-
1
-
-
0015796295
-
Hyperlipidemia in coronary heart disease. II. Genetic analysis of lipid levels in 176 families and delineation of a new inherited disorder, combined hyperlipidemia
-
Goldstein, J. L., Schrott, H. G., Hazzard, W. R., Bierman, E. L. & Motulsky, A. G. Hyperlipidemia in coronary heart disease. II. Genetic analysis of lipid levels in 176 families and delineation of a new inherited disorder, combined hyperlipidemia. J. Clin. Invest. 52, 1544-1568 (1973).
-
(1973)
J. Clin. Invest.
, vol.52
, pp. 1544-1568
-
-
Goldstein, J.L.1
Schrott, H.G.2
Hazzard, W.R.3
Bierman, E.L.4
Motulsky, A.G.5
-
2
-
-
0035436475
-
How should FCHL be defined and how should we think about its metabolic bases?
-
Sniderman, A. D., Ribalta, J. & Castro Cabezas, M. How should FCHL be defined and how should we think about its metabolic bases? Nutr. Metab. Cardiovasc. Dis. 11, 259-273 (2001). (Pubitemid 33686216)
-
(2001)
Nutrition, Metabolism and Cardiovascular Diseases
, vol.11
, Issue.4
, pp. 259-273
-
-
Sniderman, A.D.1
Ribalta, J.2
Castro Cabezas, M.3
-
3
-
-
0038108651
-
Small, dense LDL and elevated apolipoprotein B are the common characteristics for the three major lipid phenotypes of familial combined hyperlipidemia
-
DOI 10.1161/01.ATV.0000077220.44620.9B
-
Ayyobi, A. F. et al. Small, dense LDL and elevated apolipoprotein B are the common characteristics for the three major lipid phenotypes of familial combined hyperlipidemia. Arterioscler. Thromb. Vasc. Biol. 23, 1289-1294 (2003). (Pubitemid 36871286)
-
(2003)
Arteriosclerosis, Thrombosis, and Vascular Biology
, vol.23
, Issue.7
, pp. 1289-1294
-
-
Ayyobi, A.F.1
McGladdery, S.H.2
McNeely, M.J.3
Austin, M.A.4
Motulsky, A.G.5
Brunzell, J.D.6
-
4
-
-
0036159488
-
Diagnosis of familial combined hyperlipidemia based on lipid phenotype expression in 32 families: Results of a 5-year follow-up study
-
DOI 10.1161/hq0202.104059
-
Veerkamp, M. J. et al. Diagnosis of familial combined hyperlipidemia based on lipid phenotype expression in 32 families: results of a 5-year follow-up study. Arterioscler. Thromb. Vasc. Biol. 22, 274-282 (2002). (Pubitemid 34127039)
-
(2002)
Arteriosclerosis, Thrombosis, and Vascular Biology
, vol.22
, Issue.2
, pp. 274-282
-
-
Veerkamp, M.J.1
De Graaf, J.2
Bredie, S.J.H.3
Hendriks, J.C.M.4
Demacker, P.N.M.5
Stalenhoef, A.F.H.6
-
5
-
-
0028172750
-
Genetic predictors of FCHL in four large pedigrees. Influence of ApoB level major locus predicted genotype and LDL subclass phenotype
-
Jarvik, G. P. et al. Genetic predictors of FCHL in four large pedigrees. Influence of ApoB level major locus predicted genotype and LDL subclass phenotype. Arterioscler. Thromb. Vasc. Biol. 14, 1687-1694 (1994).
-
(1994)
Arterioscler. Thromb. Vasc. Biol.
, vol.14
, pp. 1687-1694
-
-
Jarvik, G.P.1
-
6
-
-
78650307216
-
Novel drugs in familial combined hyperlipidemia: Lessons from type 2 diabetes mellitus
-
Brouwers, M. C. et al. Novel drugs in familial combined hyperlipidemia: lessons from type 2 diabetes mellitus. Curr. Opin. Lipidol. 21, 530-538 (2010).
-
(2010)
Curr. Opin. Lipidol.
, vol.21
, pp. 530-538
-
-
Brouwers, M.C.1
-
7
-
-
23244439806
-
Complex trait locus linkage mapping in atherosclerosis: Time to take a step back before moving forward?
-
DOI 10.1161/01.ATV.0000173307.25652.89
-
Pollex, R. L. & Hegele, R. A. Complex trait locus linkage mapping in atherosclerosis: time to take a step back before moving forward? Arterioscler Thromb. Vasc Biol. 25, 1541-1544 (2005). (Pubitemid 41098919)
-
(2005)
Arteriosclerosis, Thrombosis, and Vascular Biology
, vol.25
, Issue.8
, pp. 1541-1544
-
-
Pollex, R.L.1
Hegele, R.A.2
-
8
-
-
18544385510
-
Positional cloning of the combined hyperlipidemia gene Hyplip1
-
Bodnar, J. S. et al. Positional cloning of the combined hyperlipidemia gene Hyplip1. Nat. Genet. 30, 110-116 (2002).
-
(2002)
Nat. Genet.
, vol.30
, pp. 110-116
-
-
Bodnar, J.S.1
-
9
-
-
34247233324
-
High frequency of a retinoid X receptor γ gene variant in familial combined hyperlipidemia that associates with atherogenic dyslipidemia
-
DOI 10.1161/01.ATV.0000258945.76141.8a
-
Nohara, A. et al. High frequency of a retinoid X receptor gamma gene variant in familial combined hyperlipidemia that associates with atherogenic dyslipidemia. Arterioscler. Thromb. Vasc. Biol. 27, 923-928 (2007). (Pubitemid 46606726)
-
(2007)
Arteriosclerosis, Thrombosis, and Vascular Biology
, vol.27
, Issue.4
, pp. 923-928
-
-
Nohara, A.1
Kawashiri, M.-A.2
Claudel, T.3
Mizuno, M.4
Tsuchida, M.5
Takata, M.6
Katsuda, S.7
Miwa, K.8
Inazu, A.9
Kuipers, F.10
Kobayashi, J.11
Koizumi, J.12
Yamagishi, M.13
Mabuchi, H.14
-
10
-
-
0037291864
-
Two novel single nucleotide polymorphisms in the promoter of the Cellular Retinoic Acid Binding Protein II gene (CRABP-II)
-
DOI 10.1016/S0890-8508(02)00110-X
-
Salazar, J. et al. Two novel single nucleotide polymorphisms in the promoter of the cellular retinoic acid binding protein II gene (CRABP-II). Mol. Cell Probes. 17, 21-23 (2003). (Pubitemid 36287306)
-
(2003)
Molecular and Cellular Probes
, vol.17
, Issue.1
, pp. 21-23
-
-
Salazar, J.1
Ferre, R.2
Vallve, J.-C.3
Pocovi, M.4
Cabezas, M.C.5
Masana, L.6
Ribalta, J.7
-
11
-
-
69849116067
-
The ATF6-Met[67]Val substitution is associated with increased plasma cholesterol levels
-
Meex, S. J. et al. The ATF6-Met[67]Val substitution is associated with increased plasma cholesterol levels. Arterioscler. Thromb. Vasc. Biol. 29, 1322-1327 (2009).
-
(2009)
Arterioscler. Thromb. Vasc. Biol.
, vol.29
, pp. 1322-1327
-
-
Meex, S.J.1
-
12
-
-
12144287541
-
Familial combined hyperlipidemia is associated with upstream transcription factor 1 (USF1)
-
DOI 10.1038/ng1320
-
Pajukanta, P. et al. Familial combined hyperlipidemia is associated with upstream transcription factor 1 (USF1). Nat. Genet. 36, 371-376 (2004). (Pubitemid 38437259)
-
(2004)
Nature Genetics
, vol.36
, Issue.4
, pp. 371-376
-
-
Pajukanta, P.1
Lilja, H.E.2
Sinsheimer, J.S.3
Cantor, R.M.4
Lusis, A.J.5
Gentile, M.6
Duan, X.J.7
Soro-Paavonen, A.8
Naukkarinen, J.9
Saarela, J.10
Laakso, M.11
Ehnholm, C.12
Taskinen, M.-R.13
Peltonen, L.14
-
13
-
-
24144455710
-
Upstream stimulatory factor 1 associated with familial combined hyperlipidemia, LDL cholesterol, and triglycerides
-
DOI 10.1007/s00439-005-1340-x
-
Coon, H. et al. Upstream stimulatory factor 1 associated with familial combined hyperlipidemia, LDL cholesterol, and triglycerides. Hum. Genet. 117, 444-451 (2005). (Pubitemid 41236365)
-
(2005)
Human Genetics
, vol.117
, Issue.5
, pp. 444-451
-
-
Coon, H.1
Xin, Y.2
Hopkins, P.N.3
Cawthon, R.M.4
Hasstedt, S.J.5
Hunt, S.C.6
-
14
-
-
24144435303
-
Familial combined hyperlipidemia in mexicans: Association with upstream transcription factor 1 and linkage on chromosome 16q24.1
-
DOI 10.1161/01.ATV.0000175297.37214.a0
-
Huertas-Vazquez, A. et al. Familial combined hyperlipidemia in Mexicans: association with upstream transcription factor 1 and linkage on chromosome 16q24.1. Arterioscler. Thromb. Vasc. Biol. 25, 1985-1991 (2005). (Pubitemid 41243473)
-
(2005)
Arteriosclerosis, Thrombosis, and Vascular Biology
, vol.25
, Issue.9
, pp. 1985-1991
-
-
Huertas-Vazquez, A.1
Aguilar-Salinas, C.2
Lusis, A.J.3
Cantor, R.M.4
Canizales-Quinteros, S.5
Lee, J.C.6
Mariana-Nunez, L.7
Roopa-Metha8
Riba-Ramirez, L.9
Jokiaho, A.10
Tusie-Luna, T.11
Pajukanta, P.12
-
15
-
-
2342530962
-
TXNIP gene not associated with familial combined hyperlipidemia in the NHLBI Family Heart Study
-
DOI 10.1016/j.atherosclerosis.2004.02.004, PII S0021915004000929
-
Coon, H. et al. TXNIP gene not associated with familial combined hyperlipidemia in the NHLBI Family Heart Study. Atherosclerosis 174, 357-362 (2004). (Pubitemid 38597094)
-
(2004)
Atherosclerosis
, vol.174
, Issue.2
, pp. 357-362
-
-
Coon, H.1
Singh, N.2
Dunn, D.3
Eckfeldt, J.H.4
Province, M.A.5
Hopkins, P.N.6
Weiss, R.7
Hunt, S.C.8
Leppert, M.F.9
-
16
-
-
33646077914
-
Can we exclude the TXNIP gene as a candidate gene for familial combined hyperlipidemia?
-
van der Vleuten, G. M. et al. Can we exclude the TXNIP gene as a candidate gene for familial combined hyperlipidemia? Am. J. Med. Genet. A 140, 1010-1012 (2006).
-
(2006)
Am. J. Med. Genet. A
, vol.140
, pp. 1010-1012
-
-
Van Der Vleuten, G.M.1
-
17
-
-
4344563211
-
Thioredoxin interacting protein in Dutch families with familial combined hyperlipidemia
-
van der Vleuten, G. M. et al. Thioredoxin interacting protein in Dutch families with familial combined hyperlipidemia. Am. J. Med. Genet. A 130A, 73-75 (2004). (Pubitemid 39121563)
-
(2004)
American Journal of Medical Genetics
, vol.130
, Issue.1
, pp. 73-75
-
-
Van Der Vleuten, G.M.1
Hijmans, A.2
Kluijtmans, L.A.J.3
Blom, H.J.4
Stalenhoef, A.F.H.5
De Graaf, J.6
-
18
-
-
58149161560
-
Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts
-
Aulchenko, Y. S. et al. Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts. Nat. Genet. 41, 47-55 (2009).
-
(2009)
Nat. Genet.
, vol.41
, pp. 47-55
-
-
Aulchenko, Y.S.1
-
19
-
-
58149163149
-
Common variants at 30 loci contribute to polygenic dyslipidemia
-
Kathiresan, S. et al. Common variants at 30 loci contribute to polygenic dyslipidemia. Nat. Genet. 41, 56-65 (2009).
