-
1
-
-
79955481383
-
The Notch signaling pathway: Molecular basis of cell context dependency
-
PMID:21126799
-
Schwanbeck R, Martini S, Bernoth K, Just U. The Notch signaling pathway: Molecular basis of cell context dependency. Eur J Cell Biol 2011; 90:572-81; PMID:21126799; http://dx.doi.org/10.1016/j.ejcb.2010.10.004
-
(2011)
Eur J Cell Biol
, vol.90
, pp. 572-581
-
-
Schwanbeck, R.1
Martini, S.2
Bernoth, K.3
Just, U.4
-
2
-
-
0033617522
-
Notch signaling: Cell fate control and signal integration in development
-
PMID:10221902
-
Artavanis-Tsakonas S, Rand MD, Lake RJ. Notch signaling: Cell fate control and signal integration in development. Science 1999; 284:770-6; PMID:10221902; http://dx.doi.org/10.1126/science.284.5415.770
-
(1999)
Science
, vol.284
, pp. 770-776
-
-
Artavanis-Tsakonas, S.1
Rand, M.D.2
Lake, R.J.3
-
3
-
-
0041892131
-
The analysis of a case of continuous variation in Drosophila by a study of its linkage relations
-
Dexter JS. The analysis of a case of continuous variation in Drosophila by a study of its linkage relations. Am Nat 1914; 48:712-58; http://dx.doi.org/10.1086/279446
-
(1914)
Am Nat
, vol.48
, pp. 712-758
-
-
Dexter, J.S.1
-
4
-
-
0025115887
-
A dual function of the Notch gene in Drosophila sensillum development
-
PMID:2227090
-
Hartenstein V, Posakony JW. A dual function of the Notch gene in Drosophila sensillum development. Dev Biol 1990; 142:13-30; PMID:2227090; http://dx.doi.org/10.1016/0012-1606(90)90147-B
-
(1990)
Dev Biol
, vol.142
, pp. 13-30
-
-
Hartenstein, V.1
Posakony, J.W.2
-
5
-
-
0343196671
-
Kuzbanian controls proteolytic processing of Notch and mediates lateral inhibition during Drosophila and vertebrate neurogenesis
-
PMID:9244301
-
Pan D, Rubin GM. Kuzbanian controls proteolytic processing of Notch and mediates lateral inhibition during Drosophila and vertebrate neurogenesis. Cell 1997; 90:271-80; PMID:9244301; http://dx.doi.org/10.1016/S0092-8674(00)80335-9
-
(1997)
Cell
, vol.90
, pp. 271-280
-
-
Pan, D.1
Rubin, G.M.2
-
6
-
-
0025346055
-
Lateral inhibition and the development of the sensory bristles of the adult peripheral nervous system of Drosophila
-
PMID:2205467
-
Simpson P. Lateral inhibition and the development of the sensory bristles of the adult peripheral nervous system of Drosophila. Development 1990; 109:509-19; PMID:2205467
-
(1990)
Development
, vol.109
, pp. 509-519
-
-
Simpson, P.1
-
7
-
-
16244378910
-
Control of cell proliferation in the Drosophila eye by Notch signaling
-
PMID:15809035
-
Baonza A, Freeman M. Control of cell proliferation in the Drosophila eye by Notch signaling. Dev Cell 2005; 8:529-39; PMID:15809035; http://dx.doi.org/10.1016/j.devcel.2005.01.019
-
(2005)
Dev Cell
, vol.8
, pp. 529-539
-
-
Baonza, A.1
Freeman, M.2
-
8
-
-
33846228357
-
Identification of the death zone: A spatially restricted region for programmed cell death that sculpts the fly eye
-
PMID:16710366
-
