메뉴 건너뛰기




Volumn 23, Issue 6, 2012, Pages 646-655

Capsaicin represses transcriptional activity of β-catenin in human colorectal cancer cells

Author keywords

catenin; Capsaicin; Colorectal cancer; TCF 4

Indexed keywords

BETA CATENIN; CAPSAICIN; LUCIFERASE; T CELL FACTOR PROTEIN;

EID: 84860887229     PISSN: 09552863     EISSN: 18734847     Source Type: Journal    
DOI: 10.1016/j.jnutbio.2011.03.009     Document Type: Article
Times cited : (81)

References (55)
  • 4
    • 0037021625 scopus 로고    scopus 로고
    • Antioxidant and antiproliferative activities of common vegetables
    • Chu Y.F., Sun J., Wu X., Liu R.H. Antioxidant and antiproliferative activities of common vegetables. J Agric Food Chem 2002, 50:6910-6916.
    • (2002) J Agric Food Chem , vol.50 , pp. 6910-6916
    • Chu, Y.F.1    Sun, J.2    Wu, X.3    Liu, R.H.4
  • 5
    • 22444441315 scopus 로고    scopus 로고
    • US Department of Agriculture Economic Research Service, Washington, DC, Publication VGS-313
    • Lucier G., Jerardo A. Vegetables and melons outlook 2007, US Department of Agriculture Economic Research Service, Washington, DC, Publication VGS-313.
    • (2007) Vegetables and melons outlook
    • Lucier, G.1    Jerardo, A.2
  • 6
    • 0035513592 scopus 로고    scopus 로고
    • Chemoprevention of azoxymethane-induced rat colon carcinogenesis by dietary capsaicin and rotenone
    • Yoshitani S.I., Tanaka T., Kohno H., Takashima S. Chemoprevention of azoxymethane-induced rat colon carcinogenesis by dietary capsaicin and rotenone. Int J Oncol 2001, 19:929-939.
    • (2001) Int J Oncol , vol.19 , pp. 929-939
    • Yoshitani, S.I.1    Tanaka, T.2    Kohno, H.3    Takashima, S.4
  • 7
    • 34247898927 scopus 로고    scopus 로고
    • Involvement of AMPK signaling cascade in capsaicin-induced apoptosis of HT-29 colon cancer cells
    • Kim Y.M., Hwang J.T., Kwak D.W., Lee Y.K., Park O.J. Involvement of AMPK signaling cascade in capsaicin-induced apoptosis of HT-29 colon cancer cells. Ann N Y Acad Sci 2007, 1095:496-503.
    • (2007) Ann N Y Acad Sci , vol.1095 , pp. 496-503
    • Kim, Y.M.1    Hwang, J.T.2    Kwak, D.W.3    Lee, Y.K.4    Park, O.J.5
  • 8
    • 33749533243 scopus 로고    scopus 로고
    • Capsaicin induced cell cycle arrest and apoptosis in human esophagus epidermoid carcinoma CE 81T/VGH cells through the elevation of intracellular reactive oxygen species and Ca2+ productions and caspase-3 activation
    • Wu C.C., Lin J.P., Yang J.S., Chou S.T., Chen S.C., Lin Y.T., et al. Capsaicin induced cell cycle arrest and apoptosis in human esophagus epidermoid carcinoma CE 81T/VGH cells through the elevation of intracellular reactive oxygen species and Ca2+ productions and caspase-3 activation. Mutat Res 2006, 601:71-82.
    • (2006) Mutat Res , vol.601 , pp. 71-82
    • Wu, C.C.1    Lin, J.P.2    Yang, J.S.3    Chou, S.T.4    Chen, S.C.5    Lin, Y.T.6
  • 9
    • 0842304283 scopus 로고    scopus 로고
    • Induction of apoptosis in leukemic cells by homovanillic acid derivative, capsaicin, through oxidative stress: implication of phosphorylation of p53 at Ser-15 residue by reactive oxygen species
    • Ito K., Nakazato T., Yamato K., Miyakawa Y., Yamada T., Hozumi N., et al. Induction of apoptosis in leukemic cells by homovanillic acid derivative, capsaicin, through oxidative stress: implication of phosphorylation of p53 at Ser-15 residue by reactive oxygen species. Cancer Res 2004, 64:1071-1078.
