메뉴 건너뛰기




Volumn 33, Issue 7, 2012, Pages 1329-1342

Intracellular Aβ-oligomers and early inflammation in a model of Alzheimer's disease

Author keywords

A oligomers; COX 2; Inflammation; INOS; Preclinical Alzheimer's disease

Indexed keywords

AMYLOID BETA PROTEIN; CD40 ANTIGEN; CYCLOOXYGENASE 2; INDUCIBLE NITRIC OXIDE SYNTHASE; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2;

EID: 84861183285     PISSN: 01974580     EISSN: 15581497     Source Type: Journal    
DOI: 10.1016/j.neurobiolaging.2011.01.007     Document Type: Article
Times cited : (129)

References (74)
  • 1
    • 20244364226 scopus 로고    scopus 로고
    • Up-regulation of the inflammatory cytokines IFN-gamma and IL-12 and down-regulation of IL-4 in cerebral cortex regions of APP(SWE) transgenic mice
    • Abbas N., Bednar I., Mix E., Marie S., Paterson D., Ljungberg A., Morris C., Winblad B., Nordberg A., Zhu J. Up-regulation of the inflammatory cytokines IFN-gamma and IL-12 and down-regulation of IL-4 in cerebral cortex regions of APP(SWE) transgenic mice. J. Neuroimmunol 2002, 126:50-57.
    • (2002) J. Neuroimmunol , vol.126 , pp. 50-57
    • Abbas, N.1    Bednar, I.2    Mix, E.3    Marie, S.4    Paterson, D.5    Ljungberg, A.6    Morris, C.7    Winblad, B.8    Nordberg, A.9    Zhu, J.10
  • 2
    • 34250796207 scopus 로고    scopus 로고
    • Actin-binding proteins coronin-1a and IBA-1 are effective microglial markers for immunohistochemistry
    • Ahmed Z., Shaw G., Sharma V.P., Yang C., McGowan E., Dickson D.W. Actin-binding proteins coronin-1a and IBA-1 are effective microglial markers for immunohistochemistry. J. Histochem. Cytochem 2007, 55:687-700.
    • (2007) J. Histochem. Cytochem , vol.55 , pp. 687-700
    • Ahmed, Z.1    Shaw, G.2    Sharma, V.P.3    Yang, C.4    McGowan, E.5    Dickson, D.W.6
  • 5
    • 0029021217 scopus 로고
    • Do nonsteroidal anti-inflammatory drugs decrease the risk for Alzheimer's disease?. The Rotterdam Study
    • Andersen K., Launer L.J., Ott A., Hoes A.W., Breteler M.M., Hofman A. Do nonsteroidal anti-inflammatory drugs decrease the risk for Alzheimer's disease?. The Rotterdam Study. Neurology 1995, 45:1441-1445.
    • (1995) Neurology , vol.45 , pp. 1441-1445
    • Andersen, K.1    Launer, L.J.2    Ott, A.3    Hoes, A.W.4    Breteler, M.M.5    Hofman, A.6
  • 6
    • 68049129231 scopus 로고    scopus 로고
    • Treatment Effects of NSAIDs Related to Stage of Alzheimer's Disease Pathogenesis-Lessons from ADAPT
    • Breitner J.C. Treatment Effects of NSAIDs Related to Stage of Alzheimer's Disease Pathogenesis-Lessons from ADAPT. 9th International Conference of Alzheimer's Disease 2009.
    • (2009) 9th International Conference of Alzheimer's Disease
    • Breitner, J.C.1
  • 7
    • 0041784698 scopus 로고    scopus 로고
    • Inflammatory neurodegeneration mediated by nitric oxide, glutamate, and mitochondria
    • Brown G.C., Bal-Price A. Inflammatory neurodegeneration mediated by nitric oxide, glutamate, and mitochondria. Mol. Neurobiol 2003, 27:325-355.
    • (2003) Mol. Neurobiol , vol.27 , pp. 325-355
    • Brown, G.C.1    Bal-Price, A.2
  • 9
    • 73349089956 scopus 로고    scopus 로고
    • Increased matrix metalloproteinase 9 activity in mild cognitive impairment
    • Bruno M.A., Mufson E.J., Wuu J., Cuello A.C. Increased matrix metalloproteinase 9 activity in mild cognitive impairment. J. Neuropathol. Exp. Neurol 2009, 68:1309-1318.
