Corresponding functional dynamics across the Hsp90 chaperone family: Insights from a multiscale analysis of MD simulations

PLoS Computational Biology

Volumn 8, Issue 3, 2012, Pages

  Morra, Giulia ^a   Potestio, Raffaello ^b,c   Micheletti, Cristian ^b   Colombo, Giorgio ^a  

^a CNR   (Italy)

^b IOM CNR LABORATORIO TASC   (Italy)

^c MAX PLANCK INSTITUTE FOR POLYMER RESEARCH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

DYNAMICS; ESCHERICHIA COLI; LIGANDS; MAMMALS; PROTEINS;

ATOMISTIC SIMULATIONS; CRYSTALS STRUCTURES; FULL-LENGTH PROTEINS; LARGE SCALE MOTION; MD SIMULATION; MOLECULE LIGANDS; MULTI SCALE ANALYSIS; PROTEIN DOMAINS; PROTEIN MODIFICATIONS; SMALL MOLECULES;

MOLECULAR BIOLOGY;

ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; CHAPERONE; ESCHERICHIA COLI PROTEIN HTPG; GLUCOSE REGULATED PROTEIN 94; HEAT SHOCK PROTEIN 90; UNCLASSIFIED DRUG;

ALPHA HELIX; AMINO TERMINAL SEQUENCE; ARTICLE; BINDING SITE; CARBOXY TERMINAL SEQUENCE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CRYSTAL STRUCTURE; ESCHERICHIA COLI; HINGE REGION; LIGAND BINDING; MAMMAL; MATHEMATICAL ANALYSIS; MIDDLE DOMAIN; MOLECULAR DYNAMICS; MULTISCALE ANALYSIS; NONHUMAN; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN HYDROLYSIS; PROTEIN MODIFICATION; STRUCTURE ANALYSIS; YEAST;

MAMMALIA;

EID: 84861005184     PISSN: 1553734X     EISSN: 15537358     Source Type: Journal    
DOI: 10.1371/journal.pcbi.1002433     Document Type: Article

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