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Volumn 46, Issue 2, 2010, Pages 281-285

Notch signaling and the bone marrow hematopoietic stem cell niche

Author keywords

Hematopoietic stem cells; Microenvironment; Niche; Notch signaling; Osteblasts

Indexed keywords

COLLAGEN TYPE 1; GAMMA SECRETASE; JAGGED1; MEMBRANE PROTEIN; NOTCH RECEPTOR; NOTCH1 RECEPTOR; NOTCH2 RECEPTOR; NOTCH3 RECEPTOR; NOTCH4 RECEPTOR; TUMOR NECROSIS FACTOR ALPHA CONVERTING ENZYME;

EID: 74449084422     PISSN: 87563282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bone.2009.08.007     Document Type: Review
Times cited : (99)

References (73)
  • 1
    • 0018102359 scopus 로고
    • The relationship between the spleen colony-forming cell and the haemopoietic stem cell
    • Schofield R. The relationship between the spleen colony-forming cell and the haemopoietic stem cell. Blood Cells 4 (1978) 7-25
    • (1978) Blood Cells , vol.4 , pp. 7-25
    • Schofield, R.1
  • 3
    • 0033617522 scopus 로고    scopus 로고
    • Notch signaling: cell fate control and signal integration in development
    • Artavanis-Tsakonas S., Rand M.D., and Lake R.J. Notch signaling: cell fate control and signal integration in development. Science 284 (1999) 770-776
    • (1999) Science , vol.284 , pp. 770-776
    • Artavanis-Tsakonas, S.1    Rand, M.D.2    Lake, R.J.3
  • 4
    • 42749089216 scopus 로고    scopus 로고
    • Communications between bone cells and hematopoietic stem cells
    • Porter R.L., and Calvi L.M. Communications between bone cells and hematopoietic stem cells. Arch. Biochem. Biophys. 473 (2008) 193-200
    • (2008) Arch. Biochem. Biophys. , vol.473 , pp. 193-200
    • Porter, R.L.1    Calvi, L.M.2
  • 5
    • 0031883380 scopus 로고    scopus 로고
    • The role of osteoblasts in the hematopoietic microenvironment
    • Taichman R.S., and Emerson S.G. The role of osteoblasts in the hematopoietic microenvironment. Stem Cells 16 (1998) 7-15
    • (1998) Stem Cells , vol.16 , pp. 7-15
    • Taichman, R.S.1    Emerson, S.G.2
  • 6
    • 0023636264 scopus 로고
    • Analysis of DNA surrounding the breakpoints of chromosomal translocations involving the beta T cell receptor gene in human lymphoblastic neoplasms
    • Reynolds T.C., Smith S.D., and Sklar J. Analysis of DNA surrounding the breakpoints of chromosomal translocations involving the beta T cell receptor gene in human lymphoblastic neoplasms. Cell 50 (1987) 107-117
    • (1987) Cell , vol.50 , pp. 107-117
    • Reynolds, T.C.1    Smith, S.D.2    Sklar, J.3
  • 7
    • 0025856717 scopus 로고
    • TAN-1, the human homolog of the Drosophila notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms
    • Ellisen L.W., Bird J., West D.C., Soreng A.L., Reynolds T.C., Smith S.D., et al. TAN-1, the human homolog of the Drosophila notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms. Cell 66 (1991) 649-661
    • (1991) Cell , vol.66 , pp. 649-661
    • Ellisen, L.W.1    Bird, J.2    West, D.C.3    Soreng, A.L.4    Reynolds, T.C.5    Smith, S.D.6
  • 8
    • 40449139405 scopus 로고    scopus 로고
    • Dimorphic effects of Notch signaling in bone homeostasis
    • Engin F., Yao Z., Yang T., Zhou G., Bertin T., Jiang M.M., et al. Dimorphic effects of Notch signaling in bone homeostasis. Nat. Med. 14 (2008) 299-305
    • (2008) Nat. Med. , vol.14 , pp. 299-305
