메뉴 건너뛰기




Volumn 297, Issue 5, 2009, Pages

Cholinergic agonists regulate JAK2/STAT3 signaling to suppress endothelial cell activation

Author keywords

GTS 21; Inflammation; Intercellular adhesion molecule 1; Interleukin 6; Monocyte chemoattractant protein 1; Nicotine; Soluble interleukin 6 receptor; Suppressor of cytokine signaling 3

Indexed keywords

3 (2,4 DIMETHOXYBENZYLIDENE)ANABASEINE; CHOLINERGIC RECEPTOR STIMULATING AGENT; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 6; JANUS KINASE 3; MONOCYTE CHEMOTACTIC PROTEIN 1; NICOTINE; ORTHOVANADIC ACID; PROTEIN TYROSINE PHOSPHATASE SHP 1; PROTEIN TYROSINE PHOSPHATASE SHP 2; SODIUM; STAT3 PROTEIN; SUPPRESSOR OF CYTOKINE SIGNALING 3;

EID: 70449635663     PISSN: 03636143     EISSN: 15221563     Source Type: Journal    
DOI: 10.1152/ajpcell.00160.2009     Document Type: Article
Times cited : (100)

References (70)
  • 1
    • 23944476094 scopus 로고    scopus 로고
    • Involvement of IL-6 in the pathogenesis of inflammatory bowel disease and colon cancer
    • DOI 10.1385/CRIAI:28:3:187
    • Atreya R, Neurath MF. Involvement of IL-6 in the pathogenesis of inflammatory bowel disease and colon cancer. Clin Rev Allergy Immunol 28: 187-196, 2005. (Pubitemid 41208908)
    • (2005) Clinical Reviews in Allergy and Immunology , vol.28 , Issue.3 , pp. 187-195
    • Atreya, R.1    Neurath, M.F.2
  • 2
    • 0032749778 scopus 로고    scopus 로고
    • Release of CXC-chemokines by human lung microvascular endothelial cells (LMVEC) compared with macrovascular umbilical vein endothelial cells
    • Beck GC, Yard BA, Breedijk AJ, Van AK, Van Der Woude FJ. Release of CXC-chemokines by human lung microvascular endothelial cells (LMVEC) compared with macrovascular umbilical vein endothelial cells. Clin Exp Immunol 118: 298-303, 1999.
    • (1999) Clin Exp Immunol , vol.118 , pp. 298-303
    • Beck, G.C.1    Yard, B.A.2    Breedijk, A.J.3    Van, A.K.4    Van Der Woude, F.J.5
  • 5
    • 0034635550 scopus 로고    scopus 로고
    • Role of the suppressor of cytokine signaling-3 in mediating the inhibitory effects of interleukin-1beta on the growth hormone-dependent transcription of the acid-labile subunit gene in liver cells
    • DOI 10.1074/jbc.275.6.3841
    • Boisclair YR, Wang J, Shi J, Hurst KR, Ooi GT. Role of the suppressor of cytokine signaling-3 in mediating the inhibitory effects of interleukin- 1beta on the growth hormone-dependent transcription of the acid-labile subunit gene in liver cells. J Biol Chem 275: 3841-3847, 2000. (Pubitemid 30094607)
    • (2000) Journal of Biological Chemistry , vol.275 , Issue.6 , pp. 3841-3847
    • Boisclair, Y.R.1    Wang, J.2    Shi, J.3    Hurst, K.R.4    Ooi, G.T.5
  • 6
    • 58649100056 scopus 로고    scopus 로고
    • Inflammation and cancer: IL-6 and STAT3 complete the link
    • Bromberg J, Wang TC. Inflammation and cancer: IL-6 and STAT3 complete the link. Cancer Cell 15: 79-80, 2009.