    • (2009) J. Neuropathol. Exp. Neurol , vol.68 , pp. 1309-1318
    • Bruno, M.A.1    Mufson, E.J.2    Wuu, J.3    Cuello, A.C.4
  • 11
    • 79951709033 scopus 로고    scopus 로고
    • Overview of the Alzheimer's Disease Pathology and Potential Therapeutic Targets
    • Springer, New York, A.C. Cuello (Ed.)
    • Cuello A.C. Overview of the Alzheimer's Disease Pathology and Potential Therapeutic Targets. Pharmacological Mechanisms in Alzheimer's Therapeutics 2007, Springer, New York. A.C. Cuello (Ed.).
    • (2007) Pharmacological Mechanisms in Alzheimer's Therapeutics
    • Cuello, A.C.1
  • 12
    • 0033559375 scopus 로고    scopus 로고
    • Phagocytosis stimulates alternative glycosylation of macrosialin (mouse CD68), a macrophage-specific endosomal protein
    • da Silva R.P., Gordon S. Phagocytosis stimulates alternative glycosylation of macrosialin (mouse CD68), a macrophage-specific endosomal protein. Biochem. J 1999, 338:687-694.
    • (1999) Biochem. J , vol.338 , pp. 687-694
    • da Silva, R.P.1    Gordon, S.2
  • 13
    • 37249094173 scopus 로고    scopus 로고
    • From inflammation to sickness and depression: when the immune system subjugates the brain
    • Dantzer R., O'Connor J.C., Freund G.G., Johnson R.W., Kelley K.W. From inflammation to sickness and depression: when the immune system subjugates the brain. Nat. Rev. Neurosci 2008, 9:46-56.
    • (2008) Nat. Rev. Neurosci , vol.9 , pp. 46-56
    • Dantzer, R.1    O'Connor, J.C.2    Freund, G.G.3    Johnson, R.W.4    Kelley, K.W.5
  • 16
    • 33646841989 scopus 로고    scopus 로고
    • Beta-amyloid stimulates murine postnatal and adult microglia cultures in a unique manner
    • Floden A.M., Combs C.K. Beta-amyloid stimulates murine postnatal and adult microglia cultures in a unique manner. J. Neurosci 2006, 26:4644-4648.
    • (2006) J. Neurosci , vol.26 , pp. 4644-4648
    • Floden, A.M.1    Combs, C.K.2
  • 18
    • 0029902166 scopus 로고    scopus 로고
    • Evidence of neuronal oxidative damage in Alzheimer's disease
    • Good P.F., Werner P., Hsu A., Olanow C.W., Perl D.P. Evidence of neuronal oxidative damage in Alzheimer's disease. Am. J. Pathol 1996, 149:21-28.
    • (1996) Am. J. Pathol , vol.149 , pp. 21-28
    • Good, P.F.1    Werner, P.2    Hsu, A.3    Olanow, C.W.4    Perl, D.P.5
  • 19
    • 0034490025 scopus 로고    scopus 로고
    • Abeta immunoreactive material is present in several intracellular compartments in transfected, neuronally differentiated, P19 cells expressing the human amyloid beta-protein precursor
    • Grant S.M., Ducatenzeiler A., Szyf M., Cuello A.C. Abeta immunoreactive material is present in several intracellular compartments in transfected, neuronally differentiated, P19 cells expressing the human amyloid beta-protein precursor. J Alzheimers Dis 2000, 2:207-222.
    • (2000) J Alzheimers Dis , vol.2 , pp. 207-222
    • Grant, S.M.1    Ducatenzeiler, A.2    Szyf, M.3    Cuello, A.C.4
  • 20
    • 35548986304 scopus 로고    scopus 로고
    • Microglia: active sensor and versatile effector cells in the normal and pathologic brain
    • Hanisch U.K., Kettenmann H. Microglia: active sensor and versatile effector cells in the normal and pathologic brain. Nat. Neurosci 2007, 10:1387-1394.
    • (2007) Nat. Neurosci , vol.10 , pp. 1387-1394
    • Hanisch, U.K.1    Kettenmann, H.2
  • 22
    • 34247508686 scopus 로고    scopus 로고
    • Cell cycle regulation in the postmitotic neuron: oxymoron or new biology?
    • Herrup K., Yang Y. Cell cycle regulation in the postmitotic neuron: oxymoron or new biology?. Nat. Rev. Neurosci 2007, 8:368-378.