    • Engin, F.1    Yao, Z.2    Yang, T.3    Zhou, G.4    Bertin, T.5    Jiang, M.M.6
  • 9
    • 40449084522 scopus 로고    scopus 로고
    • Notch signaling maintains bone marrow mesenchymal progenitors by suppressing osteoblast differentiation
    • Hilton M.J., Tu X., Wu X., Bai S., Zhao H., Kobayashi T., et al. Notch signaling maintains bone marrow mesenchymal progenitors by suppressing osteoblast differentiation. Nat. Med. 14 (2008) 306-314
    • (2008) Nat. Med. , vol.14 , pp. 306-314
    • Hilton, M.J.1    Tu, X.2    Wu, X.3    Bai, S.4    Zhao, H.5    Kobayashi, T.6
  • 11
    • 0037376416 scopus 로고    scopus 로고
    • An overview of the Notch signalling pathway. Semin
    • M. Baron. An overview of the Notch signalling pathway. Semin. Cell Dev Biol l2003;14: 113-119
    • Cell Dev Biol l2003;14 , pp. 113-119
    • Baron, M.1
  • 12
    • 0036727125 scopus 로고    scopus 로고
    • Gamma-secretase-mediated proteolysis in cell-surface-receptor signalling
    • Fortini M.E. Gamma-secretase-mediated proteolysis in cell-surface-receptor signalling. Nat. Rev. Mol. Cell Biol. 3 (2002) 673-684
    • (2002) Nat. Rev. Mol. Cell Biol. , vol.3 , pp. 673-684
    • Fortini, M.E.1
  • 13
    • 0033524444 scopus 로고    scopus 로고
    • CIR, a corepressor linking the DNA binding factor CBF1 to the histone deacetylase complex
    • Hsieh J.J., Zhou S., Chen L., Young D.B., and Hayward S.D. CIR, a corepressor linking the DNA binding factor CBF1 to the histone deacetylase complex. Proc. Natl. Acad. Sci. U. S. A. 96 (1999) 23-28
    • (1999) Proc. Natl. Acad. Sci. U. S. A. , vol.96 , pp. 23-28
    • Hsieh, J.J.1    Zhou, S.2    Chen, L.3    Young, D.B.4    Hayward, S.D.5
  • 14
    • 0032145527 scopus 로고    scopus 로고
    • A histone deacetylase corepressor complex regulates the Notch signal transduction pathway
    • Kao H.Y., Ordentlich P., Koyano-Nakagawa N., Tang Z., Downes M., Kintner C.R., et al. A histone deacetylase corepressor complex regulates the Notch signal transduction pathway. Genes Dev. 12 (1998) 2269-2277
    • (1998) Genes Dev. , vol.12 , pp. 2269-2277
    • Kao, H.Y.1    Ordentlich, P.2    Koyano-Nakagawa, N.3    Tang, Z.4    Downes, M.5    Kintner, C.R.6
  • 15
    • 0034073379 scopus 로고    scopus 로고
    • SKIP, a CBF1-associated protein, interacts with the ankyrin repeat domain of NotchIC To facilitate NotchIC function
    • Zhou S., Fujimuro M., Hsieh J.J., Chen L., Miyamoto A., Weinmaster G., et al. SKIP, a CBF1-associated protein, interacts with the ankyrin repeat domain of NotchIC To facilitate NotchIC function. Mol. Cell. Biol. 20 (2000) 2400-2410
    • (2000) Mol. Cell. Biol. , vol.20 , pp. 2400-2410
    • Zhou, S.1    Fujimuro, M.2    Hsieh, J.J.3    Chen, L.4    Miyamoto, A.5    Weinmaster, G.6
  • 16
    • 0033662392 scopus 로고    scopus 로고
    • MAML1, a human homologue of Drosophila mastermind, is a transcriptional co-activator for NOTCH receptors
    • Wu L., Aster J.C., Blacklow S.C., Lake R., Artavanis-Tsakonas S., and Griffin J.D. MAML1, a human homologue of Drosophila mastermind, is a transcriptional co-activator for NOTCH receptors. Nat. Genet. 26 (2000) 484-489
    • (2000) Nat. Genet. , vol.26 , pp. 484-489
    • Wu, L.1    Aster, J.C.2    Blacklow, S.C.3    Lake, R.4    Artavanis-Tsakonas, S.5    Griffin, J.D.6
  • 17
    • 0036096912 scopus 로고    scopus 로고
    • Characterization of a high-molecular-weight Notch complex in the nucleus of Notch(ic)-transformed RKE cells and in a human T-cell leukemia cell line