    • (2009) Cancer Cell , vol.15 , pp. 79-80
    • Bromberg, J.1    Wang, T.C.2
  • 7
    • 33745054187 scopus 로고    scopus 로고
    • Herbal remedy magnolol suppresses IL-6-induced STAT3 activation and gene expression in endothelial cells
    • Chen SC, Chang YL, Wang DL, Cheng JJ. Herbal remedy magnolol suppresses IL-6-induced STAT3 activation and gene expression in endothelial cells. Br J Pharmacol 148: 226-232, 2006.
    • (2006) Br J Pharmacol , vol.148 , pp. 226-232
    • Chen, S.C.1    Chang, Y.L.2    Wang, D.L.3    Cheng, J.J.4
  • 11
    • 34247101624 scopus 로고    scopus 로고
    • Stimulation of alpha 7 cholinergic receptors inhibits lipopolysaccharide-induced neutrophil recruitment by a tumor necrosis factor alpha-independent mechanism
    • Giebelen IA, van Westerloo DJ, Larosa GJ, de Vos AF, van der PT. Stimulation of alpha 7 cholinergic receptors inhibits lipopolysaccharide-induced neutrophil recruitment by a tumor necrosis factor alpha-independent mechanism. Shock 27: 443-447, 2007.
    • (2007) Shock , vol.27 , pp. 443-447
    • Giebelen, I.A.1    Van Westerloo, D.J.2    Larosa, G.J.3    De Vos, A.F.4    Van Der, P.T.5
  • 12
    • 0032127329 scopus 로고    scopus 로고
    • Regulation of endothelial cell myosin light chain phosphorylation and permeability by vanadate
    • DOI 10.1002/(SICI)1097-4644(19980701)70:1<141::AID-JCB14>3.0.CO;2-S
    • Gilbert-McClain LI, Verin AD, Shi S, Irwin RP, Garcia JG. Regulation of endothelial cell myosin light chain phosphorylation and permeability by vanadate. J Cell Biochem 70: 141-155, 1998. (Pubitemid 28310927)
    • (1998) Journal of Cellular Biochemistry , vol.70 , Issue.1 , pp. 141-155
    • Gilbert-McClain, L.I.1    Verin, A.D.2    Shi, S.3    Irwin, R.P.4    Garcia, J.G.N.5
  • 13
    • 0025953405 scopus 로고
    • Use of vanadate as protein-phosphotyrosine phosphatase inhibitor
    • Gordon JA. Use of vanadate as protein-phosphotyrosine phosphatase inhibitor. Methods Enzymol 201: 477-482, 1991.
    • (1991) Methods Enzymol , vol.201 , pp. 477-482
    • Gordon, J.A.1
  • 16
    • 0029662062 scopus 로고    scopus 로고
    • Pilot trial of nicotine patches as an alternative to corticosteroids in ulcerative colitis
    • Guslandi M, Tittobello A. Pilot trial of nicotine patches as an alternative to corticosteroids in ulcerative colitis. J Gastroenterol 31: 627-629, 1996. (Pubitemid 126723423)
    • (1996) Journal of Gastroenterology , vol.31 , Issue.4 , pp. 627-629
    • Guslandi, M.1    Tittobello, A.2
  • 17
    • 22344453974 scopus 로고    scopus 로고
    • Growth hormone inhibits signal transducer and activator of transcription 3 activation and reduces disease activity in murine colitis
    • DOI 10.1053/j.gastro.2005.05.018, PII S0016508505008887
    • Han X, Sosnowska D, Bonkowski EL, Denson LA. Growth hormone inhibits signal transducer and activator of transcription 3 activation and reduces disease activity in murine colitis. Gastroenterology 129: 185-203, 2005. (Pubitemid 41002054)
    • (2005) Gastroenterology , vol.129 , Issue.1 , pp. 185-203
    • Han, X.1    Sosnowska, D.2    Bonkowski, E.L.3    Denson, L.A.4
  • 18
    • 0025190892 scopus 로고
    • Interleukin-6 and the acute phase response
    • Heinrich PC, Castell JV, Andus T. Interleukin-6 and the acute phase response. Biochem J 265: 621-636, 1990.