    • (2007) Nat. Rev. Neurosci , vol.8 , pp. 368-378
    • Herrup, K.1    Yang, Y.2
  • 23
    • 0033597564 scopus 로고    scopus 로고
    • Long-term intracerebral inflammatory response after experimental focal brain injury in rat
    • Holmin S., Mathiesen T. Long-term intracerebral inflammatory response after experimental focal brain injury in rat. Neuroreport 1999, 10:1889-1891.
    • (1999) Neuroreport , vol.10 , pp. 1889-1891
    • Holmin, S.1    Mathiesen, T.2
  • 24
    • 77957020887 scopus 로고    scopus 로고
    • Are we prepared to deal with the Alzheimer's disease pandemic?
    • Holtzman J.L. Are we prepared to deal with the Alzheimer's disease pandemic?. Clin. Pharmacol. Ther 2010, 88:563-565.
    • (2010) Clin. Pharmacol. Ther , vol.88 , pp. 563-565
    • Holtzman, J.L.1
  • 25
    • 0036323485 scopus 로고    scopus 로고
    • Cyclin D1 and cyclin E are co-localized with cyclo-oxygenase 2 (COX-2) in pyramidal neurons in Alzheimer disease temporal cortex
    • Hoozemans J.J., Bruckner M.K., Rozemuller A.J., Veerhuis R., Eikelenboom P., Arendt T. Cyclin D1 and cyclin E are co-localized with cyclo-oxygenase 2 (COX-2) in pyramidal neurons in Alzheimer disease temporal cortex. J. Neuropathol. Exp. Neurol 2002, 61:678-688.
    • (2002) J. Neuropathol. Exp. Neurol , vol.61 , pp. 678-688
    • Hoozemans, J.J.1    Bruckner, M.K.2    Rozemuller, A.J.3    Veerhuis, R.4    Eikelenboom, P.5    Arendt, T.6
  • 26
    • 0141644282 scopus 로고    scopus 로고
    • The impact of Abeta-plaques on cortical cholinergic and non-cholinergic presynaptic boutons in alzheimer's disease-like transgenic mice
    • Hu L., Wong T.P., Cote S.L., Bell K.F., Cuello A.C. The impact of Abeta-plaques on cortical cholinergic and non-cholinergic presynaptic boutons in alzheimer's disease-like transgenic mice. Neuroscience 2003, 121:421-432.
    • (2003) Neuroscience , vol.121 , pp. 421-432
    • Hu, L.1    Wong, T.P.2    Cote, S.L.3    Bell, K.F.4    Cuello, A.C.5
  • 27
    • 0033043532 scopus 로고    scopus 로고
    • Cyclooxygenase-2 immunoreactivity in the human brain following cerebral ischemia
    • Iadecola C., Forster C., Nogawa S., Clark H.B., Ross M.E. Cyclooxygenase-2 immunoreactivity in the human brain following cerebral ischemia. Acta Neuropathol 1999, 98:9-14.
    • (1999) Acta Neuropathol , vol.98 , pp. 9-14
    • Iadecola, C.1    Forster, C.2    Nogawa, S.3    Clark, H.B.4    Ross, M.E.5
  • 28
    • 27744482552 scopus 로고    scopus 로고
    • Early correlation of microglial activation with enhanced tumor necrosis factor-alpha and monocyte chemoattractant protein-1 expression specifically within the entorhinal cortex of triple transgenic Alzheimer's disease mice
    • Janelsins M.C., Mastrangelo M.A., Oddo S., LaFerla F.M., Federoff H.J., Bowers W.J. Early correlation of microglial activation with enhanced tumor necrosis factor-alpha and monocyte chemoattractant protein-1 expression specifically within the entorhinal cortex of triple transgenic Alzheimer's disease mice. J. Neuroinflammation 2005, 2:23.
    • (2005) J. Neuroinflammation , vol.2 , pp. 23
    • Janelsins, M.C.1    Mastrangelo, M.A.2    Oddo, S.3    LaFerla, F.M.4    Federoff, H.J.5    Bowers, W.J.6
  • 29
    • 22144489808 scopus 로고    scopus 로고
    • Non-steroidal anti-inflammatory drugs (NSAIDs) and other anti-inflammatory agents in the treatment of neurodegenerative disease
    • Klegeris A., McGeer P.L. Non-steroidal anti-inflammatory drugs (NSAIDs) and other anti-inflammatory agents in the treatment of neurodegenerative disease. Curr. Alzheimer Res 2005, 2:355-365.
