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Volumn 32, Issue 19, 2012, Pages 6561-6569

Transglutaminase inhibition protects against oxidative stress-induced neuronal death downstream of pathological ERK activation

Author keywords

[No Author keywords available]

Indexed keywords

ANIMALS; CELL DEATH; CELLS, CULTURED; DOWN-REGULATION; ENZYME ACTIVATION; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; GTP-BINDING PROTEINS; MALE; MICE; MICE, 129 STRAIN; MICE, INBRED C57BL; MICE, KNOCKOUT; NEURONS; NEUROPROTECTIVE AGENTS; OXIDATIVE STRESS; RATS; RATS, SPRAGUE-DAWLEY; TRANSGLUTAMINASES;

EID: 84860656136     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.3353-11.2012     Document Type: Article
Times cited : (55)

References (55)
  • 1
    • 0041816056 scopus 로고    scopus 로고
    • Opposing rolesof Ras/Raf oncogenes and the MEK1/ERK signaling module in regulation of expression and adhesive function of surface transglutaminase
    • Akimov SS, Belkin AM (2003) Opposing rolesof Ras/Raf oncogenes and the MEK1/ERK signaling module in regulation of expression and adhesive function of surface transglutaminase. J Biol Chem 278:35609-35619.
    • (2003) J Biol Chem , vol.278 , pp. 35609-35619
    • Akimov, S.S.1    Belkin, A.M.2
  • 3
    • 33746275522 scopus 로고    scopus 로고
    • The protective effects of cystamine in the R6/2 Huntington's disease mouse involve mechanisms other than the inhibition of tissue transglutaminase
    • Bailey CD, Johnson GV (2006) The protective effects of cystamine in the R6/2 Huntington's disease mouse involve mechanisms other than the inhibition of tissue transglutaminase. Neurobiol Aging 27:871-879.
    • (2006) Neurobiol Aging , vol.27 , pp. 871-879
    • Bailey, C.D.1    Johnson, G.V.2
  • 4
    • 82755187317 scopus 로고    scopus 로고
    • Extracellular TG2: Emerging functions and regulation
    • Belkin AM (2011) Extracellular TG2: emerging functions and regulation. FEBS J 278:4704-4716.
    • (2011) FEBS J , vol.278 , pp. 4704-4716
    • Belkin, A.M.1
  • 6
    • 77953067720 scopus 로고    scopus 로고
    • Critical role of transglutaminase and other stress proteins during neurodegenerative processes
    • Caccamo D, Currò M, Condello S, Ferlazzo N, Ientile R (2010) Critical role of transglutaminase and other stress proteins during neurodegenerative processes. Amino Acids 38:653-658.
    • (2010) Amino Acids , vol.38 , pp. 653-658
    • Caccamo, D.1    Currò, M.2    Condello, S.3    Ferlazzo, N.4    Ientile, R.5
  • 7
    • 80055029604 scopus 로고    scopus 로고
    • Roles of oxidative stress, apoptosis, PGC-1alpha and mitochondrial biogenesis in cerebral ischemia
    • Chen SD, Yang DI, Lin TK, Shaw FZ, Liou CW, Chuang YC (2011) Roles of oxidative stress, apoptosis, PGC-1alpha and mitochondrial biogenesis in cerebral ischemia. Int J Mol Sci 12:7199-7215.
    • (2011) Int J Mol Sci , vol.12 , pp. 7199-7215
    • Chen, S.D.1    Yang, D.I.2    Lin, T.K.3    Shaw, F.Z.4    Liou, C.W.5    Chuang, Y.C.6
  • 9
    • 33947495568 scopus 로고    scopus 로고
    • A novel cell-permeable antioxidant peptide, SS31, attenuates ischemic brain injury by down-regulating CD36
    • Cho S, Szeto HH, Kim E, Kim H, Tolhurst AT, Pinto JT (2007) A novel cell-permeable antioxidant peptide, SS31, attenuates ischemic brain injury by down-regulating CD36. J Biol Chem 282:4634-4642.