-
(2009)
Nat. Genet.
, vol.41
, pp. 56-65
-
-
Kathiresan, S.1
-
20
-
-
77955505564
-
Biological, clinical and population relevance of 95 loci for blood lipids
-
Teslovich, T. M. et al. Biological, clinical and population relevance of 95 loci for blood lipids. Nature 466, 707-713 (2010).
-
(2010)
Nature
, vol.466
, pp. 707-713
-
-
Teslovich, T.M.1
-
21
-
-
77952533413
-
Investigation of variants identified in caucasian genome-wide association studies for plasma high-density lipoprotein cholesterol and triglycerides levels in Mexican dyslipidemic study samples
-
Weissglas-Volkov, D. et al. Investigation of variants identified in caucasian genome-wide association studies for plasma high-density lipoprotein cholesterol and triglycerides levels in Mexican dyslipidemic study samples. Circ. Cardiovasc. Genet. 3, 31-38 (2010).
-
(2010)
Circ. Cardiovasc. Genet.
, vol.3
, pp. 31-38
-
-
Weissglas-Volkov, D.1
-
22
-
-
0028926192
-
Impaired activation of adipocyte lipolysis in familial combined hyperlipidemia
-
Reynisdottir, S., Eriksson, M., Angelin, B. & Arner, P. Impaired activation of adipocyte lipolysis in familial combined hyperlipidemia. J. Clin. Invest. 95, 2161-2169 (1995).
-
(1995)
J. Clin. Invest.
, vol.95
, pp. 2161-2169
-
-
Reynisdottir, S.1
Eriksson, M.2
Angelin, B.3
Arner, P.4
-
23
-
-
80053927990
-
Dynamics of human adipose lipid turnover in health and metabolic disease
-
Arner, P. et al. Dynamics of human adipose lipid turnover in health and metabolic disease. Nature 478, 110-113 (2011).
-
(2011)
Nature
, vol.478
, pp. 110-113
-
-
Arner, P.1
-
24
-
-
0035059178
-
The hormone sensitive lipase gene in familial combined hyperlipidemia and insulin resistance
-
DOI 10.1046/j.1365-2362.2001.00813.x
-
Pihlajamäki, J. et al. The hormone sensitive lipase gene in familial combined hyperlipidemia and insulin resistance. Eur. J. Clin. Invest. 31, 302-308 (2001). (Pubitemid 32328530)
-
(2001)
European Journal of Clinical Investigation
, vol.31
, Issue.4
, pp. 302-308
-
-
Pihlajamaki, J.1
Valve, R.2
Karjalainen, L.3
Karhapaa, P.4
Vauhkonen, I.5
Laakso, M.6
-
25
-
-
0034496563
-
Reduced hormone-sensitive lipase activity is not a major metabolic defect in Finnish FCHL families
-
DOI 10.1016/S0021-9150(00)00410-X, PII S002191500000410X
-
Ylitalo, K. et al. Reduced hormone-sensitive lipase activity is not a major metabolic defect in Finnish FCHL families. Atherosclerosis 153, 373-381 (2000). (Pubitemid 32120336)
-
(2000)
Atherosclerosis
, vol.153
, Issue.2
, pp. 373-381
-
-
Ylitalo, K.1
Large, V.2
Pajukanta, P.3
Reynisdottir, S.4
Porkka, K.V.K.5
Vakkilainen, J.6
Nuotio, I.7
Taskinen, M.-R.8
Arner, P.9
-
26
-
-
16944363110
-
No evidence of linkage between familial combined hyperlipidemia and genes encoding lipolytic enzymes in Finnish families
-
Pajukanta, P. et al. No evidence of linkage between familial combined hyperlipidemia and genes encoding lipolytic enzymes in Finnish families. Arterioscler. Thromb. Vasc. Biol. 17, 841-850 (1997). (Pubitemid 27209260)
-
(1997)
Arteriosclerosis, Thrombosis, and Vascular Biology
, vol.17
, Issue.5
, pp. 841-850
-
-
Pajukanta, P.1
Porkka, K.V.K.2
Antikainen, M.3
Taskinen, M.-R.4
Perola, M.5
Murtomaki-Repo, S.6
Ehnholm, S.7
Nuotio, I.8
Suurinkeroinen, L.9
Lahdenkari, A.-T.10
Syvaen, A.-C.11
Viikari, J.S.A.12
Ehnholm, C.13
Peltonen, L.14
-
27
-
-
8844226709
-
Fat mobilization in adipose tissue is promoted by adipose triglyceride lipase
-
DOI 10.1126/science.1100747
-
Zimmermann, R. et al. Fat mobilization in adipose tissue is promoted by adipose triglyceride lipase. Science 306, 1383-1386 (2004). (Pubitemid 39532517)
-
(2004)
Science
, vol.306
, Issue.5700
, pp. 1383-1386
-
-
Zimmermann, R.1
Strauss, J.G.2
Haemmerle, G.3
Schoiswohl, G.4
Birner-Gruenberger, R.5
Riederer, M.6
Lass, A.7
Neuberger, G.8
Eisenhaber, F.9
Hermetter, A.10
Zechner, R.11
-
28
-
-
77958502859
-
Genetic variants in adipose triglyceride lipase influence lipid levels in familial combined hyperlipidemia
-
Nanni, L. et al. Genetic variants in adipose triglyceride lipase influence lipid levels in familial combined hyperlipidemia. Atherosclerosis 213, 206-211 (2010).
-
(2010)
Atherosclerosis
, vol.213
, pp. 206-211
-
-
Nanni, L.1
-
29
-
-
24344482858
-
Upstream transcription factor-1 gene polymorphism is associated with increased adipocyte lipolysis
-
DOI 10.1210/jc.2005-0399
-
Hoffstedt, J., Rydén, M., Wahrenberg, H., van Harmelen, V. & Arner, P. Upstream transcription factor-1 gene polymorphism is associated with increased adipocyte lipolysis. J. Clin. Endocrinol. Metab. 90, 5356-5360 (2005). (Pubitemid 41262301)
-
(2005)
Journal of Clinical Endocrinology and Metabolism
, vol.90
, Issue.9
, pp. 5356-5360
-
-
Hoffstedt, J.1
Ryden, M.2
Wahrenberg, H.3
Van Harmelen, V.4
Arner, P.5
-
30
-
-
33745953646
-
Identification of a Novel C5L2 variant (S323I) in a French Canadian family with familial combined hyperlipemia
-
DOI 10.1161/01.ATV.0000222907.72985.0b, PII 0004360520060700000034
-
Marcil, M. et al. Identification of a novel C5L2 variant (S323I) in a French Canadian family with familial combined hyperlipemia. Arterioscler. Thromb. Vasc. Biol. 26, 1619-1625 (2006). (Pubitemid 44288992)
-
(2006)
Arteriosclerosis, Thrombosis, and Vascular Biology
, vol.26
, Issue.7
, pp. 1619-1625
-
-
Marcil, M.1
Vu, H.2
Cui, W.3
Dastani, Z.4
Engert, J.C.5
Gaudet, D.6
Castro-Cabezas, M.7
Sniderman, A.D.8
Genest, J.9
Cianflone, K.10
-
31
-
-
33845567067
-
Heritability and genetic loci of fatty liver in familial combined hyperlipidemia
-
DOI 10.1194/jlr.M600312-JLR200
-
Brouwers, M. C. et al. Heritability and genetic loci of fatty liver in familial combined hyperlipidemia. J. Lipid Res. 47, 2799-2807 (2006). (Pubitemid 44936093)
-
(2006)
Journal of Lipid Research
, vol.47
, Issue.12
, pp. 2799-2807
-
-
Brouwers, M.C.G.J.1
-
32
-
-
0027322479
-
Stable isotopes show a direct relation between VLDL apoB overproduction and serum triglyceride levels and indicate a metabolically and biochemically coherent basis for familial combined hyperlipidemia
-
Venkatesan, S., Cullen, P., Pacy, P., Halliday, D. & Scott, J. Stable isotopes show a direct relation between VLDL apoB overproduction and serum triglyceride levels and indicate a metabolically and biochemically coherent basis for familial combined hyperlipidemia. Arterioscler. Thromb. 13, 1110-1118 (1993). (Pubitemid 23195814)
-
(1993)
Arteriosclerosis and Thrombosis
, vol.13
, Issue.7
, pp. 1110-1118
-
-
Venkatesan, S.1
Cullen, P.2
Pacy, P.3
Halliday, D.4
Scott, J.5
-
33
-
-
33644827082
-
Overproduction of large VLDL particles is driven by increased liver fat content in man
-
DOI 10.1007/s00125-005-0125-z
-
Adiels, M. et al. Overproduction of large VLDL particles is driven by increased liver fat content in man. Diabetologia 49, 755-765 (2006). (Pubitemid 43357551)
-
(2006)
Diabetologia
, vol.49
, Issue.4
, pp. 755-765
-
-
Adiels, M.1
Taskinen, M.-R.2
Packard, C.3
Caslake, M.J.4
Soro-Paavonen, A.5
Westerbacka, J.6
Vehkavaara, S.7
Hakkinen, A.8
Olofsson, S.-O.9
Yki-Jarvinen, H.10
Boren, J.11
-
34
-
-
38649111018
-
Alterations in Adipose Tissue and Hepatic Lipid Kinetics in Obese Men and Women With Nonalcoholic Fatty Liver Disease
-
DOI 10.1053/j.gastro.2007.11.038, PII S0016508507021154
-
Fabbrini, E. et al. Alterations in adipose tissue and hepatic lipid kinetics in obese men and women with nonalcoholic fatty liver disease. Gastroenterology 134, 424-431 (2008). (Pubitemid 351173050)
-
(2008)
Gastroenterology
, vol.134
, Issue.2
, pp. 424-431
-
-
Fabbrini, E.1
Mohammed, B.S.2
Magkos, F.3
Korenblat, K.M.4
Patterson, B.W.5
Klein, S.6
-
35
-
-
18244382304
-
Sources of fatty acids stored in liver and secreted via lipoproteins in patients with nonalcoholic fatty liver disease
-
DOI 10.1172/JCI200523621
-
Donnelly, K. L. et al. Sources of fatty acids stored in liver and secreted via lipoproteins in patients with nonalcoholic fatty liver disease. J. Clin. Invest. 115, 1343-1351 (2005). (Pubitemid 40629054)
-
(2005)
Journal of Clinical Investigation
, vol.115
, Issue.5
, pp. 1343-1351
-
-
Donnelly, K.L.1
Smith, C.I.2
Schwarzenberg, S.J.3
Jessurun, J.4
Boldt, M.D.5
Parks, E.J.6
-
36
-
-
70349980881
-
The P446L variant in GCKR associated with fasting plasma glucose and triglyceride levels exerts its effect through increased glucokinase activity in liver
-
Beer, N. L. et al. The P446L variant in GCKR associated with fasting plasma glucose and triglyceride levels exerts its effect through increased glucokinase activity in liver. Hum. Mol. Genet. 18, 4081-4088 (2009).
-
(2009)
Hum. Mol. Genet.
, vol.18
, pp. 4081-4088
-
-
Beer, N.L.1
-
37
-
-
54249088172
-
Common missense variant in the glucokinase regulatory protein gene is associated with increased plasma triglyceride and C-reactive protein but lower fasting glucose concentrations
-
Orho-Melander, M. et al. Common missense variant in the glucokinase regulatory protein gene is associated with increased plasma triglyceride and C-reactive protein but lower fasting glucose concentrations. Diabetes 57, 3112-3121 (2008).