    • Jeffries S., Robbins D.J., and Capobianco A.J. Characterization of a high-molecular-weight Notch complex in the nucleus of Notch(ic)-transformed RKE cells and in a human T-cell leukemia cell line. Mol. Cell. Biol. 22 (2002) 3927-3941
    • (2002) Mol. Cell. Biol. , vol.22 , pp. 3927-3941
    • Jeffries, S.1    Robbins, D.J.2    Capobianco, A.J.3
  • 18
    • 0029942842 scopus 로고    scopus 로고
    • Exclusive development of T cell neoplasms in mice transplanted with bone marrow expressing activated Notch alleles
    • Pear W.S., Aster J.C., Scott M.L., Hasserjian R.P., Soffer B., Sklar J., et al. Exclusive development of T cell neoplasms in mice transplanted with bone marrow expressing activated Notch alleles. J. Exp. Med. 183 (1996) 2283-2291
    • (1996) J. Exp. Med. , vol.183 , pp. 2283-2291
    • Pear, W.S.1    Aster, J.C.2    Scott, M.L.3    Hasserjian, R.P.4    Soffer, B.5    Sklar, J.6
  • 19
    • 0033681301 scopus 로고    scopus 로고
    • Notch1 signaling promotes the maturation of CD4 and CD8 SP thymocytes
    • Deftos M.L., Huang E., Ojala E.W., Forbush K.A., and Bevan M.J. Notch1 signaling promotes the maturation of CD4 and CD8 SP thymocytes. Immunity 13 (2000) 73-84
    • (2000) Immunity , vol.13 , pp. 73-84
    • Deftos, M.L.1    Huang, E.2    Ojala, E.W.3    Forbush, K.A.4    Bevan, M.J.5
  • 20
    • 0034600850 scopus 로고    scopus 로고
    • Constitutive activation of NF-kappaB and T-cell leukemia/lymphoma in Notch3 transgenic mice
    • Bellavia D., Campese A.F., Alesse E., Vacca A., Felli M.P., Balestri A., et al. Constitutive activation of NF-kappaB and T-cell leukemia/lymphoma in Notch3 transgenic mice. EMBO J. 19 (2000) 3337-3348
    • (2000) EMBO J. , vol.19 , pp. 3337-3348
    • Bellavia, D.1    Campese, A.F.2    Alesse, E.3    Vacca, A.4    Felli, M.P.5    Balestri, A.6
  • 22
    • 44749092573 scopus 로고    scopus 로고
    • Notchsignaling in CD4 and CD8 T cell development
    • Laky K., and Fowlkes B.J. Notchsignaling in CD4 and CD8 T cell development. Curr. Opin. Immunol. 20 (2008) 197-202
    • (2008) Curr. Opin. Immunol. , vol.20 , pp. 197-202
    • Laky, K.1    Fowlkes, B.J.2
  • 23
    • 33751090056 scopus 로고    scopus 로고
    • NOTCH1 mutations are rare in acute myeloid leukemia
    • Fu L., Kogoshi H., Nara N., and Tohda S. NOTCH1 mutations are rare in acute myeloid leukemia. Leuk. Lymphoma 47 (2006) 2400-2403
    • (2006) Leuk. Lymphoma , vol.47 , pp. 2400-2403
    • Fu, L.1    Kogoshi, H.2    Nara, N.3    Tohda, S.4
  • 24
    • 47649118102 scopus 로고    scopus 로고
    • Notch-dependent control of myelopoiesis is regulated by fucosylation
    • Zhou L., Li L.W., Yan Q., Petryniak B., Man Y., Su C., et al. Notch-dependent control of myelopoiesis is regulated by fucosylation. Blood 112 (2008) 308-319
    • (2008) Blood , vol.112 , pp. 308-319
    • Zhou, L.1    Li, L.W.2    Yan, Q.3    Petryniak, B.4    Man, Y.5    Su, C.6
  • 25
    • 30444457864 scopus 로고    scopus 로고
    • Notch signaling in hematopoiesis and lymphopoiesis: lessons from Drosophila
    • Radtke F., Wilson A., and MacDonald H.R. Notch signaling in hematopoiesis and lymphopoiesis: lessons from Drosophila. BioEssays 27 (2005) 1117-1128
    • (2005) BioEssays , vol.27 , pp. 1117-1128
    • Radtke, F.1    Wilson, A.2    MacDonald, H.R.3
  • 27
