DNA dose and sequence dependence in sperm-mediated gene transfer

Molecular Reproduction and Development

Volumn 56, Issue 2 SUPPL., 2000, Pages 301-305

  Sciamanna, Ilaria ^a   Piccoli, Simona ^a   Barberi, Laura ^a   Zaccagnini, Germana ^a   Magnano, Anna Rosa ^a,b   Giordano, Roberto ^a   Campedelli, Paolo ^c   Hodgson, Clague ^d   Lorenzini, Rodolfo ^c   Spadafora, Corrado ^a  

^a CNR   (Italy)

^b UNIVERSITY OF SIENA   (Italy)

^c ISTITUTO SUPERIORE DI SANITÀ   (Italy)

^d NATURE TECHNOLOGY CORPORATION   (United States)

Author keywords

Fertilization; Recombinant DNA; Spermatozoa; Transgenic animals

Indexed keywords

RECOMBINANT DNA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; CHROMOSOME MOSAICISM; CONFERENCE PAPER; CONTROLLED STUDY; DNA SEQUENCE; DNA STRUCTURE; EMBRYO; EMBRYO DEVELOPMENT; EPIDIDYMIS; FERTILIZATION; GENE TRANSFER; GENETIC TRANSFORMATION; MOUSE; NEWBORN; NONHUMAN; PRIORITY JOURNAL; RETROPOSON; TRANSGENIC ANIMAL;

ANIMALIA;

EID: 0034065779     PISSN: 1040452X     EISSN: None     Source Type: Journal    
DOI: 10.1002/(sici)1098-2795(200006)56:2+<301::aid-mrd20>3.0.co;2-b     Document Type: Conference Paper

References (10)

1. Hodgson CP, Chakraborty AK, Zink MA, Xu G. 1996. Construction, transmission and expression of synthetic VL30 vectors. In: Hodgson CP, editor. Retro-vectors for human gene therapy. New York: Chapman and Hall. p 103-128.
2. Lavitrano M, Camaioni A, Fazio V, Dolci S, Farace MG, Spadafora C. 1989. Sperm cells as vectors for introducing foreign DNA into eggs: genetic transformation of mice. Cell 57:717-723.
3. Maione B, Pittoggi C, Achene L, Lorenzini R, Spadafora C. 1997. Activation of endogenous nucleases in mature sperm cells upon interaction with exogenous DNA. DNA Cell Biol 16:1087-1097.
4. Maione B, Lavitrano M, Spadafora C, Kiessling A. 1998. Sperm-mediated gene transfer in mice. Mol Reprod Dev 50:406-409.
5. Perry AC, Wakayama T, Kishikawa H, Kasai T, Okabe M, Toyoda Y, Yanagimachi R. 1999. Mammalian transgenesis by intracytoplasmic sperm injection. Science 284:1180-1183.
6. Shemesh M, Gurevich M, Harel-Marcowitz E, Benvenisti L, Shore LS, Stram Y. 2000. Gene integration into bovine sperm genome and its expression in transgenic offspring. Mol Reprod Dev 56: 306-315.
7. Spadafora C. 1998. Sperm cells and foreign DNA: a controversial relation. BioEssays 20:955-964.
8. Sperandio S, Lulli V, Bacci ML, Forni M, Maione B, Spadafora C, Lavitrano M. 1996. Sperm-mediated DNA transfer in bovine and swine species. Animal Biotechnol 7:59-77.
9. Zaccagnini G, Maione B, Lorenzini R, Spadafora C. 1998. Increased production of mouse embryos in in vitro fertilization by preincubating sperm cells with the nuclease inhibitor aurintricarboxylic acid (ATA). Biol Reprod 59:1549-1553.
10. Zani M, Lavitrano M, French D, Lulli V, Maione B, Sperandio S, Spadafora C. 1995. The mechanism of binding of exogenous DNA to sperm cells: factors controlling the DNA uptake. Exp Cell Res 217:57-64.