-
(2008)
Diabetes
, vol.57
, pp. 3112-3121
-
-
Orho-Melander, M.1
-
38
-
-
26244431875
-
The linkage and association of the gene encoding upstream stimulatory factor 1 with type 2 diabetes and metabolic syndrome in the Chinese population
-
DOI 10.1007/s00125-005-1914-0
-
Ng, M. C. et al. The linkage and association of the gene encoding upstream stimulatory factor 1 with type 2 diabetes and metabolic syndrome in the Chinese population. Diabetologia 48, 2018-2024 (2005). (Pubitemid 41416912)
-
(2005)
Diabetologia
, vol.48
, Issue.10
, pp. 2018-2024
-
-
Ng, M.C.Y.1
Miyake, K.2
So, W.Y.3
Poon, E.W.M.4
Lam, V.K.L.5
Li, J.K.Y.6
Cox, N.J.7
Bell, G.I.8
Chan, J.C.N.9
-
39
-
-
33750592176
-
Variation within the gene encoding the upstream stimulatory factor 1 does not influence susceptibility to type 2 diabetes in samples from populations with replicated evidence of linkage to chromosome 1q
-
DOI 10.2337/db06-0088
-
Zeggini, E. et al. Variation within the gene encoding the upstream stimulatory factor 1 does not influence susceptibility to type 2 diabetes in samples from populations with replicated evidence of linkage to chromosome 1q. Diabetes 55, 2541-2548 (2006). (Pubitemid 44871154)
-
(2006)
Diabetes
, vol.55
, Issue.9
, pp. 2541-2548
-
-
Zeggini, E.1
Damcott, C.M.2
Hanson, R.L.3
Karim, M.A.4
Rayner, N.W.5
Groves, C.J.6
Baier, L.J.7
Hale, T.C.8
Hattersley, A.T.9
Hitman, G.A.10
Hunt, S.E.11
Knowler, W.C.12
Mitchell, B.D.13
Ng, M.C.Y.14
O'Connel, J.R.15
Pollin, T.I.16
Vaxillaire, M.17
Walker, M.18
Wang, X.19
Whittaker, P.20
Xiang, K.21
Jia, W.22
Chan, J.C.N.23
Froguel, P.24
Deloukas, P.25
Shuldiner, A.R.26
Elbein, S.C.27
McCarthy, M.I.28
more..
-
40
-
-
44949263784
-
Upstream transcription factor 1 (USF1) in risk of type 2 diabetes: Association study in 2000 Dutch Caucasians
-
Meex, S. J. et al. Upstream transcription factor 1 (USF1) in risk of type 2 diabetes: association study in 2000 Dutch Caucasians. Mol. Genet. Metab. 94, 352-355 (2008).
-
(2008)
Mol. Genet. Metab.
, vol.94
, pp. 352-355
-
-
Meex, S.J.1
-
41
-
-
0033593229
-
Essential role in vivo of upstream stimulatory factors for a normal dietary response of the fatty acid synthase gene in the liver
-
Casado, M., Vallet, V. S., Kahn, A. & Vaulont, S. Essential role in vivo of upstream stimulatory factors for a normal dietary response of the fatty acid synthase gene in the liver. J. Biol. Chem. 274, 2009-2013 (1999).
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 2009-2013
-
-
Casado, M.1
Vallet, V.S.2
Kahn, A.3
Vaulont, S.4
-
42
-
-
0032143525
-
Identification of upstream stimulatory factor as transcriptional activator of the liver promoter of the glucokinase gene
-
Iynedjian, P. B. Identification of upstream stimulatory factor as transcriptional activator of the liver promoter of the glucokinase gene. Biochem. J. 333 (Pt 3), 705-712 (1998). (Pubitemid 28398539)
-
(1998)
Biochemical Journal
, vol.333
, Issue.3
, pp. 705-712
-
-
Iynedjian, P.B.1
-
43
-
-
0031458498
-
Lipoprotein heterogeneity and apolipoprotein B metabolism
-
Packard, C. J. & Shepherd, J. Lipoprotein heterogeneity and apolipoprotein B metabolism. Arterioscler. Thromb. Vasc. Biol. 17, 3542-3556 (1997). (Pubitemid 28028567)
-
(1997)
Arteriosclerosis, Thrombosis, and Vascular Biology
, vol.17
, Issue.12
, pp. 3542-3556
-
-
Packard, C.J.1
Shepherd, J.2
-
44
-
-
0036186397
-
Postprandial changes of apoB-100 and apoB-48 in TG rich lipoproteins in familial combined hyperlipidemia
-
Verseyden, C., Meijssen, S. & Castro Cabezas, M. Postprandial changes of apoB-100 and apoB-48 in TG rich lipoproteins in familial combined hyperlipidemia. J. Lipid Res. 43, 274-280 (2002). (Pubitemid 34184014)
-
(2002)
Journal of Lipid Research
, vol.43
, Issue.2
, pp. 274-280
-
-
Verseyden, C.1
Meijssen, S.2
Cabezas, M.C.3
-
45
-
-
0026731011
-
Familial combined hyperlipidemia and abnormal lipoprotein lipase
-
Babirak, S. P., Brown, B. G. & Brunzell, J. D. Familial combined hyperlipidemia and abnormal lipoprotein lipase. Arterioscler. Thromb. 12, 1176-1183 (1992).
-
(1992)
Arterioscler. Thromb.
, vol.12
, pp. 1176-1183
-
-
Babirak, S.P.1
Brown, B.G.2
Brunzell, J.D.3
-
46
-
-
64649106575
-
Small and dense LDL in familial combined hyperlipidemia and N291S polymorphism of the lipoprotein lipase gene
-
López-Ruiz, A. et al. Small and dense LDL in familial combined hyperlipidemia and N291S polymorphism of the lipoprotein lipase gene. Lipids Health Dis. 8, 12 (2009).
-
(2009)
Lipids Health Dis.
, vol.8
, pp. 12
-
-
López-Ruiz, A.1
-
47
-
-
0036799685
-
3-adrenergic receptor, and the intestinal fatty acid binding protein-2 genes, influence the lipid phenotypic expression in familial combined hyperlipidemia
-
DOI 10.1053/meta.2002.35197
-
Campagna, F. et al. Common variants in the lipoprotein lipase gene, but not those in the insulin receptor substrate-1, the β3-adrenergic receptor, and the intestinal fatty acid binding protein-2 genes, influence the lipid phenotypic expression in familial combined hyperlipidemia. Metabolism 51, 1298-1305 (2002). (Pubitemid 35174152)
-
(2002)
Metabolism: Clinical and Experimental
, vol.51
, Issue.10
, pp. 1298-1305
-
-
Campagna, F.1
Montali, A.2
Baroni, M.G.3
Maria, A.T.4
Ricci, G.5
Antonini, R.6
Verna, R.7
Arca, M.8
-
48
-
-
0030452127
-
Regulatory mutations in the human lipoprotein lipase gene in patients with familial combined hyperlipidemia and coronary artery disease
-
Yang, W. S. et al. Regulatory mutations in the human lipoprotein lipase gene in patients with familial combined hyperlipidemia and coronary artery disease. J. Lipid Res. 37, 2627-2637 (1996).
-
(1996)
J. Lipid Res.
, vol.37
, pp. 2627-2637
-
-
Yang, W.S.1
-
49
-
-
0029142759
-
A frequently occurring mutation in the lipoprotein lipase gene (Asn291Ser) contributes to the expression of familial combined hyperlipidemia
-
Reymer, P. W. et al. A frequently occurring mutation in the lipoprotein lipase gene (Asn291Ser) contributes to the expression of familial combined hyperlipidemia. Hum. Mol. Genet. 4, 1543-1549 (1995).
-
(1995)
Hum. Mol. Genet.
, vol.4
, pp. 1543-1549
-
-
Reymer, P.W.1
-
50
-
-
0029045344
-
A mutation in the promoter of the lipoprotein lipase (LPL) gene in a patient with familial combined hyperlipidemia and low LPL activity
-
Yang, W. S., Nevin, D. N., Peng, R., Brunzell, J. D. & Deeb, S. S. A mutation in the promoter of the lipoprotein lipase (LPL) gene in a patient with familial combined hyperlipidemia and low LPL activity. Proc. Natl Acad. Sci. USA 92, 4462-4466 (1995).
-
(1995)
Proc. Natl Acad. Sci. USA
, vol.92
, pp. 4462-4466
-
-
Yang, W.S.1
Nevin, D.N.2
Peng, R.3
Brunzell, J.D.4
Deeb, S.S.5
-
51
-
-
0028179511
-
The LPL gene in individuals with familial combined hyperlipidemia and decreased LPL activity
-
Nevin, D. N., Brunzell, J. D. & Deeb, S. S. The LPL gene in individuals with familial combined hyperlipidemia and decreased LPL activity. Arterioscler. Thromb. 14, 869-873 (1994).
-
(1994)
Arterioscler. Thromb.
, vol.14
, pp. 869-873
-
-
Nevin, D.N.1
Brunzell, J.D.2
Deeb, S.S.3
-
52
-
-
0028167760
-
Analysis of DNA changes in the LPL gene in patients with familial combined hyperlipidemia
-
Gagne, E., Genest, J. Jr, Zhang, H., Clarke, L. A. & Hayden, M. R. Analysis of DNA changes in the LPL gene in patients with familial combined hyperlipidemia. Arterioscler. Thromb. 14, 1250-1257 (1994).
-
(1994)
Arterioscler. Thromb.
, vol.14
, pp. 1250-1257
-
-
Gagne, E.1
Genest Jr., J.2
Zhang, H.3
Clarke, L.A.4
Hayden, M.R.5
-
53
-
-
17444444680
-
Gender-related association between the -93T →Gg/D9N haplotype of the lipoprotein lipase gene and elevated lipid levels in familial combined hyperlipidemia
-
DOI 10.1016/S0021-9150(98)00007-0, PII S0021915098000070
-
Hoffer, M. J. et al. Gender-related association between the-93T->G/D9N haplotype of the lipoprotein lipase gene and elevated lipid levels in familial combined hyperlipidemia. Atherosclerosis 138, 91-99 (1998). (Pubitemid 28255157)
-
(1998)
Atherosclerosis
, vol.138
, Issue.1
, pp. 91-99
-
-
Hoffer, M.J.V.1
Bredie, S.J.H.2
Snieder, H.3
Reymer, P.W.A.4
Demacker, P.N.M.5
Havekes, L.M.6
Boomsma, D.I.7
Stalenhoef, A.F.H.8
Frants, R.R.9
Kastelein, J.J.P.10
-
54
-
-
0029768936
-
Lipoprotein lipase gene mutations D9N and N291S in four pedigrees with familial combined hyperlipidaemia
-
de Bruin, T. W. et al. Lipoprotein lipase gene mutations D9N and N291S in four pedigrees with familial combined hyperlipidaemia. Eur. J. Clin. Invest. 26, 631-639 (1996). (Pubitemid 26273710)
-
(1996)
European Journal of Clinical Investigation
, vol.26
, Issue.8
, pp. 631-639
-
-
De Bruin, T.W.A.1
Mailly, F.2
Van Barlingen, H.H.J.J.3
Fisher, R.4
Castro Cabezas, M.5
Talmud, P.6
Dallinga-Thie, G.M.7
Humphries, S.E.8
-
55
-
-
0042206697
-
Postprandial triglyceride levels in familial combined hyperlipidemia. The role of apolipoprotein E and lipoprotein lipase polymorphisms
-
DOI 10.1016/S0955-2863(03)00061-5
-
Reiber, I. et al. Postprandial triglyceride levels in familial combined hyperlipidemia. The role of apolipoprotein E and lipoprotein lipase polymorphisms. J. Nutr. Biochem. 14, 394-400 (2003). (Pubitemid 36952659)
-
(2003)
Journal of Nutritional Biochemistry
, vol.14
, Issue.7
, pp. 394-400
-
-
Reiber, I.1
Mezo, I.2
Kalina, A.3
Palos, G.4
Romics, L.5
Csaszar, A.6
-
56
-
-
0033853598
-
The V73M mutation in the hepatic lipase gene is associated with elevated cholesterol levels in four Dutch pedigrees with familial combined hyperlipidemia
-
DOI 10.1016/S0021-9150(99)00428-1, PII S0021915099004281
-
Hoffer, M. J. et al. The V73M mutation in the hepatic lipase gene is associated with elevated cholesterol levels in four Dutch pedigrees with familial combined hyperlipidemia. Atherosclerosis 151, 443-450 (2000). (Pubitemid 30618761)
-
(2000)
Atherosclerosis
, vol.151
, Issue.2
, pp. 443-450
-
-
Hoffer, M.J.V.1
Snieder, H.2
Bredie, S.J.H.3
Demacker, P.N.M.4
Kastelein, J.J.P.5
Frants, R.R.6
Stalenhoef, A.F.H.7
-
57
-
-
0032709520
-
Mutations of the human hepatic lipase gene in patients with combined hypertriglyceridemia/hyperalphalipoproteinemia and in patients with familial combined hyperlipidemia
-
Gehrisch, S. et al. Mutations of the human hepatic lipase gene in patients with combined hypertriglyceridemia/hyperalphalipoproteinemia and in patients with familial combined hyperlipidemia. J. Mol. Med. (Berl.) 77, 728-734 (1999).