    • (2004) Cancer Res , vol.64 , pp. 1071-1078
    • Ito, K.1    Nakazato, T.2    Yamato, K.3    Miyakawa, Y.4    Yamada, T.5    Hozumi, N.6
  • 10
    • 33645533257 scopus 로고    scopus 로고
    • Capsaicin, a component of red peppers, inhibits the growth of androgen-independent, p53 mutant prostate cancer cells
    • Mori A., Lehmann S., O'Kelly J., Kumagai T., Desmond J.C., Pervan M., et al. Capsaicin, a component of red peppers, inhibits the growth of androgen-independent, p53 mutant prostate cancer cells. Cancer Res 2006, 66:3222-3229.
    • (2006) Cancer Res , vol.66 , pp. 3222-3229
    • Mori, A.1    Lehmann, S.2    O'Kelly, J.3    Kumagai, T.4    Desmond, J.C.5    Pervan, M.6
  • 11
    • 77956314277 scopus 로고    scopus 로고
    • Capsaicin displays anti-proliferative activity against human small cell lung cancer in cell culture and nude mice models via the E2F pathway
    • Brown K.C., Witte T.R., Hardman W.E., Luo H., Chen Y.C., Carpenter A.B., et al. Capsaicin displays anti-proliferative activity against human small cell lung cancer in cell culture and nude mice models via the E2F pathway. PLoS One 2010, 5:e10243.
    • (2010) PLoS One , vol.5
    • Brown, K.C.1    Witte, T.R.2    Hardman, W.E.3    Luo, H.4    Chen, Y.C.5    Carpenter, A.B.6
  • 12
    • 74449084136 scopus 로고    scopus 로고
    • Capsaicin causes cell-cycle arrest and apoptosis in ER-positive and -negative breast cancer cells by modulating the EGFR/HER-2 pathway
    • Thoennissen N.H., O'Kelly J., Lu D., Iwanski G.B., La D.T., Abbassi S., et al. Capsaicin causes cell-cycle arrest and apoptosis in ER-positive and -negative breast cancer cells by modulating the EGFR/HER-2 pathway. Oncogene 2010, 29:285-296.
    • (2010) Oncogene , vol.29 , pp. 285-296
    • Thoennissen, N.H.1    O'Kelly, J.2    Lu, D.3    Iwanski, G.B.4    La, D.T.5    Abbassi, S.6
  • 13
    • 56349151331 scopus 로고    scopus 로고
    • In vitro and in vivo induction of apoptosis by capsaicin in pancreatic cancer cells is mediated through ROS generation and mitochondrial death pathway
    • Zhang R., Humphreys I., Sahu R.P., Shi Y., Srivastava S.K. In vitro and in vivo induction of apoptosis by capsaicin in pancreatic cancer cells is mediated through ROS generation and mitochondrial death pathway. Apoptosis 2008, 13:1465-1478.
    • (2008) Apoptosis , vol.13 , pp. 1465-1478
    • Zhang, R.1    Humphreys, I.2    Sahu, R.P.3    Shi, Y.4    Srivastava, S.K.5
  • 14
    • 77956271267 scopus 로고    scopus 로고
    • Cocarcinogenic effect of capsaicin involves activation of EGFR signaling but not TRPV1
    • Hwang M.K., Bode A.M., Byun S., Song N.R., Lee H.J., Lee K.W., et al. Cocarcinogenic effect of capsaicin involves activation of EGFR signaling but not TRPV1. Cancer Res 2010, 70:6859-6869.