    • (1990) Biochem J , vol.265 , pp. 621-636
    • Heinrich, P.C.1    Castell, J.V.2    Andus, T.3
  • 21
    • 54849427454 scopus 로고    scopus 로고
    • JAK2-STAT3 signaling pathway mediates thrombin-induced proinflammatory actions of microglia in vitro
    • Huang C, Ma R, Sun S, Wei G, Fang Y, Liu R, Li G. JAK2-STAT3 signaling pathway mediates thrombin-induced proinflammatory actions of microglia in vitro. J Neuroimmunol 204: 118-125, 2008.
    • (2008) J Neuroimmunol , vol.204 , pp. 118-125
    • Huang, C.1    Ma, R.2    Sun, S.3    Wei, G.4    Fang, Y.5    Liu, R.6    Li, G.7
  • 22
    • 0034960582 scopus 로고    scopus 로고
    • IL-6 and its soluble receptor orchestrate a temporal switch in the pattern of leukocyte recruitment seen during acute inflammation
    • DOI 10.1016/S1074-7613(01)00151-0
    • Hurst SM, Wilkinson TS, McLoughlin RM, Jones S, Horiuchi S, Yamamoto N, Rose-John S, Fuller GM, Topley N, Jones SA. Il-6 and its soluble receptor orchestrate a temporal switch in the pattern of leukocyte recruitment seen during acute inflammation. Immunity 14: 705-714, 2001. (Pubitemid 32592418)
    • (2001) Immunity , vol.14 , Issue.6 , pp. 705-714
    • Hurst, S.M.1    Wilkinson, T.S.2    McLoughlin, R.M.3    Jones, S.4    Horiuchi, S.5    Yamamoto, N.6    Rose-John, S.7    Fuller, G.M.8    Topley, N.9    Jones, S.A.10
  • 23
    • 0041302153 scopus 로고    scopus 로고
    • Negative regulation of cytokine signaling and inflammatory diseases
    • DOI 10.1016/S1471-4892(03)00070-5, PII S1471489203000705
    • Inagaki-Ohara K, Hanada T, Yoshimura A. Negative regulation of cytokine signaling and inflammatory diseases. Curr Opin Pharmacol 3: 435-442, 2003. (Pubitemid 36908948)
    • (2003) Current Opinion in Pharmacology , vol.3 , Issue.4 , pp. 435-442
    • Inagaki-Ohara, K.1    Hanada, T.2    Yoshimura, A.3
  • 25
    • 0015822275 scopus 로고
    • Culture of human endothelial cells derived from umbilical veins. Identification by morphologic and immunologic criteria
    • Jaffe EA, Nachman RL, Becker CG, Minick CR. Culture of human endothelial cells derived from umbilical veins. Identification by morphologic and immunologic criteria. J Clin Invest 52: 2745-2756, 1973.
    • (1973) J Clin Invest , vol.52 , pp. 2745-2756
    • Jaffe, E.A.1    Nachman, R.L.2    Becker, C.G.3    Minick, C.R.4
  • 26
    • 1542297244 scopus 로고    scopus 로고
    • IL-6 signal transduction and its physiological roles: The signal orchestration model
    • Kamimura D, Ishihara K, Hirano T. IL-6 signal transduction and its physiological roles: the signal orchestration model. Rev Physiol Biochem Pharmacol 149: 1-38, 2003.
