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Volumn 12, Issue 2, 2012, Pages 159-167

Bone marrow microenvironment: A newly recognized target for diabetes-induced cellular damage

Author keywords

Bone marrow; Diabetes; Ischemia; Microenvironment; Osteoblastic niche; Stem cells; Vascular niche

Indexed keywords

ANGIOPOIETIN 1; C REACTIVE PROTEIN; CATHEPSIN G; CATHEPSIN K; CD34 ANTIGEN; ELASTASE; GELATINASE A; GELATINASE B; NERVE CELL ADHESION MOLECULE; NOTCH RECEPTOR; OSTEOCLAST DIFFERENTIATION FACTOR; OSTEOPONTIN; STEM CELL FACTOR; STROMAL CELL DERIVED FACTOR 1ALPHA; THROMBOPOIETIN; WNT PROTEIN;

EID: 84861166750     PISSN: 18715303     EISSN: 22123873     Source Type: Journal    
DOI: 10.2174/187153012800493530     Document Type: Review
Times cited : (10)

References (92)
  • 5
    • 78649324771 scopus 로고    scopus 로고
    • Long-term diabetes impairs repopulation of hematopoietic progenitor cells and dysregulates the cytokine expression in the bone marrow microenvironment in mice
    • Orlandi, A.; Chavakis, E.; Seeger, F.; Tjwa, M.; Zeiher, A. M. and Dimmeler, S. (2010) Long-term diabetes impairs repopulation of hematopoietic progenitor cells and dysregulates the cytokine expression in the bone marrow microenvironment in mice. Basic Res. Cardiol., 105, 703-712.
    • (2010) Basic Res. Cardiol. , vol.105 , pp. 703-712
    • Orlandi, A.1    Chavakis, E.2    Seeger, F.3    Tjwa, M.4    Zeiher, A.M.5    Dimmeler, S.6
  • 6
    • 79952271507 scopus 로고    scopus 로고
    • A direct measurement of the radiation sensitivity of normal mouse bone marrow cells. 1961
    • Till, J. E. and McCulloch, E. A. (2011) A direct measurement of the radiation sensitivity of normal mouse bone marrow cells. 1961. Radiat. Res., 175, 145-149.
    • (2011) Radiat. Res. , vol.175 , pp. 145-149
    • Till, J.E.1    McCulloch, E.A.2
  • 7
    • 0034614576 scopus 로고    scopus 로고
    • Stem cells: Units of development, units of regeneration, and units in evolution
    • Weissman, I. L. (2000) Stem cells: units of development, units of regeneration, and units in evolution. Cell, 100, 1, 157-168.
    • (2000) Cell , vol.100 , Issue.1 , pp. 157-168
    • Weissman, I.L.1
  • 9
    • 0029796633 scopus 로고    scopus 로고
    • Long-term lymphohematopoietic reconstitution by a single CD34-low/negative hematopoietic stem cell
    • Osawa, M.; Hanada, K.; Hamada, H. and Nakauchi, H. (1996) Long-term lymphohematopoietic reconstitution by a single CD34-low/negative hematopoietic stem cell. Science, 273, 242-245.
    • (1996) Science , vol.273 , pp. 242-245
    • Osawa, M.1    Hanada, K.2    Hamada, H.3    Nakauchi, H.4
  • 10
    • 0037183884 scopus 로고    scopus 로고
    • Little evidence for developmental plasticity of adult hematopoietic stem cells
    • Wagers, A. J.; Sherwood, R. I.; Christensen, J. L. and Weissman, I. L. (2002) Little evidence for developmental plasticity of adult hematopoietic stem cells. Science, 297, 2256-2259.
    • (2002) Science , vol.297 , pp. 2256-2259
    • Wagers, A.J.1    Sherwood, R.I.2    Christensen, J.L.3    Weissman, I.L.4
  • 11
    • 1642578983 scopus 로고    scopus 로고
    • Unexpectedly efficient homing capacity of purified murine hematopoietic stem cells
    • Matsuzaki, Y.; Kinjo, K.; Mulligan, R. C. and Okano, H. (2004) Unexpectedly efficient homing capacity of purified murine hematopoietic stem cells. Immunity, 20, 87-93.