Monserrate JP, Baker Brachmann C. Identification of the death zone: a spatially restricted region for programmed cell death that sculpts the fly eye. Cell Death Differ 2007; 14:209-17; PMID:16710366; http://dx.doi.org/10.1038/sj.cdd.4401947
-
(2007)
Cell Death Differ
, vol.14
, pp. 209-217
-
-
Monserrate, J.P.1
Baker, B.C.2
-
9
-
-
0035862738
-
Ligand-induced signaling in the absence of furin processing of Notch1
-
PMID:11150244
-
Bush G, diSibio G, Miyamoto A, Denault J-B, Leduc R, Weinmaster G. Ligand-induced signaling in the absence of furin processing of Notch1. Dev Biol 2001; 229:494-502; PMID:11150244; http://dx.doi.org/10.1006/dbio.2000.9992
-
(2001)
Dev Biol
, vol.229
, pp. 494-502
-
-
Bush, G.1
Disibio, G.2
Miyamoto, A.3
Denault, J.-B.4
Leduc, R.5
Weinmaster, G.6
-
10
-
-
69249209928
-
In vivo analysis of the Notch receptor S1 cleavage
-
PMID:19701455
-
Lake RJ, Grimm LM, Veraksa A, Banos A, Artavanis- Tsakonas S. In vivo analysis of the Notch receptor S1 cleavage. PLoS ONE 2009; 4:e6728; PMID:19701455; http://dx.doi.org/10.1371/journal.pone.0006728
-
(2009)
PLoS ONE
, vol.4
-
-
Lake, R.J.1
Grimm, L.M.2
Veraksa, A.3
Banos, A.4
Artavanis-Tsakonas, S.5
-
11
-
-
0034671686
-
Notch signaling: From the outside in
-
PMID:11112321
-
Mumm JS, Kopan R. Notch signaling: From the outside in. Dev Biol 2000; 228:151-65; PMID:11112321; http://dx.doi.org/10.1006/dbio.2000.9960
-
(2000)
Dev Biol
, vol.228
, pp. 151-165
-
-
Mumm, J.S.1
Kopan, R.2
-
12
-
-
0034729722
-
Mastermind is a putative activator for Notch
-
PMID:10898989
-
Petcherski AG, Kimble J. Mastermind is a putative activator for Notch. Curr Biol 2000; 10:R471-3; PMID:10898989; http://dx.doi.org/10.1016/S0960-9822(00)00577-7
-
(2000)
Curr Biol
, vol.10
-
-
Petcherski, A.G.1
Kimble, J.2
-
13
-
-
33846968807
-
DSL ligand endocytosis physically dissociates Notch1 heterodimers before activating proteolysis can occur
-
PMID:17296795
-
Nichols JT, Miyamoto A, Olsen SL, D'Souza B, Yao C, Weinmaster G. DSL ligand endocytosis physically dissociates Notch1 heterodimers before activating proteolysis can occur. J Cell Biol 2007; 176:445-58; PMID:17296795; http://dx.doi.org/10.1083/jcb.200609014
-
(2007)
J Cell Biol
, vol.176
, pp. 445-458
-
-
Nichols, J.T.1
Miyamoto, A.2
Olsen, S.L.3
D'souza, B.4
Yao, C.5
Weinmaster, G.6
-
14
-
-
70350536784
-
Selective use of ADAM10 and ADAM17 in activation of Notch1 signaling
-
PMID:19704010
-
Bozkulak EC, Weinmaster G. Selective use of ADAM10 and ADAM17 in activation of Notch1 signaling. Mol Cell Biol 2009; 29:5679-95; PMID:19704010; http://dx.doi.org/10.1128/MCB.00406-09
-
(2009)
Mol Cell Biol
, vol.29
, pp. 5679-5695
-
-
Bozkulak, E.C.1
Weinmaster, G.2
-
15
-
-
66149151737
-
Structure of the Notch1- negative regulatory region: Implications for normal activation and pathogenic signaling in T-ALL
-
PMID:19075186
-
Gordon WR, Roy M, Vardar-Ulu D, Garfinkel M, Mansour MR, Aster JC, et al. Structure of the Notch1- negative regulatory region: Implications for normal activation and pathogenic signaling in T-ALL. Blood 2009; 113:4381-90; PMID:19075186; http://dx.doi.org/10.1182/blood-2008-08-174748