-
(1999)
J. Mol. Med. (Berl.
, vol.77
, pp. 728-734
-
-
Gehrisch, S.1
-
58
-
-
9144257873
-
Linkage and Association between Distinct Variants of the APOA1/C3/A4/A5 Gene Cluster and Familial Combined Hyperlipidemia
-
DOI 10.1161/01.ATV.0000099881.83261.D4
-
Eichenbaum-Voline, S. et al. Linkage and association between distinct variants of the APOA1/C3/A4/A5 gene cluster and familial combined hyperlipidemia. Arterioscler. Thromb. Vasc. Biol. 24, 167-174 (2004). (Pubitemid 38082429)
-
(2004)
Arteriosclerosis, Thrombosis, and Vascular Biology
, vol.24
, Issue.1
, pp. 167-174
-
-
Eichenbaum-Voline, S.1
Olivier, M.2
Jones, E.L.3
Naoumova, R.P.4
Jones, B.5
Gau, B.6
Patel, H.N.7
Seed, M.8
Betteridge, D.J.9
Galton, D.J.10
Rubin, E.M.11
Scott, J.12
Shoulders, C.C.13
Pennacchio, L.A.14
-
59
-
-
0035740398
-
Two newly identified SNPs in the apo AI-CIII intergenic region are strongly associated with familial combined hyperlipidaemia
-
DOI 10.1046/j.1365-2362.2001.00888.x
-
Groenendijk, M., Cantor, R. M., Funke, H. & Dallinga-Thie, G. M. Two newly identified SNPs in the APO AI-CIII intergenic region are strongly associated with familial combined hyperlipidaemia. Eur. J. Clin. Invest. 31, 852-859 (2001). (Pubitemid 34592084)
-
(2001)
European Journal of Clinical Investigation
, vol.31
, Issue.10
, pp. 852-859
-
-
Groenendijk, M.1
Cantor, R.M.2
Funke, H.3
Dallinga-Thie, G.M.4
-
60
-
-
0034802431
-
Two polymorphisms in the apo A-IV gene and familial combined hyperlipidemia
-
DOI 10.1016/S0021-9150(01)00460-9, PII S0021915001004609
-
Groenendijk, M., De Bruin, T. W. & Dallinga-Thie, G. M. Two polymorphisms in the apo A-IV gene and familial combined hyperlipidemia. Atherosclerosis 158, 369-376 (2001). (Pubitemid 32913646)
-
(2001)
Atherosclerosis
, vol.158
, Issue.2
, pp. 369-376
-
-
Groenendijk, M.1
De Bruin, T.W.A.2
Dallinga-Thie, G.M.3
-
61
-
-
0035089565
-
New genetic variants in the apoA-I and apoC-III genes and familial combined hyperlipidemia
-
Groenendijk, M., Cantor, R. M., De Bruin, T. W. & Dallinga-Thie, G. M. New genetic variants in the apoA-I and apoC-III genes and familial combined hyperlipidemia. J. Lipid Res. 42, 188-194 (2001). (Pubitemid 32206829)
-
(2001)
Journal of Lipid Research
, vol.42
, Issue.2
, pp. 188-194
-
-
Groenendijk, M.1
Cantor, R.M.2
De Bruin, T.W.A.3
Dallinga-Thie, G.M.4
-
62
-
-
0032698344
-
Linkage of a candidate gene locus to familial combined hyperlipidemia: Lecithin:cholesterol acyltransferase on 16q
-
Aouizerat, B. E. et al. Linkage of a candidate gene locus to familial combined hyperlipidemia: lecithin:cholesterol acyltransferase on 16q. Arterioscler. Thromb. Vasc. Biol. 19, 2730-2736 (1999). (Pubitemid 29536050)
-
(1999)
Arteriosclerosis, Thrombosis, and Vascular Biology
, vol.19
, Issue.11
, pp. 2730-2736
-
-
Aouizerat, B.E.1
Allayee, H.2
Cantor, R.M.3
Dallinga-Thie, G.M.4
Lanning, C.D.5
De Bruin, T.W.A.6
Lusis, A.J.7
Rotter, J.I.8
-
63
-
-
0023227643
-
DNA polymorphisms in and around the Apo-A1-CIII genes and genetic hyperlipidemias
-
Hayden, M. R. et al. DNA polymorphisms in and around the Apo-A1-CIII genes and genetic hyperlipidemias. Am. J. Hum. Genet. 40, 421-430 (1987). (Pubitemid 17096944)
-
(1987)
American Journal of Human Genetics
, vol.40
, Issue.5
, pp. 421-430
-
-
Hayden, M.R.1
Kirk, H.2
Clark, C.3
-
64
-
-
0030978794
-
A variation in the apolipoprotein C-III gene is associated with an increased number of circulating VLDL and IDL particles in familial combined hyperlipidemia
-
Ribalta, J. et al. A variation in the apolipoprotein C-III gene is associated with an increased number of circulating VLDL and IDL particles in familial combined hyperlipidemia. J. Lipid Res. 38, 1061-1069 (1997). (Pubitemid 27281802)
-
(1997)
Journal of Lipid Research
, vol.38
, Issue.6
, pp. 1061-1069
-
-
Ribalta, J.1
La Ville, A.E.2
Vallve, J.C.3
Humphries, S.4
Turner, P.R.5
Masana, L.6
-
65
-
-
0025970749
-
Familial combined hyperlipidaemia linked to the apolipoprotein AI-CIII-AIV gene cluster on chromosome 11q23-q24
-
Wojciechowski, A. P. et al. Familial combined hyperlipidaemia linked to the apolipoprotein AI-CII-AIV gene cluster on chromosome 11q23-q24. Nature 349, 161-164 (1991). (Pubitemid 21912036)
-
(1991)
Nature
, vol.349
, Issue.6305
, pp. 161-164
-
-
Wojciechowski, A.P.1
Farrall, M.2
Cullen, P.3
Wilson, T.M.E.4
Bayliss, J.D.5
Farren, B.6
Griffin, B.A.7
Caslake, M.J.8
Packard, C.J.9
Shepherd, J.10
Thakker, R.11
Scott, J.12
-
66
-
-
6444229534
-
Contribution of chromosome 1q21-q23 to familial combined hyperlipidemia in Mexican families
-
DOI 10.1046/j.1529-8817.2003.00116.x
-
Huertas-Vázquez, A. et al. Contribution of chromosome 1q21-q23 to familial combined hyperlipidemia in Mexican families. Ann. Hum. Genet. 68, 419-427 (2004). (Pubitemid 39405952)
-
(2004)
Annals of Human Genetics
, vol.68
, Issue.5
, pp. 419-427
-
-
Huertas-Vazquez, A.1
Del Rincon, J.P.2
Canizales-Quinteros, S.3
Riba, L.4
Vega-Hernandez, G.5
Ramirez-Jimenez, S.6
Auron-Gomez, M.7
Gomez-Perez, F.J.8
Aguilar-Salinas, C.A.9
Tusie-Luna, Ma.T.10
-
67
-
-
0031808957
-
Evidence against linkage of familial combined hyperlipidemia to the apolipoprotein AI-CIII-AIV gene complex
-
Wijsman, E. M. et al. Evidence against linkage of familial combined hyperlipidemia to the apolipoprotein AI-CIII-AIV gene complex. Arterioscler. Thromb. Vasc. Biol. 18, 215-226 (1998). (Pubitemid 28277598)
-
(1998)
Arteriosclerosis, Thrombosis, and Vascular Biology
, vol.18
, Issue.2
, pp. 215-226
-
-
Wijsman, E.M.1
Brunzell, J.D.2
Jarvik, G.P.3
Austin, M.A.4
Motulsky, A.G.5
Deeb, S.S.6
-
68
-
-
0029922275
-
Lack of association of the apolipoprotein A-I-C-III-A-IV gene XmnI and SstI polymorphisms and of the lipoprotein lipase gene mutations in familial combined hyperlipoproteinemia in French Canadian subjects
-
Marcil, M. et al. Lack of association of the apolipoprotein A-I-C-III-A-IV gene XmnI and SstI polymorphisms and of the lipoprotein lipase gene mutations in familial combined hyperlipoproteinemia in French Canadian subjects. J. Lipid Res. 37, 309-319 (1996).
-
(1996)
J. Lipid Res.
, vol.37
, pp. 309-319
-
-
Marcil, M.1
-
69
-
-
0028559791
-
Association between genetic variation at the APO AI-CIII-AIV gene cluster and familial combined hyperlipidaemia
-
Xu, C. F. et al. Association between genetic variation at the APO AI-CIII-AIV gene cluster and familial combined hyperlipidaemia. Clin. Genet. 46, 385-397 (1994).
-
(1994)
Clin. Genet.
, vol.46
, pp. 385-397
-
-
Xu, C.F.1
-
70
-
-
0025902231
-
Inhibition of early atherogenesis in transgenic mice by human apolipoprotein Al
-
Rubin, E. M., Krauss, R. M., Spangler, E. A., Verstuyft, J. G. & Clift, S. M. Inhibition of early atherogenesis in transgenic mice by human apolipoprotein AI. Nature 353, 265-267 (1991). (Pubitemid 21896769)
-
(1991)
Nature
, vol.353
, Issue.6341
, pp. 265-267
-
-
Rubin, E.M.1
Krauss, R.M.2
Spangler, E.A.3
Verstuyft, J.G.4
Clift, S.M.5
-
71
-
-
0030911585
-
Chylomicronemia due to apolipoprotein CIII overexpression in apolipoprotein E-null mice. Apolipoprotein CIII-induced hypertriglyceridemia is not mediated by effects on apolipoprotein E
-
Ebara, T., Ramakrishnan, R., Steiner, G. & Shachter, N. S. Chylomicronemia due to apolipoprotein CIII overexpression in apolipoprotein E-null mice. Apolipoprotein CIII-induced hypertriglyceridemia is not mediated by effects on apolipoprotein E. J. Clin. Invest. 99, 2672-2681 (1997). (Pubitemid 27259814)
-
(1997)
Journal of Clinical Investigation
, vol.99
, Issue.11
, pp. 2672-2681
-
-
Ebara, T.1
Ramakrishnan, R.2
Steiner, G.3
Shachter, N.S.4
-
72
-
-
0030944085
-
Reduced aortic lesions and elevated high density lipoprotein levels in transgenic mice overexpressing mouse apolipoprotein A-IV
-
Cohen, R. D. et al. Reduced aortic lesions and elevated high density lipoprotein levels in transgenic mice overexpressing mouse apolipoprotein A-IV. J. Clin. Invest. 99, 1906-1916 (1997). (Pubitemid 27175938)
-
(1997)
Journal of Clinical Investigation
, vol.99
, Issue.8
, pp. 1906-1916
-
-
Cohen, R.D.1
Castellani, L.W.2
Qiao, J.-H.3
Van Lenten, B.J.4
Lusis, A.J.5
Reue, K.6
-
73
-
-
0035812707
-
An apolipoprotein influencing triglycerides in humans and mice revealed by comparative sequencing
-
DOI 10.1126/science.1064852
-
Pennacchio, L. A. et al. An apolipoprotein influencing triglycerides in humans and mice revealed by comparative sequencing. Science 294, 169-173 (2001). (Pubitemid 32952971)
-
(2001)
Science
, vol.294
, Issue.5540
, pp. 169-173
-
-
Pennacchio, L.A.1
Olivier, M.2
Hubacek, J.A.3
Cohen, J.C.4
Cox, D.R.5
Fruchart, J.-C.6
Krauss, R.M.7
Rubin, E.M.8
-
74
-
-
13444256227
-
Insulin-mediated down-regulation of apolipoprotein A5 gene expression through the phosphatidylinositol 3-kinase pathway: Role of upstream stimulatory factor
-
DOI 10.1128/MCB.25.4.1537-1548.2005
-
Nowak, M. et al. Insulin-mediated down-regulation of apolipoprotein A5 gene expression through the phosphatidylinositol 3-kinase pathway: role of upstream stimulatory factor. Mol. Cell Biol. 25, 1537-1548 (2005). (Pubitemid 40204928)
-
(2005)
Molecular and Cellular Biology
, vol.25
, Issue.4
, pp. 1537-1548
-
-
Nowak, M.1
Helleboid-Chapman, A.2
Jakel, H.3
Martin, G.4
Duran-Sandoval, D.5
Staels, B.6
Rubin, E.M.7
Pennacchio, L.A.8
Taskinen, M.-R.9
Fruchart-Najib, J.10
Fruchart, J.-C.11
-
75
-
-
75149172789
-
Genetic association and interaction analysis of USF1 and APOA5 on lipid levels and atherosclerosis
-
Laurila, P. P. et al. Genetic association and interaction analysis of USF1 and APOA5 on lipid levels and atherosclerosis. Arterioscler. Thromb. Vasc. Biol. 30, 346-352 (2010).