    • (2005) Curr. Alzheimer Res , vol.2 , pp. 355-365
    • Klegeris, A.1    McGeer, P.L.2
  • 32
    • 77956955758 scopus 로고    scopus 로고
    • The role of microglia in amyloid clearance from the AD brain
    • Lee C.Y., Landreth G.E. The role of microglia in amyloid clearance from the AD brain. J. Neural Transm 2010, 117:949-960.
    • (2010) J. Neural Transm , vol.117 , pp. 949-960
    • Lee, C.Y.1    Landreth, G.E.2
  • 33
    • 0035860603 scopus 로고    scopus 로고
    • Expression of endothelial and inducible NOS-isoforms is increased in Alzheimer's disease in APP23 transgenic mice and after experimental brain lesion in rat: evidence for an induction by amyloid pathology
    • Luth H.J., Holzer M., Gartner U., Staufenbiel M., Arendt T. Expression of endothelial and inducible NOS-isoforms is increased in Alzheimer's disease in APP23 transgenic mice and after experimental brain lesion in rat: evidence for an induction by amyloid pathology. Brain Res 2001, 913:57-67.
    • (2001) Brain Res , vol.913 , pp. 57-67
    • Luth, H.J.1    Holzer, M.2    Gartner, U.3    Staufenbiel, M.4    Arendt, T.5
  • 35
    • 36949009636 scopus 로고    scopus 로고
    • Cognitive impairment and transmitter-specific pre- and postsynaptic changes in the rat cerebral cortex during ageing
    • Majdi M., Ribeiro-da-Silva A., Cuello A.C. Cognitive impairment and transmitter-specific pre- and postsynaptic changes in the rat cerebral cortex during ageing. Eur. J. Neurosci 2007, 26:3583-3596.
    • (2007) Eur. J. Neurosci , vol.26 , pp. 3583-3596
    • Majdi, M.1    Ribeiro-da-Silva, A.2    Cuello, A.C.3
  • 36
    • 11844255779 scopus 로고    scopus 로고
    • Bone-marrow-derived cells contribute to the recruitment of microglial cells in response to beta-amyloid deposition in APP/PS1 double transgenic Alzheimer mice
    • Malm T.M., Koistinaho M., Parepalo M., Vatanen T., Ooka A., Karlsson S., Koistinaho J. Bone-marrow-derived cells contribute to the recruitment of microglial cells in response to beta-amyloid deposition in APP/PS1 double transgenic Alzheimer mice. Neurobiol. Dis 2005, 18:134-142.
    • (2005) Neurobiol. Dis , vol.18 , pp. 134-142
    • Malm, T.M.1    Koistinaho, M.2    Parepalo, M.3    Vatanen, T.4    Ooka, A.5    Karlsson, S.6    Koistinaho, J.7
  • 37
    • 26644452073 scopus 로고    scopus 로고
    • Macrophage polarization comes of age
    • Mantovani A., Sica A., Locati M. Macrophage polarization comes of age. Immunity 2005, 23:344-346.
    • (2005) Immunity , vol.23 , pp. 344-346
    • Mantovani, A.1    Sica, A.2    Locati, M.3
  • 38
    • 47549107705 scopus 로고    scopus 로고
    • Cognitive function over time in the Alzheimer's Disease Anti-inflammatory Prevention Trial (ADAPT): results of a randomized, controlled trial of naproxen and celecoxib
    • Martin B.K., Szekely C., Brandt J., Piantadosi S., Breitner J.C., Craft S., Evans D., Green R., Mullan M. Cognitive function over time in the Alzheimer's Disease Anti-inflammatory Prevention Trial (ADAPT): results of a randomized, controlled trial of naproxen and celecoxib. Arch. Neurol 2008, 65:896-905.
    • (2008) Arch. Neurol , vol.65 , pp. 896-905
    • Martin, B.K.1    Szekely, C.2    Brandt, J.3    Piantadosi, S.4    Breitner, J.C.5    Craft, S.6    Evans, D.7    Green, R.8    Mullan, M.9
  • 40
    • 0025332027 scopus 로고
    • Anti-inflammatory drugs and Alzheimer disease
    • McGeer P.L., McGeer E., Rogers J., Sibley J. Anti-inflammatory drugs and Alzheimer disease. Lancet 1990, 335:1037.
