메뉴 건너뛰기




Volumn 21, Issue 2, 2006, Pages 63-85

What Is New in Cytokine Research Related to Trauma/Critical Care

Author keywords

cytokine; interleukin; review; sepsis; trauma

Indexed keywords

CYTOKINE; INTERLEUKIN DERIVATIVE; TUMOR NECROSIS FACTOR ALPHA;

EID: 33746396118     PISSN: 08850666     EISSN: None     Source Type: Journal    
DOI: 10.1177/0885066605284325     Document Type: Review
Times cited : (30)

References (81)
  • 1
    • 0033546597 scopus 로고    scopus 로고
    • Genetic factors in septic shock
    • Kumar A, Short J, Parrillo J. Genetic factors in septic shock. JAMA. 1999;282:579-581.
    • (1999) JAMA , vol.282 , pp. 579-581
    • Kumar, A.1    Short, J.2    Parrillo, J.3
  • 2
    • 0036250922 scopus 로고    scopus 로고
    • The era of genomics: impact on sepsis clinical trial design
    • Cariou A, Chiche JD, Charpentier J, et al. The era of genomics: impact on sepsis clinical trial design. Crit Care Med. 2002;30 (suppl): S341-S348.
    • (2002) Crit Care Med , vol.30 , pp. S341-S348
    • Cariou, A.1    Chiche, J.D.2    Charpentier, J.3
  • 3
    • 0037253163 scopus 로고    scopus 로고
    • Influence of interleukin-10 polymorphisms on interleukin-10 expression and survival in critically ill patients
    • Lowe P, Galley H, Abdel-Fattah A, Webster N. Influence of interleukin-10 polymorphisms on interleukin-10 expression and survival in critically ill patients. Crit Care Med.2003;31:34-38.
    • (2003) Crit Care Med , vol.31 , pp. 34-38
    • Lowe, P.1    Galley, H.2    Abdel-Fattah, A.3    Webster, N.4
  • 4
    • 9344249049 scopus 로고    scopus 로고
    • Differential distribution of allelic variants in cytokine genes among African Americans and White Americans
    • Ness, R, Haggerty C, Harger G, Ferrell R. Differential distribution of allelic variants in cytokine genes among African Americans and White Americans. Am J Epidemiol.2004;160:1033-1038.
    • (2004) Am J Epidemiol , vol.160 , pp. 1033-1038
    • Ness, R.1    Haggerty, C.2    Harger, G.3    Ferrell, R.4
  • 5
    • 0038047591 scopus 로고    scopus 로고
    • Methodologic quality and genotyping reproducibility in studies of tumor necrosis factor -308 G-A single nucleotide polymorphism and bacterial sepsis: implications for studies of complex traits
    • Peters DL, Barber RC, Flood EM, et al. Methodologic quality and genotyping reproducibility in studies of tumor necrosis factor -308 G-A single nucleotide polymorphism and bacterial sepsis: implications for studies of complex traits. Crit Care Med. 2003;31:1691-1696.
    • (2003) Crit Care Med , vol.31 , pp. 1691-1696
    • Peters, D.L.1    Barber, R.C.2    Flood, E.M.3
  • 6
    • 0032997973 scopus 로고    scopus 로고
    • Cytokines and anticytokines in the pathogenesis of sepsis
    • ix
    • van der Poll, T., van Deventer, S. Cytokines and anticytokines in the pathogenesis of sepsis. Infect Dis Clin North Am. 1999;13:413-426, ix.
    • (1999) Infect Dis Clin North Am , vol.13 , pp. 413-426
    • van der Poll, T.1    van Deventer, S.2
  • 7
    • 2542460201 scopus 로고    scopus 로고
    • Cytokines in patients with polytrauma
    • DeLong W, Born C. Cytokines in patients with polytrauma. Clin Orthop Rel Res. 2004;1:57-65.
    • (2004) Clin Orthop Rel Res , vol.1 , pp. 57-65
    • DeLong, W.1    Born, C.2
  • 8
    • 0346992046 scopus 로고    scopus 로고
    • Clinical trial design and outcomes in patients with severe sepsis
    • Opal SM. Clinical trial design and outcomes in patients with severe sepsis. Shock. 2003;20:295-302.
    • (2003) Shock , vol.20 , pp. 295-302
    • Opal, S.M.1
  • 9
    • 0033962077 scopus 로고    scopus 로고
    • Inflammatory cytokines and cell response in surgery
    • Lin E, Calvano SE, Lowry SF. Inflammatory cytokines and cell response in surgery. Surgery. 2000;127:117-126.
    • (2000) Surgery , vol.127 , pp. 117-126
    • Lin, E.1    Calvano, S.E.2    Lowry, S.F.3
  • 10
    • 0036711634 scopus 로고    scopus 로고
    • Decreased cytokine expression in peripheral blood leukocytes of patients with severe sepsis
    • Cabioglu N, Bilgic S, Deniz G, et al. Decreased cytokine expression in peripheral blood leukocytes of patients with severe sepsis. Arch Surg. 2002;137:1037-1043.
    • (2002) Arch Surg , vol.137 , pp. 1037-1043
    • Cabioglu, N.1    Bilgic, S.2    Deniz, G.3
  • 11
    • 0034893790 scopus 로고    scopus 로고
    • Clinical relevance of caspase-1 activated cytokines in acute pancreatitis: high correlation of serum interleukin-18 with pancreatic necrosis and systemic complications
    • Rau B, Baumgart K, Paszkowski AS, et al. Clinical relevance of caspase-1 activated cytokines in acute pancreatitis: high correlation of serum interleukin-18 with pancreatic necrosis and systemic complications. Crit Care Med. 2001;29:1556-1562.