-
(2009)
Blood
, vol.113
, pp. 4381-4390
-
-
Gordon, W.R.1
Roy, M.2
Vardar-Ulu, D.3
Garfinkel, M.4
Mansour, M.R.5
Aster, J.C.6
-
16
-
-
65549121943
-
Notch signaling: The core pathway and its posttranslational regulation
-
PMID:19460341
-
Fortini ME. Notch signaling: The core pathway and its posttranslational regulation. Dev Cell 2009; 16:633-47; PMID:19460341; http://dx.doi.org/10.1016/j.devcel.2009.03.010
-
(2009)
Dev Cell
, vol.16
, pp. 633-647
-
-
Fortini, M.E.1
-
17
-
-
67949120665
-
Endocytic regulation of Notch signaling
-
PMID:19447603
-
Fortini ME, Bilder D. Endocytic regulation of Notch signaling. Curr Opin Genet Dev 2009; 19:323-8; PMID:19447603; http://dx.doi.org/10.1016/j.gde.2009.04.005
-
(2009)
Curr Opin Genet Dev
, vol.19
, pp. 323-328
-
-
Fortini, M.E.1
Bilder, D.2
-
18
-
-
79955134314
-
Ral GTPase promotes asymmetric Notch activation in the Drosophila eye in response to Frizzled/PCP signaling by repressing ligand-independent receptor activation
-
PMID:21350007
-
Cho B, Fischer JA. Ral GTPase promotes asymmetric Notch activation in the Drosophila eye in response to Frizzled/PCP signaling by repressing ligand-independent receptor activation. Development 2011; 138:1349-59; PMID:21350007; http://dx.doi.org/10.1242/dev.056002
-
(2011)
Development
, vol.138
, pp. 1349-1359
-
-
Cho, B.1
Fischer, J.A.2
-
19
-
-
0029788321
-
KUZ, a conserved metalloprotease-disintegrin protein with two roles in Drosophila neurogenesis
-
PMID:8703057
-
Rooke J, Pan D, Xu T, Rubin GM. KUZ, a conserved metalloprotease-disintegrin protein with two roles in Drosophila neurogenesis. Science 1996; 273:1227-31; PMID:8703057; http://dx.doi.org/10.1126/science.273.5279.1227
-
(1996)
Science
, vol.273
, pp. 1227-1231
-
-
Rooke, J.1
Pan, D.2
Xu, T.3
Rubin, G.M.4
-
20
-
-
0031457037
-
The metalloproteasedisintegrin Kuzbanian participates in Notch activation during growth and patterning of Drosophila imaginal discs
-
PMID:9428413
-
Sotillos S, Roch F, Campuzano S. The metalloproteasedisintegrin Kuzbanian participates in Notch activation during growth and patterning of Drosophila imaginal discs. Development 1997; 124:4769-79; PMID:9428413
-
(1997)
Development
, vol.124
, pp. 4769-4779
-
-
Sotillos, S.1
Roch, F.2
Campuzano, S.3
-
21
-
-
0037080699
-
Kuzbanian-mediated cleavage of Drosophila Notch
-
PMID:11799064
-
Lieber T, Kidd S, Young MW. kuzbanian-mediated cleavage of Drosophila Notch. Genes Dev 2002; 16: 209-21; PMID:11799064; http://dx.doi.org/10.1101/gad.942302
-
(2002)
Genes Dev
, vol.16
, pp. 209-221
-
-
Lieber, T.1
Kidd, S.2
Young, M.W.3
-
22
-
-
0033868818
-
A novel proteolytic cleavage involved in Notch signaling: The role of the disintegrinmetalloprotease TACE
-
PMID:10882063
-
Brou C, Logeat F, Gupta N, Bessia C, LeBail O, Doedens JR, et al. A novel proteolytic cleavage involved in Notch signaling: The role of the disintegrinmetalloprotease TACE. Mol Cell 2000; 5:207-16; PMID:10882063; http://dx.doi.org/10.1016/S1097-2765(00)80417-7
