status of epidermal growth factor receptor antagonists in the biology and treatment of cancer. J Clin Oncol 21: 2787-2799. 2(X)3.
    • J Clin Oncol , vol.21 , pp. 2787-2799
    • Mendelsohn, J.1    Baselga, J.2
  • 10
    • 1242293093 scopus 로고    scopus 로고
    • Rationale and clinical basis for combining gefitinib (IRESSA ZD 1839) with radiation therapy for solid tumours
    • Ochs JS: Rationale and clinical basis for combining gefitinib (IRESSA ZD 1839) with radiation therapy for solid tumours. Int J Radial Oncol Biol Phys 58: 941-949. 2004.
    • (2004) Int J Radial Oncol Biol Phys , vol.58 , pp. 941-949
    • Ochs, J.S.1
  • 11
    • 0024312421 scopus 로고
    • Receptors for epidermal growth factor and sex steroid hormones in human colorectal carcinomas
    • Magnusson I. Rosen AV. Nilsson R. Macias A. Perez R and Skoog L: Receptors for epidermal growth factor and sex steroid hormones in human colorectal carcinomas. Anticancer Res 9: 299-302. 1989.
    • (1989) Anticancer Res , vol.9 , pp. 299-302
    • Magnusson, I.1    Rosen, A.V.2    Nilsson, R.3    MacIas, A.4    Perez, R.5    Skoog, L.6
  • 12
    • 0025606461 scopus 로고
    • Epidermal growth factor receptor expression in colorectal cancer
    • Steele RJ. Kelly P. Ellul B and Eremin O: Epidermal growth factor receptor expression in colorectal cancer. Br J Surg 77: 1352-1354. 1990.
    • (1990) Br J Surg , vol.77 , pp. 1352-1354
    • Steele, R.J.1    Kelly, P.2    Ellul, B.3    Eremin, O.4
  • 14
    • 0027415146 scopus 로고
    • The prognostic significance of proliferating cell nuclear antigen, epidermal growth factor receptor and mdr gene expression in colorectal cancers
    • Mayer A. Takimoto M. Fritz E. Schllander G. Kofler K and Ludwig H: The prognostic significance of proliferating cell nuclear antigen, epidermal growth factor receptor and mdr gene expression in colorectal cancers. Cancer 71: 2454-2460. 1993.
    • (1993) Cancer , vol.71 , pp. 2454-2460
    • Mayer, A.1    Takimoto, M.2    Fritz, E.3    Schllander, G.4    Kofler, K.5    Ludwig, H.6
  • 15
    • 0028343950 scopus 로고
    • Expression of EGF. EGF-receptor. P53, v-erb B and ras p21 in colorectal neoplasms by immuno-staining paraffin-embedded tissues
    • Hayashi Y. Widjono YW. Ohta K. Hanioka K. Obayashi C. Itoh K. Imai Y and Itoh H: Expression of EGF. EGF-receptor. p53, v-erb B and ras p21 in colorectal neoplasms by immuno-staining paraffin-embedded tissues. Pathol Int 44: 124-130. 1994.
    • (1994) Pathol Int , vol.44 , pp. 124-130
    • Hayashi, Y.1    Widjono, Y.W.2    Ohta, K.3    Hanioka, K.4    Obayashi, C.5    Itoh, K.6    Imai, Y.7    Itoh, H.8
  • 16
    • 0035447953 scopus 로고    scopus 로고
    • Epidermal growth factor receptor immunohistochemical reactivity in patients with American Joint Committee on Cancer Stage IV colon adenocarcinoma: Implications for a standardized scoring system
    • Goldstein NS and Armin M: Epidermal growth factor receptor immunohistochemical reactivity in patients with American Joint Committee on Cancer Stage IV colon adenocarcinoma: implications for a standardized scoring system. Cancer 92: 1331-1346. 2001.