    • (1990) Lancet , vol.335 , pp. 1037
    • McGeer, P.L.1    McGeer, E.2    Rogers, J.3    Sibley, J.4
  • 41
    • 84880185810 scopus 로고    scopus 로고
    • Inflammation, anti-inflammatory agents and Alzheimer disease: the last 12 years
    • McGeer P.L., Rogers J., McGeer E.G. Inflammation, anti-inflammatory agents and Alzheimer disease: the last 12 years. J. Alzheimers Dis 2006, 9:271-276.
    • (2006) J. Alzheimers Dis , vol.9 , pp. 271-276
    • McGeer, P.L.1    Rogers, J.2    McGeer, E.G.3
  • 42
    • 62849112328 scopus 로고    scopus 로고
    • Alzheimer's Disease Anti-inflammatory Prevention Trial: design, methods, and baseline results
    • Meinert C.L., McCaffrey L.D., Breitner J.C. Alzheimer's Disease Anti-inflammatory Prevention Trial: design, methods, and baseline results. Alzheimers Dement 2009, 5:93-104.
    • (2009) Alzheimers Dement , vol.5 , pp. 93-104
    • Meinert, C.L.1    McCaffrey, L.D.2    Breitner, J.C.3
  • 43
    • 4444333049 scopus 로고    scopus 로고
    • Cyclooxygenase-2 (COX-2) in inflammatory and degenerative brain diseases
    • Minghetti L. Cyclooxygenase-2 (COX-2) in inflammatory and degenerative brain diseases. J. Neuropathol. Exp. Neurol 2004, 63:901-910.
    • (2004) J. Neuropathol. Exp. Neurol , vol.63 , pp. 901-910
    • Minghetti, L.1
  • 44
    • 65649098369 scopus 로고    scopus 로고
    • The role of microglia in antibody-mediated clearance of amyloid-beta from the brain
    • Morgan D. The role of microglia in antibody-mediated clearance of amyloid-beta from the brain. CNS Neurol. Disord. Drug Targets 2009, 8:7-15.
    • (2009) CNS Neurol. Disord. Drug Targets , vol.8 , pp. 7-15
    • Morgan, D.1
  • 45
    • 0035168927 scopus 로고    scopus 로고
    • Pathologic correlates of nondemented aging, mild cognitive impairment, and early-stage Alzheimer's disease
    • Morris J.C., Price A.L. Pathologic correlates of nondemented aging, mild cognitive impairment, and early-stage Alzheimer's disease. J. Mol. Neurosci 2001, 17:101-118.
    • (2001) J. Mol. Neurosci , vol.17 , pp. 101-118
    • Morris, J.C.1    Price, A.L.2
  • 47
    • 0034492957 scopus 로고    scopus 로고
    • Expression of macrophage colony-stimulating factor receptor is increased in the AbetaPP(V717F) transgenic mouse model of Alzheimer's disease
    • Murphy G.M., Zhao F., Yang L., Cordell B. Expression of macrophage colony-stimulating factor receptor is increased in the AbetaPP(V717F) transgenic mouse model of Alzheimer's disease. Am. J. Pathol 2000, 157:895-904.
    • (2000) Am. J. Pathol , vol.157 , pp. 895-904
    • Murphy, G.M.1    Zhao, F.2    Yang, L.3    Cordell, B.4
  • 48
    • 19744380563 scopus 로고    scopus 로고
    • Resting microglial cells are highly dynamic surveillants of brain parenchyma in vivo
    • Nimmerjahn A., Kirchhoff F., Helmchen F. Resting microglial cells are highly dynamic surveillants of brain parenchyma in vivo. Science 2005, 308:1314-1318.
    • (2005) Science , vol.308 , pp. 1314-1318
    • Nimmerjahn, A.1    Kirchhoff, F.2    Helmchen, F.3
  • 50
    • 33144487701 scopus 로고    scopus 로고
    • Temporal profile of amyloid-beta (Abeta) oligomerization in an in vivo model of Alzheimer disease. A link between Abeta and tau pathology
    • Oddo S., Caccamo A., Tran L., Lambert M.P., Glabe C.G., Klein W.L., LaFerla F.M. Temporal profile of amyloid-beta (Abeta) oligomerization in an in vivo model of Alzheimer disease. A link between Abeta and tau pathology. J. Biol. Chem 2006, 281:1599-1604.
