메뉴 건너뛰기




Volumn 38, Issue 6, 1997, Pages 1061-1069

A variation in the apolipoprotein C-III gene is associated with an increased number of circulating VLDL and IDL particles in familial combined hyperlipidemia

Author keywords

A I C III A IV gene cluster; CAD; Genetic marker; Genotype status interaction; Metabolic syndrome; Predisposition; Remnant particles

Indexed keywords

APOLIPOPROTEIN C; INTERMEDIATE DENSITY LIPOPROTEIN; VERY LOW DENSITY LIPOPROTEIN;

EID: 0030978794     PISSN: 00222275     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (40)

References (35)
  • 1
    • 0015579930 scopus 로고
    • Inheritance of combined hyperlipoproteinemia: Evidence for a new lipoprotein phenotype
    • Rose, H. G., P. Kranz, M. Weinstock, J. Juliano, and J. I. Haft. 1973. Inheritance of combined hyperlipoproteinemia: evidence for a new lipoprotein phenotype. Am. J. Med. 54: 148-160.
    • (1973) Am. J. Med. , vol.54 , pp. 148-160
    • Rose, H.G.1    Kranz, P.2    Weinstock, M.3    Juliano, J.4    Haft, J.I.5
  • 2
    • 0015796295 scopus 로고
    • Hyperlipidaemia in coronary heart disease. II. Genetic analysis of lipid levels in 176 families and delineation of a new inherited disorder, combined hyperlipidaemia
    • Goldstein, J. L., H. G. Schrott, W. R. Hazzard, E. L. Bierman, and A. G. Motulsky. 1973. Hyperlipidaemia in coronary heart disease. II. Genetic analysis of lipid levels in 176 families and delineation of a new inherited disorder, combined hyperlipidaemia. J. Clin. Invest. 52: 1544-1568.
    • (1973) J. Clin. Invest. , vol.52 , pp. 1544-1568
    • Goldstein, J.L.1    Schrott, H.G.2    Hazzard, W.R.3    Bierman, E.L.4    Motulsky, A.G.5
  • 3
    • 0027415567 scopus 로고
    • Genetics and molecular biology of familial combined hyperlipidemia
    • Kwiterovich, P. O., Jr. 1993. Genetics and molecular biology of familial combined hyperlipidemia. Curr. Opin. Lipidol. 4: 133-143.
    • (1993) Curr. Opin. Lipidol. , vol.4 , pp. 133-143
    • Kwiterovich Jr., P.O.1
  • 5
    • 0023237538 scopus 로고
    • Familial combined hyperlipidemia workshop
    • Grundy, S. M., A. Chait, and J. D. Brunzell. 1987. Familial combined hyperlipidemia workshop. Arteriosclerosis. 7: 203-207.
    • (1987) Arteriosclerosis , vol.7 , pp. 203-207
    • Grundy, S.M.1    Chait, A.2    Brunzell, J.D.3
  • 6
    • 0025374073 scopus 로고
    • Prevalence and expression of familial combined hyperlipidemia in childhood
    • Cortner, J. A., P. M. Coates, and P. R. Gallagher. 1990. Prevalence and expression of familial combined hyperlipidemia in childhood. J. Pediatr. 116: 514-519.
    • (1990) J. Pediatr. , vol.116 , pp. 514-519
    • Cortner, J.A.1    Coates, P.M.2    Gallagher, P.R.3
  • 7
    • 0020621407 scopus 로고
    • Plasma lipoproteins in familial combined hyperlipidemia and monogenic familial hypertriglyceridemia
    • Brunzell, J. D., J. J. Albers, A. Chait, S. M. Grundy, E. Groszek, and G. B. Mc Donald. 1983. Plasma lipoproteins in familial combined hyperlipidemia and monogenic familial hypertriglyceridemia. J. Lipid Res. 24: 147-155.
    • (1983) J. Lipid Res. , vol.24 , pp. 147-155
    • Brunzell, J.D.1    Albers, J.J.2    Chait, A.3    Grundy, S.M.4    Groszek, E.5    McDonald, G.B.6
  • 8
    • 0015914934 scopus 로고
    • Family study of serum lipids and lipoproteins in coronary heart disease
    • Nikkilä, E. A., and A. Aro. 1973. Family study of serum lipids and lipoproteins in coronary heart disease. Lancet. 1: 954-959.
    • (1973) Lancet , vol.1 , pp. 954-959
    • Nikkilä, E.A.1    Aro, A.2
  • 9
    • 0018843763 scopus 로고