-
(2010)
Arterioscler. Thromb. Vasc. Biol.
, vol.30
, pp. 346-352
-
-
Laurila, P.P.1
-
76
-
-
11144355229
-
Association of the APOLIPOPROTEIN A1/C3/A4/A5 Gene Cluster with Triglyceride Levels and LDL Particle Size in Familial Combined Hyperlipidemia
-
DOI 10.1161/01.RES.0000124922.61830.F0
-
Mar, R. et al. Association of the apolipoprotein A1/C3/A4/A5 gene cluster with triglyceride levels and LDL particle size in familial combined hyperlipidemia. Circ. Res. 94, 993-999 (2004). (Pubitemid 38490078)
-
(2004)
Circulation Research
, vol.94
, Issue.7
, pp. 993-999
-
-
Mar, R.1
Pajukanta, P.2
Allayee, H.3
Groenendijk, M.4
Dallinga-Thie, G.5
Krauss, R.M.6
Sinsheimer, J.S.7
Cantor, R.M.8
De Bruin, T.W.A.9
Lusis, A.J.10
-
77
-
-
77952357848
-
High-density lipoprotein heterogeneity and function in reverse cholesterol transport
-
Rothblat, G. H. & Phillips, M. C. High-density lipoprotein heterogeneity and function in reverse cholesterol transport. Curr. Opin. Lipidol. 21, 229-238 (2010).
-
(2010)
Curr. Opin. Lipidol.
, vol.21
, pp. 229-238
-
-
Rothblat, G.H.1
Phillips, M.C.2
-
78
-
-
0038467375
-
Biochemical and genetic association of plasma apolipoprotein A-II levels with familial combined hyperlipidemia
-
DOI 10.1161/01.RES.0000075600.87675.16
-
Allayee, H., Castellani, L. W., Cantor, R. M., de Bruin, T. W. & Lusis, A. J. Biochemical and genetic association of plasma apolipoprotein A-II levels with familial combined hyperlipidemia. Circ. Res. 92, 1262-1267 (2003). (Pubitemid 36723655)
-
(2003)
Circulation Research
, vol.92
, Issue.11
, pp. 1262-1267
-
-
Allayee, H.1
Castellani, L.W.2
Cantor, R.M.3
De Bruin, T.W.A.4
Lusis, A.J.5
-
79
-
-
79953204259
-
Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease
-
Schunkert, H. et al. Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease. Nat. Genet. 43, 333-338 (2011).
-
(2011)
Nat. Genet.
, vol.43
, pp. 333-338
-
-
Schunkert, H.1
-
80
-
-
34547623750
-
Genomewide association analysis of coronary artery disease
-
DOI 10.1056/NEJMoa072366
-
Samani, N. J. et al. Genomewide association analysis of coronary artery disease. N. Engl. J. Med. 357, 443-453 (2007). (Pubitemid 47204873)
-
(2007)
New England Journal of Medicine
, vol.357
, Issue.5
, pp. 443-453
-
-
Samani, N.J.1
Erdmann, J.2
Hall, A.S.3
Hengstenberg, C.4
Mangino, M.5
Mayer, B.6
Dixon, R.J.7
Meitinger, T.8
Braund, P.9
Wichmann, H.-E.10
Barrett, J.H.11
Konig, I.R.12
Stevens, S.E.13
Szymczak, S.14
Tregouet, D.-A.15
Iles, M.M.16
Pahlke, F.17
Pollard, H.18
Lieb, W.19
Cambien, F.20
Fischer, M.21
Ouwehand, W.22
Blankenberg, S.23
Balmforth, A.J.24
Baessler, A.25
Ball, S.G.26
Strom, T.M.27
Braenne, I.28
Gieger, C.29
Deloukas, P.30
Tobin, M.D.31
Ziegler, A.32
Thompson, J.R.33
Schunkert, H.34
more..
-
81
-
-
54349112435
-
Frequency of low-density lipoprotein receptor gene mutations in patients with a clinical diagnosis of familial combined hyperlipidemia in a clinical setting
-
Civeira, F. et al. Frequency of low-density lipoprotein receptor gene mutations in patients with a clinical diagnosis of familial combined hyperlipidemia in a clinical setting. J. Am. Coll. Cardiol. 52, 1546-1553 (2008).
-
(2008)
J. Am. Coll. Cardiol.
, vol.52
, pp. 1546-1553
-
-
Civeira, F.1
-
82
-
-
0025302745
-
Genetic evidence from 7 families that the apolipoprotein B gene is not involved in familial combined hyperlipidemia
-
DOI 10.1016/0021-9150(90)90133-4
-
Rauh, G. et al. Genetic evidence from 7 families that the apolipoprotein B gene is not involved in familial combined hyperlipidemia. Atherosclerosis 83, 81-87 (1990). (Pubitemid 20210748)
-
(1990)
Atherosclerosis
, vol.83
, Issue.1
, pp. 81-87
-
-
Rauh, G.1
Schuster, H.2
Muller, B.3
Schewe, S.4
Keller, C.5
Wolfram, G.6
Zollner, N.7
-
83
-
-
0026341578
-
Lack of evidence for linkage between low-density lipoprotein subclass phenotypes and the apolipoprotein B locus in familial combined hyperlipidemia
-
Austin, M. A. et al. Lack of evidence for linkage between low-density lipoprotein subclass phenotypes and the apolipoprotein B locus in familial combined hyperlipidemia. Genet. Epidemiol. 8, 287-297 (1991).
-
(1991)
Genet. Epidemiol.
, vol.8
, pp. 287-297
-
-
Austin, M.A.1
-
84
-
-
0026395138
-
Polymorphisms of the apolipoprotein B and e genes and their possible roles in familial and non-familial combined hyperlipidaemia
-
Houlston, R., Lewis, B. & Humphries, S. E. Polymorphisms of the apolipoprotein B and E genes and their possible roles in familial and non-familial combined hyperlipidaemia. Dis. Markers 9, 319-325 (1991).
-
(1991)
Dis. Markers
, vol.9
, pp. 319-325
-
-
Houlston, R.1
Lewis, B.2
Humphries, S.E.3
-
85
-
-
0037603589
-
Mutations in PCSK9 cause autosomal dominant hypercholesterolemia
-
DOI 10.1038/ng1161
-
Abifadel, M. et al. Mutations in PCSK9 cause autosomal dominant hypercholesterolemia. Nat. Genet. 34, 154-156 (2003). (Pubitemid 36666925)
-
(2003)
Nature Genetics
, vol.34
, Issue.2
, pp. 154-156
-
-
Abifadel, M.1
Varret, M.2
Rabes, J.-P.3
Allard, D.4
Ouguerram, K.5
Devillers, M.6
Cruaud, C.7
Benjannet, S.8
Wickham, L.9
Erlich, D.10
Derre, A.11
Villeger, L.12
Farnier, M.13
Beucler, I.14
Bruckert, E.15
Chambaz, J.16
Chanu, B.17
Lecerf, J.-M.18
Luc, G.19
Moulin, P.20
Weissenbach, J.21
Prat, A.22
Krempf, M.23
Junien, C.24
Seidah, N.G.25
Boileau, C.26
more..
-
86
-
-
57349089246
-
A PCSK9 variant and familial combined hyperlipidaemia
-
Abifadel, M. et al. A PCSK9 variant and familial combined hyperlipidaemia. J. Med. Genet. 45, 780-786 (2008).
-
(2008)
J. Med. Genet.
, vol.45
, pp. 780-786
-
-
Abifadel, M.1
-
87
-
-
80052328701
-
Plasma proprotein convertase subtilisin kexin type 9 is a heritable trait of familial combined hyperlipidaemia
-
Brouwers, M. C. et al. Plasma proprotein convertase subtilisin kexin type 9 is a heritable trait of familial combined hyperlipidaemia. Clin. Sci. (Lond.) 121, 397-403 (2011).
-
(2011)
Clin. Sci. (Lond.)
, vol.121
, pp. 397-403
-
-
Brouwers, M.C.1
-
88
-
-
1842509855
-
ATF6 modulates SREBP2-mediated lipogenesis
-
DOI 10.1038/sj.emboj.7600106
-
Zeng, L. et al. ATF6 modulates SREBP2-mediated lipogenesis. EMBO J. 23, 950-958 (2004). (Pubitemid 38418761)
-
(2004)
EMBO Journal
, vol.23
, Issue.4
, pp. 950-958
-
-
Zeng, L.1
Lu, M.2
Mori, K.3
Luo, S.4
Lee, A.S.5
Zhu, Y.6
Shyy, J.Y.-J.7
-
89
-
-
0026730609
-
Metabolism of plasma low density lipoproteins in familial combined hyperlipidaemia: Effect of acipimox therapy
-
Ericsson, S., Eriksson, M., Berglund, L. & Angelin, B. Metabolism of plasma low density lipoproteins in familial combined hyperlipidaemia: effect of acipimox therapy. J. Intern. Med. 232, 313-320 (1992).
-
(1992)
J. Intern. Med.
, vol.232
, pp. 313-320
-
-
Ericsson, S.1
Eriksson, M.2
Berglund, L.3
Angelin, B.4
-
90
-
-
73449117605
-
Genetic determinants of circulating sphingolipid concentrations in European populations
-
Hicks, A. A. et al. Genetic determinants of circulating sphingolipid concentrations in European populations. PLoS Genet. 5, e1000672 (2009).
-
(2009)
PLoS Genet.
, vol.5
-
-
Hicks, A.A.1
-
91
-
-
66349102249
-
New technologies for delineating and characterizing the lipid exome: Prospects for understanding familial combined hyperlipidemia
-
Horswell, S. D., Ringham, H. E. & Shoulders, C. C. New technologies for delineating and characterizing the lipid exome: prospects for understanding familial combined hyperlipidemia. J. Lipid Res. 50 (Suppl.), S370-S375 (2009).
-
(2009)
Lipid Res.
, vol.50
, Issue.SUPPL.
-
-
Horswell, S.D.1
Ringham, H.E.2
Shoulders, C.C.3
-
92
-
-
77954162542
-
Use of genome-wide expression data to mine the "gray Zone" of GWA studies leads to novel candidate obesity genes
-
Naukkarinen, J. et al. Use of genome-wide expression data to mine the "Gray Zone" of GWA studies leads to novel candidate obesity genes. PLoS Genet. 6, e1000976 (2010).
-
(2010)
PLoS Genet.