    • (2001) Crit Care Med , vol.29 , pp. 1556-1562
    • Rau, B.1    Baumgart, K.2    Paszkowski, A.S.3
  • 12
    • 84992818102 scopus 로고    scopus 로고
    • ELISA Systems for the rapid quantitation of total human IL12 and human IL12 p70
    • Schonhorn J, Sharma H, Pritchard, J. ELISA Systems for the rapid quantitation of total human IL12 and human IL12 p70. J Allergy Clin Immunol. 1997;99:314.
    • (1997) J Allergy Clin Immunol , vol.99 , pp. 314
    • Schonhorn, J.1    Sharma, H.2    Pritchard, J.3
  • 13
    • 84992849789 scopus 로고    scopus 로고
    • An enzyme-linked immunosorbent assay (ELISA) for the measurement of human interleukin-8 (hIL-8) in serum, plasma and tissue culture fluids
    • Sullivan MD, Liponis T, Durda P, Pritchard J. An enzyme-linked immunosorbent assay (ELISA) for the measurement of human interleukin-8 (hIL-8) in serum, plasma and tissue culture fluids. J Allergy Clin Immunol. 1997;99:314.
    • (1997) J Allergy Clin Immunol , vol.99 , pp. 314
    • Sullivan, M.D.1    Liponis, T.2    Durda, P.3    Pritchard, J.4
  • 14
    • 0033862716 scopus 로고    scopus 로고
    • Interleukin-6 and tumor necrosis factor-alpha production after acute psychological stress, exercise, and infused isoproterenol: differential effects and pathways
    • Goebel MU, Mills PJ, Irwin MR, Ziegler MG. Interleukin-6 and tumor necrosis factor-alpha production after acute psychological stress, exercise, and infused isoproterenol: differential effects and pathways. Psychosom Med.2000;62:591-598.
    • (2000) Psychosom Med , vol.62 , pp. 591-598
    • Goebel, M.U.1    Mills, P.J.2    Irwin, M.R.3    Ziegler, M.G.4
  • 15
    • 0030764204 scopus 로고    scopus 로고
    • Pharmacodynamics of subcutaneous recombinant human interleukin-10 in healthy volunteers
    • Huhn RD, Radwanski E, Gallo J, et al. Pharmacodynamics of subcutaneous recombinant human interleukin-10 in healthy volunteers. Clin Pharmacol Ther. 1997;62:171-180.
    • (1997) Clin Pharmacol Ther , vol.62 , pp. 171-180
    • Huhn, R.D.1    Radwanski, E.2    Gallo, J.3
  • 16
    • 0036035313 scopus 로고    scopus 로고
    • Stability of interleukin 6, soluble interleukin 6 receptor, interleukin 10 and CC16 in human serum
    • Kenis G, Teunissen C, De Jongh R, et al. Stability of interleukin 6, soluble interleukin 6 receptor, interleukin 10 and CC16 in human serum. Cytokine. 2002;19:228-235.
    • (2002) Cytokine , vol.19 , pp. 228-235
    • Kenis, G.1    Teunissen, C.2    De Jongh, R.3
  • 17
    • 0033004694 scopus 로고    scopus 로고
    • Capacity to produce cytokines during weight restoration in patients with anorexia nervosa
    • Nagata T, Tobitani W, Kiriike N, et al. Capacity to produce cytokines during weight restoration in patients with anorexia nervosa. Psychosom Med. 1999;6:371-377.
    • (1999) Psychosom Med , vol.6 , pp. 371-377
    • Nagata, T.1    Tobitani, W.2    Kiriike, N.3
  • 18
    • 0034990039 scopus 로고    scopus 로고
    • Total cytokine immunoassay: a more accurate method of cytokine measurement?
    • Malone D, Napolitano LM, Genuit T, et al. Total cytokine immunoassay: a more accurate method of cytokine measurement? J Trauma. 2001;50:821-825.
    • (2001) J Trauma , vol.50 , pp. 821-825
    • Malone, D.1    Napolitano, L.M.2    Genuit, T.3
  • 19
    • 0742304348 scopus 로고    scopus 로고
    • Compartmentalisation of cytokines and cytokine inhibitors in ventilator-associated pneumonia
    • Millo JL, Schultz MJ, Williams C, et al. Compartmentalisation of cytokines and cytokine inhibitors in ventilator-associated pneumonia. Intensive Care Med. 2004;30:68-74.
    • (2004) Intensive Care Med , vol.30 , pp. 68-74
    • Millo, J.L.1    Schultz, M.J.2    Williams, C.3
  • 20
    • 0035047370 scopus 로고    scopus 로고
    • Blunted erythropoietic response to anemia in multiply traumatized patients
    • Hobisch-Hagen P, Wiedermann F, Mayr A, et al. Blunted erythropoietic response to anemia in multiply traumatized patients. Crit Care Med. 2001;29:743-747.
    • (2001) Crit Care Med , vol.29 , pp. 743-747
    • Hobisch-Hagen, P.1    Wiedermann, F.2    Mayr, A.3
  • 21
    • 0041808747 scopus 로고    scopus 로고
    • Impaired production of interferon-gamma and tumor necrosis factor-alpha but not of interleukin 10 in whole blood of patients with sepsis
    • Rigato O, Salomao R. Impaired production of interferon-gamma and tumor necrosis factor-alpha but not of interleukin 10 in whole blood of patients with sepsis. Shock.2003;19:113-116.