    • Very low density lipoprotein overproduction in genetic forms of hypertriglyceridemia
    • Chait, A., J. J. Albers, and J. D. Brunzell. 1980. Very low density lipoprotein overproduction in genetic forms of hypertriglyceridemia. Eur. J. Clin. Invest. 10: 17-22.
    • (1980) Eur. J. Clin. Invest. , vol.10 , pp. 17-22
    • Chait, A.1    Albers, J.J.2    Brunzell, J.D.3
  • 10
    • 0025999972 scopus 로고
    • Familial combined hyperlipidemia: Use of stable isotopes to demonstrate overproduction of very-low-density lipoprotein apolipoprotein B by the liver
    • Cortner, J. A., P. M. Coates, M. J. Bennett, D. R. Cryer, and N. A. Le. 1991. Familial combined hyperlipidemia: use of stable isotopes to demonstrate overproduction of very-low-density lipoprotein apolipoprotein B by the liver. J. Inherited Dis. 14: 915-922.
    • (1991) J. Inherited Dis. , vol.14 , pp. 915-922
    • Cortner, J.A.1    Coates, P.M.2    Bennett, M.J.3    Cryer, D.R.4    Le, N.A.5
  • 11
    • 0018886617 scopus 로고
    • Kinetic bases of the primary hyperlipidemias: Studies of apolipoprotein B turnover in genetically defined subjects
    • Janus, E. D., A. M. Nicoll, P. R. Turner, P. Magill, and B. Lewis. 1980. Kinetic bases of the primary hyperlipidemias: studies of apolipoprotein B turnover in genetically defined subjects. Eur. J. Clin. Invest. 10: 161-172.
    • (1980) Eur. J. Clin. Invest. , vol.10 , pp. 161-172
    • Janus, E.D.1    Nicoll, A.M.2    Turner, P.R.3    Magill, P.4    Lewis, B.5
  • 12
    • 0027322479 scopus 로고
    • Stable isotopes show a direct relation between VLDL apoB overproduction and serum triglyceride levels and indicate a metabolically and biochemically coherent basis for familial combined hyperlipidemia
    • Venkatesan, S., P. Cullen, P. Pacy, D. Halliday, and J. Scott. 1993. Stable isotopes show a direct relation between VLDL apoB overproduction and serum triglyceride levels and indicate a metabolically and biochemically coherent basis for familial combined hyperlipidemia. Arterioscler. Thromb. 13: 1110-1118.
    • (1993) Arterioscler. Thromb. , vol.13 , pp. 1110-1118
    • Venkatesan, S.1    Cullen, P.2    Pacy, P.3    Halliday, D.4    Scott, J.5
  • 13
    • 0025302745 scopus 로고
    • Genetic evidence from 7 families that the apoB gene is not involved in familial combined hyperlipidemia
    • Raugh, G., H. Schuster, B. Müller, S. Schewe, C. Keller, G. Wolfram, and N. Zöllner. 1990. Genetic evidence from 7 families that the apoB gene is not involved in familial combined hyperlipidemia. Atherosclerosis. 83: 81-87.
    • (1990) Atherosclerosis , vol.83 , pp. 81-87
    • Raugh, G.1    Schuster, H.2    Müller, B.3    Schewe, S.4    Keller, C.5    Wolfram, G.6    Zöllner, N.7
  • 14
    • 0026341578 scopus 로고
    • Lack of evidence for linkage between low-density lipoprotein subclass phenotypes and the apolipoprotein B locus in familial combined hyperlipidemia
    • Austin, M. A., E. Wijsman, S. W. Guo, R. M. Krauss, J. D. Brunzell, and S. Deeb. 1991. Lack of evidence for linkage between low-density lipoprotein subclass phenotypes and the apolipoprotein B locus in familial combined hyperlipidemia. Genet. Epidemiol. 8: 287-297.
    • (1991) Genet. Epidemiol. , vol.8 , pp. 287-297
    • Austin, M.A.1    Wijsman, E.2    Guo, S.W.3    Krauss, R.M.4    Brunzell, J.D.5    Deeb, S.6
  • 15
    • 0022971151 scopus 로고
    • Apolipoprotein B metabolism in subjects with deficiency of apolipoprotein C-III and A-I: Evidence that apolipoprotein C-III inhibits catabolism of triglyceride-rich lipoproteins by lipoprotein lipase in vivo