, vol.6
-
-
Naukkarinen, J.1
-
93
-
-
33747039577
-
Common hepatic nuclear factor-4α variants are associated with high serum lipid levels and the metabolic syndrome
-
DOI 10.2337/db06-0035
-
Weissglas-Volkov, D. et al. Common hepatic nuclear factor-4α variants are associated with high serum lipid levels and the metabolic syndrome. Diabetes 55, 1970-1977 (2006). (Pubitemid 44509969)
-
(2006)
Diabetes
, vol.55
, Issue.7
, pp. 1970-1977
-
-
Weissglas-Volkov, D.1
Huertas-Vazquez, A.2
Suviolahti, E.3
Lee, J.4
Plaisier, C.5
Canizales-Quinteros, S.6
Tusie-Luna, T.7
Aguilar-Salinas, C.8
Taskinen, M.-R.9
Pajukanta, P.10
-
94
-
-
70349656509
-
A systems genetics approach implicates USF1 FADS3 and other causal candidate genes for familial combined hyperlipidemia
-
Plaisier, C. L. et al. A systems genetics approach implicates USF1, FADS3, and other causal candidate genes for familial combined hyperlipidemia. PLoS Genet. 5, e1000642 (2009).
-
(2009)
PLoS Genet.
, vol.5
-
-
Plaisier, C.L.1
-
95
-
-
70349956433
-
Finding the missing heritability of complex diseases
-
Manolio, T. A. et al. Finding the missing heritability of complex diseases. Nature 461, 747-753 (2009).
-
(2009)
Nature
, vol.461
, pp. 747-753
-
-
Manolio, T.A.1
-
96
-
-
0037146578
-
Genetics: Finding genes that underline complex traits
-
DOI 10.1126/science.1076641
-
Glazier, A. M., Nadeau, J. H. & Aitman, T. J. Finding genes that underlie complex traits. Science 298, 2345-2349 (2002). (Pubitemid 36014199)
-
(2002)
Science
, vol.298
, Issue.5602
, pp. 2345-2349
-
-
Glazier, A.M.1
Nadeau, J.H.2
Aitman, T.J.3
-
97
-
-
77953381261
-
Linkage and association analyses identify a candidate region for apoB level on chromosome 4q32.3 in FCHL families
-
Wijsman, E. M. et al. Linkage and association analyses identify a candidate region for apoB level on chromosome 4q32.3 in FCHL families. Hum. Genet. 127, 705-719 (2010).
-
(2010)
Hum. Genet.
, vol.127
, pp. 705-719
-
-
Wijsman, E.M.1
-
98
-
-
79960943621
-
Fine mapping of five loci associated with low-density lipoprotein cholesterol detects variants that double the explained heritability
-
Sanna, S. et al. Fine mapping of five loci associated with low-density lipoprotein cholesterol detects variants that double the explained heritability. PLoS Genet. 7, e1002198 (2011).
-
(2011)
PLoS Genet.
, vol.7
-
-
Sanna, S.1
-
99
-
-
33744470566
-
The Gln223Arg polymorphism in the leptin receptor is associated with familial combined hyperlipidemia
-
DOI 10.1038/sj.ijo.0803234, PII 0803234
-
van der Vleuten, G. M. et al. The Gln223Arg polymorphism in the leptin receptor is associated with familial combined hyperlipidemia. Int. J. Obes. (Lond.) 30, 892-898 (2006). (Pubitemid 43801187)
-
(2006)
International Journal of Obesity
, vol.30
, Issue.6
, pp. 892-898
-
-
Van Der Vleuten, G.M.1
Kluijtmans, L.A.2
Hijmans, A.3
Blom, H.J.4
Stalenhoef, A.F.H.5
De Graaf, J.6
-
100
-
-
0033757442
-
Genome scan for adiposity in Dutch dyslipidemic families reveals novel quantitative trait loci for leptin, body mass index and soluble tumor necrosis factor receptor superfamily 1A
-
van der Kallen, C. J. et al. Genome scan for adiposity in Dutch dyslipidemic families reveals novel quantitative trait loci for leptin, body mass index and soluble tumor necrosis factor receptor superfamily 1A. Int. J. Obes. Relat. Metab. Disord. 24, 1381-1391 (2000).
-
(2000)
Int. J. Obes. Relat. Metab. Disord.
, vol.24
, pp. 1381-1391
-
-
Van Der Kallen, C.J.1
-
101
-
-
33745049061
-
Longitudinal differences in familial combined hyperlipidemia quantitative trait loci [2]
-
DOI 10.1161/01.ATV.0000221232.79877.c7, PII 0004360520060600000038
-
Brouwers, M. C. et al. Longitudinal differences in familial combined hyperlipidemia quantitative trait loci. Arterioscler. Thromb. Vasc. Biol. 26, e118-e119 (2006). (Pubitemid 44305391)
-
(2006)
Arteriosclerosis, Thrombosis, and Vascular Biology
, vol.26
, Issue.6
-
-
Brouwers, M.C.G.J.1
-
102
-
-
0037013151
-
Locus for elevated apolipoprotein B levels on chromosome 1p31 in families with familial combined hyperlipidemia
-
DOI 10.1161/01.RES.0000015885.27134.F0
-
Allayee, H. et al. Locus for elevated apolipoprotein B levels on chromosome 1p31 in families with familial combined hyperlipidemia. Circ. Res. 90, 926-931 (2002). (Pubitemid 34633886)
-
(2002)
Circulation Research
, vol.90
, Issue.8
, pp. 926-931
-
-
Allayee, H.1
Krass, K.L.2
Pajukanta, P.3
Cantor, R.M.4
Van Der Kallen, C.J.H.5
Mar, R.6
Rotter, J.I.7
De Bruin, T.W.A.8
Peltonen, L.9
Lusis, A.J.10
-
103
-
-
78650107057
-
Lipolysis-a highly regulated multi-enzyme complex mediates the catabolism of cellular fat stores
-
Lass, A., Zimmermann, R., Oberer, M. & Zechner, R. Lipolysis-a highly regulated multi-enzyme complex mediates the catabolism of cellular fat stores. Prog. Lipid Res. 50, 14-27 (2011).
-
(2011)
Prog. Lipid Res.
, vol.50
, pp. 14-27
-
-
Lass, A.1
Zimmermann, R.2
Oberer, M.3
Zechner, R.4
-
104
-
-
0142154034
-
Variants in the PPARγ gene affect fatty acid and glycerol metabolism in familial combined hyperlipidemia
-
DOI 10.1016/S1096-7192(03)00138-0
-
Eurlings, P. M., van der Kallen, C. J., Vermeulen, V. M. & de Bruin, T. W. Variants in the PPARgamma gene affect fatty acid and glycerol metabolism in familial combined hyperlipidemia. Mol. Genet. Metab. 80, 296-301 (2003). (Pubitemid 37324715)
-
(2003)
Molecular Genetics and Metabolism
, vol.80
, Issue.3
, pp. 296-301
-
-
Eurlings, P.M.H.1
Van Der Kallen, C.J.H.2
Vermeulen, V.M.M.-J.3
De Bruin, T.W.A.4
-
105
-
-
0033624612
-
The Pro12Ala substitution in the peroxisome proliferator activated receptor gamma 2 is associated with an insulin-sensitive phenotype in families with familial combined hyperlipidemia and in nondiabetic elderly subjects with dyslipidemia
-
DOI 10.1016/S0021-9150(99)00433-5, PII S0021915099004335
-
Pihlajamäki, J. et al. The Pro12A1a substitution in the peroxisome proliferator activated receptor gamma 2 is associated with an insulin-sensitive phenotype in families with familial combined hyperlipidemia and in nondiabetic elderly subjects with dyslipidemia. Atherosclerosis 151, 567-574 (2000). (Pubitemid 30618776)
-
(2000)
Atherosclerosis
, vol.151
, Issue.2
, pp. 567-574
-
-
Pihlajamaki, J.1
Miettinen, R.2
Valve, R.3
Karjalainen, L.4
Mykkanen, L.5
Kuusisto, J.6
Deeb, S.7
Auwerx, J.8
Laakso, M.9
-
106
-
-
24144469193
-
Genome scan for quantitative trait loci influencing HDL levels: Evidence for multilocus inheritance in familial combined hyperlipidemia
-
DOI 10.1007/s00439-005-1338-4
-
Gagnon, F. et al. Genome scan for quantitative trait loci influencing HDL levels: evidence for multilocus inheritance in familial combined hyperlipidemia. Hum. Genet. 117, 494-505 (2005). (Pubitemid 41236371)
-
(2005)
Human Genetics
, vol.117
, Issue.5
, pp. 494-505
-
-
Gagnon, F.1
Jarvik, G.P.2
Badzioch, M.D.3
Motulsky, A.G.4
Brunzell, J.D.5
Wijsman, E.M.6
-
107
-
-
35148883209
-
USF1 contributes to high serum lipid levels in Dutch FCHL families and U.S. Whites with coronary artery disease
-
DOI 10.1161/ATVBAHA.107.151530
-
Lee, J. C. et al. USF1 contributes to high serum lipid levels in Dutch FCHL families and U. S. whites with coronary artery disease. Arterioscler. Thromb. Vasc. Biol. 27, 2222-2227 (2007). (Pubitemid 350287253)
-
(2007)
Arteriosclerosis, Thrombosis, and Vascular Biology
, vol.27
, Issue.10
, pp. 2222-2227
-
-
Lee, J.C.1
Weissglas-Volkov, D.2
Kyttala, M.3
Sinsheimer, J.S.4
Jokiaho, A.5
De Bruin, T.W.A.6
Lusis, A.J.7
Brennan, M.-L.8
Van Greevenbroek, M.M.J.9
Van Der Kallen, C.J.H.10
Hazen, S.L.11
Pajukanta, P.12
-
108
-
-
33846002317
-
The involvement of upstream stimulatory factor 1 in Dutch patients with familial combined hyperlipidemia
-
DOI 10.1194/jlr.M600184-JLR200
-
van der Vleuten, G. M. et al. The involvement of upstream stimulatory factor 1 in Dutch patients with familial combined hyperlipidemia. J. Lipid Res. 48, 193-200 (2007). (Pubitemid 46052911)
-
(2007)
Journal of Lipid Research
, vol.48
, Issue.1
, pp. 193-200
-
-
Van Der Vleuten, G.M.1
Isaacs, A.2
Hijmans, A.3
Van Duijn, C.M.4
Stalenhoef, A.F.H.5
De Graaf, J.6
-
109
-
-
5344220303
-
Low-density lipoprotein particle size loci in familial combined hyperlipidemia: Evidence for multiple loci from a genome scan
-
DOI 10.1161/01.ATV.0000143499.09575.93
-
Badzioch, M. D. et al. Low-density lipoprotein particle size loci in familial combined hyperlipidemia: evidence for multiple loci from a genome scan. Arterioscler. Thromb. Vasc. Biol. 24, 1942-1950 (2004). (Pubitemid 39350317)
-
(2004)
Arteriosclerosis, Thrombosis, and Vascular Biology
, vol.24
, Issue.10
, pp. 1942-1950
-
-
Badzioch, M.D.1
Igo Jr., R.P.2
Gagnon, F.3
Brunzell, J.D.4
Krauss, R.M.5
Motulsky, A.G.6
Wijsman, E.M.7
Jarvik, G.P.8
-
110
-
-
0033999663
-
Markedly increased secretion of VLDL triglycerides induced by gene transfer of apolipoprotein E isoforms in apoE-deficient mice
-
Tsukamoto, K., Maugeais, C., Glick, J. M. & Rader, D. J. Markedly increased secretion of VLDL triglycerides induced by gene transfer of apolipoprotein E isoforms in apoE-deficient mice. J. Lipid Res. 41, 253-259 (2000). (Pubitemid 30117866)
-
(2000)
Journal of Lipid Research
, vol.41
, Issue.2
, pp. 253-259
-
-
Tsukamoto, K.1
Maugeais, C.2
Glick, J.M.3
Rader, D.J.4
-
111
-
-
33751424634
-
Apolipoprotein e polymorphism influences lipid phenotypes in Chinese families with familial combined hyperlipidemia
-
Pei, W. D. et al. Apolipoprotein E polymorphism influences lipid phenotypes in Chinese families with familial combined hyperlipidemia. Circ. J. 70, 1606-1610 (2006).