    • (2003) Shock , vol.19 , pp. 113-116
    • Rigato, O.1    Salomao, R.2
  • 22
    • 0035377436 scopus 로고    scopus 로고
    • Differential release of interleukins 6, 8, and 10 in cerebrospinal fluid and plasma after traumatic brain injury
    • Maier B, Schwerdtfeger K, Mautes A, et al. Differential release of interleukins 6, 8, and 10 in cerebrospinal fluid and plasma after traumatic brain injury. Shock. 2001;15:421-426.
    • (2001) Shock , vol.15 , pp. 421-426
    • Maier, B.1    Schwerdtfeger, K.2    Mautes, A.3
  • 23
    • 0141800036 scopus 로고    scopus 로고
    • Genetic polymorphisms in sepsis and septic shock: role in prognosis and potential for therapy
    • Holmes CL, Russell JA, Walley KR. Genetic polymorphisms in sepsis and septic shock: role in prognosis and potential for therapy. Chest. 2003;124:1103-1115.
    • (2003) Chest , vol.124 , pp. 1103-1115
    • Holmes, C.L.1    Russell, J.A.2    Walley, K.R.3
  • 24
    • 0033498342 scopus 로고    scopus 로고
    • Relation of a TNF gene polymorphism to severe sepsis in trauma patients
    • Majetschak M, Flohe S, Obertacke U, et al. Relation of a TNF gene polymorphism to severe sepsis in trauma patients. Ann Surg. 1999;230:207-214.
    • (1999) Ann Surg , vol.230 , pp. 207-214
    • Majetschak, M.1    Flohe, S.2    Obertacke, U.3
  • 25
    • 0037805569 scopus 로고    scopus 로고
    • Association of a TNF[beta] gene polymorphism with complications after major abdominal operations
    • Riese J, Woerner K, Zimmermann P, et al. Association of a TNF[beta] gene polymorphism with complications after major abdominal operations. Shock. 2003;19:1-4.
    • (2003) Shock , vol.19 , pp. 1-4
    • Riese, J.1    Woerner, K.2    Zimmermann, P.3
  • 26
    • 0036843337 scopus 로고    scopus 로고
    • Tumor necrosis factor gene polymorphisms, leukocyte function, and sepsis susceptibility in blunt trauma patients
    • Majetschak M, Obertacke U, Schade FU, et al. Tumor necrosis factor gene polymorphisms, leukocyte function, and sepsis susceptibility in blunt trauma patients. Clin Diagn Lab Immunol. 2002;9:1205-1211.
    • (2002) Clin Diagn Lab Immunol , vol.9 , pp. 1205-1211
    • Majetschak, M.1    Obertacke, U.2    Schade, F.U.3
  • 27
    • 0141793041 scopus 로고    scopus 로고
    • Tumor necrosis factor gene polymorphism is associated with enhanced systemic inflammatory response and increased cardiopulmonary morbidity after cardiac surgery
    • Tomasdottir H, Hjartarson H, Ricksten A, et al. Tumor necrosis factor gene polymorphism is associated with enhanced systemic inflammatory response and increased cardiopulmonary morbidity after cardiac surgery. Anesth Analg. 2003;97:944-949.
    • (2003) Anesth Analg , vol.97 , pp. 944-949
    • Tomasdottir, H.1    Hjartarson, H.2    Ricksten, A.3
  • 28
    • 2042485524 scopus 로고    scopus 로고
    • Effect of the LT-[alpha] (+250 G/A) polymorphism on markers of inflammation and clinical outcome in critically ill patients
    • Rauchschwalbe S, Maseizik T, Mittelkotter U, et al. Effect of the LT-[alpha] (+250 G/A) polymorphism on markers of inflammation and clinical outcome in critically ill patients. J Trauma. 2004;56:815-822.
    • (2004) J Trauma , vol.56 , pp. 815-822
    • Rauchschwalbe, S.1    Maseizik, T.2    Mittelkotter, U.3
  • 29
    • 0027142556 scopus 로고
    • Cytokine patterns in patients after major vascular surgery, hemorrhagic shock, and severe blunt trauma. Relation with subsequent adult respiratory distress syndrome and multiple organ failure
    • Roumen RM, Hendriks T, van der Ven-Jongekrijg J, et al. Cytokine patterns in patients after major vascular surgery, hemorrhagic shock, and severe blunt trauma. Relation with subsequent adult respiratory distress syndrome and multiple organ failure. Ann Surg. 1993;218:769-776.
    • (1993) Ann Surg , vol.218 , pp. 769-776
    • Roumen, R.M.1    Hendriks, T.2    van der Ven-Jongekrijg, J.3
  • 30
    • 0035999585 scopus 로고    scopus 로고
    • Pneumonia in multiple injured patients: a prospective controlled trial on early prediction using clinical and immunological parameters
    • Andermahr J, Greb A, Hensler T, et al. Pneumonia in multiple injured patients: a prospective controlled trial on early prediction using clinical and immunological parameters. Inflamm Res. 2002;51:265-272.
    • (2002) Inflamm Res , vol.51 , pp. 265-272
    • Andermahr, J.1    Greb, A.2    Hensler, T.3
  • 31
    • 0035123382 scopus 로고    scopus 로고
    • Early detection of increased tumour necrosis factor alpha (TNFalpha) and soluble TNF receptor protein plasma levels after trauma reveals associations with the clinical course
    • Spielmann S, Kerner T, Ahlers O, et al. Early detection of increased tumour necrosis factor alpha (TNFalpha) and soluble TNF receptor protein plasma levels after trauma reveals associations with the clinical course. Acta Anaesthesiol Scand. 2001;45:364-370.