    • (2001) Cancer , vol.92 , pp. 1331-1346
    • Goldstein, N.S.1    Armin, M.2
  • 18
    • 0037441914 scopus 로고    scopus 로고
    • Eberly S and Sahasrabudhe DM; Vascular endothelial growth factor, CD86 and epidermal growth factor receptor expression and survival in patients with stage II and stage III colon carcinoma
    • Khorana AA. Rayan CK. Cox C. Eberly S and Sahasrabudhe DM; Vascular endothelial growth factor. CD86. and epidermal growth factor receptor expression and survival in patients with stage II and stage III colon carcinoma. Cancer 97: 960-968, 2003.
    • (2003) Cancer , vol.97 , pp. 960-968
    • Khorana, A.A.1    Rayan, C.K.2    Cox, C.3
  • 19
    • 0142011609 scopus 로고    scopus 로고
    • Reduced survival of rectal cancer patients with increased tumour epidermal growth factor receptor levels
    • Kopp R. Rothbauer E, Mueller E. Schildberg FW, Jauch KW and Pfeiffer A: Reduced survival of rectal cancer patients with increased tumour epidermal growth factor receptor levels. Dis Colon Rectum 6: 1391-1399, 2003.
    • (2003) Dis Colon Rectum , vol.6 , pp. 1391-1399
    • Kopp, R.1    Rothbauer, E.2    Mueller, E.3    Schildberg, F.W.4    Jauch, K.W.5    Pfeiffer, A.6
  • 20
    • 19944426509 scopus 로고    scopus 로고
    • Impact of EGFR expression on colorectal cancer patient prognosis and survival
    • Spano J-P, Lagorce C, Allan D, et al: Impact of EGFR expression on colorectal cancer patient prognosis and survival. Ann Oncol 16: 102-108.2005.
    • (2005) Ann Oncol , vol.16 , pp. 102-108
    • Spano, J.-P.1    Lagorce, C.2    Allan, D.3
  • 21
    • 0038461104 scopus 로고    scopus 로고
    • Epidermal growth factor receptor (EGFR) as a target in cancer therapy: Understanding the role of receptor expression and other molecular determinants that could influence the response to anti-EGFR drugs
    • Ciardiello F and Tortora G: Epidermal growth factor receptor (EGFR) as a target in cancer therapy: understanding the role of receptor expression and other molecular determinants that could influence the response to anti-EGFR drugs. Eur J Cancer 3: 1348-1354. 2003.
    • (2003) Eur J Cancer , vol.3 , pp. 1348-1354
    • Ciardiello, F.1    Tortora, G.2
  • 22
    • 3042785708 scopus 로고    scopus 로고
    • Immunohistochemical detection of EGFR in paraffin-embedded tumour tissues: Variation due to choice of fixative and storage time of tissue sections
    • Atkins D. Reiffen KA., Tegtmeier CL, Winther H. Bonato MS and Storkel S: Immunohistochemical detection of EGFR in paraffin-embedded tumour tissues: variation due to choice of fixative and storage time of tissue sections. J Histochem Cytochem 52: 893-901.2004.
    • (2004) J Histochem Cytochem , vol.52 , pp. 893-901
    • Atkins, D.1    Reiffen, K.A.2    Tegtmeier, C.L.3    Winther, H.4    Bonato, M.S.5    Storkel, S.6
  • 24
    • 0034954124 scopus 로고    scopus 로고
    • The type III epidermal growth factor receptor mutation. Biological significance and potential target for anti-cancer therapy
    • Pedersen MW, Meltorn M. Damstrup L and Poulsen HS: The type III epidermal growth factor receptor mutation. Biological significance and potential target for anti-cancer therapy. Ann Oncol 12:745-760, 2001.
    • (2001) Ann Oncol , vol.12 , pp. 745-760
    • Pedersen, M.W.1    Meltorn, M.2    Damstrup, L.3    Poulsen, H.S.4
  • 25
    • 2342624080 scopus 로고    scopus 로고
    • EGFR mutations in lung cancer: Correlation with clinical response to gefitinib therapy
    • Paez JG. Janne PA. Lee JC, et al: EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy. Science 304: 1497-1500. 2004.
