-
2
-
-
0026075015
-
-
S. Artavanis-Tsakonas and P. Simpson, Trends Genet. 7, 403 (1991); J. A. Campos-Ortega, in The Development of Drosophila melanogaster, M. Bate and A. Martinez Arias, Eds. (Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY, 1993), vol. II, pp. 1091-1130; Y. N. Jan and L. Y. Jan, in ibid., pp. 1207-1244; S. Romani, S. Campuzano, E. R. Macagno, J. Modolell, Genes Dev. 3, 997 (1989); S. Artavanis-Tsakonas, K. Matsuno, M. E. Fortini, Science 268, 225 (1995).
-
(1991)
Trends Genet.
, vol.7
, pp. 403
-
-
Artavanis-Tsakonas, S.1
Simpson, P.2
-
3
-
-
0026075015
-
-
M. Bate and A. Martinez Arias, Eds. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY
-
S. Artavanis-Tsakonas and P. Simpson, Trends Genet. 7, 403 (1991); J. A. Campos-Ortega, in The Development of Drosophila melanogaster, M. Bate and A. Martinez Arias, Eds. (Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY, 1993), vol. II, pp. 1091-1130; Y. N. Jan and L. Y. Jan, in ibid., pp. 1207-1244; S. Romani, S. Campuzano, E. R. Macagno, J. Modolell, Genes Dev. 3, 997 (1989); S. Artavanis-Tsakonas, K. Matsuno, M. E. Fortini, Science 268, 225 (1995).
-
(1993)
The Development of Drosophila Melanogaster
, vol.2
, pp. 1091-1130
-
-
Campos-Ortega, J.A.1
-
4
-
-
0026075015
-
-
S. Artavanis-Tsakonas and P. Simpson, Trends Genet. 7, 403 (1991); J. A. Campos-Ortega, in The Development of Drosophila melanogaster, M. Bate and A. Martinez Arias, Eds. (Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY, 1993), vol. II, pp. 1091-1130; Y. N. Jan and L. Y. Jan, in ibid., pp. 1207-1244; S. Romani, S. Campuzano, E. R. Macagno, J. Modolell, Genes Dev. 3, 997 (1989); S. Artavanis-Tsakonas, K. Matsuno, M. E. Fortini, Science 268, 225 (1995).
-
The Development of Drosophila Melanogaster
, pp. 1207-1244
-
-
Jan, Y.N.1
Jan, L.Y.2
-
5
-
-
0024693749
-
-
S. Artavanis-Tsakonas and P. Simpson, Trends Genet. 7, 403 (1991); J. A. Campos-Ortega, in The Development of Drosophila melanogaster, M. Bate and A. Martinez Arias, Eds. (Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY, 1993), vol. II, pp. 1091-1130; Y. N. Jan and L. Y. Jan, in ibid., pp. 1207-1244; S. Romani, S. Campuzano, E. R. Macagno, J. Modolell, Genes Dev. 3, 997 (1989); S. Artavanis-Tsakonas, K. Matsuno, M. E. Fortini, Science 268, 225 (1995).
-
(1989)
Genes Dev.
, vol.3
, pp. 997
-
-
Romani, S.1
Campuzano, S.2
Macagno, E.R.3
Modolell, J.4
-
6
-
-
0028943243
-
-
S. Artavanis-Tsakonas and P. Simpson, Trends Genet. 7, 403 (1991); J. A. Campos-Ortega, in The Development of Drosophila melanogaster, M. Bate and A. Martinez Arias, Eds. (Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY, 1993), vol. II, pp. 1091-1130; Y. N. Jan and L. Y. Jan, in ibid., pp. 1207-1244; S. Romani, S. Campuzano, E. R. Macagno, J. Modolell, Genes Dev. 3, 997 (1989); S. Artavanis-Tsakonas, K. Matsuno, M. E. Fortini, Science 268, 225 (1995).
-
(1995)
Science
, vol.268
, pp. 225
-
-
Artavanis-Tsakonas, S.1
Matsuno, K.2
Fortini, M.E.3
-
7
-
-
0001067788
-
-
V. B. Wigglesworth, J. Exp. Biol. 17, 180; P. Simpson, Development 109, 509 (1990); C. Q. Doe and C. S. Goodman, Dev. Biol. 111, 206 (1985).
-
J. Exp. Biol.
, vol.17
, pp. 180
-
-
Wigglesworth, V.B.1
-
8
-
-
0025346055
-
-
V. B. Wigglesworth, J. Exp. Biol. 17, 180; P. Simpson, Development 109, 509 (1990); C. Q. Doe and C. S. Goodman, Dev. Biol. 111, 206 (1985).
-
(1990)
Development
, vol.109
, pp. 509
-
-
Simpson, P.1
-
9
-
-
0022414029
-
-
V. B. Wigglesworth, J. Exp. Biol. 17, 180; P. Simpson, Development 109, 509 (1990); C. Q. Doe and C. S. Goodman, Dev. Biol. 111, 206 (1985).