    • (2001) Acta Anaesthesiol Scand , vol.45 , pp. 364-370
    • Spielmann, S.1    Kerner, T.2    Ahlers, O.3
  • 32
    • 0036191449 scopus 로고    scopus 로고
    • Early IL-6 plasma concentrations correlate with severity of brain injury and pneumonia in brain-injured patients
    • Woiciechowsky C, Schoning B, Cobanov J, et al. Early IL-6 plasma concentrations correlate with severity of brain injury and pneumonia in brain-injured patients. J Trauma.2002;52:339-345.
    • (2002) J Trauma , vol.52 , pp. 339-345
    • Woiciechowsky, C.1    Schoning, B.2    Cobanov, J.3
  • 33
    • 13644267048 scopus 로고    scopus 로고
    • Changes in CSF S100B and cytokine concentrations in early-phase severe traumatic brain injury
    • Hayakata T, Shiozaki T, Tasaki O, et al. Changes in CSF S100B and cytokine concentrations in early-phase severe traumatic brain injury. Shock. 2004;22:102-107.
    • (2004) Shock , vol.22 , pp. 102-107
    • Hayakata, T.1    Shiozaki, T.2    Tasaki, O.3
  • 34
    • 0034895949 scopus 로고    scopus 로고
    • A multicenter, open-label, prospective, randomized, dose-ranging pharmacokinetic study of the anti-TNF-alpha antibody afelimomab in patients with sepsis syndrome
    • Gallagher J, Fisher C, Sherman B, et al. A multicenter, open-label, prospective, randomized, dose-ranging pharmacokinetic study of the anti-TNF-alpha antibody afelimomab in patients with sepsis syndrome. Intensive Care Med. 2001;27:1169-1178.
    • (2001) Intensive Care Med , vol.27 , pp. 1169-1178
    • Gallagher, J.1    Fisher, C.2    Sherman, B.3
  • 35
    • 0036798240 scopus 로고    scopus 로고
    • Genetic variation in pro-inflammatory and anti-inflammatory cytokine production in multiple organ dysfunction syndrome
    • Reid CL, Perrey C, Pravica V, et al. Genetic variation in pro-inflammatory and anti-inflammatory cytokine production in multiple organ dysfunction syndrome. Crit Care Med.2002;30:2216-2221.
    • (2002) Crit Care Med , vol.30 , pp. 2216-2221
    • Reid, C.L.1    Perrey, C.2    Pravica, V.3
  • 36
    • 0036169048 scopus 로고    scopus 로고
    • Evaluation of endotoxin release and cytokine production induced by antibiotics in patients with Gram-negative nosocomial pneumonia
    • Maskin B, Fontan PA, Spinedi EG, et al. Evaluation of endotoxin release and cytokine production induced by antibiotics in patients with Gram-negative nosocomial pneumonia. Crit Care Med. 2002;30:349-354.
    • (2002) Crit Care Med , vol.30 , pp. 349-354
    • Maskin, B.1    Fontan, P.A.2    Spinedi, E.G.3
  • 37
    • 0035100346 scopus 로고    scopus 로고
    • Lenercept (p55 tumor necrosis factor receptor fusion protein) in severe sepsis and early septic shock: a randomized, double-blind, placebo-controlled, multicenter phase III trial with 1,342 patients
    • Abraham E, Laterre PF, Garbino J, et al. Lenercept (p55 tumor necrosis factor receptor fusion protein) in severe sepsis and early septic shock: a randomized, double-blind, placebo-controlled, multicenter phase III trial with 1,342 patients. Crit Care Med. 2001;29:503-510.
    • (2001) Crit Care Med , vol.29 , pp. 503-510
    • Abraham, E.1    Laterre, P.F.2    Garbino, J.3
  • 38
    • 0035120112 scopus 로고    scopus 로고
    • North American Sepsis Trial II. The effect of aging on circulating levels of proinflammatory cytokines during septic shock. Norasept II Study Investigators
    • Marik PE, Zaloga GP, NORASEPT II Study Investigators. North American Sepsis Trial II. The effect of aging on circulating levels of proinflammatory cytokines during septic shock. Norasept II Study Investigators. J Am Geriatr Soc.2001;49:5-9.
    • (2001) J Am Geriatr Soc , vol.49 , pp. 5-9
    • Marik, P.E.1    Zaloga, G.P.2
  • 39
    • 0035259026 scopus 로고    scopus 로고
    • The value of immune modulating parameters in predicting the progression from peritonitis to septic shock
    • Katja B, Hartmut K, Pawel M, et al. The value of immune modulating parameters in predicting the progression from peritonitis to septic shock. Shock. 2001;15:95-100.
    • (2001) Shock , vol.15 , pp. 95-100
    • Katja, B.1    Hartmut, K.2    Pawel, M.3
  • 40
    • 0035141347 scopus 로고    scopus 로고
    • Role of interleukin-10 in monocyte hyporesponsiveness associated with septic shock
    • Sfeir T, Saha DC, Astiz M, Rackow EC. Role of interleukin-10 in monocyte hyporesponsiveness associated with septic shock. Crit Care Med. 2001;29:129-133.