    • (2007) J Biol Chem , vol.282 , pp. 4634-4642
    • Cho, S.1    Szeto, H.H.2    Kim, E.3    Kim, H.4    Tolhurst, A.T.5    Pinto, J.T.6
  • 11
    • 84856574714 scopus 로고    scopus 로고
    • Complete transglutaminase 2 ablation results in reduced stroke volumes and astrocytes that exhibit increased survival in response to ischemia
    • Colak G, Johnson GV (2012) Complete transglutaminase 2 ablation results in reduced stroke volumes and astrocytes that exhibit increased survival in response to ischemia. Neurobiol Dis 45:1042-1050.
    • (2012) Neurobiol Dis , vol.45 , pp. 1042-1050
    • Colak, G.1    Johnson, G.V.2
  • 12
    • 79551615954 scopus 로고    scopus 로고
    • Cytosolic guanine nucledotide binding deficient form of transglutaminase 2 (R580a) potentiates cell death in oxygen glucose deprivation
    • Colak G, Keillor JW, Johnson GV (2011) Cytosolic guanine nucledotide binding deficient form of transglutaminase 2 (R580a) potentiates cell death in oxygen glucose deprivation. PLoS One 6:e16665.
    • (2011) PLoS One , vol.6
    • Colak, G.1    Keillor, J.W.2    Johnson, G.V.3
  • 17
    • 0036312393 scopus 로고    scopus 로고
    • Injury-induced "switch" from GTP-regulated to novel GTP-independent isoform of tissue transglutaminase in the rat spinal cord
    • Festoff BW, SantaCruz K, Arnold PM, Sebastian CT, Davies PJ, Citron BA (2002) Injury-induced "switch" from GTP-regulated to novel GTP-independent isoform of tissue transglutaminase in the rat spinal cord. J Neurochem 81:708-718.
    • (2002) J Neurochem , vol.81 , pp. 708-718
    • Festoff, B.W.1    Santacruz, K.2    Arnold, P.M.3    Sebastian, C.T.4    Davies, P.J.5    Citron, B.A.6
  • 19
    • 0036901574 scopus 로고    scopus 로고
    • Transglutaminases: Nature's biological glues
    • Griffin M, Casadio R, Bergamini CM (2002) Transglutaminases: nature's biological glues. Biochem J 368:377-396.
    • (2002) Biochem J , vol.368 , pp. 377-396
    • Griffin, M.1    Casadio, R.2    Bergamini, C.M.3
  • 21
    • 33846855791 scopus 로고    scopus 로고
    • Different mechanisms account for extracellular-signal regulated kinase activation in distinct brain regions following global ischemia and reperfusion
    • Ho Y, Logue E, Callaway CW, DeFranco DB (2007) Different mechanisms account for extracellular-signal regulated kinase activation in distinct brain regions following global ischemia and reperfusion. Neuroscience 145:248-255.
    • (2007) Neuroscience , vol.145 , pp. 248-255
    • Ho, Y.1    Logue, E.2    Callaway, C.W.3    Defranco, D.B.4
  • 24
    • 67651071286 scopus 로고    scopus 로고
    • Transglutaminases and disease: Lessons from genetically engineered mouse models and inherited disorders
    • Iismaa SE, Mearns BM, Lorand L, Graham RM (2009) Transglutaminases and disease: lessons from genetically engineered mouse models and inherited disorders. Physiol Rev 89:991-1023.
    • (2009) Physiol Rev , vol.89 , pp. 991-1023
    • Iismaa, S.E.1    Mearns, B.M.2    Lorand, L.3    Graham, R.M.4
  • 25
    • 0033594894 scopus 로고    scopus 로고
    • Transglutaminase aggregates huntingtin into nonamyloidogenic polymers, and its enzymatic activity increases in Huntington's disease brain nuclei
    • Karpuj MV, Garren H, Slunt H, Price DL, Gusella J, Becher MW, Steinman L (1999) Transglutaminase aggregates huntingtin into nonamyloidogenic polymers, and its enzymatic activity increases in Huntington's disease brain nuclei. Proc Natl Acad Sci U S A 96:7388-7393.