    • 0033694305 scopus 로고    scopus 로고
    • Pluripotent, cytokine-dependent, hematopoietic stem cells are immortalized by constitutive Notch1 signaling
    • Varnum-Finney B., Xu L., Brashem-Stein C., Nourigat C., Flowers D., Bakkour S., et al. Pluripotent, cytokine-dependent, hematopoietic stem cells are immortalized by constitutive Notch1 signaling. Nat. Med. 6 (2000) 1278-1281
    • (2000) Nat. Med. , vol.6 , pp. 1278-1281
    • Varnum-Finney, B.1    Xu, L.2    Brashem-Stein, C.3    Nourigat, C.4    Flowers, D.5    Bakkour, S.6
  • 28
    • 0036529989 scopus 로고    scopus 로고
    • Notch1 activation increases hematopoietic stem cell self-renewal in vivo and favors lymphoid over myeloid lineage outcome
    • Stier S., Cheng T., Dombkowski D., Carlesso N., and Scadden D.T. Notch1 activation increases hematopoietic stem cell self-renewal in vivo and favors lymphoid over myeloid lineage outcome. Blood 99 (2002) 2369-2378
    • (2002) Blood , vol.99 , pp. 2369-2378
    • Stier, S.1    Cheng, T.2    Dombkowski, D.3    Carlesso, N.4    Scadden, D.T.5
  • 31
    • 33947415689 scopus 로고    scopus 로고
    • Increased Notch 1 expression and attenuated stimulatory G protein coupling to adenylyl cyclase in osteonectin-null osteoblasts
    • Kessler C.B., and Delany A.M. Increased Notch 1 expression and attenuated stimulatory G protein coupling to adenylyl cyclase in osteonectin-null osteoblasts. Endocrinology 148 (2007) 1666-1674
    • (2007) Endocrinology , vol.148 , pp. 1666-1674
    • Kessler, C.B.1    Delany, A.M.2
  • 34
    • 18144384703 scopus 로고    scopus 로고
    • Critical regulation of bone morphogenetic protein-induced osteoblastic differentiation by Delta1/Jagged1-activated Notch1 signaling
    • Nobta M., Tsukazaki T., Shibata Y., Xin C., Moriishi T., Sakano S., et al. Critical regulation of bone morphogenetic protein-induced osteoblastic differentiation by Delta1/Jagged1-activated Notch1 signaling. J. Biol. Chem. 280 (2005) 15842-15848
    • (2005) J. Biol. Chem. , vol.280 , pp. 15842-15848
    • Nobta, M.1    Tsukazaki, T.2    Shibata, Y.3    Xin, C.4    Moriishi, T.5    Sakano, S.6
  • 35
    • 33746652583 scopus 로고    scopus 로고
    • Parathyroid hormone stimulates expression of the Notch ligand Jagged1 in osteoblastic cells
    • Weber J.M., Forsythe S.R., Christianson C.A., Frisch B.J., Gigliotti B.J., Jordan C.T., et al. Parathyroid hormone stimulates expression of the Notch ligand Jagged1 in osteoblastic cells. Bone 39 (2006) 485-493
    • (2006) Bone , vol.39 , pp. 485-493
    • Weber, J.M.1    Forsythe, S.R.2    Christianson, C.A.3    Frisch, B.J.4    Gigliotti, B.J.5    Jordan, C.T.6
  • 36
    • 53049106277 scopus 로고    scopus 로고
    • Connective tissue growth factor enhances osteoblastogenesis in vitro
    • Smerdel-Ramoya A., Zanotti S., Deregowski V., and Canalis E. Connective tissue growth factor enhances osteoblastogenesis in vitro. J. Biol. Chem. 283 (2008) 22690-22699
    • (2008) J. Biol. Chem. , vol.283 , pp. 22690-22699
    • Smerdel-Ramoya, A.1    Zanotti, S.2    Deregowski, V.3    Canalis, E.4
  • 37
    • 0142026227 scopus 로고    scopus 로고
    • Osteogenic differentiation of the mesenchymal progenitor cells, Kusa is suppressed by Notch signaling
    • Shindo K., Kawashima N., Sakamoto K., Yamaguchi A., Umezawa A., Takagi M., et al. Osteogenic differentiation of the mesenchymal progenitor cells, Kusa is suppressed by Notch signaling. Exp. Cell Res. 290 (2003) 370-380