    • (2003) Rev Physiol Biochem Pharmacol , vol.149 , pp. 1-38
    • Kamimura, D.1    Ishihara, K.2    Hirano, T.3
  • 27
    • 0037213682 scopus 로고    scopus 로고
    • IL-6: A regulator of the transition from neutrophil to monocyte recruitment during inflammation
    • DOI 10.1016/S1471-4906(02)00013-3, PII S1471490602000133
    • Kaplanski G, Marin V, Montero-Julian F, Mantovani A, Farnarier C. IL-6: a regulator of the transition from neutrophil to monocyte recruitment during inflammation. Trends Immunol 24: 25-29, 2003. (Pubitemid 35462110)
    • (2003) Trends in Immunology , vol.24 , Issue.1 , pp. 25-29
    • Kaplanski, G.1    Marin, V.2    Montero-Julian, F.3    Mantovani, A.4    Farnarier, C.5
  • 28
    • 0033626286 scopus 로고    scopus 로고
    • The brain alpha7 nicotinic receptor may be an important therapeutic target for the treatment of Alzheimer's disease: Studies with DMXBA (GTS-21)
    • Kem WR. The brain alpha7 nicotinic receptor may be an important therapeutic target for the treatment of Alzheimer's disease: studies with DMXBA (GTS-21). Behav Brain Res 113: 169-181, 2000.
    • (2000) Behav Brain Res , vol.113 , pp. 169-181
    • Kem, W.R.1
  • 30
    • 0031568002 scopus 로고    scopus 로고
    • Mechanism of sustained E-selectin expression in cultured human dermal microvascular endothelial cells
    • Kluger MS, Johnson DR, Pober JS. Mechanism of sustained E-selectin expression in cultured human dermal microvascular endothelial cells. J Immunol 158: 887-896, 1997.
    • (1997) J Immunol , vol.158 , pp. 887-896
    • Kluger, M.S.1    Johnson, D.R.2    Pober, J.S.3
  • 31
    • 34547951341 scopus 로고    scopus 로고
    • Can the protective actions of JAK-STAT in the heart be exploited therapeutically? Parsing the regulation of interleukin-6-type cytokine signaling
    • DOI 10.1097/FJC.0b013e318068dd49, PII 0000534420070800000005
    • Kurdi M, Booz GW. Can the protective actions of JAK-STAT in the heart be exploited therapeutically? Parsing the regulation of interleukin-6-type cytokine signaling. J Cardiovasc Pharmacol 50: 126-141, 2007. (Pubitemid 47267738)
    • (2007) Journal of Cardiovascular Pharmacology , vol.50 , Issue.2 , pp. 126-141
    • Kurdi, M.1    Booz, G.W.2
  • 32
    • 34548230927 scopus 로고    scopus 로고
    • Getting to the site of inflammation: The leukocyte adhesion cascade updated
    • DOI 10.1038/nri2156, PII NRI2156
    • Ley K, Laudanna C, Cybulsky MI, Nourshargh S. Getting to the site of inflammation: the leukocyte adhesion cascade updated. Nat Rev Immunol 7: 678-689, 2007. (Pubitemid 47327397)
    • (2007) Nature Reviews Immunology , vol.7 , Issue.9 , pp. 678-689
    • Ley, K.1    Laudanna, C.2    Cybulsky, M.I.3    Nourshargh, S.4
  • 34
    • 41149178098 scopus 로고    scopus 로고
    • Human brain microvascular endothelial cells and umbilical vein endothelial cells differentially facilitate leukocyte recruitment and utilize chemokines for T cell migration
    • ID 384982
    • Man S, Ubogu EE, Williams KA, Tucky B, Callahan MK, Ransohoff RM. Human brain microvascular endothelial cells and umbilical vein endothelial cells differentially facilitate leukocyte recruitment and utilize chemokines for T cell migration. Clin Dev Immunol 2008: ID 384982, 2008.
