Tissue-type transglutaminase and the effects of cystamine on intracerebral hemorrhage-induced brain edema and neurological deficits

Brain Research

Volumn 1249, Issue , 2009, Pages 229-236

  Okauchi, Masanobu ^a   Xi, Guohua ^a   Keep, Richard F ^a   Hua, Ya ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

Brain swelling; Cerebral hemorrhage; Cystamine; Tissue type transglutaminase

Indexed keywords

CYSTAMINE; PROTEIN GLUTAMINE GAMMA GLUTAMYLTRANSFERASE; TISSUE TYPE TRANSGLUTAMINASE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN EDEMA; BRAIN HEMORRHAGE; CONTROLLED STUDY; DRUG EFFECT; FUNCTIONAL ASSESSMENT; IMMUNOHISTOCHEMISTRY; NERVE CELL NECROSIS; NEUROLOGIC DISEASE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; RAT; REAL TIME POLYMERASE CHAIN REACTION; SPRAGUE DAWLEY RAT; TASK PERFORMANCE; WESTERN BLOTTING;

ANIMALS; BASAL GANGLIA; BLOTTING, WESTERN; BRAIN CHEMISTRY; BRAIN EDEMA; CEREBRAL HEMORRHAGE; CYSTAMINE; ENZYME INHIBITORS; GENE EXPRESSION; GTP-BINDING PROTEINS; IMMUNOHISTOCHEMISTRY; MALE; NERVE DEGENERATION; POLYMERASE CHAIN REACTION; RATS; RATS, SPRAGUE-DAWLEY; RECOVERY OF FUNCTION; RNA, MESSENGER; TRANSGLUTAMINASES;

RATTUS;

EID: 58149122816     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainres.2008.10.035     Document Type: Article

References (44)