    • (1999) Proc Natl Acad Sci U S A , vol.96 , pp. 7388-7393
    • Karpuj, M.V.1    Garren, H.2    Slunt, H.3    Price, D.L.4    Gusella, J.5    Becher, M.W.6    Steinman, L.7
  • 26
    • 0036134819 scopus 로고    scopus 로고
    • Evidence for a role for trans-glutaminase in Huntington's disease and the potential therapeutic implications
    • Karpuj MV, Becher MW, Steinman L (2002) Evidence for a role for trans-glutaminase in Huntington's disease and the potential therapeutic implications. Neurochem Int 40:31-36.
    • (2002) Neurochem Int , vol.40 , pp. 31-36
    • Karpuj, M.V.1    Becher, M.W.2    Steinman, L.3
  • 27
    • 44649087184 scopus 로고    scopus 로고
    • CD36/ fatty acid translocase, an inflammatory mediator, is involved in hyperlipidemia-induced exacerbation in ischemic brain injury
    • Kim E, Tolhurst AT, Qin LY, Chen XY, Febbraio M, Cho S (2008) CD36/ fatty acid translocase, an inflammatory mediator, is involved in hyperlipidemia-induced exacerbation in ischemic brain injury. J Neuro-sci 28:4661-4670.
    • (2008) J Neuro-sci , vol.28 , pp. 4661-4670
    • Kim, E.1    Tolhurst, A.T.2    Qin, L.Y.3    Chen, X.Y.4    Febbraio, M.5    Cho, S.6
  • 29
    • 38149116286 scopus 로고    scopus 로고
    • Pulse inhibition of his-tone deacetylases induces complete resistance to oxidative death in cortical neurons without toxicity and reveals a role for cytoplasmic p21(waf1/ cip1) in cell cycle-independent neuroprotection
    • Langley B, D'Annibale MA, Suh K, Ayoub I, Tolhurst A, Bastan B, Yang L, Ko B, Fisher M, Cho S, Beal MF, Ratan RR (2008) Pulse inhibition of his-tone deacetylases induces complete resistance to oxidative death in cortical neurons without toxicity and reveals a role for cytoplasmic p21(waf1/ cip1) in cell cycle-independent neuroprotection. J Neurosci 28:163-176.
    • (2008) J Neurosci , vol.28 , pp. 163-176
    • Langley, B.1    D'annibale, M.A.2    Suh, K.3    Ayoub, I.4    Tolhurst, A.5    Bastan, B.6    Yang, L.7    Ko, B.8    Fisher, M.9    Cho, S.10    Beal, M.F.11    Ratan, R.R.12
  • 30
    • 70350365391 scopus 로고    scopus 로고
    • Inhibition of prolyl hydroxylase protects against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity: Model for the potential involvementofthe hypoxia-inducible factor pathway in Parkinson disease
    • Lee DW, Rajagopalan S, Siddiq A, Gwiazda R, Yang L, Beal MF, Ratan RR, Andersen JK (2009) Inhibition of prolyl hydroxylase protects against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity: model for the potential involvementofthe hypoxia-inducible factor pathway in Parkinson disease. J Biol Chem 284:29065-29076.
    • (2009) J Biol Chem , vol.284 , pp. 29065-29076
    • Lee, D.W.1    Rajagopalan, S.2    Siddiq, A.3    Gwiazda, R.4    Yang, L.5    Beal, M.F.6    Ratan, R.R.7    Andersen, J.K.8
  • 31
    • 0026689033 scopus 로고
    • Identification of transglutaminase substrates in HT29 colon cancer cells: Use of 5-(biotinamido)pentylamine as a transglutaminase-specific probe
    • Lee KN, Maxwell MD, Patterson MK Jr, Birckbichler PJ, Conway E (1992) Identification of transglutaminase substrates in HT29 colon cancer cells: use of 5-(biotinamido)pentylamine as a transglutaminase-specific probe. Biochim Biophys Acta 1136:12-16.
