Molecular basis for dysfunction of some mutant forms of methylmalonyl-CoA mutase: Deductions from the structure of methionine synthase

Proceedings of the National Academy of Sciences of the United States of America

Volumn 93, Issue 11, 1996, Pages 5550-5555

  Drennan, Catherine Luschinsky ^a   Matthews, Rowena G ^a   Rosenblatt, David S ^b   Ledley, Fred D ^c   Fenton, Wayne A ^d   Ludwig, Martha L ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^b MCGILL UNIVERSITY   (Canada)

^c BAYLOR COLLEGE OF MEDICINE   (United States)

^d YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

METHIONINE SYNTHASE; METHYLMALONYL COENZYME A MUTASE;

AMINO ACID SUBSTITUTION; ARTICLE; CARBOXY TERMINAL SEQUENCE; ENZYME ACTIVITY; ESCHERICHIA COLI; GENE MUTATION; HUMAN; METHYLMALONIC ACIDURIA; NONHUMAN; NUCLEIC ACID BASE SUBSTITUTION; PATHOGENESIS; PRIORITY JOURNAL; SEQUENCE ANALYSIS; STRUCTURE ACTIVITY RELATION; X RAY CRYSTALLOGRAPHY;

5-METHYLTETRAHYDROFOLATE-HOMOCYSTEINE S-METHYLTRANSFERASE; ALLELES; AMINO ACID SEQUENCE; ANIMALS; BACTERIA; BINDING SITES; CAENORHABDITIS ELEGANS; ESCHERICHIA COLI; HETEROZYGOTE; HUMANS; METABOLISM, INBORN ERRORS; METHYLMALONIC ACID; METHYLMALONYL-COA MUTASE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; NUCLEOTIDES; POINT MUTATION; POLYMORPHISM, GENETIC; PROTEIN CONFORMATION; SEQUENCE HOMOLOGY, AMINO ACID; VITAMIN B 12;

ESCHERICHIA COLI;

EID: 0029950708     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.93.11.5550     Document Type: Article

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