    • Ginsberg, H. N., N. A. Le, I. J. Goldberg, J. C. Gibson, A. Rubinstein, P. Wang-Iverson, R. Norum, and V. W. Brown. 1986. Apolipoprotein B metabolism in subjects with deficiency of apolipoprotein C-III and A-I: evidence that apolipoprotein C-III inhibits catabolism of triglyceride-rich lipoproteins by lipoprotein lipase in vivo. J. Clin. Invest. 8: 1287-1295.
    • (1986) J. Clin. Invest. , vol.8 , pp. 1287-1295
    • Ginsberg, H.N.1    Le, N.A.2    Goldberg, I.J.3    Gibson, J.C.4    Rubinstein, A.5    Wang-Iverson, P.6    Norum, R.7    Brown, V.W.8
  • 16
    • 0015530365 scopus 로고
    • Inhibition of lipoprotein lipase by an apolipoprotein of human very low density lipoprotein
    • Brown, W. V., and M. L. Baginsky. 1972. Inhibition of lipoprotein lipase by an apolipoprotein of human very low density lipoprotein. Biochem. Biophys. Res. Commun. 46: 375-382.
    • (1972) Biochem. Biophys. Res. Commun. , vol.46 , pp. 375-382
    • Brown, W.V.1    Baginsky, M.L.2
  • 17
    • 0027099736 scopus 로고
    • Lipoprotein lipase: Recent contributions from molecular biology
    • Auwerx, J., P. Leroy, and K. Schoonjans. 1992. Lipoprotein lipase: recent contributions from molecular biology. Crit. Rev. Cl. Lab. Sci. 3,4: 243-268.
    • (1992) Crit. Rev. Cl. Lab. Sci. , vol.3-4 , pp. 243-268
    • Auwerx, J.1    Leroy, P.2    Schoonjans, K.3
  • 18
    • 0026012340 scopus 로고
    • Lipoprotein lipase regulates net secretory output of apolipoprotein B in vitro: A possible pathophysiologic explanation for familial combined hyperlipidemia
    • Williams, K. J., K. A. Petrie, R. W. Brocia, and T. L. Swenson. 1991. Lipoprotein lipase regulates net secretory output of apolipoprotein B in vitro: a possible pathophysiologic explanation for familial combined hyperlipidemia. J. Clin. Invest. 88: 1300-1306.
    • (1991) J. Clin. Invest. , vol.88 , pp. 1300-1306
    • Williams, K.J.1    Petrie, K.A.2    Brocia, R.W.3    Swenson, T.L.4
  • 19
    • 0028069690 scopus 로고
    • Overexpression of human apolipoprotein C-III in transgenic mice results in an accumulation of apolipoprotein B48 remnants that is corrected by excess apolipoprotein e
    • De Silva, H. V., S. J. Lauer, J. Wang, W. S. Simonet, K. H. Weisgraber, R. W. Mahley, and J. M. Taylor. 1994. Overexpression of human apolipoprotein C-III in transgenic mice results in an accumulation of apolipoprotein B48 remnants that is corrected by excess apolipoprotein E. J. Biol. Chem. 269: 2324-2335.
    • (1994) J. Biol. Chem. , vol.269 , pp. 2324-2335
    • De Silva, H.V.1    Lauer, S.J.2    Wang, J.3    Simonet, W.S.4    Weisgraber, K.H.5    Mahley, R.W.6    Taylor, J.M.7
  • 21
    • 0025030698 scopus 로고
    • Hypertriglyceridemia as a result of human apoC-III gene expression in transgenic mice
    • Ito, Y., N. Azrolan, A. O'Connell, A. Walsh, and J. L. Breslow. 1990. Hypertriglyceridemia as a result of human apoC-III gene expression in transgenic mice. Science. 249: 790-793.
    • (1990) Science , vol.249 , pp. 790-793
    • Ito, Y.1    Azrolan, N.2    O'Connell, A.3    Walsh, A.4    Breslow, J.L.5
  • 23
    • 0025871435 scopus 로고
    • Influence of apolipoproteins on the anatomical distribution of arterial disease
    • Wiseman, S., J. T. Powell, N. Barber, S. E. Humphries, and R. M. Greenhalgh. 1991. Influence of apolipoproteins on the anatomical distribution of arterial disease. Atherosclerosis. 89: 231-237.
    • (1991) Atherosclerosis , vol.89 , pp. 231-237
    • Wiseman, S.1    Powell, J.T.2    Barber, N.3    Humphries, S.E.4    Greenhalgh, R.M.5
  • 24
    • 0025055322 scopus 로고
    • Prediction of angiographic change in native human coronary arteries and aortocoronary bypass grafts
