Dominant-negative mutant hepatocyte nuclear factor 1α induces diabetes in transgenic-cloned pigs

Transgenic Research

Volumn 18, Issue 5, 2009, Pages 697-706

  Umeyama, Kazuhiro ^a   Watanabe, Masahito ^a   Saito, Hitoshi ^b   Kurome, Mayuko ^b   Tohi, Sadaaki ^b   Matsunari, Hitomi ^b   Miki, Keizaburo ^a   Nagashima, Hiroshi ^b  

^a BIOS Research Laboratory Inc   (Japan)

^b MEIJI UNIVERSITY   (Japan)

Author keywords

Diabetic model; Dominant negative; HNF 1 P291fsinsC; Intracytoplasmic sperm injection; Somatic cell nuclear transfer; Transgenic cloned pig

Indexed keywords

HEPATOCYTE NUCLEAR FACTOR 1ALPHA;

ANIMAL; ARTICLE; CLONING; DIABETES MELLITUS; DISEASE MODEL; GENETICS; GLUCOSE BLOOD LEVEL; HUMAN; METABOLISM; MUTATION; SWINE; TRANSGENIC ANIMAL;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; BLOOD GLUCOSE; CLONING, ORGANISM; DIABETES MELLITUS; DISEASE MODELS, ANIMAL; HEPATOCYTE NUCLEAR FACTOR 1-ALPHA; HUMANS; MUTATION; SWINE;

SUIDAE;

EID: 70349981719     PISSN: 09628819     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11248-009-9262-3     Document Type: Article

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