    • (2008) Clin Dev Immunol , vol.2008
    • Man, S.1    Ubogu, E.E.2    Williams, K.A.3    Tucky, B.4    Callahan, M.K.5    Ransohoff, R.M.6
  • 35
    • 0028814601 scopus 로고
    • Regulation of the production of the RANTES chemokine by endothelial cells. Synergistic induction by IFN-gamma plus TNF-alpha and inhibition by IL-4 and IL-13
    • Marfaing-Koka A, Devergne O, Gorgone G, Portier A, Schall TJ, Galanaud P, Emilie D. Regulation of the production of the RANTES chemokine by endothelial cells. Synergistic induction by IFN-gamma plus TNF-alpha and inhibition by IL-4 and IL-13. J Immunol 154: 1870-1878, 1995.
    • (1995) J Immunol , vol.154 , pp. 1870-1878
    • Marfaing-Koka, A.1    Devergne, O.2    Gorgone, G.3    Portier, A.4    Schall, T.J.5    Galanaud, P.6    Emilie, D.7
  • 37
    • 23944473687 scopus 로고    scopus 로고
    • It takes nerve to dampen inflammation
    • Metz CN, Tracey KJ. It takes nerve to dampen inflammation. Nat Immunol 6: 756-757, 2005.
    • (2005) Nat Immunol , vol.6 , pp. 756-757
    • Metz, C.N.1    Tracey, K.J.2
  • 41
    • 0038180539 scopus 로고    scopus 로고
    • Leukocyte-endothelial-cell interactions in leukocyte transmigration and the inflammatory response
    • Muller WA. Leukocyte-endothelial-cell interactions in leukocyte transmigration and the inflammatory response. Trends Immunol 24: 327-334, 2003.
    • (2003) Trends Immunol , vol.24 , pp. 327-334
    • Muller, W.A.1
  • 42
    • 34248642536 scopus 로고    scopus 로고
    • STAT3-mediated anti-inflammatory signalling
    • Murray PJ. STAT3-mediated anti-inflammatory signalling. Biochem Soc Trans 34: 1028-1031, 2006.
    • (2006) Biochem Soc Trans , vol.34 , pp. 1028-1031
    • Murray, P.J.1
  • 45
    • 0034532895 scopus 로고    scopus 로고
    • Adrenocorticotrophic hormone stimulates phosphotyrosine phosphatase SHP2 in bovine adrenocortical cells: Phosphorylation and activation by cAMP-dependent protein kinase
    • DOI 10.1042/0264-6021:3520483
    • Rocchi S, Gaillard I, van OE, Chambaz EM, Vilgrain I. Adrenocorticotrophic hormone stimulates phosphotyrosine phosphatase SHP2 in bovine adrenocortical cells: phosphorylation and activation by cAMP-dependent protein kinase. Biochem J 352: 483-490, 2000. (Pubitemid 32011442)
    • (2000) Biochemical Journal , vol.352 , Issue.2 , pp. 483-490
    • Rocchi, S.1    Gaillard, I.2    Van Obberghen, E.3    Chambaz, E.M.4    Vilgrain, I.5
  • 46
    • 0031914778 scopus 로고    scopus 로고
    • Cytokines in inflammatory bowel disease
    • Rogler G, Andus T. Cytokines in inflammatory bowel disease. World J Surg 22: 382-389, 1998.
