Interleukin-1 receptor antagonist reduced apoptosis and attenuated intestinal mucositis in a 5-fluorouracil chemotherapy model in mice

Cancer Chemotherapy and Pharmacology

Volumn 68, Issue 1, 2011, Pages 87-96

  Wu, Zhen Qian ^a   Han, Xiao Dong ^a   Wang, Yu ^a   Yuan, Ke Li ^a   Jin, Zhi Ming ^a   Di, Jian Zhong ^a   Yan, Jun ^a   Pan, Ye ^a   Zhang, Pin ^a   Huang, Xin Yu ^a   Wang, Zhi Gang ^a   Zheng, Qi ^a  

^a SHANGHAI JIAO TONG UNIVERSITY   (China)

Author keywords

Apoptosis; Chemotherapy; Interleukin 1 receptor antagonist; Mucositis

Indexed keywords

CASPASE 3; CYCLINE; FLUOROURACIL; HOE 33342; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; INTERLEUKIN 1BETA; PROTEIN BAX; PROTEIN BCL 2; PROTEIN BCL XL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CANCER CHEMOTHERAPY; CELL PROLIFERATION; CELL VIABILITY; CLINICAL PRACTICE; CONTROLLED STUDY; DIARRHEA; DISEASE SEVERITY; DOWN REGULATION; ENTEROPATHY; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; INTESTINE CELL; INTESTINE CRYPT; INTESTINE MUCOSITIS; MOUSE; MUCOSA INFLAMMATION; NICK END LABELING; NONHUMAN; ORGAN WEIGHT; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SMALL INTESTINE MUCOSA; TUMOR XENOGRAFT; UPREGULATION; WESTERN BLOTTING;

ANIMALS; ANTIMETABOLITES, ANTINEOPLASTIC; APOPTOSIS; BENZIMIDAZOLES; DIARRHEA; DISEASE MODELS, ANIMAL; FLUORESCENT DYES; FLUOROURACIL; HUMANS; INTERLEUKIN 1 RECEPTOR ANTAGONIST PROTEIN; INTESTINAL MUCOSA; INTESTINES; MALE; MICE; MICE, INBRED BALB C; MUCOSITIS;

EID: 79959624022     PISSN: 03445704     EISSN: 14320843     Source Type: Journal    
DOI: 10.1007/s00280-010-1451-5     Document Type: Article

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