    • (2004) Immunity , vol.20 , pp. 87-93
    • Matsuzaki, Y.1    Kinjo, K.2    Mulligan, R.C.3    Okano, H.4
  • 12
    • 21244463426 scopus 로고    scopus 로고
    • SLAM family receptors distinguish hematopoietic stem and progenitor cells and reveal endothelial niches for stem cells
    • Kiel, M. J.; Yilmaz, O. H.; Iwashita, T.; Terhorst, C. and Morrison, S. J. (2005) SLAM family receptors distinguish hematopoietic stem and progenitor cells and reveal endothelial niches for stem cells. Cell, 121, 1109-1121.
    • (2005) Cell , vol.121 , pp. 1109-1121
    • Kiel, M.J.1    Yilmaz, O.H.2    Iwashita, T.3    Terhorst, C.4    Morrison, S.J.5
  • 13
    • 77953512588 scopus 로고    scopus 로고
    • Heterogeneity and hierarchy within the most primitive hematopoietic stem cell compartment
    • Morita, Y.; Ema, H. and Nakauchi, H. (2010) Heterogeneity and hierarchy within the most primitive hematopoietic stem cell compartment. J. Exp. Med., 207, 1173-1182.
    • (2010) J. Exp. Med. , vol.207 , pp. 1173-1182
    • Morita, Y.1    Ema, H.2    Nakauchi, H.3
  • 18
    • 77957091302 scopus 로고    scopus 로고
    • CD31+ cells represent highly angiogenic and vasculogenic cells in bone marrow: Novel role of nonendothelial CD31+ cells in neovascularization and their therapeutic effects on ischemic vascular disease
    • Kim, H.; Cho, H. J.; Kim, S. W.; Liu, B.; Choi, Y. J.; Lee, J.; Sohn, Y. D.; Lee, M. Y.; Houge, M. A. and Yoon, Y. S. (2010) CD31+ cells represent highly angiogenic and vasculogenic cells in bone marrow: novel role of nonendothelial CD31+ cells in neovascularization and their therapeutic effects on ischemic vascular disease. Circ. Res., 107, 602-614.
    • (2010) Circ. Res. , vol.107 , pp. 602-614
    • Kim, H.1    Cho, H.J.2    Kim, S.W.3    Liu, B.4    Choi, Y.J.5    Lee, J.6    Sohn, Y.D.7    Lee, M.Y.8    Houge, M.A.9    Yoon, Y.S.10
  • 19
    • 1942517003 scopus 로고    scopus 로고
    • Haematopoietic stem cells adopt mature haematopoietic fates in ischaemic myocardium
    • Balsam, L. B.; Wagers, A. J.; Christensen, J. L.; Kofidis, T.; Weissman, I. L. and Robbins, R. C. (2004) Haematopoietic stem cells adopt mature haematopoietic fates in ischaemic myocardium. Nature, 428, 668-673.
    • (2004) Nature , vol.428 , pp. 668-673
    • Balsam, L.B.1    Wagers, A.J.2    Christensen, J.L.3    Kofidis, T.4    Weissman, I.L.5    Robbins, R.C.6
  • 21
    • 38149022647 scopus 로고    scopus 로고
    • Endothelial progenitor cells for cardiovascular regeneration
    • Kawamoto, A. and Losordo, D. W. (2008) Endothelial progenitor cells for cardiovascular regeneration. Trends Cardiovasc. Med., 18, 33-37.
    • (2008) Trends Cardiovasc. Med. , vol.18 , pp. 33-37
    • Kawamoto, A.1    Losordo, D.W.2
  • 24
    • 77956207346 scopus 로고    scopus 로고
    • Distinct kinin-induced functions are altered in circulating cells of young type 1 diabetic patients
    • Krankel, N.; Armstrong, S. P.; McArdle, C. A.; Dayan, C.; Madeddu, P. Distinct kinin-induced functions are altered in circulating cells of young type 1 diabetic patients. PloS one, 5, e11146.
    • PloS one , vol.5
    • Krankel, N.1    Armstrong, S.P.2    McArdle, C.A.3    Dayan, C.4    Madeddu, P.5
  • 26
    • 41149109622 scopus 로고    scopus 로고
    • Uncertainty in the niches that maintain haematopoietic stem cells
    • Kiel, M. J. and Morrison, S. J. (2008) Uncertainty in the niches that maintain haematopoietic stem cells. Nat. Rev. Immunol., 8, 290-301.
