The creation of transgenic pigs expressing human proteins using BAC-derived, full-length genes and intracytoplasmic sperm injection-mediated gene transfer

Transgenic Research

Volumn 21, Issue 3, 2012, Pages 605-618

  Watanabe, Masahito ^a,b   Kurome, Mayuko ^c   Matsunari, Hitomi ^b   Nakano, Kazuaki ^b   Umeyema, Kazuhiro ^b   Shiota, Akira ^d   Nakauchi, Hiromitsu ^a,e   Nagashima, Hiroshi ^a,b  

^a JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^b MEIJI UNIVERSITY   (Japan)

^c UNIVERSITY OF MUNICH   (Germany)

^d PhoenixBio   (Japan)

^e THE UNIVERSITY OF TOKYO   (Japan)

Author keywords

Bacterial artificial chromosome; Human protein production; ICSI mediated gene transfer; Transgenic pig

Indexed keywords

ALB PROTEIN, HUMAN; COLLAGEN TYPE 1; SERUM ALBUMIN;

ANIMAL; ARTICLE; BACTERIAL ARTIFICIAL CHROMOSOME; CYTOLOGY; EMBRYO CULTURE; FLUORESCENCE IN SITU HYBRIDIZATION; GENE TRANSFER; GENETICS; HUMAN; INTRACYTOPLASMIC SPERM INJECTION; METABOLISM; METHODOLOGY; OOCYTE; REAL TIME POLYMERASE CHAIN REACTION; SWINE; TRANSGENE; TRANSGENIC ANIMAL;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; CHROMOSOMES, ARTIFICIAL, BACTERIAL; COLLAGEN TYPE I; EMBRYO CULTURE TECHNIQUES; GENE TRANSFER TECHNIQUES; HUMANS; IN SITU HYBRIDIZATION, FLUORESCENCE; OOCYTES; REAL-TIME POLYMERASE CHAIN REACTION; SERUM ALBUMIN; SPERM INJECTIONS, INTRACYTOPLASMIC; SWINE; TRANSGENES;

ANIMALIA; BACTERIA (MICROORGANISMS); SUIDAE; SUS;

EID: 84860889151     PISSN: 09628819     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11248-011-9561-3     Document Type: Article

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