-
(2000)
Mol Cell
, vol.5
, pp. 207-216
-
-
Brou, C.1
Logeat, F.2
Gupta, N.3
Bessia, C.4
Lebail, O.5
Doedens, J.R.6
-
23
-
-
27744480285
-
Evidence for functional redundancy between C. elegans ADAM proteins SUP-17/Kuzbanian and ADM-4/TACE
-
PMID:16197940
-
Jarriault S, Greenwald I. Evidence for functional redundancy between C. elegans ADAM proteins SUP-17/Kuzbanian and ADM-4/TACE. Dev Biol 2005; 287:1-10; PMID:16197940; http://dx.doi.org/10.1016/j.ydbio.2005.08.014
-
(2005)
Dev Biol
, vol.287
, pp. 1-10
-
-
Jarriault, S.1
Greenwald, I.2
-
24
-
-
0033867521
-
A ligand-induced extracellular cleavage regulates c-secretase-like proteolytic activation of Notch1
-
PMID:10882062
-
Mumm JS, Schroeter EH, Saxena MT, Griesemer A, Tian X, Pan DJ, et al. A ligand-induced extracellular cleavage regulates c-secretase-like proteolytic activation of Notch1. Mol Cell 2000; 5:197-206; PMID:10882062; http://dx.doi.org/10.1016/S1097-2765(00)80416-5
-
(2000)
Mol Cell
, vol.5
, pp. 197-206
-
-
Mumm, J.S.1
Schroeter, E.H.2
Saxena, M.T.3
Griesemer, A.4
Tian, X.5
Pan, D.J.6
-
25
-
-
67349226089
-
Identification of ADAM10 as a major TNF sheddase in ADAM17-deficient fibroblasts
-
PMID:19346138
-
Mezyk-Kopeć R, Bzowska M, Stalinska K, Chelmicki T, Podkalicki M, Jucha J, et al. Identification of ADAM10 as a major TNF sheddase in ADAM17-deficient fibroblasts. Cytokine 2009; 46:309-15; PMID:19346138; http://dx.doi.org/10.1016/j.cyto.2009.03.002
-
(2009)
Cytokine
, vol.46
, pp. 309-315
-
-
Mezyk-Kopeć, R.1
Bzowska, M.2
Stalinska, K.3
Chelmicki, T.4
Podkalicki, M.5
Jucha, J.6
-
26
-
-
0032515018
-
An essential role for ectodomain shedding in mammalian development
-
PMID:9812885
-
Peschon JJ, Slack JL, Reddy P, Stocking KL, Sunnarborg SW, Lee DC, et al. An essential role for ectodomain shedding in mammalian development. Science 1998; 282:1281-4; PMID:9812885; http://dx.doi.org/10.1126/science.282.5392.1281
-
(1998)
Science
, vol.282
, pp. 1281-1284
-
-
Peschon, J.J.1
Slack, J.L.2
Reddy, P.3
Stocking, K.L.4
Sunnarborg, S.W.5
Lee, D.C.6
-
27
-
-
0036796421
-
The disintegrin/ metalloprotease ADAM 10 is essential for Notch signalling but not for α-secretase activity in fibroblasts
-
PMID:12354787
-
Hartmann D, de Strooper B, Serneels L, Craessaerts K, Herreman A, Annaert W, et al. The disintegrin/ metalloprotease ADAM 10 is essential for Notch signalling but not for α-secretase activity in fibroblasts. Hum Mol Genet 2002; 11:2615-24; PMID:12354787; http://dx.doi.org/10.1093/hmg/11.21.2615
-
(2002)
Hum Mol Genet
, vol.11
, pp. 2615-2624
-
-
Hartmann, D.1
de Strooper, B.2
Serneels, L.3
Craessaerts, K.4
Herreman, A.5
Annaert, W.6
-
28
-
-
79952559441
-
Adam10 is essential for early embryonic cardiovascular development
-
PMID:20803506
-