    • (2008) Nat. Rev. Immunol. , vol.8 , pp. 290-301
    • Kiel, M.J.1    Morrison, S.J.2
  • 27
    • 47149084029 scopus 로고    scopus 로고
    • Evolving concepts on the microenvironmental niche for hematopoietic stem cells
    • Raaijmakers, M. H. and Scadden, D. T. (2008) Evolving concepts on the microenvironmental niche for hematopoietic stem cells. Curr. Opin. Hematol., 15, 301-306.
    • (2008) Curr. Opin. Hematol. , vol.15 , pp. 301-306
    • Raaijmakers, M.H.1    Scadden, D.T.2
  • 29
    • 74449084422 scopus 로고    scopus 로고
    • Notch signaling and the bone marrow hematopoietic stem cell niche
    • Weber, J. M. and Calvi, L. M. (2010) Notch signaling and the bone marrow hematopoietic stem cell niche. Bone, 46, 281-285.
    • (2010) Bone , vol.46 , pp. 281-285
    • Weber, J.M.1    Calvi, L.M.2
  • 31
    • 0026500983 scopus 로고
    • Evidence that hematopoietic stem cells express mouse c-kit but do not depend on steel factor for their generation
    • Ikuta, K. and Weissman, I. L. (1992) Evidence that hematopoietic stem cells express mouse c-kit but do not depend on steel factor for their generation. Proc. Nat. Acad. Sci. USA, 89, 4, 1502-1506.
    • (1992) Proc. Nat. Acad. Sci. USA , vol.89 , Issue.4 , pp. 1502-1506
    • Ikuta, K.1    Weissman, I.L.2
  • 32
    • 0031058875 scopus 로고    scopus 로고
    • Impaired steel factor responsiveness differentially affects the detection and long-term maintenance of fetal liver hematopoietic stem cells
    • in vivo
    • Miller, C. L.; Rebel, V. I.; Helgason, C. D.; Lansdorp, P. M. and Eaves, C. J. (1997) Impaired steel factor responsiveness differentially affects the detection and long-term maintenance of fetal liver hematopoietic stem cells in vivo. Blood, 89, 1214-1223.
    • (1997) Blood , vol.89 , pp. 1214-1223
    • Miller, C.L.1    Rebel, V.I.2    Helgason, C.D.3    Lansdorp, P.M.4    Eaves, C.J.5
  • 33
    • 0037145641 scopus 로고    scopus 로고
    • Common and distinct features of cytokine effects on hematopoietic stem and progenitor cells revealed by dose-response surface analysis
    • Audet, J.; Miller, C. L.; Eaves, C. J. and Piret, J. M. (2002) Common and distinct features of cytokine effects on hematopoietic stem and progenitor cells revealed by dose-response surface analysis. Biotech. Bioeng., 80, 393-404.
    • (2002) Biotech. Bioeng. , vol.80 , pp. 393-404
    • Audet, J.1    Miller, C.L.2    Eaves, C.J.3    Piret, J.M.4
  • 35
    • 3242669145 scopus 로고    scopus 로고
    • Tie2/angiopoietin-1 signaling regulates hematopoietic stem cell quiescence in the bone marrow niche
    • Arai, F.; Hirao, A.; Ohmura, M.; Sato, H.; Matsuoka, S.; Takubo, K.; Ito, K.; Koh, G. Y. and Suda, T. (2004) Tie2/angiopoietin-1 signaling regulates hematopoietic stem cell quiescence in the bone marrow niche. Cell, 118, 149-161.
    • (2004) Cell , vol.118 , pp. 149-161
    • Arai, F.1    Hirao, A.2    Ohmura, M.3    Sato, H.4    Matsuoka, S.5    Takubo, K.6    Ito, K.7    Koh, G.Y.8    Suda, T.9
  • 36
    • 0006677050 scopus 로고    scopus 로고
    • Angiopoietin-1 regulates endothelial cell survival through the phosphatidylinositol 3'-Kinase/Akt signal transduction pathway
    • Kim, I.; Kim, H. G.; So, J. N.; Kim, J. H.; Kwak, H. J. and Koh, G. Y. (2000) Angiopoietin-1 regulates endothelial cell survival through the phosphatidylinositol 3'-Kinase/Akt signal transduction pathway. Circ. Res., 86, 24-29.