    • (2010) Cancer Res , vol.70 , pp. 6859-6869
    • Hwang, M.K.1    Bode, A.M.2    Byun, S.3    Song, N.R.4    Lee, H.J.5    Lee, K.W.6
  • 15
    • 0023031060 scopus 로고
    • Tumour-promoting effect of chilli extract in BALB/c mice
    • Agrawal R.C., Wiessler M., Hecker E., Bhide S.V. Tumour-promoting effect of chilli extract in BALB/c mice. Int J Cancer 1986, 38:689-695.
    • (1986) Int J Cancer , vol.38 , pp. 689-695
    • Agrawal, R.C.1    Wiessler, M.2    Hecker, E.3    Bhide, S.V.4
  • 16
    • 77950896712 scopus 로고    scopus 로고
    • NSAID-activated gene-1 as a molecular target for capsaicin-induced apoptosis through a novel molecular mechanism involving GSK3{beta}, C/EBP{beta}, and ATF3
    • Lee S.H., Krisanapun C., Baek S.J. NSAID-activated gene-1 as a molecular target for capsaicin-induced apoptosis through a novel molecular mechanism involving GSK3{beta}, C/EBP{beta}, and ATF3. Carcinogenesis 2010, 31:719-728.
    • (2010) Carcinogenesis , vol.31 , pp. 719-728
    • Lee, S.H.1    Krisanapun, C.2    Baek, S.J.3
  • 17
    • 70349570949 scopus 로고    scopus 로고
    • Capsaicin induces apoptosis by generating reactive oxygen species and disrupting mitochondrial transmembrane potential in human colon cancer cell lines
    • Yang K.M., Pyo J.O., Kim G.Y., Yu R., Han I.S., Ju S.A., et al. Capsaicin induces apoptosis by generating reactive oxygen species and disrupting mitochondrial transmembrane potential in human colon cancer cell lines. Cell Mol Biol Lett 2009, 14:497-510.
    • (2009) Cell Mol Biol Lett , vol.14 , pp. 497-510
    • Yang, K.M.1    Pyo, J.O.2    Kim, G.Y.3    Yu, R.4    Han, I.S.5    Ju, S.A.6
  • 18
    • 71949091112 scopus 로고    scopus 로고
    • Apoptosis induced by capsaicin and resveratrol in colon carcinoma cells requires nitric oxide production and caspase activation
    • Kim M.Y., Trudel L.J., Wogan G.N. Apoptosis induced by capsaicin and resveratrol in colon carcinoma cells requires nitric oxide production and caspase activation. Anticancer Res 2009, 29:3733-3740.
    • (2009) Anticancer Res , vol.29 , pp. 3733-3740
    • Kim, M.Y.1    Trudel, L.J.2    Wogan, G.N.3
  • 19
    • 4644295000 scopus 로고    scopus 로고
    • Capsaicin, a spicy component of hot pepper, induces apoptosis by activation of the peroxisome proliferator-activated receptor gamma in HT-29 human colon cancer cells
    • Kim C.S., Park W.H., Park J.Y., Kang J.H., Kim M.O., Kawada T., et al. Capsaicin, a spicy component of hot pepper, induces apoptosis by activation of the peroxisome proliferator-activated receptor gamma in HT-29 human colon cancer cells. J Med Food 2004, 7:267-273.
    • (2004) J Med Food , vol.7 , pp. 267-273
    • Kim, C.S.1    Park, W.H.2    Park, J.Y.3    Kang, J.H.4    Kim, M.O.5    Kawada, T.6
  • 21
    • 33947304343 scopus 로고    scopus 로고
    • TRPV6 mediates capsaicin-induced apoptosis in gastric cancer cells - mechanisms behind a possible new ' hot' cancer treatment
    • Chow J., Norng M., Zhang J., Chai J. TRPV6 mediates capsaicin-induced apoptosis in gastric cancer cells - mechanisms behind a possible new ' hot' cancer treatment. Biochim Biophys Acta 2007, 1773:565-576.