1. Bailey C.D., and Johnson G.V. The protective effects of cystamine in the R6/2 Huntington's disease mouse involve mechanisms other than the inhibition of tissue transglutaminase. Neurobiol. Aging 27 (2006) 871-879
2. Borrell-Pages M., Canals J.M., Cordelieres F.P., Parker J.A., Pineda J.R., Grange G., Bryson E.A., Guillermier M., Hirsch E., Hantraye P., Cheetham M.E., Neri C., Alberch J., Brouillet E., Saudou F., and Humbert S. Cystamine and cysteamine increase brain levels of BDNF in Huntington disease via HSJ1b and transglutaminase. J. Clin. Invest. 116 (2006) 1410-1424
3. Citron B.A., Suo Z., SantaCruz K., Davies P.J., Qin F., and Festoff B.W. Protein crosslinking, tissue transglutaminase, alternative splicing and neurodegeneration. Neurochem. Int. 40 (2002) 69-78
4. Festoff B.W., SantaCruz K., Arnold P.M., Sebastian C.T., Davies P.J., and Citron B.A. Injury-induced "switch" from GTP-regulated to novel GTP-independent isoform of tissue transglutaminase in the rat spinal cord. J. Neurochem. 81 (2002) 708-718
5. Fesus L. Transglutaminase-catalyzed protein cross-linking in the molecular program of apoptosis and its relationship to neuronal processes. Cell. Mol. Neurobiol. 18 (1998) 683-694
6. Fujita K., Kato T., Shibayama K., Imada H., Yamauchi M., Yoshimoto N., Miyachi E., and Nagata Y. Protective effect against 17beta-estradiol on neuronal apoptosis in hippocampus tissue following transient ischemia/recirculation in Mongolian gerbils via down-regulation of tissue transglutaminase activity. Neurochem. Res. 31 (2006) 1059-1068
7. Gong C., Boulis N., Qian J., Turner D.E., Hoff J.T., and Keep R.F. Intracerebral hemorrhage-induced neuronal death. Neurosurgery 48 (2001) 875-883
8. Hua Y., Schallert T., Keep R.F., Wu J., Hoff J.T., and Xi G. Behavioral tests after intracerebral hemorrhage in the rat. Stroke 33 (2002) 2478-2484
9. Huang F., Xi G., Keep R.F., Hua Y., Nemoianu A., and Hoff J.T. Brain edema after experimental intracerebral hemorrhage: role of hemoglobin degradation products. J. Neurosurg. 96 (2002) 287-293
10. Ientile R., Campisi A., Raciti G., Caccamo D., Curro M., Cannavo G., Li Volti G., Macaione S., and Vanella A. Cystamine inhibits transglutaminase and caspase-3 cleavage in glutamate-exposed astroglial cells. J. Neurosci. Res. 74 (2003) 52-59
11. Ientile R., Caccamo D., Marciano M.C., Curro M., Mannucci C., Campisi A., and Calapai G. Transglutaminase activity and transglutaminase mRNA transcripts in gerbil brain ischemia. Neurosci. Lett. 363 (2004) 173-177
12. Igarashi S., Koide R., Shimohata T., Yamada M., Hayashi Y., Takano H., Date H., Oyake M., Sato T., Sato A., Egawa S., Ikeuchi T., Tanaka H., Nakano R., Tanaka K., Hozumi I., Inuzuka T., Takahashi H., and Tsuji S. Suppression of aggregate formation and apoptosis by transglutaminase inhibitors in cells expressing truncated DRPLA protein with an expanded polyglutamine stretch. Nat. Genet. 18 (1998) 111-117
13. Karpuj M.V., Becher M.W., Springer J.E., Chabas D., Youssef S., Pedotti R., Mitchell D., and Steinman L. Prolonged survival and decreased abnormal movements in transgenic model of Huntington disease, with administration of the transglutaminase inhibitor cystamine. [erratum appears in Nat. Med. 2002 Mar;8(3):303]. Nat. Med. 8 (2002) 143-149
14. Kim S.Y. Transglutaminase 2 in inflammation. Front. Biosci. 11 (2006) 3026-3035
15. Kim S.Y., Grant P., Lee J.H., Pant H.C., and Steinert P.M. Differential expression of multiple transglutaminases in human brain. Increased expression and cross-linking by transglutaminases 1 and 2 in Alzheimer's disease. J. Biol. Chem. 274 (1999) 30715-30721
16. Kingman T.A., Mendelow A.D., Graham D.I., and Teasdale G.M. Experimental intracerebral mass: description of model, intracranial pressure changes and neuropathology. J. Neuropathol. Exp. Neurol. 47 (1988) 128-137
17. Lee J., Kim Y.S., Choi D.H., Bang M.S., Han T.R., Joh T.H., and Kim S.Y. Transglutaminase 2 induces nuclear factor-kappaB activation via a novel pathway in BV-2 microglia. J. Biol. Chem. 279 (2004) 53725-53735
18. Lesort M., Tucholski J., Miller M.L., and Johnson G.V. Tissue transglutaminase: a possible role in neurodegenerative diseases. Prog. Neurobiol. 61 (2000) 439-463
19. Lesort M., Lee M., Tucholski J., and Johnson G.V. Cystamine inhibits caspase activity. Implications for the treatment of polyglutamine disorders. J. Biol. Chem. 278 (2003) 3825-3830
20. Lu T., Pan Y., Kao S.Y., Li C., Kohane I., Chan J., and Yankner B.A. Gene regulation and DNA damage in the ageing human brain. Nature 429 (2004) 883-891
21. Maggio N., Sellitti S., Capano C.P., and Papa M. Tissue-transglutaminase in rat and human brain: light and electron immunocytochemical analysis and in situ hybridization study. Brain Res. Bull. 56 (2001) 173-182
22. Matsushita K., Meng W., Wang X., Asahi M., Asahi K., Moskowitz M.A., and Lo E.H. Evidence for apoptosis after intercerebral hemorrhage in rat striatum. J. Cereb. Blood Flow Metab. 20 (2000) 396-404