-
(1985)
Dev. Biol.
, vol.111
, pp. 206
-
-
Doe, C.Q.1
Goodman, C.S.2
-
10
-
-
0027267041
-
-
T. Xu and G. M. Rubin, Development 117, 1223 (1993); T. Xu and S. Harrison Methods Cell Biol. 44, 655 (1994).
-
(1993)
Development
, vol.117
, pp. 1223
-
-
Xu, T.1
Rubin, G.M.2
-
12
-
-
9544257615
-
-
note
-
e29-4 was used to screen a Drosophila total imaginai disc cDNA library (14). A group of two overlapping 1,2-kb cDNAs mapping to this region was recovered; a full-length kuz cDNA, NB1, was isolated from an embryonic cDNA library (14) with the small cDNA clones as probes. Detailed genetic and allelic information will be described elsewhere (J. Rooke and T. Xu, unpublished results), kuz cDNA GenBank accession number: U60591.
-
-
-
-
15
-
-
0024285551
-
-
E. Bier, L. Ackerman, S. Barbel, L. Jan, Y. Nung Jan, Science 240, 913 (1988); S. Robinow and K. White, J. Neurobiol. 22, 443 (1991).
-
(1988)
Science
, vol.240
, pp. 913
-
-
Bier, E.1
Ackerman, L.2
Barbel, S.3
Jan, L.4
Nung Jan, Y.5
-
16
-
-
0025744938
-
-
E. Bier, L. Ackerman, S. Barbel, L. Jan, Y. Nung Jan, Science 240, 913 (1988); S. Robinow and K. White, J. Neurobiol. 22, 443 (1991).
-
(1991)
J. Neurobiol.
, vol.22
, pp. 443
-
-
Robinow, S.1
White, K.2
-
17
-
-
0020529437
-
-
R. Lehmann, F. Jimenez, U. Dietrich, J. A. Campos-Ortega, Roux's Arch. Dev. Biol. 192, 62 (1983).
-
(1983)
Roux's Arch. Dev. Biol.
, vol.192
, pp. 62
-
-
Lehmann, R.1
Jimenez, F.2
Dietrich, U.3
Campos-Ortega, J.A.4
-
18
-
-
0024447494
-
-
M. Bourouis, P. Heitzler, M. el Messal, P. Simpson, Nature 341, 442 (1989).
-
(1989)
Nature
, vol.341
, pp. 442
-
-
Bourouis, M.1
Heitzler, P.2
El Messal, M.3
Simpson, P.4
-
19
-
-
9544245136
-
-
note
-
At least 50 kuz clones with mutant bristle clusters were examined with light dissecting and compound microscopes. Twenty clones were further examined by SEM.
-
-
-
-
22
-
-
0023772113
-
-
The imaginai disc cDNA library was from A. Cowman. The embryonic cDNA library was prepared by N. B. Brown and F. C. Kafatos, J. Mol. Biol. 203, 425 (1988).
-
(1988)
J. Mol. Biol.
, vol.203
, pp. 425
-
-
Brown, N.B.1
Kafatos, F.C.2
-
23
-
-
0028820623
-
-
T. G. Wolfsberg, P. Primakoff, D. G. Myles, J. M. White, J. Cell Biol. 131, 275 (1995).
-
(1995)
J. Cell Biol.
, vol.131
, pp. 275
-
-
Wolfsberg, T.G.1
Primakoff, P.2
Myles, D.G.3
White, J.M.4
-
25
-
-
0028150753
-
-
S. Niewiarowski, M. A. McLane, M. Kloczewiak, G. J. Stewart, Semin. Hematol. 31, 289 (1994).
-
(1994)
Semin. Hematol.
, vol.31
, pp. 289
-
-
Niewiarowski, S.1
McLane, M.A.2
Kloczewiak, M.3
Stewart, G.J.4
-
26
-
-
0025371355
-
-
C. P. Blobel, D. G. Myles, P. Primakoff, J. M. White, J. Cell Biol. 111, 69 (1990); M. P, Neeper and M. A. Jacobson, Nucleic Acids Res. 18, 4255 (1990); L. C. Au et al., Biochem. Biophys. Res. Commun. 181, 585 (1991).
-
(1990)
J. Cell Biol.
, vol.111
, pp. 69
-
-
Blobel, C.P.1
Myles, D.G.2
Primakoff, P.3
White, J.M.4
-
27
-
-
0025365318
-
-
C. P. Blobel, D. G. Myles, P. Primakoff, J. M. White, J. Cell Biol. 111, 69 (1990); M. P, Neeper and M. A. Jacobson, Nucleic Acids Res. 18, 4255 (1990); L. C. Au et al., Biochem. Biophys. Res. Commun. 181, 585 (1991).
-
(1990)
Nucleic Acids Res.