    • (2006) J. Biol. Chem , vol.281 , pp. 1599-1604
    • Oddo, S.1    Caccamo, A.2    Tran, L.3    Lambert, M.P.4    Glabe, C.G.5    Klein, W.L.6    LaFerla, F.M.7
  • 52
    • 0032551633 scopus 로고    scopus 로고
    • Cyclooxygenase-2 expression is increased in frontal cortex of Alzheimer's disease brain
    • Pasinetti G.M., Aisen P.S. Cyclooxygenase-2 expression is increased in frontal cortex of Alzheimer's disease brain. Neuroscience 1998, 87:319-324.
    • (1998) Neuroscience , vol.87 , pp. 319-324
    • Pasinetti, G.M.1    Aisen, P.S.2
  • 53
    • 69149095731 scopus 로고    scopus 로고
    • Early diagnosis of Alzheimer's disease: is MCI too late?
    • Petersen R.C. Early diagnosis of Alzheimer's disease: is MCI too late?. Curr. Alzheimer Res 2009, 6:324-330.
    • (2009) Curr. Alzheimer Res , vol.6 , pp. 324-330
    • Petersen, R.C.1
  • 55
    • 0035726544 scopus 로고    scopus 로고
    • Neuroinflammation-induced acceleration of amyloid deposition in the APPV717F transgenic mouse
    • Qiao X., Cummins D.J., Paul S.M. Neuroinflammation-induced acceleration of amyloid deposition in the APPV717F transgenic mouse. Eur. J. Neurosci 2001, 14:474-482.
    • (2001) Eur. J. Neurosci , vol.14 , pp. 474-482
    • Qiao, X.1    Cummins, D.J.2    Paul, S.M.3
  • 56
    • 0037376760 scopus 로고    scopus 로고
    • Inflammation and cerebral amyloidosis are disconnected in an animal model of Alzheimer's disease
    • Quinn J., Montine T., Morrow J., Woodward W.R., Kulhanek D., Eckenstein F. Inflammation and cerebral amyloidosis are disconnected in an animal model of Alzheimer's disease. J. Neuroimmunol 2003, 137:32-41.
    • (2003) J. Neuroimmunol , vol.137 , pp. 32-41
    • Quinn, J.1    Montine, T.2    Morrow, J.3    Woodward, W.R.4    Kulhanek, D.5    Eckenstein, F.6
  • 57
    • 0030298442 scopus 로고    scopus 로고
    • Deficient activation of microglia during optic nerve degeneration
    • Reichert F., Rotshenker S. Deficient activation of microglia during optic nerve degeneration. J. Neuroimmunol 1996, 70:153-161.
    • (1996) J. Neuroimmunol , vol.70 , pp. 153-161
    • Reichert, F.1    Rotshenker, S.2
  • 58
    • 74149092361 scopus 로고    scopus 로고
    • The role of Galectin-3/MAC-2 in the activation of the innate-immune function of phagocytosis in microglia in injury and disease
    • Rotshenker S. The role of Galectin-3/MAC-2 in the activation of the innate-immune function of phagocytosis in microglia in injury and disease. J. Mol. Neurosci 2009, 39:99-103.
    • (2009) J. Mol. Neurosci , vol.39 , pp. 99-103
    • Rotshenker, S.1
  • 61
    • 0035066332 scopus 로고    scopus 로고
    • Alzheimer's disease: genes, proteins, and therapy
    • Selkoe D.J. Alzheimer's disease: genes, proteins, and therapy. Physiol. Rev 2001, 81:741-766.
    • (2001) Physiol. Rev , vol.81 , pp. 741-766
    • Selkoe, D.J.1
  • 62
    • 0022365676 scopus 로고
    • Development of a mouse antiperoxidase secreting hybridoma for use in the production of a mouse PAP complex for immunocytochemistry and as a parent cell line in the development of hybrid hybridomas
    • Semenenko F.M., Bramwell S., Sidebottom E., Cuello A.C. Development of a mouse antiperoxidase secreting hybridoma for use in the production of a mouse PAP complex for immunocytochemistry and as a parent cell line in the development of hybrid hybridomas. Histochemistry 1985, 83:405-408.