Zhang C, Tian L, Chi C, Wu X, Yang X, Han M, et al. Adam10 is essential for early embryonic cardiovascular development. Dev Dyn 2010; 239:2594-602; PMID:20803506; http://dx.doi.org/10.1002/dvdy.22391
-
(2010)
Dev Dyn
, vol.239
, pp. 2594-2602
-
-
Zhang, C.1
Tian, L.2
Chi, C.3
Wu, X.4
Yang, X.5
Han, M.6
-
29
-
-
78751520783
-
The disintegrin/ metalloproteinase Adam10 is essential for epidermal integrity and Notch-mediated signaling
-
PMID:21205794
-
Weber S, Niessen MT, Prox J, Lullmann-Rauch R, Schmitz A, Schwanbeck R, et al. The disintegrin/ metalloproteinase Adam10 is essential for epidermal integrity and Notch-mediated signaling. Development 2011; 138:495-505; PMID:21205794; http://dx.doi.org/10.1242/dev.055210
-
(2011)
Development
, vol.138
, pp. 495-505
-
-
Weber, S.1
Niessen, M.T.2
Prox, J.3
Lullmann-Rauch, R.4
Schmitz, A.5
Schwanbeck, R.6
-
30
-
-
37449010541
-
The multifaceted role of Notch in cardiac development and disease
-
PMID:18071321
-
High FA, Epstein JA. The multifaceted role of Notch in cardiac development and disease. Nat Rev Genet 2008; 9:49-61; PMID:18071321; http://dx.doi.org/10.1038/nrg2279
-
(2008)
Nat Rev Genet
, vol.9
, pp. 49-61
-
-
High, F.A.1
Epstein, J.A.2
-
31
-
-
45149117788
-
Notch-deficient skin induces a lethal systemic B-lymphoproliferative disorder by secreting TSLP, a sentinel for epidermal integrity
-
PMID:18507503
-
Demehri S, Liu Z, Lee J, Lin M-H, Crosby SD, Roberts CJ, et al. Notch-deficient skin induces a lethal systemic B-lymphoproliferative disorder by secreting TSLP, a sentinel for epidermal integrity. PLoS Biol 2008; 6:e123; PMID:18507503; http://dx.doi.org/10.1371/journal.pbio.0060123
-
(2008)
PLoS Biol
, vol.6
-
-
Demehri, S.1
Liu, Z.2
Lee, J.3
Lin, M.-H.4
Crosby, S.D.5
Roberts, C.J.6
-
32
-
-
0037370310
-
Notch1 functions as a tumor suppressor in mouse skin
-
PMID:12590261
-
Nicolas M, Wolfer A, Raj K, Kummer JA, Mill P, van Noort M, et al. Notch1 functions as a tumor suppressor in mouse skin. Nat Genet 2003; 33:416-21; PMID:12590261; http://dx.doi.org/10.1038/ng1099
-
(2003)
Nat Genet
, vol.33
, pp. 416-421
-
-
Nicolas, M.1
Wolfer, A.2
Raj, K.3
Kummer, J.A.4
Mill, P.5
van Noort, M.6
-
33
-
-
71449113533
-
Metalloprotease ADAM10 is required for Notch1 site 2 cleavage
-
PMID:19726682
-
van Tetering G, van Diest P, Verlaan I, van der Wall E, Kopan R, Vooijs M. Metalloprotease ADAM10 is required for Notch1 site 2 cleavage. J Biol Chem 2009; 284:31018-27; PMID:19726682; http://dx.doi.org/10.1074/jbc.M109.006775
-
(2009)
J Biol Chem
, vol.284
, pp. 31018-31027
-
-
van Tetering, G.1
van Diest, P.2
Verlaan, I.3
van der Wall, E.4
Kopan, R.5
Vooijs, M.6
-
34
-
-
47749118343
-
Kuz and TACE can activate Notch independent of ligand
-
PMID:18535782
-
Delwig A, Rand M. Kuz and TACE can activate Notch independent of ligand. Cell Mol Life Sci 2008; 65: 2232-43; PMID:18535782; http://dx.doi.org/10.1007/ s00018-008-8127-x
-
(2008)
Cell Mol Life Sci
, vol.65
, pp. 2232-2243
-
-
Delwig, A.1
Rand, M.2
-
35
-
-
0033974972
-
Calcium depletion dissociates and activates heterodimeric Notch receptors