    • Blankenhorn, D. H., P. Alaupovic, E. Wickmaam, H. P. Chin, and S. P. Azen. 1990. Prediction of angiographic change in native human coronary arteries and aortocoronary bypass grafts. Circulation. 81: 470-476.
    • (1990) Circulation , vol.81 , pp. 470-476
    • Blankenhorn, D.H.1    Alaupovic, P.2    Wickmaam, E.3    Chin, H.P.4    Azen, S.P.5
  • 25
    • 0022374261 scopus 로고
    • A study of DNA polymorphisms around the human apolipoprotein A-I gene in hyperlipidemic and normal individuals
    • Kessling, A. M., B. Horsthemke, and S. E. Humphries. 1985. A study of DNA polymorphisms around the human apolipoprotein A-I gene in hyperlipidemic and normal individuals. Clin. Genet. 28: 296-306.
    • (1985) Clin. Genet. , vol.28 , pp. 296-306
    • Kessling, A.M.1    Horsthemke, B.2    Humphries, S.E.3
  • 27
    • 0028559791 scopus 로고
    • Association between genetic variation at the apoAI-CIII-AIV gene cluster and familial combined hyperlipidemia
    • Xu, C. F., P. Talmud, H. Schuster, R. Houlston, G. Miller, and S. Humphries. 1994. Association between genetic variation at the apoAI-CIII-AIV gene cluster and familial combined hyperlipidemia. Clin. Genet. 46: 385-397.
    • (1994) Clin. Genet. , vol.46 , pp. 385-397
    • Xu, C.F.1    Talmud, P.2    Schuster, H.3    Houlston, R.4    Miller, G.5    Humphries, S.6
  • 28
    • 0030069735 scopus 로고    scopus 로고
    • Apolipoprotein A-I/C-III/A-IV gene cluster in familial combined hyperlipidemia: Effects on LDL-cholesterol and apolipoproteins B and C-III
    • Dallinga-Thie, G. M., X-D. Bu, M. v L-S. Trip, J. I. Rotter, A. J. Lusis, and T. W. A. de Bruin. 1996. Apolipoprotein A-I/C-III/A-IV gene cluster in familial combined hyperlipidemia: effects on LDL-cholesterol and apolipoproteins B and C-III. J. Lipid Res. 37: 136-147.
    • (1996) J. Lipid Res. , vol.37 , pp. 136-147
    • Dallinga-Thie, G.M.1    Bu, X.-D.2    Trip, M.V.L.-S.3    Rotter, J.I.4    Lusis, A.J.5    De Bruin, T.W.A.6
  • 29
    • 0022556074 scopus 로고
    • Sequential flotation ultracentrifugation
    • Schumaker, V. R., and D. L. Puppione. 1986. Sequential flotation ultracentrifugation. Methods Enzymol. 128: 155-170.
    • (1986) Methods Enzymol. , vol.128 , pp. 155-170
    • Schumaker, V.R.1    Puppione, D.L.2
  • 30
    • 0024284028 scopus 로고
    • A simple salting out method procedure for extracting DNA from human nucleated cells
    • Miller, S. A., D. D. Dykes, and H. F. Polesky. 1988. A simple salting out method procedure for extracting DNA from human nucleated cells. Nucleic Acids Res. 16: 1215.
    • (1988) Nucleic Acids Res. , vol.16 , pp. 1215
    • Miller, S.A.1    Dykes, D.D.2    Polesky, H.F.3
  • 31
    • 0027944709 scopus 로고
    • Three new polymorphisms of the apoAI-CIII-ATV gene cluster
    • Xu, C. F., P. Talmud, and S. E. Humphries. 1994. Three new polymorphisms of the apoAI-CIII-ATV gene cluster. Mol. Cell. Probes. 8: 331-332.
    • (1994) Mol. Cell. Probes. , vol.8 , pp. 331-332
    • Xu, C.F.1    Talmud, P.2    Humphries, S.E.3
  • 35
    • 0027223301 scopus 로고
    • An apolipoprotein C-III haplotype protective against hypertriglyceridemia is specified by promoter and 3′ untranslated polymorphisms
    • Dammerman, M., L. A. Sandkuijl, J. L. Halaas, and J. L. Breslow. 1993. An apolipoprotein C-III haplotype protective against hypertriglyceridemia is specified by promoter and 3′ untranslated polymorphisms. Proc. Natl. Acad. Sci. USA. 90: 4562-4566.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 4562-4566
    • Dammerman, M.1    Sandkuijl, L.A.2    Halaas, J.L.3    Breslow, J.L.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.