Physicochemical and biological analysis of synthetic bacterial lipopeptides: Validity of the concept of endotoxic conformation

Journal of Biological Chemistry

Volumn 282, Issue 15, 2007, Pages 11030-11037

  Schromm, Andra B ^a,b   Howe, Jörg ^c   Ulmer, Artur J ^d   Wiesmüller, Karl Heinz ^e   Seyberth, Tobias ^f   Jung, Günther ^f   Rössle, Manfred ^g   Koch, Michel H J ^g   Gutsmann, Thomas ^c   Brandenburg, Klaus ^c  

^a RESEARCH CENTER BORSTEL   (Germany)

^b Emmy Noether Group of Immunobiophysics   (Germany)

^c Division of Biophysics   (Germany)

^d Division of Immunology   (Germany)

^e EMC MICROCOLLECTIONS GMBH   (Germany)

^f UNIVERSITY OF TÜBINGEN   (Germany)

^g EUROPEAN MOLECULAR BIOLOGY LABORATORY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

AMPHIPHILIC COMPONENTS; IMMUNE SYSTEM; LIPOPEPTIDES; LIPOPOLYSACCHARIDE (LPS);

BACTERIA; BIOACTIVITY; BIOLOGICAL MEMBRANES; CONFORMATIONS; IMMUNOLOGY; POLYSACCHARIDES;

PEPTIDES;

ANTIBIOTIC AGENT; CYTOKINE; LIPOLANTHIONINE; LIPOPEPTIDE; LIPOPOLYSACCHARIDE; POLYMYXIN B; SYNTHETIC PEPTIDE; UNCLASSIFIED DRUG; LIPOPROTEIN; PEPTIDE FRAGMENT; TOLL LIKE RECEPTOR 2; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; BIOLOGICAL ACTIVITY; CELL ACTIVATION; CONFORMATION; CONTROLLED STUDY; DRUG ACTIVITY; DRUG MECHANISM; EMBRYO; EXPERIMENTAL STUDY; GEOMETRY; HUMAN; HUMAN CELL; MEMBRANE; MONONUCLEAR CELL; NONHUMAN; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; VALIDITY; BIOSYNTHESIS; CELL CULTURE; CELL MEMBRANE; CHEMICAL STRUCTURE; CHEMISTRY; DRUG ANTAGONISM; DRUG EFFECT; ENZYMOLOGY; MACROPHAGE; MACROPHAGE ACTIVATION; METABOLISM; PROTEIN BINDING; PROTEIN CONFORMATION; SYNTHESIS;

BACTERIA (MICROORGANISMS); NEGIBACTERIA; POSIBACTERIA;

CELL MEMBRANE; CELLS, CULTURED; CHEMISTRY, PHYSICAL; HUMANS; LIPOPOLYSACCHARIDES; LIPOPROTEINS; MACROPHAGE ACTIVATION; MACROPHAGES; MOLECULAR STRUCTURE; PEPTIDE FRAGMENTS; POLYMYXIN B; PROTEIN BINDING; PROTEIN CONFORMATION; TOLL-LIKE RECEPTOR 2; TUMOR NECROSIS FACTOR-ALPHA;

EID: 34249678347     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M700287200     Document Type: Article

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