    • (2001) Crit Care Med , vol.29 , pp. 129-133
    • Sfeir, T.1    Saha, D.C.2    Astiz, M.3    Rackow, E.C.4
  • 41
    • 0034904935 scopus 로고    scopus 로고
    • Macrophage migration inhibitory factor is a critical mediator of systemic inflammatory response syndrome
    • Gando S, Nishihira J, Kobayashi S, et al. Macrophage migration inhibitory factor is a critical mediator of systemic inflammatory response syndrome. Intensive Care Med.2001;27:1187-1193.
    • (2001) Intensive Care Med , vol.27 , pp. 1187-1193
    • Gando, S.1    Nishihira, J.2    Kobayashi, S.3
  • 42
    • 0036833427 scopus 로고    scopus 로고
    • Early postoperative compensatory anti-inflammatory response syndrome is associated with septic complications after major surgical trauma in patients with cancer
    • Mokart D, Capo C, Blache JL, et al. Early postoperative compensatory anti-inflammatory response syndrome is associated with septic complications after major surgical trauma in patients with cancer. Br J Surg. 2002;89:1450-1456.
    • (2002) Br J Surg , vol.89 , pp. 1450-1456
    • Mokart, D.1    Capo, C.2    Blache, J.L.3
  • 43
    • 0036188871 scopus 로고    scopus 로고
    • Response of tumour necrosis factor-alpha to delayed in vitro monocyte stimulation in patients with septic shock is related to outcome
    • Appoloni O, Vincent JL, Duchateau J. Response of tumour necrosis factor-alpha to delayed in vitro monocyte stimulation in patients with septic shock is related to outcome. Clin Sci (Lond). 2002;102:315-320.
    • (2002) Clin Sci (Lond) , vol.102 , pp. 315-320
    • Appoloni, O.1    Vincent, J.L.2    Duchateau, J.3
  • 44
    • 0142057054 scopus 로고    scopus 로고
    • Effect of granulocyte-macrophage colony-stimulating factor on the immune response of circulating monocytes after severe trauma
    • Flohe S, Lendemans S, Selbach C, et al. Effect of granulocyte-macrophage colony-stimulating factor on the immune response of circulating monocytes after severe trauma. Crit Care Med. 2003;31:2462-2469.
    • (2003) Crit Care Med , vol.31 , pp. 2462-2469
    • Flohe, S.1    Lendemans, S.2    Selbach, C.3
  • 45
    • 0034913364 scopus 로고    scopus 로고
    • Anti-tumor necrosis factor therapy in sepsis: update on clinical trials and lessons learned
    • Reinhart K, Karzai W. Anti-tumor necrosis factor therapy in sepsis: update on clinical trials and lessons learned. Crit Care Med. 2001;29(suppl): S121-S125.
    • (2001) Crit Care Med , vol.29 , pp. S121-S125
    • Reinhart, K.1    Karzai, W.2
  • 46
    • 0036840629 scopus 로고    scopus 로고
    • Risk and the efficacy of antiinflammatory agents: retrospective and confirmatory studies of sepsis
    • Eichacker PQ, Parent C, Kalil A, et al. Risk and the efficacy of antiinflammatory agents: retrospective and confirmatory studies of sepsis. Am J Respir Crit Care Med. 2002;166:1197-1205.
    • (2002) Am J Respir Crit Care Med , vol.166 , pp. 1197-1205
    • Eichacker, P.Q.1    Parent, C.2    Kalil, A.3
  • 47
    • 0035046049 scopus 로고    scopus 로고
    • Randomized, placebo-controlled trial of the anti-tumor necrosis factor antibody fragment afelimomab in hyperinflammatory response during severe sepsis: The RAMSES Study
    • Reinhart K, Menges T, Gardlund B, et al. Randomized, placebo-controlled trial of the anti-tumor necrosis factor antibody fragment afelimomab in hyperinflammatory response during severe sepsis: The RAMSES Study. Crit Care Med.2001;29:765-769.
    • (2001) Crit Care Med , vol.29 , pp. 765-769
    • Reinhart, K.1    Menges, T.2    Gardlund, B.3
  • 48
    • 8544262221 scopus 로고    scopus 로고
    • Efficacy and safety of the monoclonal anti-tumor necrosis factor antibody F(ab’)2 fragment afelimomab in patients with severe sepsis and elevated interleukin-6 levels
    • Panacek EA, Marshall JC, Albertson TE, et al. Efficacy and safety of the monoclonal anti-tumor necrosis factor antibody F(ab’)2 fragment afelimomab in patients with severe sepsis and elevated interleukin-6 levels. Crit Care Med.2004;32:2173-2182.
    • (2004) Crit Care Med , vol.32 , pp. 2173-2182
    • Panacek, E.A.1    Marshall, J.C.2    Albertson, T.E.3
  • 49
    • 84992808664 scopus 로고    scopus 로고
    • New directions in research of severe sepsis: a careful analysis of the MONARCS trial
    • Available at:
    • Dellinger, RP, McCarthy, R. New directions in research of severe sepsis: a careful analysis of the MONARCS trial. Medscape, 2001. Available at: http://www.medscape.com.
    • (2001) Medscape
    • Dellinger, R.P.1    McCarthy, R.2
  • 50
    • 0036152550 scopus 로고    scopus 로고
    • Effect of the interleukin-6 promoter polymorphism (-174 G/C) on the incidence and outcome of sepsis
    • Schluter B, Raufhake C, Erren M, et al. Effect of the interleukin-6 promoter polymorphism (-174 G/C) on the incidence and outcome of sepsis. Crit Care Med. 2002;30:32-37.