    • (2007) Biochim Biophys Acta , vol.1773 , pp. 565-576
    • Chow, J.1    Norng, M.2    Zhang, J.3    Chai, J.4
  • 22
    • 77950373388 scopus 로고    scopus 로고
    • Capsaicin induces apoptosis through ubiquitin-proteasome system dysfunction
    • Maity R., Sharma J., Jana N.R. Capsaicin induces apoptosis through ubiquitin-proteasome system dysfunction. J Cell Biochem 2010, 109:933-942.
    • (2010) J Cell Biochem , vol.109 , pp. 933-942
    • Maity, R.1    Sharma, J.2    Jana, N.R.3
  • 23
    • 0032871895 scopus 로고    scopus 로고
    • APC: the plot thickens
    • Bienz M. APC: the plot thickens. Curr Opin Genet Dev 1999, 9:595-603.
    • (1999) Curr Opin Genet Dev , vol.9 , pp. 595-603
    • Bienz, M.1
  • 24
    • 0033119801 scopus 로고    scopus 로고
    • Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells
    • Tetsu O., McCormick F. Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells. Nature 1999, 398:422-426.
    • (1999) Nature , vol.398 , pp. 422-426
    • Tetsu, O.1    McCormick, F.2
  • 26
    • 0033615352 scopus 로고    scopus 로고
    • PPARdelta is an APC-regulated target of nonsteroidal anti-inflammatory drugs
    • He T.C., Chan T.A., Vogelstein B., Kinzler K.W. PPARdelta is an APC-regulated target of nonsteroidal anti-inflammatory drugs. Cell 1999, 99:335-345.
    • (1999) Cell , vol.99 , pp. 335-345
    • He, T.C.1    Chan, T.A.2    Vogelstein, B.3    Kinzler, K.W.4
  • 27
    • 18644373146 scopus 로고    scopus 로고
    • The beta-catenin/TCF-4 complex imposes a crypt progenitor phenotype on colorectal cancer cells
    • van de Wetering M., Sancho E., Verweij C., de Lau W., Oving I., Hurlstone A., et al. The beta-catenin/TCF-4 complex imposes a crypt progenitor phenotype on colorectal cancer cells. Cell 2002, 111:241-250.
    • (2002) Cell , vol.111 , pp. 241-250
    • van de Wetering, M.1    Sancho, E.2    Verweij, C.3    de Lau, W.4    Oving, I.5    Hurlstone, A.6
  • 28
    • 0037028207 scopus 로고    scopus 로고
    • Beta-catenin-mediated transactivation and cell-cell adhesion pathways are important in curcumin (diferuylmethane)-induced growth arrest and apoptosis in colon cancer cells
    • Jaiswal A.S., Marlow B.P., Gupta N., Narayan S. Beta-catenin-mediated transactivation and cell-cell adhesion pathways are important in curcumin (diferuylmethane)-induced growth arrest and apoptosis in colon cancer cells. Oncogene 2002, 21:8414-8427.
    • (2002) Oncogene , vol.21 , pp. 8414-8427
    • Jaiswal, A.S.1    Marlow, B.P.2    Gupta, N.3    Narayan, S.4
  • 29
    • 34250376883 scopus 로고    scopus 로고
    • Involvement of PPARgamma and E-cadherin/beta-catenin pathway in the antiproliferative effect of conjugated linoleic acid in MCF-7 cells
    • Bocca C., Bozzo F., Francica S., Colombatto S., Miglietta A. Involvement of PPARgamma and E-cadherin/beta-catenin pathway in the antiproliferative effect of conjugated linoleic acid in MCF-7 cells. Int J Cancer 2007, 121:248-256.
    • (2007) Int J Cancer , vol.121 , pp. 248-256
    • Bocca, C.1    Bozzo, F.2    Francica, S.3    Colombatto, S.4    Miglietta, A.5
  • 30
    • 0036384133 scopus 로고    scopus 로고
    • Inhibition of beta-catenin/Tcf activity by white tea, green tea, and epigallocatechin-3-gallate (EGCG): minor contribution of H(2)O(2) at physiologically relevant EGCG concentrations
    • Dashwood W.M., Orner G.A., Dashwood R.H. Inhibition of beta-catenin/Tcf activity by white tea, green tea, and epigallocatechin-3-gallate (EGCG): minor contribution of H(2)O(2) at physiologically relevant EGCG concentrations. Biochem Biophys Res Commun 2002, 296:584-588.
