Toll-like receptor activation of human cells by synthetic triacylated lipid A-like molecules

Journal of Biological Chemistry

Volumn 287, Issue 20, 2012, Pages 16121-16131

  Dunn Siegrist, Irène ^a   Tissier̀es, Pierre ^a   Drifte, Geneviève ^a   Bauer, Jacques ^b   Moutel, Stéphane ^b   Pugin, Jeŕôme ^a  

^a UNIVERSITY OF GENEVA   (Switzerland)

^b OM PHARMA   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

GRAM-NEGATIVE BACTERIA; HUMAN CELLS; IMMUNE RESPONSE; IMMUNOMODULATORY AGENTS; LIPID A; LIPOPEPTIDES; MAMMALIAN HOSTS; RECEPTOR COMPLEX; TOLL-LIKE RECEPTORS;

ANTIGEN-ANTIBODY REACTIONS; BACTERIA; MAMMALS;

MOLECULES;

GAMMA INTERFERON INDUCIBLE PROTEIN 10; IMMUNOMODULATING AGENT; INTERLEUKIN 1BETA; INTERLEUKIN 8; LIPOPOLYSACCHARIDE; OM 174; OM 197; OM 294; POLYMYXIN; TOLL LIKE RECEPTOR; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; TRIACYLATED LIPID A LIKE MOLECULE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ARTICLE; CELL STRAIN HEK293; CONTROLLED STUDY; CYTOKINE RELEASE; ESCHERICHIA COLI; HUMAN; HUMAN CELL; KLEBSIELLA PNEUMONIAE; LEUKOCYTE ACTIVATION; PHAGOCYTOSIS; PRIORITY JOURNAL; STAPHYLOCOCCUS AUREUS;

GRAM-NEGATIVE BACTERIA; HEK293 CELLS; HUMANS; IMMUNOLOGIC FACTORS; LIPID A; LYMPHOCYTE ANTIGEN 96; TOLL-LIKE RECEPTOR 2; TOLL-LIKE RECEPTOR 4;

BACTERIA (MICROORGANISMS); MAMMALIA; NEGIBACTERIA;

EID: 84860857242     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.348383     Document Type: Article

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