, vol.18
, pp. 4255
-
-
Neeper, M.P.1
Jacobson, M.A.2
-
28
-
-
0026348765
-
-
C. P. Blobel, D. G. Myles, P. Primakoff, J. M. White, J. Cell Biol. 111, 69 (1990); M. P, Neeper and M. A. Jacobson, Nucleic Acids Res. 18, 4255 (1990); L. C. Au et al., Biochem. Biophys. Res. Commun. 181, 585 (1991).
-
(1991)
Biochem. Biophys. Res. Commun.
, vol.181
, pp. 585
-
-
Au, L.C.1
-
31
-
-
0001624107
-
-
SEM, embryo staining, and adult eye sections were carried out following standard procedures. A. Tomlinson and D. F. Ready, Dev. Biol. 123, 264 (1987); T. Xu and S. Artavanis-Tsakonas, Genetics 126, 665 (1990).
-
(1987)
Dev. Biol.
, vol.123
, pp. 264
-
-
Tomlinson, A.1
Ready, D.F.2
-
32
-
-
0025087027
-
-
SEM, embryo staining, and adult eye sections were carried out following standard procedures. A. Tomlinson and D. F. Ready, Dev. Biol. 123, 264 (1987); T. Xu and S. Artavanis-Tsakonas, Genetics 126, 665 (1990).
-
(1990)
Genetics
, vol.126
, pp. 665
-
-
Xu, T.1
Artavanis-Tsakonas, S.2
-
33
-
-
0026695342
-
-
e29 4 ck FRT40A/CyO males. About half of the embryos from these crosses exhibited the severe neurogenic phenotype described (Fig. 1G). The other half of the embryos exhibited an intermediate neurogenic phenotype (Fig. 1F), the same phenotype observed in all embryos produced by mating with wild-type males. The extent of the neurogenic phenotype caused by the hypomorphic kuz alleles varies between the wild type and the kuz null, but the correlation between the neural hyperplasia and the epidermal hypotrophy was always observed.
-
(1992)
Genetics
, vol.131
, pp. 643
-
-
Chou, T.-B.1
Perrimon, N.2
-
34
-
-
0028807402
-
-
T. Yagami-Hiromasa et al., Nature 377, 652 (1995); C. P. Blobel et al., ibid. 356, 248 (1992); M. J. Paine, H. P. Desmond, R. D. Theakston, J. M. Crampton, J. Biol. Chem. 267, 22869 (1992); R. J. Shebuski, D. R. Ramjit, G. H. Bencen, M. A. Polokoff, ibid., 264, 21550 (1989).
-
(1995)
Nature
, vol.377
, pp. 652
-
-
Yagami-Hiromasa, T.1
-
35
-
-
0026510747
-
-
T. Yagami-Hiromasa et al., Nature 377, 652 (1995); C. P. Blobel et al., ibid. 356, 248 (1992); M. J. Paine, H. P. Desmond, R. D. Theakston, J. M. Crampton, J. Biol. Chem. 267, 22869 (1992); R. J. Shebuski, D. R. Ramjit, G. H. Bencen, M. A. Polokoff, ibid., 264, 21550 (1989).
-
(1992)
Nature
, vol.356
, pp. 248
-
-
Blobel, C.P.1
-
36
-
-
0026495409
-
-
T. Yagami-Hiromasa et al., Nature 377, 652 (1995); C. P. Blobel et al., ibid. 356, 248 (1992); M. J. Paine, H. P. Desmond, R. D. Theakston, J. M. Crampton, J. Biol. Chem. 267, 22869 (1992); R. J. Shebuski, D. R. Ramjit, G. H. Bencen, M. A. Polokoff, ibid., 264, 21550 (1989).
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 22869
-
-
Paine, M.J.1
Desmond, H.P.2
Theakston, R.D.3
Crampton, J.M.4
-
37
-
-
0024852988
-
-
T. Yagami-Hiromasa et al., Nature 377, 652 (1995); C. P. Blobel et al., ibid. 356, 248 (1992); M. J. Paine, H. P. Desmond, R. D. Theakston, J. M. Crampton, J. Biol. Chem. 267, 22869 (1992); R. J. Shebuski, D. R. Ramjit, G. H. Bencen, M. A. Polokoff, ibid., 264, 21550 (1989).
-
(1989)
J. Biol. Chem.
, vol.264
, pp. 21550
-
-
Shebuski, R.J.1
Ramjit, D.R.2
Bencen, G.H.3
Polokoff, M.A.4
-
39
-
-
9544225407
-
-
note
-
We thank W, Yu and W. Y. Wang for technical assistance and P. Heitzler and the Bloomington Stock Center for fly strains. D.P. was supported by a Jane Coffin Childs Memorial Fund Postdoctoral Fellowship. G.M.R. is an investigator of the Howard Hughes Medical Institute. This work was initiated by T.X. as a Helen Hay Whitney Fellow in the G.M.R laboratory. J.R. was supported by an NSF fellowship. Supported by grants from the Pew Scholars Program in the Biomedical Sciences and the Lucille P. Markey Charitable Trust to T.X.
-
-
-
|