    • (2002) Biochem Biophys Res Commun , vol.296 , pp. 584-588
    • Dashwood, W.M.1    Orner, G.A.2    Dashwood, R.H.3
  • 31
    • 33646197169 scopus 로고    scopus 로고
    • Conjugated linoleic acid stimulates an anti-tumorigenic protein NAG-1 in an isomer specific manner
    • Lee S.H., Yamaguchi K., Kim J.S., Eling T.E., Safe S., Park Y., et al. Conjugated linoleic acid stimulates an anti-tumorigenic protein NAG-1 in an isomer specific manner. Carcinogenesis 2006, 27:972-981.
    • (2006) Carcinogenesis , vol.27 , pp. 972-981
    • Lee, S.H.1    Yamaguchi, K.2    Kim, J.S.3    Eling, T.E.4    Safe, S.5    Park, Y.6
  • 32
    • 40749083585 scopus 로고    scopus 로고
    • Multiple mechanisms are involved in 6-gingerol-induced cell growth arrest and apoptosis in human colorectal cancer cells
    • Lee S.H., Cekanova M., Baek S.J. Multiple mechanisms are involved in 6-gingerol-induced cell growth arrest and apoptosis in human colorectal cancer cells. Molecular Carcinogenesis 2008, 47:197-208.
    • (2008) Molecular Carcinogenesis , vol.47 , pp. 197-208
    • Lee, S.H.1    Cekanova, M.2    Baek, S.J.3
  • 33
    • 77956898560 scopus 로고    scopus 로고
    • Activating transcription factor 2 (ATF2) controls tolfenamic acid-induced ATF3 expression via MAP kinase pathways
    • Lee S.H., Bahn J.H., Whitlock N.C., Baek S.J. Activating transcription factor 2 (ATF2) controls tolfenamic acid-induced ATF3 expression via MAP kinase pathways. Oncogene 2010, 29:5182-5192.
    • (2010) Oncogene , vol.29 , pp. 5182-5192
    • Lee, S.H.1    Bahn, J.H.2    Whitlock, N.C.3    Baek, S.J.4
  • 34
    • 1542347695 scopus 로고    scopus 로고
    • Convergence of Wnt, beta-catenin, and cadherin pathways
    • Nelson W.J., Nusse R. Convergence of Wnt, beta-catenin, and cadherin pathways. Science 2004, 303:1483-1487.
    • (2004) Science , vol.303 , pp. 1483-1487
    • Nelson, W.J.1    Nusse, R.2
  • 36
    • 0030978351 scopus 로고    scopus 로고
    • Beta-Catenin is a target for the ubiquitin-proteasome pathway
    • Aberle H., Bauer A., Stappert J., Kispert A., Kemler R. beta-Catenin is a target for the ubiquitin-proteasome pathway. EMBO J 1997, 16:3797-3804.
    • (1997) EMBO J , vol.16 , pp. 3797-3804
    • Aberle, H.1    Bauer, A.2    Stappert, J.3    Kispert, A.4    Kemler, R.5
  • 37
    • 0037019748 scopus 로고    scopus 로고
    • More than spice: capsaicin in hot chili peppers makes tumor cells commit suicide
    • Surh Y.J. More than spice: capsaicin in hot chili peppers makes tumor cells commit suicide. J Natl Cancer Inst 2002, 94:1263-1265.