    • (1998) World J Surg , vol.22 , pp. 382-389
    • Rogler, G.1    Andus, T.2
  • 48
    • 33748848714 scopus 로고    scopus 로고
    • Interleukin-6 biology is coordinated by membrane-bound and soluble receptors: Role in inflammation and cancer
    • DOI 10.1189/jlb.1105674
    • Rose-John S, Scheller J, Elson G, Jones SA. Interleukin-6 biology is coordinated by membrane-bound and soluble receptors: role in inflammation and cancer. J Leukoc Biol 80: 227-236, 2006. (Pubitemid 44835496)
    • (2006) Journal of Leukocyte Biology , vol.80 , Issue.2 , pp. 227-236
    • Rose-John, S.1    Scheller, J.2    Elson, G.3    Jones, S.A.4
  • 49
    • 24344501250 scopus 로고    scopus 로고
    • Nuclear STAT3 translocation in guinea pig and rat brain endothelium during systemic challenge with lipopolysaccharide and interleukin-6
    • DOI 10.1002/cne.20653
    • Rummel C, Voss T, Matsumura K, Korte S, Gerstberger R, Roth J, Hubschle T. Nuclear STAT3 translocation in guinea pig and rat brain endothelium during systemic challenge with lipopolysaccharide and interleukin- 6. J Comp Neurol 491: 1-14, 2005. (Pubitemid 41254611)
    • (2005) Journal of Comparative Neurology , vol.491 , Issue.1 , pp. 1-14
    • Rummel, C.1    Voss, T.2    Matsumuba, K.3    Korte, S.4    Gerstberger, R.5    Roth, J.6    Hubschle, T.7
  • 51
    • 0033810455 scopus 로고    scopus 로고
    • Differential expression and responsiveness of chemokine receptors (CXCR1-3) by human microvascular endothelial cells umbilical vein endothelial cells
    • Salcedo R, Resau JH, Halverson D, Hudson EA, Dambach M, Powell D, Wasserman K, Oppenheim JJ. Differential expression and responsiveness of chemokine receptors (CXCR1-3) by human microvascular endothelial cells and umbilical vein endothelial cells. FASEB J 14: 2055-2064, 2000. (Pubitemid 30747261)
    • (2000) FASEB Journal , vol.14 , Issue.13 , pp. 2055-2064
    • Salcedo, R.1    Resau, J.H.2    Halverson, D.3    Hudson, E.A.4    Dambach, M.5    Powell, D.6    Wasserman, K.7    Oppenheim, J.J.8
  • 53
    • 33747749486 scopus 로고    scopus 로고
    • Exchange protein activated by cyclic AMP (Epac)-mediated induction of suppressor of cytokine signaling 3 (SOCS-3) in vascular endothelial cells
    • DOI 10.1128/MCB.00207-06
    • Sands WA, Woolson HD, Milne GR, Rutherford C, Palmer TM. Exchange protein activated by cyclic AMP (Epac)-mediated induction of suppressor of cytokine signaling 3 (SOCS-3) in vascular endothelial cells. Mol Cell Biol 26: 6333-6346, 2006. (Pubitemid 44277875)
    • (2006) Molecular and Cellular Biology , vol.26 , Issue.17 , pp. 6333-6346
    • Sands, W.A.1    Woolson, H.D.2    Milne, G.R.3    Rutherford, C.4    Palmer, T.M.5
  • 54
    • 0034724677 scopus 로고    scopus 로고
    • SOCS3 exerts its inhibitory function on interleukin-6 signal transduction through the SHP2 recruitment site of gp130
    • DOI 10.1074/jbc.275.17.12848
    • Schmitz J, Weissenbach M, Haan S, Heinrich PC, Schaper F. SOCS3 exerts its inhibitory function on interleukin-6 signal transduction through the SHP2 recruitment site of gp130. J Biol Chem 275: 12848-12856, 2000. (Pubitemid 30241440)
    • (2000) Journal of Biological Chemistry , vol.275 , Issue.17 , pp. 12848-12856
    • Schmitz, J.1    Weissenbach, M.2    Haan, S.3    Heinrich, P.C.4    Schaper, F.5
  • 55
    • 0030587869 scopus 로고    scopus 로고
    • Synthesis of the CC-Chemokines MIP-1alpha, MIP-1beta, and RANTES Is Associated with a Type 1 Immune Response
    • Schrum S, Probst P, Fleischer B, Zipfel PF. Synthesis of the CC-chemokines MIP-1alpha, MIP-1beta, and RANTES is associated with a type 1 immune response. J Immunol 157: 3598-3604, 1996. (Pubitemid 126449174)
    • (1996) Journal of Immunology , vol.157 , Issue.8 , pp. 3598-3604
    • Schrum, S.1    Probst, P.2    Fleischer, B.3    Zipfel, P.F.4
  • 56
    • 33750982120 scopus 로고    scopus 로고
    • Stattic: A Small-Molecule Inhibitor of STAT3 Activation and Dimerization
    • DOI 10.1016/j.chembiol.2006.09.018, PII S1074552106003784
    • Schust J, Sperl B, Hollis A, Mayer TU, Berg T. Stattic: a small-molecule inhibitor of STAT3 activation and dimerization. Chem Biol 13: 1235-1242, 2006. (Pubitemid 44750735)
    • (2006) Chemistry and Biology , vol.13 , Issue.11 , pp. 1235-1242
    • Schust, J.1    Sperl, B.2    Hollis, A.3    Mayer, T.U.4    Berg, T.5
  • 57
    • 0028931604 scopus 로고
    • Choice of STATs and other substrates specified by modular tyrosine-based motifs in cytokine receptors
    • Stahl N, Farruggella TJ, Boulton TG, Zhong Z, Darnell JE Jr, Yancopoulos GD. Choice of STATs and other substrates specified by modular tyrosine-based motifs in cytokine receptors. Science 267: 1349-1353, 1995.