    • (2000) Circ. Res. , vol.86 , pp. 24-29
    • Kim, I.1    Kim, H.G.2    So, J.N.3    Kim, J.H.4    Kwak, H.J.5    Koh, G.Y.6
  • 40
    • 34547670604 scopus 로고    scopus 로고
    • Lack of evidence that hematopoietic stem cells depend on N-cadherinmediated adhesion to osteoblasts for their maintenance
    • Kiel, M. J.; Radice, G. L. and Morrison, S. J. (2007) Lack of evidence that hematopoietic stem cells depend on N-cadherinmediated adhesion to osteoblasts for their maintenance. Cell Stem Cell, 1, 204-217.
    • (2007) Cell Stem Cell , vol.1 , pp. 204-217
    • Kiel, M.J.1    Radice, G.L.2    Morrison, S.J.3
  • 43
    • 41349114265 scopus 로고    scopus 로고
    • Circadian rhythms: Stem cells traffic in time
    • Scadden, D. T. (2008) Circadian rhythms: stem cells traffic in time. Nature, 452, 416-417.
    • (2008) Nature , vol.452 , pp. 416-417
    • Scadden, D.T.1
  • 44
    • 34347258134 scopus 로고    scopus 로고
    • Autonomic innervation and regulation of the immune system (1987-2007)
    • Nance, D. M. and Sanders, V. M. (2007) Autonomic innervation and regulation of the immune system (1987-2007). Brain Behavior Immunity, 21, 736-745.
    • (2007) Brain Behavior Immunity , vol.21 , pp. 736-745
    • Nance, D.M.1    Sanders, V.M.2
  • 48
    • 0033001286 scopus 로고    scopus 로고
    • Receptor activator of NF-kappaB recruits multiple TRAF family adaptors and activates c-Jun N-terminal kinase
    • Kim, H. H.; Lee, D. E.; Shin, J. N.; Lee, Y. S.; Jeon, Y. M.; Chung, C. H.; Ni, J.; Kwon, B. S. and Lee, Z. H. (1999) Receptor activator of NF-kappaB recruits multiple TRAF family adaptors and activates c-Jun N-terminal kinase. FEBS Lett., 443, 297-302.
    • (1999) FEBS Lett. , vol.443 , pp. 297-302
    • Kim, H.H.1    Lee, D.E.2    Shin, J.N.3    Lee, Y.S.4    Jeon, Y.M.5    Chung, C.H.6    Ni, J.7    Kwon, B.S.8    Lee, Z.H.9
  • 49
    • 0037673945 scopus 로고    scopus 로고
    • Osteoclast differentiation and activation
    • Boyle, W. J.; Simonet, W. S. and Lacey, D. L. (2003) Osteoclast differentiation and activation. Nature, 423, 337-342.
    • (2003) Nature , vol.423 , pp. 337-342
    • Boyle, W.J.1    Simonet, W.S.2    Lacey, D.L.3
  • 50
    • 34247889894 scopus 로고    scopus 로고
    • The multiple roles of osteoclasts in host defense: Bone remodeling and hematopoietic stem cell mobilization
    • Kollet, O.; Dar, A. and Lapidot, T. (2007) The multiple roles of osteoclasts in host defense: bone remodeling and hematopoietic stem cell mobilization. Ann. Rev. Immunol., 25, 51-69.
    • (2007) Ann. Rev. Immunol. , vol.25 , pp. 51-69
    • Kollet, O.1    Dar, A.2    Lapidot, T.3
  • 51
    • 51249114496 scopus 로고    scopus 로고
    • The WNT signalling pathway and diabetes mellitus
    • Jin, T. (2008) The WNT signalling pathway and diabetes mellitus. Diabetologia, 51, 1771-1780.
    • (2008) Diabetologia , vol.51 , pp. 1771-1780
    • Jin, T.1
  • 52
    • 55649098154 scopus 로고    scopus 로고
    • Wnt signaling: Relevance to beta-cell biology and diabetes
    • Welters, H. J. and Kulkarni, R. N. (2008) Wnt signaling: relevance to beta-cell biology and diabetes. Trends Endocrinol. Metab., 19, 349-355.
    • (2008) Trends Endocrinol. Metab. , vol.19 , pp. 349-355
    • Welters, H.J.1    Kulkarni, R.N.2
  • 54
    • 54449089664 scopus 로고    scopus 로고
    • The Wnt antagonist Dickkopf-1 mobilizes vasculogenic progenitor cells via activation of the bone marrow endosteal stem cell niche
    • Aicher, A.; Kollet, O.; Heeschen, C.; Liebner, S.; Urbich, C.; Ihling, C.; Orlandi, A.; Lapidot, T.; Zeiher, A. M. and Dimmeler, S. (2008) The Wnt antagonist Dickkopf-1 mobilizes vasculogenic progenitor cells via activation of the bone marrow endosteal stem cell niche. Circ. Res., 103, 796-803.