    • (2002) J Natl Cancer Inst , vol.94 , pp. 1263-1265
    • Surh, Y.J.1
  • 38
    • 0036199569 scopus 로고    scopus 로고
    • Indomethacin induces differential expression of beta-catenin, gamma-catenin and T-cell factor target genes in human colorectal cancer cells
    • Hawcroft G., D'Amico M., Albanese C., Markham A.F., Pestell R.G., Hull M.A. Indomethacin induces differential expression of beta-catenin, gamma-catenin and T-cell factor target genes in human colorectal cancer cells. Carcinogenesis 2002, 23:107-114.
    • (2002) Carcinogenesis , vol.23 , pp. 107-114
    • Hawcroft, G.1    D'Amico, M.2    Albanese, C.3    Markham, A.F.4    Pestell, R.G.5    Hull, M.A.6
  • 39
    • 77953480176 scopus 로고    scopus 로고
    • PKG inhibits TCF signaling in colon cancer cells by blocking beta-catenin expression and activating FOXO4
    • Kwon I.K., Wang R., Thangaraju M., Shuang H., Liu K., Dashwood R., et al. PKG inhibits TCF signaling in colon cancer cells by blocking beta-catenin expression and activating FOXO4. Oncogene 2010, 29:3423-3434.
    • (2010) Oncogene , vol.29 , pp. 3423-3434
    • Kwon, I.K.1    Wang, R.2    Thangaraju, M.3    Shuang, H.4    Liu, K.5    Dashwood, R.6
  • 40
    • 0035186239 scopus 로고    scopus 로고
    • The expression of E-cadherin and catenins in sporadic colorectal carcinoma
    • El-Bahrawy M.A., Poulsom R., Jeffery R., Talbot I., Alison M.R. The expression of E-cadherin and catenins in sporadic colorectal carcinoma. Hum Pathol 2001, 32:1216-1224.
    • (2001) Hum Pathol , vol.32 , pp. 1216-1224
    • El-Bahrawy, M.A.1    Poulsom, R.2    Jeffery, R.3    Talbot, I.4    Alison, M.R.5
  • 41
    • 0036724349 scopus 로고    scopus 로고
    • The expression of E-cadherin and catenins in colorectal tumours from familial adenomatous polyposis patients
    • El-Bahrawy M.A., Talbot I.C., Poulsom R., Jeffery R., Alison M.R. The expression of E-cadherin and catenins in colorectal tumours from familial adenomatous polyposis patients. J Pathol 2002, 198:69-76.
    • (2002) J Pathol , vol.198 , pp. 69-76
    • El-Bahrawy, M.A.1    Talbot, I.C.2    Poulsom, R.3    Jeffery, R.4    Alison, M.R.5
  • 42
    • 41849104684 scopus 로고    scopus 로고
    • Protective versus promotional effects of white tea and caffeine on PhIP-induced tumorigenesis and beta-catenin expression in the rat
    • Wang R., Dashwood W.M., Lohr C.V., Fischer K.A., Pereira C.B., Louderback M., et al. Protective versus promotional effects of white tea and caffeine on PhIP-induced tumorigenesis and beta-catenin expression in the rat. Carcinogenesis 2008, 29:834-839.
    • (2008) Carcinogenesis , vol.29 , pp. 834-839
    • Wang, R.1    Dashwood, W.M.2    Lohr, C.V.3    Fischer, K.A.4    Pereira, C.B.5    Louderback, M.6
  • 43
    • 0346728740 scopus 로고    scopus 로고
    • Cloning of the rat beta-catenin gene (Ctnnb1) promoter and its functional analysis compared with the Catnb and CTNNB1 promoters
    • Li Q., Dashwood W.M., Zhong X., Al-Fageeh M., Dashwood R.H. Cloning of the rat beta-catenin gene (Ctnnb1) promoter and its functional analysis compared with the Catnb and CTNNB1 promoters. Genomics 2004, 83:231-242.
    • (2004) Genomics , vol.83 , pp. 231-242
    • Li, Q.1    Dashwood, W.M.2    Zhong, X.3    Al-Fageeh, M.4    Dashwood, R.H.5
  • 44
    • 0030949463 scopus 로고    scopus 로고
    • Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC
    • Morin P.J., Sparks A.B., Korinek V., Barker N., Clevers H., Vogelstein B., et al. Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC. Science 1997, 275:1787-1790.