    • (1992) Biochim Biophys Acta , vol.1136 , pp. 12-16
    • Lee, K.N.1    Maxwell, M.D.2    Patterson Jr., M.K.3    Birckbichler, P.J.4    Conway, E.5
  • 32
    • 0037423204 scopus 로고    scopus 로고
    • Cystamine inhibits caspase activity. Implications for the treatment of polyglutamine disorders
    • Lesort M, Lee M, Tucholski J, Johnson GV (2003) Cystamine inhibits caspase activity. Implications for the treatment of polyglutamine disorders. J Biol Chem 278:3825-3830.
    • (2003) J Biol Chem , vol.278 , pp. 3825-3830
    • Lesort, M.1    Lee, M.2    Tucholski, J.3    Johnson, G.V.4
  • 33
    • 44149123762 scopus 로고    scopus 로고
    • Differential activation of extracellular signal-regulated kinase 1 and a related complex in neuronal nuclei
    • Lundquist JJ, Dudek SM (2006) Differential activation of extracellular signal-regulated kinase 1 and a related complex in neuronal nuclei. Brain Cell Biol 35:267-281.
    • (2006) Brain Cell Biol , vol.35 , pp. 267-281
    • Lundquist, J.J.1    Dudek, S.M.2
  • 34
    • 79953286790 scopus 로고    scopus 로고
    • Possible role of the transglutami-nases in the pathogenesis of Alzheimer's disease and other neurodegen-erative diseases
    • Martin A, De Vivo G, Gentile V (2011) Possible role of the transglutami-nases in the pathogenesis of Alzheimer's disease and other neurodegen-erative diseases. Int J Alzheimers Dis 2011:865432.
    • (2011) Int J Alzheimers Dis , pp. 865432
    • Martin, A.1    de Vivo, G.2    Gentile, V.3
  • 37
    • 79955456732 scopus 로고    scopus 로고
    • Mutant huntingtin causes defective actin remodeling during stress: Defining a new role for transglutaminase 2 in neurodegen-erative disease
    • Munsie L, Caron N, Atwal RS, Marsden I, Wild EJ, Bamburg JR, Tabrizi SJ, Truant R (2011) Mutant huntingtin causes defective actin remodeling during stress: defining a new role for transglutaminase 2 in neurodegen-erative disease. Hum Mol Genet 20:1937-1951.
    • (2011) Hum Mol Genet , vol.20 , pp. 1937-1951
    • Munsie, L.1    Caron, N.2    Atwal, R.S.3    Marsden, I.4    Wild, E.J.5    Bamburg, J.R.6    Tabrizi, S.J.7    Truant, R.8
  • 38
    • 0024678458 scopus 로고
    • Gluta-mate toxicity in a neuronal cell line involves inhibition of cystine transport leading to oxidative stress
    • Murphy TH, Miyamoto M, Sastre A, Schnaar RL, Coyle JT (1989) Gluta-mate toxicity in a neuronal cell line involves inhibition of cystine transport leading to oxidative stress. Neuron 2:1547-1558.
    • (1989) Neuron , vol.2 , pp. 1547-1558
    • Murphy, T.H.1    Miyamoto, M.2    Sastre, A.3    Schnaar, R.L.4    Coyle, J.T.5
  • 40
    • 58149122816 scopus 로고    scopus 로고
    • Tissue-type transglutaminase and the effects of cystamine on intracerebral hemorrhage-induced brain edema and neurological deficits
    • Okauchi M, Xi G, Keep RF, Hua Y (2009) Tissue-type transglutaminase and the effects of cystamine on intracerebral hemorrhage-induced brain edema and neurological deficits. Brain Res 1249:229-236.
    • (2009) Brain Res , vol.1249 , pp. 229-236
    • Okauchi, M.1    Xi, G.2    Keep, R.F.3    Hua, Y.4
  • 42
    • 0028095981 scopus 로고
    • Oxidative stress induces apo-ptosis in embryonic cortical neurons
    • Ratan RR, Murphy TH, Baraban JM (1994) Oxidative stress induces apo-ptosis in embryonic cortical neurons. J Neurochem 62:376-379.