    • (2004) Science , vol.304 , pp. 1497-1500
    • Paez, J.G.1    Janne, P.A.2    Lee, J.C.3
  • 27
    • 0028800035 scopus 로고
    • Frequent expression of a mutant epidermal growth factor receptor in multiple human tumours
    • Moscatello DK. Holgado-Madruga M, Godwin AK, et al: Frequent expression of a mutant epidermal growth factor receptor in multiple human tumours. Cancer Res 55: 5536-5539, 1995.
    • (1995) Cancer Res , vol.55 , pp. 5536-5539
    • Moscatello, D.K.1    Holgado-Madruga, M.2    Godwin, A.K.3
  • 29
    • 0027457670 scopus 로고
    • The human EGF receptor as a target for cancer therapy: Six new rat mAbs against the receptor on the breast carcinoma MDA-MB 468
    • Modjtahcdi H, Styles JM and Dean CJ: The human EGF receptor as a target for cancer therapy: six new rat mAbs against the receptor on the breast carcinoma MDA-MB 468. Br J Cancer 67: 247-253, 1993.
    • (1993) Br J Cancer , vol.67 , pp. 247-253
    • Modjtahcdi, H.1    Styles, J.M.2    Dean, C.J.3
  • 30
    • 4043078573 scopus 로고    scopus 로고
    • The expression and prognostic significance of HER-2 in colorectal cancer and its relationship with clinicopathological parameters
    • Essapen S. Thomas H. Green M. De Vries C. Cook MG. Marks C, Topham C and Modjtahedi H: The expression and prognostic significance of HER-2 in colorectal cancer and its relationship with clinicopathological parameters. Int J Oncol 24: 241-248, 2004.
    • (2004) Int J Oncol , vol.24 , pp. 241-248
    • Essapen, S.1    Thomas, H.2    Green, M.3    De Vries, C.4    Cook, M.G.5    Marks, C.6    Topham, C.7    Modjtahedi, H.8
  • 31
    • 0242684480 scopus 로고    scopus 로고
    • Targeting of cells expressing wild-type EGFR and type-ill mutant EGFR (EGFRvlII) by anti-EGFR mAb ICR62: A two-pronged attack for tumour therapy
    • Modjtahedi H. Moscatello DK. Box G, et al: Targeting of cells expressing wild-type EGFR and type-ill mutant EGFR (EGFRvlII) by anti-EGFR mAb ICR62: a two-pronged attack for tumour therapy. Int J Cancer 105: 273-280, 2003.
    • (2003) Int J Cancer , vol.105 , pp. 273-280
    • Modjtahedi, H.1    Moscatello, D.K.2    Box, G.3
  • 32
    • 4143081729 scopus 로고    scopus 로고
    • Serum EGF-receptor and HER-2 extracellular domains and prognosis of non-small-cell lung cancer
    • Jacot W, Pujol JL, Boher JM and Lamy PJ: Serum EGF-receptor and HER-2 extracellular domains and prognosis of non-small-cell lung cancer. Br J Cancer 91: 430-433, 2004.
    • (2004) Br J Cancer , vol.91 , pp. 430-433
    • Jacot, W.1    Pujol, J.L.2    Boher, J.M.3    Lamy, P.J.4
  • 33
    • 0033887728 scopus 로고    scopus 로고
    • Different expression of some molecular markers in sporadic cancer of the left and right colon
    • Fric P. Sovova V, Sloncova E, Lojda Z. Jirasek A and Cermak J: Different expression of some molecular markers in sporadic cancer of the left and right colon. Eur J Cancer Prev 9: 265-268. 2000.
    • (2000) Eur J Cancer Prev , vol.9 , pp. 265-268
    • Fric, P.1    Sovova, V.2    Sloncova, E.3    Lojda, Z.4    Jirasek, A.5    Cermak, J.6
  • 34
    • 0027138821 scopus 로고
    • Study of c-erb B-2 protein and epidermal growth factor receptor expression and DNA ploidy pattern in colorectal carcinoma
    • Nakae S. Shimada E and Urakawa T: Study of c-erb B-2 protein and epidermal growth factor receptor expression and DNA ploidy pattern in colorectal carcinoma. J Surg Oncol 54: 246-251. 1993.
