A new mode of B12 binding and the direct participation of a potassium ion in enzyme catalysis: X-ray structure of diol dehydratase

Structure

Volumn 7, Issue 8, 1999, Pages 997-1008

  Shibata, Naoki ^a   Masuda, Jun ^a   Tobimatsu, Takamasa ^b   Toraya, Tetsuo ^b   Suto, Kyoko ^a   Morimoto, Yukio ^a   Yasuoka, Noritake ^a  

^a UNIVERSITY OF HYOGO   (Japan)

^b OKAYAMA UNIVERSITY   (Japan)

Author keywords

B12 enzyme; Diol dehydratase; Radicals; Reaction mechanism; TIM barrel

Indexed keywords

ALDEHYDE; CARBON; COBALAMIN; COBALT; COBAMAMIDE; CYANOCOBALAMIN; HYDROLYASE; HYDROXYL GROUP; POTASSIUM ION; PROPYLENE GLYCOL; POTASSIUM; PROPANEDIOL DEHYDRATASE;

AMINO ACID SEQUENCE; ARTICLE; CATALYSIS; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME MECHANISM; ENZYME STRUCTURE; HYDROGEN BOND; PRIORITY JOURNAL; PROTEIN SECONDARY STRUCTURE; STRUCTURE ACTIVITY RELATION; X RAY CRYSTALLOGRAPHY; BINDING SITE; CHEMICAL STRUCTURE; CHEMISTRY; METABOLISM; MOLECULAR GENETICS; PROTEIN BINDING;

AMINO ACID SEQUENCE; BINDING SITES; CATALYSIS; COBAMIDES; CRYSTALLOGRAPHY, X-RAY; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; POTASSIUM; PROPANEDIOL DEHYDRATASE; PROTEIN BINDING; PROTEIN STRUCTURE, SECONDARY;

EID: 0033567082     PISSN: 09692126     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0969-2126(99)80126-9     Document Type: Article

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