-
(2006)
Circ. J.
, vol.70
, pp. 1606-1610
-
-
Pei, W.D.1
-
112
-
-
0030601668
-
Apolipoprotein E polymorphism influences lipid phenotypic expression, but not the low density lipoprotein subfraction distribution in familial combined hyperlipidemia
-
DOI 10.1016/0021-9150(96)05924-2
-
Bredie, S. J., Vogelaar, J. M., Demacker, P. N. & Stalenhoef, A. F. Apolipoprotein E polymorphism influences lipid phenotypic expression, but not the low density lipoprotein subfraction distribution in familial combined hyperlipidemia. Atherosclerosis 126, 313-324 (1996). (Pubitemid 26336668)
-
(1996)
Atherosclerosis
, vol.126
, Issue.2
, pp. 313-324
-
-
Bredie, S.J.H.1
Vogelaar, J.M.2
Demacker, P.N.M.3
Stalenhoef, A.F.H.4
-
113
-
-
79952275879
-
Galanin and consummatory behavior: Special relationship with dietary fat, alcohol and circulating lipids
-
Barson, J. R., Morganstern, I. & Leibowitz, S. F. Galanin and consummatory behavior: special relationship with dietary fat, alcohol and circulating lipids. EXS 102, 87-111 (2010).
-
(2010)
EXS
, vol.102
, pp. 87-111
-
-
Barson, J.R.1
Morganstern, I.2
Leibowitz, S.F.3
-
114
-
-
80053452394
-
Large-scale gene-centric analysis identifies novel variants for coronary artery disease
-
IBC 50K CAD Consortium.
-
IBC 50K CAD Consortium. Large-scale gene-centric analysis identifies novel variants for coronary artery disease. PLoS Genet. 7, e1002260 (2011).
-
(2011)
PLoS Genet.
, vol.7
-
-
-
115
-
-
70349263990
-
OSBPL10, a novel candidate gene for high triglyceride trait in dyslipidemic Finnish subjects, regulates cellular lipid metabolism
-
Perttilä, J. et al. OSBPL10, a novel candidate gene for high triglyceride trait in dyslipidemic Finnish subjects, regulates cellular lipid metabolism. J. Mol. Med. (Berl.) 87, 825-835 (2009).
-
(2009)
J. Mol. Med. (Berl.)
, vol.87
, pp. 825-835
-
-
Perttilä, J.1
-
116
-
-
0030937346
-
Complex genetic contribution of the Apo AI-CIII-AIV gene cluster to familial combined hyperlipidemia: Identification of different susceptibility haplotypes
-
Dallinga-Thie, G. M. et al. Complex genetic contribution of the Apo AI-CIII-AIV gene cluster to familial combined hyperlipidemia. Identification of different susceptibility haplotypes. J. Clin. Invest. 99, 953-961 (1997). (Pubitemid 27123632)
-
(1997)
Journal of Clinical Investigation
, vol.99
, Issue.5
, pp. 953-961
-
-
Dallinga-Thie, G.M.1
-
117
-
-
0032231670
-
Families with familial combined hyperlipidemia and families enriched for coronary artery disease share genetic determinants for the atherogenic lipoprotein phenotype
-
DOI 10.1086/301983
-
Allayee, H. et al. Families with familial combined hyperlipidemia and families enriched for coronary artery disease share genetic determinants for the atherogenic lipoprotein phenotype. Am. J. Hum. Genet. 63, 577-585 (1998). (Pubitemid 30418640)
-
(1998)
American Journal of Human Genetics
, vol.63
, Issue.2
, pp. 577-585
-
-
Allayee, H.1
Aouizerat, B.E.2
Cantor, R.M.3
Dallinga-Thie, G.M.4
Krauss, R.M.5
Lanning, C.D.6
Rotter, J.I.7
Lusis, A.J.8
De Bruin, T.W.A.9
-
118
-
-
0029838836
-
Two novel apolipoprotein A-IV variants in individuals with familial combined hyperlipidemia and diminished levels of lipoprotein lipase activity
-
DOI 10.1002/(SICI)1098-1004(1996)8:4<319::AID-HUMU4>3.0.CO;2-2
-
Deeb, S. S., Nevin, D. N., Iwasaki, L. & Brunzell, J. D. Two novel apolipoprotein A-IV variants in individuals with familial combined hyperlipidemia and diminished levels of lipoprotein lipase activity. Hum. Mutat. 8, 319-325 (1996). (Pubitemid 26412147)
-
(1996)
Human Mutation
, vol.8
, Issue.4
, pp. 319-325
-
-
Deeb, S.S.1
Nevin, D.N.2
Iwasaki, L.3
Brunzell, J.D.4
-
119
-
-
0242690899
-
Evidence of linkage of HDL level variation to APOC3 in two samples with different ascertainment
-
DOI 10.1007/s00439-003-1006-5
-
Gagnon, F. et al. Evidence of linkage of HDL level variation to APOC3 in two samples with different ascertainment. Hum. Genet. 113, 522-533 (2003). (Pubitemid 37383767)
-
(2003)
Human Genetics
, vol.113
, Issue.6
, pp. 522-533
-
-
Gagnon, F.1
Jarvik, G.P.2
Motulsky, A.G.3
Deeb, S.S.4
Brunzell, J.D.5
Wijsman, E.M.6
-
120
-
-
34248343423
-
Characterization of apolipoprotein A-V structure and mode of plasma triacylglycerol regulation
-
DOI 10.1097/MOL.0b013e328133856c, PII 0004143320070600000015
-
Wong, K. & Ryan, R. O. Characterization of apolipoprotein A-V structure and mode of plasma triacylglycerol regulation. Curr. Opin. Lipidol. 18, 319-324 (2007). (Pubitemid 46743057)
-
(2007)
Current Opinion in Lipidology
, vol.18
, Issue.3
, pp. 319-324
-
-
Wong, K.1
Ryan, R.O.2
-
121
-
-
0038043229
-
Apolipoprotein A5, a crucial determinant of plasma triglyceride levels, is highly responsive to peroxisome proliferator-activated receptor α activators
-
DOI 10.1074/jbc.M212191200
-
Vu-Dac, N. et al. Apolipoprotein A5, a crucial determinant of plasma triglyceride levels, is highly responsive to peroxisome proliferator-activated receptor alpha activators. J. Biol. Chem. 278, 17982-17985 (2003). (Pubitemid 36799406)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.20
, pp. 17982-17985
-
-
Vu-Dac, N.1
Gervois, P.2
Jakel, H.3
Nowak, M.4
Bauge, E.5
Dehondt, H.6
Staels, B.7
Pennacchio, L.A.8
Rubin, E.M.9
Fruchart-Najib, J.10
Fruchart, J.-C.11
-
122
-
-
23044515047
-
Thyroid hormone regulates the hypotriglyceridemic gene APOA5
-
DOI 10.1074/jbc.M503139200
-
Prieur, X. et al. Thyroid hormone regulates the hypotriglyceridemic gene APOA5. J. Biol. Chem. 280, 27533-27543 (2005). (Pubitemid 41076864)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.30
, pp. 27533-27543
-
-
Prieur, X.1
Huby, T.2
Coste, H.3
Schaap, F.G.4
Chapman, M.J.5
Rodriguez, J.C.6
-
123
-
-
33845750091
-
Haplotype analyses of the APOA5 gene in patients with familial combined hyperlipidemia
-
van der Vleuten, G. M. et al. Haplotype analyses of the APOA5 gene in patients with familial combined hyperlipidemia. Biochim. Biophys. Acta 1772, 81-88 (2007).
-
(2007)
Biochim. Biophys. Acta
, vol.1772
, pp. 81-88
-
-
Van Der Vleuten, G.M.1
-
124
-
-
74749108129
-
Associations of polymorphisms in the apolipoprotein A1/C3/A4/A5 gene cluster with familial combined hyperlipidaemia in Hong Kong Chinese
-
Liu, Z. K., Hu, M., Baum, L., Thomas, G. N. & Tomlinson, B. Associations of polymorphisms in the apolipoprotein A1/C3/A4/A5 gene cluster with familial combined hyperlipidaemia in Hong Kong Chinese. Atherosclerosis 208, 427-432 (2010).
-
(2010)
Atherosclerosis
, vol.208
, pp. 427-432
-
-
Liu, Z.K.1
Hu, M.2
Baum, L.3
Thomas, G.N.4
Tomlinson, B.5
-
125
-
-
0036720541
-
Newly identified apolipoprotein AV gene predisposes to high plasma triglycerides in familial combined hyperlipidemia
-
Ribalta, J. et al. Newly identified apolipoprotein AV gene predisposes to high plasma triglycerides in familial combined hyperlipidemia. Clin. Chem. 48, 1597-1600 (2002). (Pubitemid 34925802)
-
(2002)
Clinical Chemistry
, vol.48
, Issue.9
, pp. 1597-1600
-
-
Ribalta, J.1
Figuera, L.2
Fernandez-Ballart, J.3
Vilella, E.4
Castro Cabezas, M.5
Masana, L.6
Joven, J.7
-
126
-
-
53149113099
-
The value of HDL genetics
-
Holleboom, A. G., Vergeer, M., Hovingh, G. K., Kastelein, J. J. & Kuivenhoven, J. A. The value of HDL genetics. Curr. Opin. Lipidol. 19, 385-394 (2008).
-
(2008)
Curr. Opin. Lipidol.
, vol.19
, pp. 385-394
-
-
Holleboom, A.G.1
Vergeer, M.2
Hovingh, G.K.3
Kastelein, J.J.4
Kuivenhoven, J.A.5
-
127
-
-
0033913206
-
G-250A substitution in promoter of hepatic lipase gene is associated with dyslipidemia and insulin resistance in healthy control subjects and in members of families with familial combined hyperlipidemia
-
Pihlajamäki, J. et al. G-250A substitution in promoter of hepatic lipase gene is associated with dyslipidemia and insulin resistance in healthy control subjects and in members of families with familial combined hyperlipidemia. Arterioscler. Thromb. Vasc. Biol. 20, 1789-1795 (2000). (Pubitemid 30470595)
-
(2000)
Arteriosclerosis, Thrombosis, and Vascular Biology
, vol.20
, Issue.7
, pp. 1789-1795
-
-
Pihlajamaki, J.1
Karjalainen, L.2
Karhapaa, P.3
Vauhkonen, I.4
Taskinen, M.-R.5
Deeb, S.S.6
Laakso, M.7
-
128
-
-
0033996456
-
Contribution of the hepatic lipase gene to the atherogenic lipoprotein phenotype in familial combined hyperlipidemia
-
Allayee, H. et al. Contribution of the hepatic lipase gene to the atherogenic lipoprotein phenotype in familial combined hyperlipidemia. J. Lipid Res. 41, 245-252 (2000). (Pubitemid 30117865)
-
(2000)
Journal of Lipid Research
, vol.41
, Issue.2
, pp. 245-252
-
-
Allayee, H.1
Dominguez, K.M.2
Aouizerat, B.E.3
Krauss, R.M.4
Rotter, J.I.5
Lu, J.6
Cantor, R.M.7
De Bruin, T.W.A.8
Lusis, A.J.9
-
129
-
-
70749096913
-
Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants
-
Kathiresan, S. et al. Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants. Nat. Genet. 41, 334-341 (2009).
-
(2009)
Nat. Genet.
, vol.41
, pp. 334-341
-
-
Kathiresan, S.1
-
130
-
-
0033362163
-
A genome scan for familial combined hyperlipidemia reveals evidence of linkage with a locus on chromosome 11
-
DOI 10.1086/302490
-
Aouizerat, B. E. et al. A genome scan for familial combined hyperlipidemia reveals evidence of linkage with a locus on chromosome 11. Am. J. Hum. Genet. 65, 397-412 (1999). (Pubitemid 30462997)
-
(1999)
American Journal of Human Genetics
, vol.65
, Issue.2
, pp. 397-412
-
-
Aouizerat, B.E.1
Allayee, H.2
Cantor, R.M.3
Davis, R.C.4
Lanning, C.D.5
Wen, P.-Z.6
Dallinga-Thie, G.M.7
De Bruin, T.W.A.8
Rotter, J.I.9
Lusis, A.J.10
-
131
-
-
0033929093
-
Adducin structure, function and regulation
-
Matsuoka, Y., Li, X. & Bennett, V. Adducin: structure, function and regulation. Cell. Mol. Life Sci. 57, 884-895 (2000).