    • (2003) Exp. Cell Res. , vol.290 , pp. 370-380
    • Shindo, K.1    Kawashima, N.2    Sakamoto, K.3    Yamaguchi, A.4    Umezawa, A.5    Takagi, M.6
  • 38
    • 33746450835 scopus 로고    scopus 로고
    • Role of the RAM domain and ankyrin repeats on notch signaling and activity in cells of osteoblastic lineage
    • Deregowski V., Gazzerro E., Priest L., Rydziel S., and Canalis E. Role of the RAM domain and ankyrin repeats on notch signaling and activity in cells of osteoblastic lineage. J. Bone Miner. Res. 21 (2006) 1317-1326
    • (2006) J. Bone Miner. Res. , vol.21 , pp. 1317-1326
    • Deregowski, V.1    Gazzerro, E.2    Priest, L.3    Rydziel, S.4    Canalis, E.5
  • 44
    • 0037443389 scopus 로고    scopus 로고
    • Regulation of osteoclast development by Notch signaling directed to osteoclast precursors and through stromal cells
    • Yamada T., Yamazaki H., Yamane T., Yoshino M., Okuyama H., Tsuneto M., et al. Regulation of osteoclast development by Notch signaling directed to osteoclast precursors and through stromal cells. Blood 101 (2003) 2227-2234
    • (2003) Blood , vol.101 , pp. 2227-2234
    • Yamada, T.1    Yamazaki, H.2    Yamane, T.3    Yoshino, M.4    Okuyama, H.5    Tsuneto, M.6
  • 45
    • 42749095897 scopus 로고    scopus 로고
    • NOTCH1 regulates osteoclastogenesis directly in osteoclast precursors and indirectly via osteoblast lineage cells
    • Bai S., Kopan R., Zou W., Hilton M.J., Ong C.T., Long F., et al. NOTCH1 regulates osteoclastogenesis directly in osteoclast precursors and indirectly via osteoblast lineage cells. J. Biol. Chem. 283 (2008) 6509-6518
    • (2008) J. Biol. Chem. , vol.283 , pp. 6509-6518
    • Bai, S.1    Kopan, R.2    Zou, W.3    Hilton, M.J.4    Ong, C.T.5    Long, F.6
  • 47
    • 34247382563 scopus 로고    scopus 로고
    • Notch signaling controls germline stem cell niche formation in the Drosophila ovary
    • Song X., Call G.B., Kirilly D., and Xie T. Notch signaling controls germline stem cell niche formation in the Drosophila ovary. Development 134 (2007) 1071-1080
    • (2007) Development , vol.134 , pp. 1071-1080
    • Song, X.1    Call, G.B.2    Kirilly, D.3    Xie, T.4
  • 50
    • 0242363225 scopus 로고    scopus 로고
    • Identification of the haematopoietic stem cell niche and control of the niche size
    • Zhang J., Niu C., Ye L., Huang H., He X., Tong W.G., et al. Identification of the haematopoietic stem cell niche and control of the niche size. Nature 425 (2003) 836-841
    • (2003) Nature , vol.425 , pp. 836-841
    • Zhang, J.1    Niu, C.2    Ye, L.3    Huang, H.4    He, X.5    Tong, W.G.6
  • 51
    • 1942457308 scopus 로고    scopus 로고
    • Hematopoiesis is severely altered in mice with an induced osteoblast deficiency
    • Visnjic D., Kalajzic Z., Rowe D.W., Katavic V., Lorenzo J., and Aguila H.L. Hematopoiesis is severely altered in mice with an induced osteoblast deficiency. Blood 103 (2004) 3258-3264
    • (2004) Blood , vol.103 , pp. 3258-3264
    • Visnjic, D.1    Kalajzic, Z.2    Rowe, D.W.3    Katavic, V.4    Lorenzo, J.5    Aguila, H.L.6
  • 52
    • 36448933808 scopus 로고    scopus 로고
    • Beyond angiogenesis: the role of endothelium in the bone marrow vascular niche
    • Colmone A., and Sipkins D.A. Beyond angiogenesis: the role of endothelium in the bone marrow vascular niche. Transl. Res. 151 (2008) 1-9
