Structure-based computational analysis of protein binding sites for function and druggability prediction

Journal of Biotechnology

Volumn 159, Issue 3, 2012, Pages 123-134

  Nisius, Britta ^a   Sha, Fan ^a   Gohlke, Holger ^a  

^a HEINRICH HEINE UNIVERSITY   (Germany)

Author keywords

Computational analysis; Druggability; Protein binding sites; Protein function prediction; Protein structure

Indexed keywords

COMPUTATIONAL ANALYSIS; DRUGGABILITY; PROTEIN FUNCTION PREDICTION; PROTEIN STRUCTURES; PROTEIN-BINDING SITES;

COMPUTATIONAL METHODS; PROTEINS;

BINDING SITES;

ARTICLE; BINDING SITE; DRUG TARGETING; PHYSICAL CHEMISTRY; PREDICTION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN BINDING SITE; PROTEIN CONFORMATION; PROTEIN FUNCTION; PROTEIN PROCESSING; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; STRUCTURE BASED COMPUTATIONAL ANALYSIS;

BINDING SITES; COMPUTATIONAL BIOLOGY; DRUG DISCOVERY; MODELS, MOLECULAR; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEINS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84860838201     PISSN: 01681656     EISSN: 18734863     Source Type: Journal    
DOI: 10.1016/j.jbiotec.2011.12.005     Document Type: Article

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