    • (2002) Crit Care Med , vol.30 , pp. 32-37
    • Schluter, B.1    Raufhake, C.2    Erren, M.3
  • 51
    • 0036151361 scopus 로고    scopus 로고
    • Posttraumatic immune modulation in chronic alcoholics is associated with multiple organ dysfunction syndrome
    • von Heymann C, Langenkamp J, Dubisz N, et al. Posttraumatic immune modulation in chronic alcoholics is associated with multiple organ dysfunction syndrome. J Trauma. 2002;52:95-103.
    • (2002) J Trauma , vol.52 , pp. 95-103
    • von Heymann, C.1    Langenkamp, J.2    Dubisz, N.3
  • 53
    • 0037350758 scopus 로고    scopus 로고
    • Correlation between transcranial interleukin-6 gradient and outcome in patients with acute brain injury
    • Minambres E, Cemborain A, Sanchez-Velasco P, et al. Correlation between transcranial interleukin-6 gradient and outcome in patients with acute brain injury. Crit Care Med.2003;31:933-938.
    • (2003) Crit Care Med , vol.31 , pp. 933-938
    • Minambres, E.1    Cemborain, A.2    Sanchez-Velasco, P.3
  • 54
    • 0346993065 scopus 로고    scopus 로고
    • Inflammation markers and risk factors for recurrence in 35 patients with a post-traumatic chronic subdural hematoma: a prospective study
    • Frati A, Salvati M, Mainiero F, et al. Inflammation markers and risk factors for recurrence in 35 patients with a post-traumatic chronic subdural hematoma: a prospective study. J Neurosurg. 2004;100:24-32.
    • (2004) J Neurosurg , vol.100 , pp. 24-32
    • Frati, A.1    Salvati, M.2    Mainiero, F.3
  • 55
    • 0034955738 scopus 로고    scopus 로고
    • Major secondary surgery in blunt trauma patients and perioperative cytokine liberation: determination of the clinical relevance of biochemical markers
    • Pape HC, van Griensven M, Rice J, Major secondary surgery in blunt trauma patients and perioperative cytokine liberation: determination of the clinical relevance of biochemical markers. J Trauma. 2001;50:989-1000.
    • (2001) J Trauma , vol.50 , pp. 989-1000
    • Pape, H.C.1    van Griensven, M.2    Rice, J.3
  • 56
    • 0038785690 scopus 로고    scopus 로고
    • Impact of intramedullary instrumentation versus damage control for femoral fractures on immunoinflammatory parameters: prospective randomized analysis by the EPOFF Study Group
    • Pape HC, Grimme K, Van Griensven M, Impact of intramedullary instrumentation versus damage control for femoral fractures on immunoinflammatory parameters: prospective randomized analysis by the EPOFF Study Group. J Trauma. 2003;55:7-13.
    • (2003) J Trauma , vol.55 , pp. 7-13
    • Pape, H.C.1    Grimme, K.2    Van Griensven, M.3
  • 57
    • 0035164538 scopus 로고    scopus 로고
    • Safety and dose relationship of recombinant human activated protein C for coagulopathy in severe sepsis
    • Bernard GR, Ely EW, Wright TJ, Safety and dose relationship of recombinant human activated protein C for coagulopathy in severe sepsis. Crit Care Med 2001;29:2051-2059.
    • (2001) Crit Care Med , vol.29 , pp. 2051-2059
    • Bernard, G.R.1    Ely, E.W.2    Wright, T.J.3
  • 58
    • 0035826096 scopus 로고    scopus 로고
    • Recombinant human protein C Worldwide Evaluation in Severe Sepsis (PROWESS) study group. Efficacy and safety of recombinant human activated protein C for severe sepsis
    • Bernard GR, Vincent JL, Laterre PF, Recombinant human protein C Worldwide Evaluation in Severe Sepsis (PROWESS) study group. Efficacy and safety of recombinant human activated protein C for severe sepsis. N Engl J Med 2001;344:699-709.
    • (2001) N Engl J Med , vol.344 , pp. 699-709
    • Bernard, G.R.1    Vincent, J.L.2    Laterre, P.F.3
  • 59
    • 10744233555 scopus 로고    scopus 로고
    • Plasma atrial natriuretic peptide and brain natriuretic peptide are increased in septic shock: impact of interleukin-6 and sepsis-associated left ventricular dysfunction
    • Witthaut R, Busch C, Fraunberger P, Plasma atrial natriuretic peptide and brain natriuretic peptide are increased in septic shock: impact of interleukin-6 and sepsis-associated left ventricular dysfunction. Intensive Care Med. 2003;29:1696-1702.
    • (2003) Intensive Care Med , vol.29 , pp. 1696-1702
    • Witthaut, R.1    Busch, C.2    Fraunberger, P.3
  • 60
    • 0037353346 scopus 로고    scopus 로고
    • Anti-inflammatory cytokine response and the development of multiple organ failure in severe sepsis
    • Loisa P, Rinne T, Laine S, Anti-inflammatory cytokine response and the development of multiple organ failure in severe sepsis. Acta Anaesthesiol Scand. 2003;47:319-325.
    • (2003) Acta Anaesthesiol Scand , vol.47 , pp. 319-325
    • Loisa, P.1    Rinne, T.2    Laine, S.3
  • 61
    • 0036040010 scopus 로고    scopus 로고
    • Predictive value of procalcitonin and interleukin 6 in critically ill patients with suspected sepsis
    • Pettila V, Hynninen M, Takkunen O, Kuusela P, Valtonen M. Predictive value of procalcitonin and interleukin 6 in critically ill patients with suspected sepsis. Intensive Care Med. 2002; 28: 1220-1225.