    • (2008) Transl. Res. , vol.151 , pp. 1-9
    • Colmone, A.1    Sipkins, D.A.2
  • 53
    • 0034613734 scopus 로고    scopus 로고
    • The notch ligand jagged-1 represents a novel growth factor of human hematopoietic stem cells
    • Karanu F.N., Murdoch B., Gallacher L., Wu D.M., Koremoto M., Sakano S., et al. The notch ligand jagged-1 represents a novel growth factor of human hematopoietic stem cells. J. Exp. Med. 192 (2000) 1365-1372
    • (2000) J. Exp. Med. , vol.192 , pp. 1365-1372
    • Karanu, F.N.1    Murdoch, B.2    Gallacher, L.3    Wu, D.M.4    Koremoto, M.5    Sakano, S.6
  • 54
    • 0038780165 scopus 로고    scopus 로고
    • Differential response of primitive human CD34- and CD34+ hematopoietic cells to the Notch ligand Jagged-1
    • Karanu F.N., Yuefei L., Gallacher L., Sakano S., and Bhatia M. Differential response of primitive human CD34- and CD34+ hematopoietic cells to the Notch ligand Jagged-1. Leukemia 17 (2003) 1366-1374
    • (2003) Leukemia , vol.17 , pp. 1366-1374
    • Karanu, F.N.1    Yuefei, L.2    Gallacher, L.3    Sakano, S.4    Bhatia, M.5
  • 55
    • 0035313174 scopus 로고    scopus 로고
    • Human homologues of Delta-1 and Delta-4 function as mitogenic regulators of primitive human hematopoietic cells
    • Karanu F.N., Murdoch B., Miyabayashi T., Ohno M., Koremoto M., Gallacher L., et al. Human homologues of Delta-1 and Delta-4 function as mitogenic regulators of primitive human hematopoietic cells. Blood 97 (2001) 1960-1967
    • (2001) Blood , vol.97 , pp. 1960-1967
    • Karanu, F.N.1    Murdoch, B.2    Miyabayashi, T.3    Ohno, M.4    Koremoto, M.5    Gallacher, L.6
  • 56
    • 0032101002 scopus 로고    scopus 로고
    • The Notch ligand, Jagged-1, influences the development of primitive hematopoietic precursor cells
    • Varnum-Finney B., Purton L.E., Yu M., Brashem-Stein C., Flowers D., Staats S., et al. The Notch ligand, Jagged-1, influences the development of primitive hematopoietic precursor cells. Blood 91 (1998) 4084-4091
    • (1998) Blood , vol.91 , pp. 4084-4091
    • Varnum-Finney, B.1    Purton, L.E.2    Yu, M.3    Brashem-Stein, C.4    Flowers, D.5    Staats, S.6
  • 57
    • 0037370834 scopus 로고    scopus 로고
    • Combined effects of Notch signaling and cytokines induce a multiple log increase in precursors with lymphoid and myeloid reconstituting ability
    • Varnum-Finney B., Brashem-Stein C., and Bernstein I.D. Combined effects of Notch signaling and cytokines induce a multiple log increase in precursors with lymphoid and myeloid reconstituting ability. Blood 101 (2003) 1784-1789
    • (2003) Blood , vol.101 , pp. 1784-1789
    • Varnum-Finney, B.1    Brashem-Stein, C.2    Bernstein, I.D.3
  • 58
    • 0032904239 scopus 로고    scopus 로고
    • Notch1-induced delay of human hematopoietic progenitor cell differentiation is associated with altered cell cycle kinetics
    • Carlesso N., Aster J.C., Sklar J., and Scadden D.T. Notch1-induced delay of human hematopoietic progenitor cell differentiation is associated with altered cell cycle kinetics. Blood 93 (1999) 838-848
    • (1999) Blood , vol.93 , pp. 838-848
    • Carlesso, N.1    Aster, J.C.2    Sklar, J.3    Scadden, D.T.4
  • 59
    • 0036802174 scopus 로고    scopus 로고
    • Delta-1 enhances marrow and thymus repopulating ability of human CD34(+)CD38(-) cord blood cells