    • (2008) Circ. Res. , vol.103 , pp. 796-803
    • Aicher, A.1    Kollet, O.2    Heeschen, C.3    Liebner, S.4    Urbich, C.5    Ihling, C.6    Orlandi, A.7    Lapidot, T.8    Zeiher, A.M.9    Dimmeler, S.10
  • 55
    • 34248359065 scopus 로고    scopus 로고
    • Distribution of hematopoietic stem cells in the bone marrow according to regional hypoxia
    • Parmar, K.; Mauch, P.; Vergilio, J. A.; Sackstein, R. and Down, J. D. (2007) Distribution of hematopoietic stem cells in the bone marrow according to regional hypoxia. Proc. Natl. Acad. Sci. USA, 104, 5431-5436.
    • (2007) Proc. Natl. Acad. Sci. USA , vol.104 , pp. 5431-5436
    • Parmar, K.1    Mauch, P.2    Vergilio, J.A.3    Sackstein, R.4    Down, J.D.5
  • 56
    • 0025655510 scopus 로고
    • Cell sorting with Hoechst or carbocyanine dyes as perfusion probes in spheroids and tumors
    • Durand, R. E.; Chaplin, D. J. and Olive, P. L. (1990) Cell sorting with Hoechst or carbocyanine dyes as perfusion probes in spheroids and tumors. Methods Cell Biol., 33, 509-518.
    • (1990) Methods Cell Biol. , vol.33 , pp. 509-518
    • Durand, R.E.1    Chaplin, D.J.2    Olive, P.L.3
  • 57
    • 20044376702 scopus 로고    scopus 로고
    • The pathobiology of diabetic complications: A unifying mechanism
    • Brownlee, M. (2005) The pathobiology of diabetic complications: a unifying mechanism. Diabetes, 54, 1615-1625.
    • (2005) Diabetes , vol.54 , pp. 1615-1625
    • Brownlee, M.1
  • 58
    • 0348048874 scopus 로고    scopus 로고
    • Diabetic retinopathy
    • Frank, R. N. (2004) Diabetic retinopathy. N. Engl. J. Med., 350, 48-58.
    • (2004) N. Engl. J. Med. , vol.350 , pp. 48-58
    • Frank, R.N.1
  • 60
    • 79955953053 scopus 로고    scopus 로고
    • A potential role for angiopoietin 2 in the regulation of the blood-retinal barrier in diabetic retinopathy
    • Rangasamy, S.; Srinivasan, R.; Maestas, J.; McGuire, P. G. and Das, A. (2011) A potential role for angiopoietin 2 in the regulation of the blood-retinal barrier in diabetic retinopathy. Invest. Ophthalmol. Vis. Sci., 52, 3784-3791.
    • (2011) Invest. Ophthalmol. Vis. Sci. , vol.52 , pp. 3784-3791
    • Rangasamy, S.1    Srinivasan, R.2    Maestas, J.3    McGuire, P.G.4    Das, A.5
  • 61
    • 0036174019 scopus 로고    scopus 로고
    • Retinal vascular endothelial growth factor induces intercellular adhesion molecule-1 and endothelial nitric oxide synthase expression and initiates early diabetic retinal leukocyte adhesion
    • in vivo
    • Joussen, A. M.; Poulaki, V.; Qin, W.; Kirchhof, B.; Mitsiades, N.; Wiegand, S. J.; Rudge, J.; Yancopoulos, G. D. and Adamis, A. P. (2002) Retinal vascular endothelial growth factor induces intercellular adhesion molecule-1 and endothelial nitric oxide synthase expression and initiates early diabetic retinal leukocyte adhesion in vivo. Am. J. Pathol., 160, 501-509.
    • (2002) Am. J. Pathol. , vol.160 , pp. 501-509
    • Joussen, A.M.1    Poulaki, V.2    Qin, W.3    Kirchhof, B.4    Mitsiades, N.5    Wiegand, S.J.6    Rudge, J.7    Yancopoulos, G.D.8    Adamis, A.P.9
  • 62
    • 23244435467 scopus 로고    scopus 로고
    • How do stem cells find their way home?
    • Lapidot, T.; Dar, A. and Kollet, O. (2005) How do stem cells find their way home? Blood, 106, 1901-1910.