    • (1997) Science , vol.275 , pp. 1787-1790
    • Morin, P.J.1    Sparks, A.B.2    Korinek, V.3    Barker, N.4    Clevers, H.5    Vogelstein, B.6
  • 45
    • 4143065010 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gamma activation can regulate beta-catenin levels via a proteasome-mediated and adenomatous polyposis coli-independent pathway
    • Sharma C., Pradeep A., Wong L., Rana A., Rana B. Peroxisome proliferator-activated receptor gamma activation can regulate beta-catenin levels via a proteasome-mediated and adenomatous polyposis coli-independent pathway. J Biol Chem 2004, 279:35583-35594.
    • (2004) J Biol Chem , vol.279 , pp. 35583-35594
    • Sharma, C.1    Pradeep, A.2    Wong, L.3    Rana, A.4    Rana, B.5
  • 46
    • 0043032524 scopus 로고    scopus 로고
    • Adenomatous polyposis coli (APC)-independent regulation of beta-catenin degradation via a retinoid × receptor-mediated pathway
    • Xiao J.H., Ghosn C., Hinchman C., Forbes C., Wang J., Snider N., et al. Adenomatous polyposis coli (APC)-independent regulation of beta-catenin degradation via a retinoid × receptor-mediated pathway. J Biol Chem 2003, 278:29954-29962.
    • (2003) J Biol Chem , vol.278 , pp. 29954-29962
    • Xiao, J.H.1    Ghosn, C.2    Hinchman, C.3    Forbes, C.4    Wang, J.5    Snider, N.6
  • 47
    • 2442712631 scopus 로고    scopus 로고
    • Identification of Tcf-4 as a transcriptional target of p53 signalling
    • Rother K., Johne C., Spiesbach K., Haugwitz U., Tschop K., Wasner M., et al. Identification of Tcf-4 as a transcriptional target of p53 signalling. Oncogene 2004, 23:3376-3384.
    • (2004) Oncogene , vol.23 , pp. 3376-3384
    • Rother, K.1    Johne, C.2    Spiesbach, K.3    Haugwitz, U.4    Tschop, K.5    Wasner, M.6
  • 48
    • 0032521433 scopus 로고    scopus 로고
    • Mutational analysis of the APC/beta-catenin/Tcf pathway in colorectal cancer
    • Sparks A.B., Morin P.J., Vogelstein B., Kinzler K.W. Mutational analysis of the APC/beta-catenin/Tcf pathway in colorectal cancer. Cancer Res 1998, 58:1130-1134.
    • (1998) Cancer Res , vol.58 , pp. 1130-1134
    • Sparks, A.B.1    Morin, P.J.2    Vogelstein, B.3    Kinzler, K.W.4
  • 49
    • 0037155691 scopus 로고    scopus 로고
    • Control of beta-catenin phosphorylation/degradation by a dual-kinase mechanism
    • Liu C., Li Y., Semenov M., Han C., Baeg G.H., Tan Y., et al. Control of beta-catenin phosphorylation/degradation by a dual-kinase mechanism. Cell 2002, 108:837-847.
    • (2002) Cell , vol.108 , pp. 837-847
    • Liu, C.1    Li, Y.2    Semenov, M.3    Han, C.4    Baeg, G.H.5    Tan, Y.6
  • 50
    • 0037069939 scopus 로고    scopus 로고
    • Curcumin-induced suppression of cell proliferation correlates with down-regulation of cyclin D1 expression and CDK4-mediated retinoblastoma protein phosphorylation
    • Mukhopadhyay A., Banerjee S., Stafford L.J., Xia C., Liu M., Aggarwal B.B. Curcumin-induced suppression of cell proliferation correlates with down-regulation of cyclin D1 expression and CDK4-mediated retinoblastoma protein phosphorylation. Oncogene 2002, 21:8852-8861.
