5-Fluorouracil-induced intestinal toxicity: What determines the severity of damage to murine intestinal crypt epithelia?

Toxicology Letters

Volumn 133, Issue 2-3, 2002, Pages 231-240

  Inomata, Akira ^a   Horii, Ikuo ^a   Suzuki, Katsushi ^b  

^a NIPPON ROCHE RESEARCH CENTER   (Japan)

^b NIPPON VETERINARY AND LIFE SCIENCE UNIVERSITY   (Japan)

Author keywords

5 Fluorouracil; Apoptosis; Bax; Cell cycle arrest; Microautoradiography; p21WAF Cip1

Indexed keywords

FLUOROURACIL; PROTEIN BAX; PROTEIN P21;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; AUTORADIOGRAPHY; CELL CYCLE; CELL FATE; CELL NUCLEUS; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CORRELATION ANALYSIS; CYTOPLASM; DISEASE SEVERITY; EXPOSURE; HISTOLOGY; INFUSION; INTESTINE CRYPT; INTESTINE EPITHELIUM; INTESTINE INJURY; MALE; MITOSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DETERMINATION; PROTEIN EXPRESSION; TIME; TOXICITY;

ANIMALS; ANTIMETABOLITES; APOPTOSIS; AUTORADIOGRAPHY; BCL-2-ASSOCIATED X PROTEIN; BLOTTING, WESTERN; CELL CYCLE; CELL CYCLE PROTEINS; DUODENUM; EPITHELIAL CELLS; FLUOROURACIL; IMMUNOHISTOCHEMISTRY; INFUSIONS, INTRAVENOUS; INTESTINAL MUCOSA; MALE; MICE; ONCOGENE PROTEIN P21(RAS); PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2; RECTUM; TIME FACTORS;

MURINAE;

EID: 0037151247     PISSN: 03784274     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-4274(02)00204-7     Document Type: Article

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