-
PMID:10669757
-
Rand MD, Grimm LM, Artavanis-Tsakonas S, Patriub V, Blacklow SC, Sklar J, et al. Calcium depletion dissociates and activates heterodimeric Notch receptors. Mol Cell Biol 2000; 20:1825-35; PMID:10669757; http://dx.doi.org/10.1128/MCB.20.5.1825-1835.2000
-
(2000)
Mol Cell Biol
, vol.20
, pp. 1825-1835
-
-
Rand, M.D.1
Grimm, L.M.2
Artavanis-Tsakonas, S.3
Patriub, V.4
Blacklow, S.C.5
Sklar, J.6
-
36
-
-
5044225888
-
Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia
-
PMID:15472075
-
Weng AP, Ferrando AA, Lee W, Morris JP, Silverman LB, Sanchez-Irizarry C, et al. Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia. Science 2004; 306:269-71; PMID:15472075; http://dx.doi.org/10.1126/science.1102160
-
(2004)
Science
, vol.306
, pp. 269-271
-
-
Weng, A.P.1
Ferrando, A.A.2
Lee, W.3
Morris, J.P.4
Silverman, L.B.5
Sanchez-Irizarry, C.6
-
37
-
-
8444247084
-
Modulation of Notch processing by c-secretase inhibitors causes intestinal goblet cell metaplasia and induction of genes known to specify gut secretory lineage differentiation
-
PMID:15319485
-
Milano J, McKay J, Dagenais C, Foster-Brown L, Pognan F, Gadient R, et al. Modulation of Notch processing by c-secretase inhibitors causes intestinal goblet cell metaplasia and induction of genes known to specify gut secretory lineage differentiation. Toxicol Sci 2004; 82:341-58; PMID:15319485; http://dx.doi.org/10.1093/toxsci/kfh254
-
(2004)
Toxicol Sci
, vol.82
, pp. 341-358
-
-
Milano, J.1
McKay, J.2
Dagenais, C.3
Foster-Brown, L.4
Pognan, F.5
Gadient, R.6
-
38
-
-
34948908663
-
Mutational loss of PTEN induces resistance to NOTCH1 inhibition in T-cell leukemia
-
PMID:17873882
-
Palomero T, Sulis ML, Cortina M, Real PJ, Barnes K, Ciofani M, et al. Mutational loss of PTEN induces resistance to NOTCH1 inhibition in T-cell leukemia. Nat Med 2007; 13:1203-10; PMID:17873882; http://dx.doi.org/10.1038/nm1636
-
(2007)
Nat Med
, vol.13
, pp. 1203-1210
-
-
Palomero, T.1
Sulis, M.L.2
Cortina, M.3
Real, P.J.4
Barnes, K.5
Ciofani, M.6
-
39
-
-
80052953314
-
The sheddase activity of ADAM17/TACE is regulated by the tetraspanin CD9
-
PMID:20703892
-
Gutiérrez-López M, Gilsanz A, Yáñez-Mó M, Ovalle S, Lafuente E, Domínguez C, et al. The sheddase activity of ADAM17/TACE is regulated by the tetraspanin CD9. Cell Mol Life Sci 2011; 68:3275-92; PMID:20703892; http://dx.doi.org/10.1007/s00018-011-0639-0
-
(2011)
Cell Mol Life Sci
, vol.68
, pp. 3275-3292
-
-
Gutiérrez-López, M.1
Gilsanz, A.2
Yáñez-Mó, M.3
Ovalle, S.4
Lafuente, E.5
Domínguez, C.6
-
40
-
-
77954896191
-
ADAMs and protein disulfide isomerase: The key to regulated cell-surface protein ectodomain shedding?
-
PMID:20504280
-
Bass R, Edwards DR. ADAMs and protein disulfide isomerase: The key to regulated cell-surface protein ectodomain shedding? Biochem J 2010; 428:e3-5; PMID:20504280; http://dx.doi.org/10.1042/BJ20100568
-
(2010)
Biochem J
, vol.428
-
-
Bass, R.1
Edwards, D.R.2
|