    • (1985) Histochemistry , vol.83 , pp. 405-408
    • Semenenko, F.M.1    Bramwell, S.2    Sidebottom, E.3    Cuello, A.C.4
  • 63
    • 0042835437 scopus 로고    scopus 로고
    • Lipopolysaccharide-induced-neuroinflammation increases intracellular accumulation of amyloid precursor protein and amyloid beta peptide in APPswe transgenic mice
    • Sheng J.G., Bora S.H., Xu G., Borchelt D.R., Price D.L., Koliatsos V.E. Lipopolysaccharide-induced-neuroinflammation increases intracellular accumulation of amyloid precursor protein and amyloid beta peptide in APPswe transgenic mice. Neurobiol. Dis 2003, 14:133-145.
    • (2003) Neurobiol. Dis , vol.14 , pp. 133-145
    • Sheng, J.G.1    Bora, S.H.2    Xu, G.3    Borchelt, D.R.4    Price, D.L.5    Koliatsos, V.E.6
  • 64
    • 32344440522 scopus 로고    scopus 로고
    • Bone marrow-derived microglia play a critical role in restricting senile plaque formation in Alzheimer's disease
    • Simard A.R., Soulet D., Gowing G., Julien J.P., Rivest S. Bone marrow-derived microglia play a critical role in restricting senile plaque formation in Alzheimer's disease. Neuron 2006, 49:489-502.
    • (2006) Neuron , vol.49 , pp. 489-502
    • Simard, A.R.1    Soulet, D.2    Gowing, G.3    Julien, J.P.4    Rivest, S.5
  • 66
    • 0030897133 scopus 로고    scopus 로고
    • Risk of Alzheimer's disease and duration of NSAID use
    • Stewart W.F., Kawas C., Corrada M., Metter E.J. Risk of Alzheimer's disease and duration of NSAID use. Neurology 1997, 48:626-632.
    • (1997) Neurology , vol.48 , pp. 626-632
    • Stewart, W.F.1    Kawas, C.2    Corrada, M.3    Metter, E.J.4
  • 68
    • 0036209131 scopus 로고    scopus 로고
    • Post-training cyclooxygenase-2 (COX-2) inhibition impairs memory consolidation
    • Teather L.A., Packard M.G., Bazan N.G. Post-training cyclooxygenase-2 (COX-2) inhibition impairs memory consolidation. Learn. Mem 2002, 9:41-47.
    • (2002) Learn. Mem , vol.9 , pp. 41-47
    • Teather, L.A.1    Packard, M.G.2    Bazan, N.G.3
  • 71
    • 0027290813 scopus 로고
    • Expression of a mitogen-inducible cyclooxygenase in brain neurons: regulation by synaptic activity and glucocorticoids
    • Yamagata K., Andreasson K.I., Kaufmann W.E., Barnes C.A., Worley P.F. Expression of a mitogen-inducible cyclooxygenase in brain neurons: regulation by synaptic activity and glucocorticoids. Neuron 1993, 11:371-386.
    • (1993) Neuron , vol.11 , pp. 371-386
    • Yamagata, K.1    Andreasson, K.I.2    Kaufmann, W.E.3    Barnes, C.A.4    Worley, P.F.5
  • 72
    • 0033575336 scopus 로고    scopus 로고
    • Intracellular accumulation of insoluble, newly synthesized abetan-42 in amyloid precursor protein-transfected cells that have been treated with Abeta1-42
    • Yang A.J., Chandswangbhuvana D., Shu T., Henschen A., Glabe C.G. Intracellular accumulation of insoluble, newly synthesized abetan-42 in amyloid precursor protein-transfected cells that have been treated with Abeta1-42. J. Biol. Chem 1999, 274:20650-20656.
    • (1999) J. Biol. Chem , vol.274 , pp. 20650-20656
    • Yang, A.J.1    Chandswangbhuvana, D.2    Shu, T.3    Henschen, A.4    Glabe, C.G.5
  • 73
    • 1542315515 scopus 로고    scopus 로고
    • Temporal and topographic profiles of cyclooxygenase-2 expression during 24 h of focal brain ishemia in rats
    • Yokota C., Kaji T., Kuge Y., Inoue H., Tamaki N., Minematsu K. Temporal and topographic profiles of cyclooxygenase-2 expression during 24 h of focal brain ishemia in rats. Neurosci. Lett 2004, 357:219-222.
    • (2004) Neurosci. Lett , vol.357 , pp. 219-222
    • Yokota, C.1    Kaji, T.2    Kuge, Y.3    Inoue, H.4    Tamaki, N.5    Minematsu, K.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.