    • (2005) Blood , vol.106 , pp. 1901-1910
    • Lapidot, T.1    Dar, A.2    Kollet, O.3
  • 63
    • 0026003329 scopus 로고
    • Diabetic bone disease
    • Bouillon, R. (1991) Diabetic bone disease. Calcif. Tissue Int., 49, 155-160.
    • (1991) Calcif. Tissue Int. , vol.49 , pp. 155-160
    • Bouillon, R.1
  • 64
    • 0344736959 scopus 로고    scopus 로고
    • Diabetes mellitus: Does it affect bone?
    • Schwartz, A. V. (2003) Diabetes mellitus: Does it affect bone? Calcif. Tissue Int., 73, 515-519.
    • (2003) Calcif. Tissue Int. , vol.73 , pp. 515-519
    • Schwartz, A.V.1
  • 65
    • 0033933211 scopus 로고    scopus 로고
    • Osteopenia in insulin-dependent diabetes mellitus; prevalence and aspects of pathophysiology
    • Kemink, S. A.; Hermus, A. R.; Swinkels, L. M.; Lutterman, J. A. and Smals, A. G. (2000) Osteopenia in insulin-dependent diabetes mellitus; prevalence and aspects of pathophysiology. J. Endocrinol. Invest., 23, 295-303.
    • (2000) J. Endocrinol. Invest. , vol.23 , pp. 295-303
    • Kemink, S.A.1    Hermus, A.R.2    Swinkels, L.M.3    Lutterman, J.A.4    Smals, A.G.5
  • 69
    • 0032977597 scopus 로고    scopus 로고
    • Bone mineral density in patients with type 1 and type 2 diabetes
    • Tuominen, J. T.; Impivaara, O.; Puukka, P. and Ronnemaa, T. (1999) Bone mineral density in patients with type 1 and type 2 diabetes. Diabetes Care, 22, 1196-1200.
    • (1999) Diabetes Care , vol.22 , pp. 1196-1200
    • Tuominen, J.T.1    Impivaara, O.2    Puukka, P.3    Ronnemaa, T.4
  • 71
    • 36148996151 scopus 로고    scopus 로고
    • Increased cathepsin K and tartrate-resistant acid phosphatase expression in bone of streptozotocin-induced diabetic rats
    • Hie, M.; Shimono, M.; Fujii, K.; Tsukamoto, I. (2007) Increased cathepsin K and tartrate-resistant acid phosphatase expression in bone of streptozotocin-induced diabetic rats. Bone, 41, 1045-1050.
    • (2007) Bone , vol.41 , pp. 1045-1050
    • Hie, M.1    Shimono, M.2    Fujii, K.3    Tsukamoto, I.4
  • 72
    • 77957858845 scopus 로고    scopus 로고
    • Increased expression of the receptor for activation of NF-kappaB and decreased runt-related transcription factor 2 expression in bone of rats with streptozotocininduced diabetes
    • Hie, M. and Tsukamoto, I. (2010) Increased expression of the receptor for activation of NF-kappaB and decreased runt-related transcription factor 2 expression in bone of rats with streptozotocininduced diabetes. Internat. J. Mol. Med., 26, 611-618.
    • (2010) Internat. J. Mol. Med. , vol.26 , pp. 611-618
    • Hie, M.1    Tsukamoto, I.2
  • 73
    • 36849045166 scopus 로고    scopus 로고
    • Understanding the pathology and mechanisms of type I diabetic bone loss
    • McCabe, L. R. (2007) Understanding the pathology and mechanisms of type I diabetic bone loss. J. Cell. Biochem., 102, 1343-1357.
    • (2007) J. Cell. Biochem. , vol.102 , pp. 1343-1357
    • McCabe, L.R.1
  • 75
    • 35548936968 scopus 로고    scopus 로고
    • A low level of reactive oxygen species selects for primitive hematopoietic stem cells that may reside in the low-oxygenic niche
    • Jang, Y. Y. and Sharkis, S. J. (2007) A low level of reactive oxygen species selects for primitive hematopoietic stem cells that may reside in the low-oxygenic niche. Blood, 110, 3056-3063.