    • Ohishi K., Varnum-Finney B., and Bernstein I.D. Delta-1 enhances marrow and thymus repopulating ability of human CD34(+)CD38(-) cord blood cells. J. Clin. Invest. 110 (2002) 1165-1174
    • (2002) J. Clin. Invest. , vol.110 , pp. 1165-1174
    • Ohishi, K.1    Varnum-Finney, B.2    Bernstein, I.D.3
  • 60
    • 0031930238 scopus 로고    scopus 로고
    • The human homolog of rat Jagged1 expressed by marrow stroma inhibits differentiation of 32D cells through interaction with Notch1
    • Li L., Milner L.A., Deng Y., Iwata M., Banta A., Graf L., et al. The human homolog of rat Jagged1 expressed by marrow stroma inhibits differentiation of 32D cells through interaction with Notch1. Immunity 8 (1998) 43-55
    • (1998) Immunity , vol.8 , pp. 43-55
    • Li, L.1    Milner, L.A.2    Deng, Y.3    Iwata, M.4    Banta, A.5    Graf, L.6
  • 61
    • 35348921682 scopus 로고    scopus 로고
    • Self-renewing osteoprogenitors in bone marrow sinusoids can organize a hematopoietic microenvironment
    • Sacchetti B., Funari A., Michienzi S., Di Cesare S., Piersanti S., Saggio I., et al. Self-renewing osteoprogenitors in bone marrow sinusoids can organize a hematopoietic microenvironment. Cell 131 (2007) 324-336
    • (2007) Cell , vol.131 , pp. 324-336
    • Sacchetti, B.1    Funari, A.2    Michienzi, S.3    Di Cesare, S.4    Piersanti, S.5    Saggio, I.6
  • 62
    • 0035138914 scopus 로고    scopus 로고
    • Activated parathyroid hormone/parathyroid hormone-related protein receptor in osteoblastic cells differentially affects cortical and trabecular bone
    • Calvi L.M., Sims N.A., Hunzelman J.L., Knight M.C., Giovannetti A., Saxton J.M., et al. Activated parathyroid hormone/parathyroid hormone-related protein receptor in osteoblastic cells differentially affects cortical and trabecular bone. J. Clin. Invest. 107 (2001) 277-286
    • (2001) J. Clin. Invest. , vol.107 , pp. 277-286
    • Calvi, L.M.1    Sims, N.A.2    Hunzelman, J.L.3    Knight, M.C.4    Giovannetti, A.5    Saxton, J.M.6
  • 63
    • 0038165507 scopus 로고    scopus 로고
    • Gene expression profiles and transcription factors involved in parathyroid hormone signaling in osteoblasts revealed by microarray and bioinformatics
    • Qin L., Qiu P., Wang L., Li X., Swarthout J.T., Soteropoulos P., et al. Gene expression profiles and transcription factors involved in parathyroid hormone signaling in osteoblasts revealed by microarray and bioinformatics. J. Biol. Chem. 278 (2003) 19723-19731
    • (2003) J. Biol. Chem. , vol.278 , pp. 19723-19731
    • Qin, L.1    Qiu, P.2    Wang, L.3    Li, X.4    Swarthout, J.T.5    Soteropoulos, P.6
  • 65
  • 66
    • 15244346226 scopus 로고    scopus 로고
    • Jagged1-dependent Notch signaling is dispensable for hematopoietic stem cell self-renewal and differentiation
    • Mancini S.J., Mantei N., Dumortier A., Suter U., MacDonald H.R., and Radtke F. Jagged1-dependent Notch signaling is dispensable for hematopoietic stem cell self-renewal and differentiation. Blood 105 (2005) 2340-2342
    • (2005) Blood , vol.105 , pp. 2340-2342
    • Mancini, S.J.1    Mantei, N.2    Dumortier, A.3    Suter, U.4    MacDonald, H.R.5    Radtke, F.6
  • 67
    • 41449089457 scopus 로고    scopus 로고
    • Canonical notch signaling is dispensable for the maintenance of adult hematopoietic stem cells