    • (1994) J Neurochem , vol.62 , pp. 376-379
    • Ratan, R.R.1    Murphy, T.H.2    Baraban, J.M.3
  • 43
    • 0037868957 scopus 로고    scopus 로고
    • Sp1 and Sp3 are oxidative stress-inducible, antideath transcription factors in cortical neurons
    • Ryu H, Lee J, Zaman K, Kubilis J, Ferrante RJ, Ross BD, Neve R, Ratan RR (2003) Sp1 and Sp3 are oxidative stress-inducible, antideath transcription factors in cortical neurons. J Neurosci 23:3597-3606.
    • (2003) J Neurosci , vol.23 , pp. 3597-3606
    • Ryu, H.1    Lee, J.2    Zaman, K.3    Kubilis, J.4    Ferrante, R.J.5    Ross, B.D.6    Neve, R.7    Ratan, R.R.8
  • 45
    • 0030988138 scopus 로고    scopus 로고
    • Nitric oxide synthase in models of focal ischemia
    • Samdani AF, Dawson TM, Dawson VL (1997) Nitric oxide synthase in models of focal ischemia. Stroke 28:1283-1288.
    • (1997) Stroke , vol.28 , pp. 1283-1288
    • Samdani, A.F.1    Dawson, T.M.2    Dawson, V.L.3
  • 51
    • 0032526940 scopus 로고    scopus 로고
    • The regulation of reactive oxygen species production during programmed cell death
    • Tan S, Sagara Y, Liu Y, Maher P, Schubert D (1998) The regulation of reactive oxygen species production during programmed cell death. J Cell Biol 141:1423-1432.
    • (1998) J Cell Biol , vol.141 , pp. 1423-1432
    • Tan, S.1    Sagara, Y.2    Liu, Y.3    Maher, P.4    Schubert, D.5
  • 53
    • 2642518688 scopus 로고    scopus 로고
    • Increased expression of tissue-type transglutaminase following middle cerebral artery occlusion in rats
    • Tolentino PJ, Waghray A, Wang KK, Hayes RL (2004) Increased expression of tissue-type transglutaminase following middle cerebral artery occlusion in rats. J Neurochem 89:1301-1307.
    • (2004) J Neurochem , vol.89 , pp. 1301-1307
    • Tolentino, P.J.1    Waghray, A.2    Wang, K.K.3    Hayes, R.L.4
  • 54
    • 0037216665 scopus 로고    scopus 로고
    • Significant neuroprotection against ischemic brain injury by inhibition of the MEK1 protein kinase in mice: Exploration of potential mechanism associated with apoptosis
    • Wang X, Wang H, Xu L, Rozanski DJ, Sugawara T, Chan PH, Trzaskos JM, Feuerstein GZ (2003) Significant neuroprotection against ischemic brain injury by inhibition of the MEK1 protein kinase in mice: exploration of potential mechanism associated with apoptosis. J Pharmacol Exp Ther 304:172-178.
    • (2003) J Pharmacol Exp Ther , vol.304 , pp. 172-178
    • Wang, X.1    Wang, H.2    Xu, L.3    Rozanski, D.J.4    Sugawara, T.5    Chan, P.H.6    Trzaskos, J.M.7    Feuerstein, G.Z.8
  • 55
    • 0033571939 scopus 로고    scopus 로고
    • Protection from oxidative stress-induced apoptosis in cortical neuronal cultures by iron chelators is associated with enhanced DNA binding of hypoxia-inducible factor-1 and ATF-1/CREB and increased expression of glycolytic enzymes, p21(waf1/cip1), and erythropoietin
    • Zaman K, Ryu H, Hall D, O'Donovan K, Lin KI, Miller MP, Marquis JC, Baraban JM, Semenza GL, Ratan RR (1999) Protection from oxidative stress-induced apoptosis in cortical neuronal cultures by iron chelators is associated with enhanced DNA binding of hypoxia-inducible factor-1 and ATF-1/CREB and increased expression of glycolytic enzymes, p21(waf1/cip1), and erythropoietin. J Neurosci 19:9821-9830.
    • (1999) J Neurosci , vol.19 , pp. 9821-9830
    • Zaman, K.1    Ryu, H.2    Hall, D.3    O'Donovan, K.4    Lin, K.I.5    Miller, M.P.6    Marquis, J.C.7    Baraban, J.M.8    Semenza, G.L.9    Ratan, R.R.10


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.