    • (2002) Oncogene , vol.21 , pp. 8852-8861
    • Mukhopadhyay, A.1    Banerjee, S.2    Stafford, L.J.3    Xia, C.4    Liu, M.5    Aggarwal, B.B.6
  • 51
    • 0033618250 scopus 로고    scopus 로고
    • Retinoic acid promotes ubiquitination and proteolysis of cyclin D1 during induced tumor cell differentiation
    • Spinella M.J., Freemantle S.J., Sekula D., Chang J.H., Christie A.J., Dmitrovsky E. Retinoic acid promotes ubiquitination and proteolysis of cyclin D1 during induced tumor cell differentiation. J Biol Chem 1999, 274:22013-22018.
    • (1999) J Biol Chem , vol.274 , pp. 22013-22018
    • Spinella, M.J.1    Freemantle, S.J.2    Sekula, D.3    Chang, J.H.4    Christie, A.J.5    Dmitrovsky, E.6
  • 52
    • 15744368845 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gamma-independent ablation of cyclin D1 by thiazolidinediones and their derivatives in breast cancer cells
    • Huang J.W., Shiau C.W., Yang Y.T., Kulp S.K., Chen K.F., Brueggemeier R.W., et al. Peroxisome proliferator-activated receptor gamma-independent ablation of cyclin D1 by thiazolidinediones and their derivatives in breast cancer cells. Mol Pharmacol 2005, 67:1342-1348.
    • (2005) Mol Pharmacol , vol.67 , pp. 1342-1348
    • Huang, J.W.1    Shiau, C.W.2    Yang, Y.T.3    Kulp, S.K.4    Chen, K.F.5    Brueggemeier, R.W.6
  • 53
    • 69449089475 scopus 로고    scopus 로고
    • Triggering of transient receptor potential vanilloid type 1 (TRPV1) by capsaicin induces Fas/CD95-mediated apoptosis of urothelial cancer cells in an A™-dependent manner
    • Amantini C., Ballarini P., Caprodossi S., Nabissi M., Morelli M.B., Lucciarini R., et al. Triggering of transient receptor potential vanilloid type 1 (TRPV1) by capsaicin induces Fas/CD95-mediated apoptosis of urothelial cancer cells in an A™-dependent manner. Carcinogenesis 2009, 30:1320-1329.
    • (2009) Carcinogenesis , vol.30 , pp. 1320-1329
    • Amantini, C.1    Ballarini, P.2    Caprodossi, S.3    Nabissi, M.4    Morelli, M.B.5    Lucciarini, R.6
  • 54
    • 0037374018 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gamma agonists induce proteasome-dependent degradation of cyclin D1 and estrogen receptor alpha in MCF-7 breast cancer cells
    • Qin C., Burghardt R., Smith R., Wormke M., Stewart J., Safe S. Peroxisome proliferator-activated receptor gamma agonists induce proteasome-dependent degradation of cyclin D1 and estrogen receptor alpha in MCF-7 breast cancer cells. Cancer Res 2003, 63:958-964.
    • (2003) Cancer Res , vol.63 , pp. 958-964
    • Qin, C.1    Burghardt, R.2    Smith, R.3    Wormke, M.4    Stewart, J.5    Safe, S.6
  • 55
    • 33846281508 scopus 로고    scopus 로고
    • Vanilloid receptor agonists and antagonists are mitochondrial inhibitors: how vanilloids cause non-vanilloid receptor mediated cell death
    • Athanasiou A., Smith P.A., Vakilpour S., Kumaran N.M., Turner A.E., Bagiokou D., et al. Vanilloid receptor agonists and antagonists are mitochondrial inhibitors: how vanilloids cause non-vanilloid receptor mediated cell death. Biochem Biophys Res Commun 2007, 354:50-55.
    • (2007) Biochem Biophys Res Commun , vol.354 , pp. 50-55
    • Athanasiou, A.1    Smith, P.A.2    Vakilpour, S.3    Kumaran, N.M.4    Turner, A.E.5    Bagiokou, D.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.