-
(2000)
Cell. Mol. Life Sci.
, vol.57
, pp. 884-895
-
-
Matsuoka, Y.1
Li, X.2
Bennett, V.3
-
132
-
-
0035216259
-
Association between the α-adducin Gly460Trp polymorphism and systolic blood pressure in familial combined hyperlipidemia
-
DOI 10.1016/S0895-7061(01)02216-6, PII S0895706101022166
-
Beeks, E. et al. Association between the alpha-adducin Gly460Trp polymorphism and systolic blood pressure in familial combined hyperlipidemia. Am. J. Hypertens. 14, 1185-1190 (2001). (Pubitemid 33151472)
-
(2001)
American Journal of Hypertension
, vol.14
, Issue.12
, pp. 1185-1190
-
-
Beeks, E.1
Janssen, R.G.J.H.2
Kroon, A.A.3
Keulen, E.T.P.4
Geurts, J.M.W.5
De Leeuw, P.W.6
De Bruin, T.W.A.7
-
133
-
-
75149145515
-
Identification of two common variants contributing to serum apolipoprotein B levels in Mexicans
-
Weissglas-Volkov, D. et al. Identification of two common variants contributing to serum apolipoprotein B levels in Mexicans. Arterioscler. Thromb. Vasc. Biol. 30, 353-359 (2010).
-
(2010)
Arterioscler. Thromb. Vasc. Biol.
, vol.30
, pp. 353-359
-
-
Weissglas-Volkov, D.1
-
134
-
-
34248197888
-
Association of a polymorphism in the promoter of the cellular retinoic acid-binding protein II gene (CRABP2) with increased circulating low-density lipoprotein cholesterol
-
DOI 10.1515/CCLM.2007.131
-
Salazar, J. et al. Association of a polymorphism in the promoter of the cellular retinoic acid-binding protein II gene (CRABP2) with increased circulating low-density lipoprotein cholesterol. Clin. Chem. Lab. Med. 45, 615-620 (2007). (Pubitemid 46709753)
-
(2007)
Clinical Chemistry and Laboratory Medicine
, vol.45
, Issue.5
, pp. 615-620
-
-
Salazar, J.1
Guardiola, M.2
Ferre, R.3
Coll, B.4
Alonso-Villaverde, C.5
Winklhofer-Roob, B.M.6
Rock, E.7
Fernandez-Ballart, J.D.8
Civeira, F.9
Pocovi, M.10
Masana, L.11
Ribalta, J.12
-
135
-
-
58849095360
-
Galanin preproprotein is associated with elevated plasma triglycerides
-
Plaisier, C. L. et al. Galanin preproprotein is associated with elevated plasma triglycerides. Arterioscler. Thromb. Vasc. Biol. 29, 147-152 (2009).
-
(2009)
Arterioscler. Thromb. Vasc. Biol.
, vol.29
, pp. 147-152
-
-
Plaisier, C.L.1
-
136
-
-
77953053518
-
Specification of arterial, venous, and lymphatic endothelial cells during embryonic development
-
Kume, T. Specification of arterial, venous, and lymphatic endothelial cells during embryonic development. Histol. Histopathol. 25, 637-646 (2010).
-
(2010)
Histol. Histopathol.
, vol.25
, pp. 637-646
-
-
Kume, T.1
-
137
-
-
79952267887
-
Neuroprotective role for galanin in Alzheimer's disease
-
Counts, S. E., Perez, S. E., Ginsberg, S. D. & Mufson, E. J. Neuroprotective role for galanin in Alzheimer's disease. EXS 102, 143-162 (2010).
-
(2010)
EXS
, vol.102
, pp. 143-162
-
-
Counts, S.E.1
Perez, S.E.2
Ginsberg, S.D.3
Mufson, E.J.4
-
138
-
-
44849099288
-
Association of stearoyl-CoA desaturase 1 activity with familial combined hyperlipidemia
-
Mar-Heyming, R. et al. Association of stearoyl-CoA desaturase 1 activity with familial combined hyperlipidemia. Arterioscler. Thromb. Vasc. Biol. 28, 1193-1199 (2008).
-
(2008)
Arterioscler. Thromb. Vasc. Biol.
, vol.28
, pp. 1193-1199
-
-
Mar-Heyming, R.1
-
139
-
-
18344386779
-
Genome scans provide evidence for low-HDL-C loci on chromosomes 8q23, 16q24.1-24.2, and 20q13.11 in Finnish families
-
DOI 10.1086/339988
-
Soro, A. et al. Genome scans provide evidence for low-HDL-C loci on chromosomes 8q23, 16q24.1-242, and 20q13.11 in Finnish families. Am. J. Hum. Genet. 70, 1333-1340 (2002). (Pubitemid 34450583)
-
(2002)
American Journal of Human Genetics
, vol.70
, Issue.5
, pp. 1333-1340
-
-
Soro, A.1
Pajukanta, P.2
Lilja, H.E.3
Ylitalo, K.4
Hiekkalinna, T.5
Perola, M.6
Cantor, R.M.7
Viikari, J.S.A.8
Taskinen, M.-R.9
Peltonen, L.10
-
140
-
-
80053202844
-
Linkage and association of phospholipid transfer protein activity to LASS4
-
Rosenthal, E. A. et al. Linkage and association of phospholipid transfer protein activity to LASS4. J. Lipid Res. 52, 1837-1846 (2011).
-
(2011)
J. Lipid Res.
, vol.52
, pp. 1837-1846
-
-
Rosenthal, E.A.1
-
141
-
-
77449139212
-
A nonsynonymous SNP within PCDH15 is associated with lipid traits in familial combined hyperlipidemia
-
Huertas-Vazquez, A. et al. A nonsynonymous SNP within PCDH15 is associated with lipid traits in familial combined hyperlipidemia. Hum. Genet. 127, 83-89 (2010).
-
(2010)
Hum. Genet.
, vol.127
, pp. 83-89
-
-
Huertas-Vazquez, A.1
-
142
-
-
11844265021
-
Locus for quantitative HDL-cholesterol on chromosome 10q in Finnish families with dyslipidemia
-
DOI 10.1194/jlr.M400141-JLR200
-
Lilja, H. E. et al. Locus for quantitative HDL-cholesterol on chromosome 10q in Finnish families with dyslipidemia. J. Lipid Res. 45, 1876-1884 (2004).
-
(2004)
Journal of Lipid Research
, vol.45
, Issue.10
, pp. 1876-1884
-
-
Lilja, H.E.1
Suviolahti, E.2
Soro-Paavonen, A.3
Hiekkalinna, T.4
Day, A.5
Lange, K.6
Sobel, E.7
Taskinen, M.-R.8
Peltonen, L.9
Perola, M.10
Pajukanta, P.11
-
143
-
-
45449106652
-
Paraoxonase (PON1) is associated with familial combined hyperlipidemia
-
van Himbergen, T. M. et al. Paraoxonase (PON1) is associated with familial combined hyperlipidemia. Atherosclerosis 199, 87-94 (2008).
-
(2008)
Atherosclerosis
, vol.199
, pp. 87-94
-
-
Van Himbergen, T.M.1
-
144
-
-
3042638495
-
Associations between HDL oxidation and paraoxonase-1 and paraoxonase-1 gene polymorphisms in families affected by familial combined hyperlipidemia
-
DOI 10.1016/S0939-4753(04)80014-0
-
Liu, M. L., James, R. W., Ylitalo, K. & Taskinen, M. R. Associations between HDL oxidation and paraoxonase-1 and paraoxonase-1 gene polymorphisms in families affected by familial combined hyperlipidemia. Nutr. Metab. Cardiovasc. Dis. 14, 81-87 (2004). (Pubitemid 38813708)
-
(2004)
Nutrition, Metabolism and Cardiovascular Diseases
, vol.14
, Issue.2
, pp. 81-87
-
-
Liu, M.-L.1
James, R.W.2
Ylitalo, K.3
Taskinen, M.-R.4
-
145
-
-
36649027501
-
TCF7L2 is associated with high serum triacylglycerol and differentially expressed in adipose tissue in families with familial combined hyperlipidaemia
-
DOI 10.1007/s00125-007-0850-6
-
Huertas-Vazquez, A. et al. TCF7L2 is associated with high serum triacylglycerol and differentially expressed in adipose tissue in families with familial combined hyperlipidaemia. Diabetologia 51, 62-69 (2008). (Pubitemid 50000014)
-
(2008)
Diabetologia
, vol.51
, Issue.1
, pp. 62-69
-
-
Huertas-Vazquez, A.1
Plaisier, C.2
Weissglas-Volkov, D.3
Sinsheimer, J.4
Canizales-Quinteros, S.5
Cruz-Bautista, I.6
Nikkola, E.7
Herrera-Hernandez, M.8
Davila-Cervantes, A.9
Tusie-Luna, T.10
Taskinen, M.-R.11
Aguilar-Salinas, C.12
Pajukanta, P.13
-
146
-
-
76749084749
-
Prioritizing genes for follow-up from genome wide association studies using information on gene expression in tissues relevant for type 2 diabetes mellitus
-
Parikh, H., Lyssenko, V. & Groop, L. C. Prioritizing genes for follow-up from genome wide association studies using information on gene expression in tissues relevant for type 2 diabetes mellitus. BMC Med. Genomics 2, 72 (2009).
-
(2009)
BMC Med. Genomics
, vol.2
, pp. 72
-
-
Parikh, H.1
Lyssenko, V.2
Groop, L.C.3
-
147
-
-
33847117670
-
Tumor necrosis factor-α receptor p75 is required in ischemia-induced neovascularization
-
DOI 10.1161/CIRCULATIONAHA.106.647255, PII 0000301720070213000013
-
Goukassian, D. A. et al. Tumor necrosis factor-α receptor p75 is required in ischemia-induced neovascularization. Circulation 115, 752-762 (2007). (Pubitemid 46294766)
-
(2007)
Circulation
, vol.115
, Issue.6
, pp. 752-762
-
-
Goukassian, D.A.1
Qin, G.2
Dolan, C.3
Murayama, T.4
Silver, M.5
Curry, C.6
Eaton, E.7
Luedemann, C.8
Ma, H.9
Asahara, T.10
Zak, V.11
Mehta, S.12
Burg, A.13
Thorne, T.14
Kishore, R.15
Losordo, D.W.16
-
148
-
-
30744461133
-
TNF receptor type 2 (p75) functions as a costimulator for antigen-driven T cell responses in vivo
-
Kim, E. Y., Priatel, J. J., Teh, S. J. & Teh, H. S. TNF receptor type 2 (p75) functions as a costimulator for antigen-driven T cell responses in vivo. J. Immunol. 176, 1026-1035 (2006). (Pubitemid 43099703)
-
(2006)
Journal of Immunology
, vol.176
, Issue.2
, pp. 1026-1035
-
-
Kim, E.Y.1
Priatel, J.J.2
Teh, S.-J.3
Teh, H.-S.4
-
149
-
-
0034284684
-
Identification of TNFRSF1B as a novel modifier gene in familial combined hyperlipidemia
-
Geurts, J. M. et al. Identification of TNFRSF1B as a novel modifier gene in familial combined hyperlipidemia. Hum. Mol. Genet. 9, 2067-2074 (2000).
-
(2000)
Hum. Mol. Genet.
, vol.9
, pp. 2067-2074
-
-
Geurts, J.M.1
-
150
-
-
77957818072
-
WWOX gene is associated with HDL cholesterol and triglyceride levels
-
Sáez, M. E. et al. WWOX gene is associated with HDL cholesterol and triglyceride levels. BMC Med. Genet. 11, 148 (2010).
-
(2010)
BMC Med. Genet.
, vol.11
, Issue.148
-
-
Sáez, M.E.1
|