Intrinsic inhibition of the Hsp90 ATPase activity

Journal of Biological Chemistry

Volumn 281, Issue 16, 2006, Pages 11301-11311

  Richter, Klaus ^a   Moser, Sandra ^a   Hagn, Franz ^a   Friedrich, Rainer ^a   Hainzl, Otmar ^a   Heller, Markus ^a,c   Schlee, Sandra ^b   Kessler, Horst ^a   Reinstein, Jochen ^b   Buchner, Johannes ^a  

^a TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^b MAX PLANCK INSTITUTE FOR MEDICAL RESEARCH   (Germany)

^c UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINETRIPHOSPHATE; AMINO ACIDS; CONFORMATIONS; DIMERIZATION; ENZYME INHIBITION; HYDROLYSIS; SIGNALING; YEAST;

ATPASE REACTION CYCLE; KINETIC INHIBITOR; N-TERMINAL DIMERIZATION; SIGNAL TRANSDUCTION;

PROTEINS;

ADENOSINE TRIPHOSPHATASE; AMINO ACID; HEAT SHOCK PROTEIN 90; HETERODIMER;

AMINO TERMINAL SEQUENCE; ARTICLE; CONTROLLED STUDY; CRYSTAL STRUCTURE; DIMERIZATION; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME INHIBITION; ENZYME KINETICS; ENZYME MECHANISM; ENZYME METABOLISM; NONHUMAN; PRIORITY JOURNAL; PROTEIN STABILITY;

ADENOSINE TRIPHOSPHATASES; ADENOSINE TRIPHOSPHATE; AMINO ACID SEQUENCE; CIRCULAR DICHROISM; CLONING, MOLECULAR; CRYSTALLOGRAPHY, X-RAY; DIFFUSION; DIMERIZATION; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; GENE DELETION; HSP90 HEAT-SHOCK PROTEINS; HYDROLYSIS; KINETICS; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; MOLECULAR CONFORMATION; MOLECULAR SEQUENCE DATA; MUTATION; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN STRUCTURE, QUATERNARY; PROTEIN STRUCTURE, TERTIARY; PROTEINS; SACCHAROMYCES CEREVISIAE; SIGNAL TRANSDUCTION; SUBSTRATE SPECIFICITY; TIME FACTORS; UREA;

EID: 33744956564     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M510142200     Document Type: Article

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