    • (1993) J Surg Oncol , vol.54 , pp. 246-251
    • Nakae, S.1    Shimada, E.2    Urakawa, T.3
  • 35
    • 0036251746 scopus 로고    scopus 로고
    • Investigation of the prognostic value of coexpressed erbB family members for the survival of colorectal cancer patients after curative surgery
    • Lee JC. Wang S-T. Chow N-H and Yang HB: Investigation of the prognostic value of coexpressed erbB family members for the survival of colorectal cancer patients after curative surgery. Eur J Cancer 38: 1065-1071. 2002.
    • (2002) Eur J Cancer , vol.38 , pp. 1065-1071
    • Lee, J.C.1    Wang, S.-T.2    Chow, N.-H.3    Yang, H.B.4
  • 36
    • 16544377303 scopus 로고    scopus 로고
    • Epidermal growth factor receptor (EGFR) status in primary colorectal tumours does not correlate with EGFR expression in related metastatic sites: Implications for treatment with EGFR-targeted monoclonal antibodies
    • Scartozzi M. Bearzi I. Berardi R, Mandolesi A. Fabris G and Cascinu S: Epidermal growth factor receptor (EGFR) status in primary colorectal tumours does not correlate with EGFR expression in related metastatic sites: implications for treatment with EGFR-targeted monoclonal antibodies. J Clin Oncol 22: 4720-4726. 2004.
    • (2004) J Clin Oncol , vol.22 , pp. 4720-4726
    • Scartozzi, M.1    Bearzi, I.2    Berardi, R.3    Mandolesi, A.4    Fabris, G.5    Cascinu, S.6
  • 37
    • 0028927012 scopus 로고
    • Altered subcellular location of an activated and tumour-associated epidermal growth factor receptor
    • Ekstrand AJ. Liu L. He J. Hamid ML. Longo N. Collins VP and James CDl: Altered subcellular location of an activated and tumour-associated epidermal growth factor receptor. Oncogene 10: 1455-1460. 1995.
    • (1995) Oncogene , vol.10 , pp. 1455-1460
    • Ekstrand, A.J.1    Liu, L.2    He, J.3    Hamid, M.L.4    Longo, N.5    Collins, V.P.6    James, C.D.7
  • 38
    • 0037139416 scopus 로고    scopus 로고
    • Evidence of high incidence of EGFRvlII expression and coexpression with EGFR in human invasive breast cancer by laser capture microdissection and immunohistochemical analysis
    • Ge H. Gong X and Tang CK: Evidence of high incidence of EGFRvlII expression and coexpression with EGFR in human invasive breast cancer by laser capture microdissection and immunohistochemical analysis. Int J Cancer 98: 357-361, 2002.
    • (2002) Int J Cancer , vol.98 , pp. 357-361
    • Ge, H.1    Gong, X.2    Tang, C.K.3
  • 39
    • 0842305848 scopus 로고    scopus 로고
    • Phosphorylation, but not overexpression of epidermal growth factor receptor is associated with poor prognosis of non-small cell lung cancer patients
    • Kanemalsu T. Yano S. Uehara H. Bando Y and Sone S: Phosphorylation, but not overexpression. of epidermal growth factor receptor is associated with poor prognosis of non-small cell lung cancer patients. Oncol Res 13: 289-298, 2003.
    • (2003) Oncol Res , vol.13 , pp. 289-298
    • Kanemalsu, T.1    Yano, S.2    Uehara, H.3    Bando, Y.4    Sone, S.5
  • 40
    • 0038324367 scopus 로고    scopus 로고
    • Expression of constitutively activated EGFRvlII in non-small cell lung cancer
    • Okamoto I. Kenyon LC. Emlet DR. et al: Expression of constitutively activated EGFRvlII in non-small cell lung cancer. Cancer Sci 94: 50-56. 2003.