    • (2002) Intensive Care Med , vol.28 , pp. 1220-1225
    • Pettila, V.1    Hynninen, M.2    Takkunen, O.3    Kuusela, P.4    Valtonen, M.5
  • 62
    • 0035116930 scopus 로고    scopus 로고
    • Filgrastim in patients with pneumonia and severe sepsis or septic shock
    • Wunderink R, Leeper K Jr, Schein R, Filgrastim in patients with pneumonia and severe sepsis or septic shock. Chest. 2001;119:523-529.
    • (2001) Chest , vol.119 , pp. 523-529
    • Wunderink, R.1    Leeper, K.2    Schein, R.3
  • 63
    • 9144265427 scopus 로고    scopus 로고
    • Role of interleukin 6 in myocardial dysfunction of meningococcal septic shock
    • Pathan N, Hemingway CA, Alizadeh AA, Role of interleukin 6 in myocardial dysfunction of meningococcal septic shock. Lancet. 2004;363:203-209.
    • (2004) Lancet , vol.363 , pp. 203-209
    • Pathan, N.1    Hemingway, C.A.2    Alizadeh, A.A.3
  • 64
    • 0035292648 scopus 로고    scopus 로고
    • Chemokines and interleukin-18 are up-regulated in bronchoalveolar lavage fluid but not in serum of septic surgical ICU patients
    • Mathiak G, Neville LF, Grass G, Chemokines and interleukin-18 are up-regulated in bronchoalveolar lavage fluid but not in serum of septic surgical ICU patients. Shock. 2001;15:176-180.
    • (2001) Shock , vol.15 , pp. 176-180
    • Mathiak, G.1    Neville, L.F.2    Grass, G.3
  • 65
    • 0036124431 scopus 로고    scopus 로고
    • ARDS: the future
    • Wong, H. ARDS: the future. Crit Care Clin. 2002;18: 177-196.
    • (2002) Crit Care Clin , vol.18 , pp. 177-196
    • Wong, H.1
  • 66
    • 0039484556 scopus 로고    scopus 로고
    • Chemokine activation within 24 hours after blunt accident trauma
    • Liener UC, Bruckner UB, Knoferl MW, Chemokine activation within 24 hours after blunt accident trauma. Shock. 2002;17:169-172.
    • (2002) Shock , vol.17 , pp. 169-172
    • Liener, U.C.1    Bruckner, U.B.2    Knoferl, M.W.3
  • 67
    • 0036594378 scopus 로고    scopus 로고
    • Increased IL-10 Production and HLA-DR suppression in the lungs of injured patients precede the development of nosocomial pneumonia
    • Muehlstedt S, Lyte M, Rodriguez J. Increased IL-10 Production and HLA-DR suppression in the lungs of injured patients precede the development of nosocomial pneumonia. Shock. 2002;17:443-450.
    • (2002) Shock , vol.17 , pp. 443-450
    • Muehlstedt, S.1    Lyte, M.2    Rodriguez, J.3
  • 68
    • 12144273321 scopus 로고    scopus 로고
    • Association of interleukin-10 promoter polymorphism with the incidence of multiple organ dysfunction following major trauma: results of a prospective pilot study
    • Schroder O, Laun R, Held B, Ekkernkamp A, Schulte KM. Association of interleukin-10 promoter polymorphism with the incidence of multiple organ dysfunction following major trauma: results of a prospective pilot study. Shock.2004;21:306-310.
    • (2004) Shock , vol.21 , pp. 306-310
    • Schroder, O.1    Laun, R.2    Held, B.3    Ekkernkamp, A.4    Schulte, K.M.5
  • 69
    • 0042329263 scopus 로고    scopus 로고
    • Genotype and interleukin-10 responses after cardiopulmonary bypass
    • Galley HF, Lowe PR, Carmichael RL, Webster NR. Genotype and interleukin-10 responses after cardiopulmonary bypass. Br J Anaesth. 2003;91:424-426.
    • (2003) Br J Anaesth , vol.91 , pp. 424-426
    • Galley, H.F.1    Lowe, P.R.2    Carmichael, R.L.3    Webster, N.R.4
  • 70
    • 0034973298 scopus 로고    scopus 로고
    • Long-term-impaired expression of nuclear factor-kappa B and I kappa B alpha in peripheral blood mononuclear cells of trauma patients
    • Adib-Conquy M, Asehnoune K, Moine P, Cavaillon JM. Long-term-impaired expression of nuclear factor-kappa B and I kappa B alpha in peripheral blood mononuclear cells of trauma patients. J Leukoc Biol. 2001;70:30-38.
    • (2001) J Leukoc Biol , vol.70 , pp. 30-38
    • Adib-Conquy, M.1    Asehnoune, K.2    Moine, P.3    Cavaillon, J.M.4
  • 71
    • 0041384470 scopus 로고    scopus 로고
    • Predictive value of monocyte histocompatibility leukocyte antigen-DR expression and plasma interleukin-4 and -10 levels in critically ill patients with sepsis
    • Hynninen M, Pettila V, Takkunen O, Predictive value of monocyte histocompatibility leukocyte antigen-DR expression and plasma interleukin-4 and -10 levels in critically ill patients with sepsis. Shock. 2003;20:1-4.