    • Maillard I., Koch U., Dumortier A., Shestova O., Xu L., Sai H., et al. Canonical notch signaling is dispensable for the maintenance of adult hematopoietic stem cells. Cell Stem Cell 2 (2008) 356-366
    • (2008) Cell Stem Cell , vol.2 , pp. 356-366
    • Maillard, I.1    Koch, U.2    Dumortier, A.3    Shestova, O.4    Xu, L.5    Sai, H.6
  • 68
    • 58149388329 scopus 로고    scopus 로고
    • Defective Notch activation in microenvironment leads to myeloproliferative disease
    • Kim Y.W., Koo B.K., Jeong H.W., Yoon M.J., Song R., Shin J., et al. Defective Notch activation in microenvironment leads to myeloproliferative disease. Blood 112 (2008) 4628-4638
    • (2008) Blood , vol.112 , pp. 4628-4638
    • Kim, Y.W.1    Koo, B.K.2    Jeong, H.W.3    Yoon, M.J.4    Song, R.5    Shin, J.6
  • 69
    • 3242669145 scopus 로고    scopus 로고
    • Tie2/angiopoietin-1 signaling regulates hematopoietic stem cell quiescence in the bone marrow niche
    • Arai F., Hirao A., Ohmura M., Sato H., Matsuoka S., Takubo K., et al. Tie2/angiopoietin-1 signaling regulates hematopoietic stem cell quiescence in the bone marrow niche. Cell 118 (2004) 149-161
    • (2004) Cell , vol.118 , pp. 149-161
    • Arai, F.1    Hirao, A.2    Ohmura, M.3    Sato, H.4    Matsuoka, S.5    Takubo, K.6
  • 70
    • 21344474104 scopus 로고    scopus 로고
    • Osteopontin, a key component of the hematopoietic stem cell niche and regulator of primitive hematopoietic progenitor cells
    • Nilsson S.K., Johnston H.M., Whitty G.A., Williams B., Webb R.J., Denhardt D.T., et al. Osteopontin, a key component of the hematopoietic stem cell niche and regulator of primitive hematopoietic progenitor cells. Blood 106 (2005) 1232-1239
    • (2005) Blood , vol.106 , pp. 1232-1239
    • Nilsson, S.K.1    Johnston, H.M.2    Whitty, G.A.3    Williams, B.4    Webb, R.J.5    Denhardt, D.T.6
  • 71
    • 21244472780 scopus 로고    scopus 로고
    • Osteopontin is a hematopoietic stem cell niche component that negatively regulates stem cell pool size
    • Stier S., Ko Y., Forkert R., Lutz C., Neuhaus T., Grunewald E., et al. Osteopontin is a hematopoietic stem cell niche component that negatively regulates stem cell pool size. J. Exp. Med. 201 (2005) 1781-1791
    • (2005) J. Exp. Med. , vol.201 , pp. 1781-1791
    • Stier, S.1    Ko, Y.2    Forkert, R.3    Lutz, C.4    Neuhaus, T.5    Grunewald, E.6
  • 72
    • 34347400986 scopus 로고    scopus 로고
    • Annexin II expressed by osteoblasts and endothelial cells regulates stem cell adhesion, homing, and engraftment following transplantation
    • Jung Y., Wang J., Song J., Shiozawa Y., Havens A., Wang Z., et al. Annexin II expressed by osteoblasts and endothelial cells regulates stem cell adhesion, homing, and engraftment following transplantation. Blood 110 (2007) 82-90
    • (2007) Blood , vol.110 , pp. 82-90
    • Jung, Y.1    Wang, J.2    Song, J.3    Shiozawa, Y.4    Havens, A.5    Wang, Z.6
  • 73
    • 0037737728 scopus 로고    scopus 로고
    • A role for Wnt signalling in self-renewal of haematopoietic stem cells
    • Reya T., Duncan A.W., Ailles L., Domen J., Scherer D.C., Willert K., et al. A role for Wnt signalling in self-renewal of haematopoietic stem cells. Nature 423 (2003) 409-414
    • (2003) Nature , vol.423 , pp. 409-414
    • Reya, T.1    Duncan, A.W.2    Ailles, L.3    Domen, J.4    Scherer, D.C.5    Willert, K.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.