23. Mendelow A.D., Gregson B.A., Fernandes H.M., Murray G.D., Teasdale G.M., Hope D.T., Karimi A., Shaw M.D., Barer D.H., and investigators S. Early surgery versus initial conservative treatment in patients with spontaneous supratentorial intracerebral haematomas in the International Surgical Trial in Intracerebral Haemorrhage (STICH): a randomised trial. [see comment]. Lancet 365 (2005) 387-397
24. Nakamura T., Hua Y., Keep R.F., Park J.W., Xi G., and Hoff J.T. Estrogen therapy for experimental intracerebral hemorrhage in rats. J. Neurosurg. 103 (2005) 97-103
25. Namura S., Zhu J., Fink K., Endres M., Srinivasan A., Tomaselli K.J., Yuan J., and Moskowitz M.A. Activation and cleavage of caspase-3 in apoptosis induced by experimental cerebral ischemia. J. Neurosci. 18 (1998) 3659-3668
26. Piacentini M., Farrace M.G., Piredda L., Matarrese P., Ciccosanti F., Falasca L., Rodolfo C., Giammarioli A.M., Verderio E., Griffin M., and Malorni W. Transglutaminase overexpression sensitizes neuronal cell lines to apoptosis by increasing mitochondrial membrane potential and cellular oxidative stress. J. Neurochem. 81 (2002) 1061-1072
27. Piacentini M., Amendola A., Ciccosanti F., Falasca L., Farrace M.G., Mastroberardino P.G., Nardacci R., Oliverio S., Piredda L., Rodolfo C., and Autuori F. Type 2 transglutaminase and cell death. Prog. Exp. Tumor Res. 38 (2005) 58-74
28. Pinto J.T., Van Raamsdonk J.M., Leavitt B.R., Hayden M.R., Jeitner T.M., Thaler H.T., Krasnikov B.F., and Cooper A.J. Treatment of YAC128 mice and their wild-type littermates with cystamine does not lead to its accumulation in plasma or brain: implications for the treatment of Huntington disease. J. Neurochem. 94 (2005) 1087-1101
29. Qureshi A.I., Ling G.S., Khan J., Suri M.F., Miskolczi L., Guterman L.R., and Hopkins L.N. Quantitative analysis of injured, necrotic, and apoptotic cells in a new experimental model of intracerebral hemorrhage. Crit. Care Med. 29 (2001) 152-157
30. Qureshi A.I., Suri M.F., Ostrow P.T., Kim S.H., Ali Z., Shatla A.A., Guterman L.R., and Hopkins L.N. Apoptosis as a form of cell death in intracerebral hemorrhage. Neurosurgery 52 (2003) 1041-1047 discussion 1047-8
31. Schmued L.C., Albertson C., and Slikker Jr. W. Fluoro-Jade: a novel fluorochrome for the sensitive and reliable histochemical localization of neuronal degeneration. Brain Res. 751 (1997) 37-46
32. Tolentino P.J., DeFord S.M., Notterpek L., Glenn C.C., Pike B.R., Wang K.K., and Hayes R.L. Up-regulation of tissue-type transglutaminase after traumatic brain injury. J. Neurochem. 80 (2002) 579-588
33. Tolentino P.J., Waghray A., Wang K.K., and Hayes R.L. Increased expression of tissue-type transglutaminase following middle cerebral artery occlusion in rats. J. Neurochem. 89 (2004) 1301-1307
34. Tucholski J., Roth K.A., and Johnson G.V. Tissue transglutaminase overexpression in the brain potentiates calcium-induced hippocampal damage. J. Neurochem. 97 (2006) 582-594
35. Van Raamsdonk J.M., Pearson J., Bailey C.D., Rogers D.A., Johnson G.V., Hayden M.R., and Leavitt B.R. Cystamine treatment is neuroprotective in the YAC128 mouse model of Huntington disease. J. Neurochem. 95 (2005) 210-220
36. Wang X., Sarkar A., Cicchetti F., Yu M., Zhu A., Jokivarsi K., Saint-Pierre M., and Brownell A.L. Cerebral PET imaging and histological evidence of transglutaminase inhibitor cystamine induced neuroprotection in transgenic R6/2 mouse model of Huntington's disease. J. Neurol. Sci. 231 (2005) 57-66
37. Wu J., Hua Y., Keep R.F., Schallert T., Hoff J., and Xi G. Oxidative brain injury from extravasated erythrocytes after intracerebral hemorrhage. Brain Res. 953 (2002) 45
38. Xi G., Keep R.F., and Hoff J.T. Erythrocytes and delayed brain edema formation following intracerebral hemorrhage in rats. J. Neurosurg. 89 (1998) 991-996
39. Xi G., Keep R.F., Hua Y., Xiang J.M., and Hoff J.T. Attenuation of thrombin-induced brain edema by cerebral thrombin preconditioning. Stroke 30 (1999) 1247-1255
40. Xi G., Keep R.F., Hua Y., Bhasin R.R., Duong H.K., and Hoff J.T. Mechanisms of edema formation following intracerebral hemorrhage: does hemolysate cause ischemia in intracerebral hemorrhage?. J. Neurosurg. 94 (2001) 162A
41. Xi G., Keep R.F., and Hoff J.T. Mechanisms of brain injury after intracerebral haemorrhage. Lancet Neurol. 5 (2006) 53-63
42. Yang G.Y., Betz A.L., Chenevert T.L., Brunberg J.A., and Hoff J.T. Experimental intracerebral hemorrhage: relationship between brain edema, blood flow, and blood-brain barrier permeability in rats. J. Neurosurg. 81 (1994) 93-102
43. Zainelli G.M., Dudek N.L., Ross C.A., Kim S.Y., and Muma N.A. Mutant huntingtin protein: a substrate for transglutaminase 1, 2, and 3. J. Neuropathol. Exp. Neurol. 64 (2005) 58-65
44. Zazulia A.R., Diringer M.N., Derdeyn C.P., and Powers W.J. Progression of mass effect after intracerebral hemorrhage. Stroke 30 (1999) 1167-1173