    • (2003) Cancer Sci , vol.94 , pp. 50-56
    • Okamoto, I.1    Kenyon, L.C.2    Emlet, D.R.3
  • 42
    • 0036891110 scopus 로고    scopus 로고
    • Epidermal growth factor receptor is a predictor of tumour response in locally advanced rectal cancer patients treated with preoperative radiotherapy
    • Giralt J. Eraso A. Armengol M. Rosello J. Majo J, Ares C, Espin E. Benavente S and De Torres I: Epidermal growth factor receptor is a predictor of tumour response in locally advanced rectal cancer patients treated with preoperative radiotherapy. Int J Radial Oncol Biol Phys 54: 1460-1465. 2002.
    • (2002) Int J Radial Oncol Biol Phys , vol.54 , pp. 1460-1465
    • Giralt, J.1    Eraso, A.2    Armengol, M.3    Rosello, J.4    Majo, J.5    Ares, C.6    Espin, E.7    Benavente, S.8    De Torres, I.9
  • 44
    • 0034855942 scopus 로고    scopus 로고
    • Nuclear localisation of EGF receptor and its potential new role as a transcription factor
    • Lin SY. Makino K. Xia E. et al: Nuclear localisation of EGF receptor and its potential new role as a transcription factor. Nat Cell Biol 3: 802-808. 2001.
    • (2001) Nat Cell Biol , vol.3 , pp. 802-808
    • Lin, S.Y.1    Makino, K.2    Xia, E.3
  • 45
    • 11244280137 scopus 로고    scopus 로고
    • Novel prognostic value of nuclear epidermal growth factor receptor in breast cancer
    • Lo HW. Xia W. Wei Y. et al: Novel prognostic value of nuclear epidermal growth factor receptor in breast cancer. Cancer Res 65: 338-348. 2005.
    • (2005) Cancer Res , vol.65 , pp. 338-348
    • Lo, H.W.1    Xia, W.2    Wei, Y.3
  • 46
    • 1542503756 scopus 로고    scopus 로고
    • Combining the anti-EGFR agent gefitinib with chemotherapy in non-small cell lung cancer: How do we go from INTACT to impact?
    • Baselga J: Combining the anti-EGFR agent gefitinib with chemotherapy in non-small cell lung cancer: how do we go from INTACT to impact? J Clin Oncol 22: 759-761.2004.
    • (2004) J Clin Oncol , vol.22 , pp. 759-761
    • Baselga, J.1
  • 47
    • 3242720345 scopus 로고    scopus 로고
    • Cotuximab monotherapy and cotuximab plus irinotecan in irinotecan-refractory metastatic colorectal cancer
    • Cunningham D, Humblet Y. Siena S, et al: Cotuximab monotherapy and cotuximab plus irinotecan in irinotecan-refractory metastatic colorectal cancer. N Engl J Med 351: 337-345. 2004.
    • (2004) N Engl J Med , vol.351 , pp. 337-345
    • Cunningham, D.1    Humblet, Y.2    Siena, S.3
  • 48
    • 1242315578 scopus 로고    scopus 로고
    • Epidermal growth factor receptor inhibitors in clinical development
    • Dancey J: Epidermal growth factor receptor inhibitors in clinical development. Int J Radial Oncol Biol Phys 58: 1003-1007, 2004.
    • (2004) Int J Radial Oncol Biol Phys , vol.58 , pp. 1003-1007
    • Dancey, J.1
  • 49
    • 3242686833 scopus 로고    scopus 로고
    • The price tag on progress
    • Scharg D: The price tag on progress. N Engl J Med 351: 317-319, 2004.
    • (2004) N Engl J Med , vol.351 , pp. 317-319
    • Scharg, D.1
  • 50
    • 17744371649 scopus 로고    scopus 로고
    • Molecular therapy of head and neck cancer
    • Modjtahedi H: Molecular therapy of head and neck cancer. Cancer Metastasis Rev 24: 129-146, 2005.
    • (2005) Cancer Metastasis Rev , vol.24 , pp. 129-146
    • Modjtahedi, H.1


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