    • (2003) Shock , vol.20 , pp. 1-4
    • Hynninen, M.1    Pettila, V.2    Takkunen, O.3
  • 72
    • 0036796873 scopus 로고    scopus 로고
    • Anti-interleukin-8 autoantibodies in patients at risk for acute respiratory distress syndrome
    • Kurdowska A, Noble JM, Grant IS, Anti-interleukin-8 autoantibodies in patients at risk for acute respiratory distress syndrome. Crit Care Med. 2002;30:2335-2337.
    • (2002) Crit Care Med , vol.30 , pp. 2335-2337
    • Kurdowska, A.1    Noble, J.M.2    Grant, I.S.3
  • 73
    • 0346786215 scopus 로고    scopus 로고
    • Association of endogenous G-CSF with anti-inflammatory mediators in patients with acute respiratory distress syndrome
    • Wiedermann FJ, Mayr AJ, Hobisch-Hagen P, Fuchs D, Schobersberger W. Association of endogenous G-CSF with anti-inflammatory mediators in patients with acute respiratory distress syndrome. J Interferon Cytokine Res. 2003;23:729-736.
    • (2003) J Interferon Cytokine Res , vol.23 , pp. 729-736
    • Wiedermann, F.J.1    Mayr, A.J.2    Hobisch-Hagen, P.3    Fuchs, D.4    Schobersberger, W.5
  • 74
    • 1642534563 scopus 로고    scopus 로고
    • Alveolar granulocyte colony-stimulating factor and alpha-chemokines in relation to serum levels, pulmonary neutrophilia, and severity of lung injury in ARDS
    • Wiedermann FJ, Mayr AJ, Kaneider NC, Alveolar granulocyte colony-stimulating factor and alpha-chemokines in relation to serum levels, pulmonary neutrophilia, and severity of lung injury in ARDS. Chest. 2004;125:212-219.
    • (2004) Chest , vol.125 , pp. 212-219
    • Wiedermann, F.J.1    Mayr, A.J.2    Kaneider, N.C.3
  • 75
    • 0036020303 scopus 로고    scopus 로고
    • Kinetic and reversibility of mechanical ventilation-associated pulmonary and systemic inflammatory response in patients with acute lung injury
    • Stuber F, Wrigge H, Schroeder S, Kinetic and reversibility of mechanical ventilation-associated pulmonary and systemic inflammatory response in patients with acute lung injury. Intensive Care Med. 2002;28:834-841.
    • (2002) Intensive Care Med , vol.28 , pp. 834-841
    • Stuber, F.1    Wrigge, H.2    Schroeder, S.3
  • 76
    • 0037352374 scopus 로고    scopus 로고
    • Bronchoalveolar interleukin-1 beta: a marker of bacterial burden in mechanically ventilated patients with community-acquired pneumonia
    • Wu CL, Lee YL, Chang KM, Bronchoalveolar interleukin-1 beta: a marker of bacterial burden in mechanically ventilated patients with community-acquired pneumonia. Crit Care Med. 2003;31:812-827.
    • (2003) Crit Care Med , vol.31 , pp. 812-827
    • Wu, C.L.1    Lee, Y.L.2    Chang, K.M.3
  • 77
    • 0037223847 scopus 로고    scopus 로고
    • Elevated serum levels of the type I and type II receptors for tumor necrosis factor-alpha as predictive factors for ARF in patients with septic shock
    • Iglesias J, Marik PE, Levine JS, Norasept II Study Investigators. Elevated serum levels of the type I and type II receptors for tumor necrosis factor-alpha as predictive factors for ARF in patients with septic shock. Am J Kidney Dis. 2003;41:62-75.
    • (2003) Am J Kidney Dis , vol.41 , pp. 62-75
    • Iglesias, J.1    Marik, P.E.2    Levine, J.S.3
  • 78
    • 12144289562 scopus 로고    scopus 로고
    • Plasma cytokine levels predict mortality in patients with acute renal failure
    • Simmons EM, Himmelfarb J, Sezer MT, Plasma cytokine levels predict mortality in patients with acute renal failure. Kidney Int. 2004;65:1357-1365.
    • (2004) Kidney Int , vol.65 , pp. 1357-1365
    • Simmons, E.M.1    Himmelfarb, J.2    Sezer, M.T.3
  • 79
    • 0036154952 scopus 로고    scopus 로고
    • A phase II randomized, controlled trial of continuous hemofiltration in sepsis
    • Cole L, Bellomo R, Hart G, A phase II randomized, controlled trial of continuous hemofiltration in sepsis. Crit Care Med. 2002;30:100-106.
    • (2002) Crit Care Med , vol.30 , pp. 100-106
    • Cole, L.1    Bellomo, R.2    Hart, G.3
  • 80
    • 8544275811 scopus 로고    scopus 로고
    • Interleukin-18: recent advances
    • Reddy, P. Interleukin-18: recent advances. Curr Opin Hematol. 2004;11:405-410.
    • (2004) Curr Opin Hematol , vol.11 , pp. 405-410
    • Reddy, P.1
  • 81
    • 0037374036 scopus 로고    scopus 로고
    • Matrix metalloproteinase-1 and cytokines in patients with acute pancreatitis
    • Nakae H, Endo S, Inoue Y, Matrix metalloproteinase-1 and cytokines in patients with acute pancreatitis. Pancreas.2003;26:134-138.
    • (2003) Pancreas , vol.26 , pp. 134-138
    • Nakae, H.1    Endo, S.2    Inoue, Y.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.