    • (2007) Blood , vol.110 , pp. 3056-3063
    • Jang, Y.Y.1    Sharkis, S.J.2
  • 81
    • 34248213008 scopus 로고    scopus 로고
    • Diabetic impairments in NO-mediated endothelial progenitor cell mobilization and homing are reversed by hyperoxia and SDF-1 alpha
    • Gallagher, K. A.; Liu, Z. J.; Xiao, M.; Chen, H.; Goldstein, L. J.; Buerk, D. G.; Nedeau, A.; Thom, S. R. and Velazquez, O. C. (2007) Diabetic impairments in NO-mediated endothelial progenitor cell mobilization and homing are reversed by hyperoxia and SDF-1 alpha. J. Clin. Invest., 117, 1249-1259.
    • (2007) J. Clin. Invest. , vol.117 , pp. 1249-1259
    • Gallagher, K.A.1    Liu, Z.J.2    Xiao, M.3    Chen, H.4    Goldstein, L.J.5    Buerk, D.G.6    Nedeau, A.7    Thom, S.R.8    Velazquez, O.C.9
  • 82
    • 33847346061 scopus 로고    scopus 로고
    • Endothelial nitric oxide synthase uncoupling impairs endothelial progenitor cell mobilization and function in diabetes
    • Thum, T.; Fraccarollo, D.; Schultheiss, M.; Froese, S.; Galuppo, P.; Widder, J. D.; Tsikas, D.; Ertl, G. and Bauersachs, J. (2007) Endothelial nitric oxide synthase uncoupling impairs endothelial progenitor cell mobilization and function in diabetes. Diabetes, 56, 666-674.
    • (2007) Diabetes , vol.56 , pp. 666-674
    • Thum, T.1    Fraccarollo, D.2    Schultheiss, M.3    Froese, S.4    Galuppo, P.5    Widder, J.D.6    Tsikas, D.7    Ertl, G.8    Bauersachs, J.9
  • 83
    • 72449157983 scopus 로고    scopus 로고
    • Decreased mobilization of endothelial progenitor cells contributes to impaired neovascularization in diabetes
    • Kang, L.; Chen, Q.; Wang, L.; Gao, L.; Meng, K.; Chen, J.; Ferro, A. and Xu, B. (2009) Decreased mobilization of endothelial progenitor cells contributes to impaired neovascularization in diabetes. Clin. Exp. Pharmacol. Physiol., 36, e47-e56.
    • (2009) Clin. Exp. Pharmacol. Physiol. , vol.36
    • Kang, L.1    Chen, Q.2    Wang, L.3    Gao, L.4    Meng, K.5    Chen, J.6    Ferro, A.7    Xu, B.8
  • 87
    • 78650510515 scopus 로고    scopus 로고
    • Targeting stem cell niches and trafficking for cardiovascular therapy
    • Krankel, N.; Spinetti, G.; Amadesi, S. and Madeddu, P. (2011) Targeting stem cell niches and trafficking for cardiovascular therapy. Pharmacol. Ther., 129, 62-81.
    • (2011) Pharmacol. Ther. , vol.129 , pp. 62-81
    • Krankel, N.1    Spinetti, G.2    Amadesi, S.3    Madeddu, P.4
  • 90
    • 33847741718 scopus 로고    scopus 로고
    • Progenitor cells and age: Can we fight aging with exercise?
    • Witkowski, S. and Hagberg, J. M. (2007) Progenitor cells and age: can we fight aging with exercise? J. Appl. Physiol., 102, 834-835.
    • (2007) J. Appl. Physiol. , vol.102 , pp. 834-835
    • Witkowski, S.1    Hagberg, J.M.2
  • 91
    • 77958195997 scopus 로고    scopus 로고
    • The oral dipeptidyl peptidase-4 inhibitor sitagliptin increases circulating endothelial progenitor cells in patients with type 2 diabetes: Possible role of stromal-derived factor-1alpha
    • Fadini, G. P.; Boscaro, E.; Albiero, M.; Menegazzo, L.; Frison, V.; de Kreutzenberg, S.; Agostini, C.; Tiengo, A. and Avogaro, A. (2010) The oral dipeptidyl peptidase-4 inhibitor sitagliptin increases circulating endothelial progenitor cells in patients with type 2 diabetes: possible role of stromal-derived factor-1alpha. Diabetes Care, 33, 1607-1609.
    • (2010) Diabetes Care , vol.33 , pp. 1607-1609
    • Fadini, G.P.1    Boscaro, E.2    Albiero, M.3    Menegazzo, L.4    Frison, V.5    de Kreutzenberg, S.6    Agostini, C.7    Tiengo, A.8    Avogaro, A.9


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