    • (1995) Science , vol.267 , pp. 1349-1353
    • Stahl, N.1    Farruggella, T.J.2    Boulton, T.G.3    Zhong, Z.4    Darnell Jr., J.E.5    Yancopoulos, G.D.6
  • 59
    • 0034222072 scopus 로고    scopus 로고
    • An investigation into the effect and mechanisms of action of nicotine in inflammatory bowel disease
    • Sykes AP, Brampton C, Klee S, Chander CL, Whelan C, Parsons ME. An investigation into the effect and mechanisms of action of nicotine in inflammatory bowel disease. Inflamm Res 49: 311-319, 2000.
    • (2000) Inflamm Res , vol.49 , pp. 311-319
    • Sykes, A.P.1    Brampton, C.2    Klee, S.3    Chander, C.L.4    Whelan, C.5    Parsons, M.E.6
  • 60
    • 33846817498 scopus 로고    scopus 로고
    • Physiology and immunology of the cholinergic antiinflammatory pathway
    • Tracey KJ. Physiology and immunology of the cholinergic antiinflammatory pathway. J Clin Invest 117: 289-296, 2007.
    • (2007) J Clin Invest , vol.117 , pp. 289-296
    • Tracey, K.J.1
  • 61
    • 0035022488 scopus 로고    scopus 로고
    • Growth factor-stimulated protein synthesis is inhibited by sodium orthovanadate
    • DOI 10.1046/j.1432-1327.2001.02108.x
    • Vinals F, McKenzie FR, Pouyssegur J. Growth factor-stimulated protein synthesis is inhibited by sodium orthovanadate. Eur J Biochem 268: 2308-2314, 2001. (Pubitemid 32417758)
    • (2001) European Journal of Biochemistry , vol.268 , Issue.8 , pp. 2308-2314
    • Vinals, F.1    McKenzie, F.R.2    Pouyssegur, J.3
  • 62
    • 0036435526 scopus 로고    scopus 로고
    • Cerebrospinal fluid and serum protein levels of tumour necrosis factor-alpha (TNF-alpha), interleukin-6 (IL-6) and soluble interleukin-6 receptor (sIL-6R gp80) in multiple sclerosis patients
    • DOI 10.1006/cyto.2002.1984
    • Vladic A, Horvat G, Vukadin S, Sucic Z, Simaga S. Cerebrospinal fluid and serum protein levels of tumour necrosis factor-alpha (TNF-alpha) interleukin-6 (IL-6) and soluble interleukin-6 receptor (sIL-6R gp80) in multiple sclerosis patients. Cytokine 20: 86-89, 2002. (Pubitemid 35373725)
    • (2002) Cytokine , vol.20 , Issue.2 , pp. 86-89
    • Vladic, A.1    Horvat, G.2    Vukadin, S.3    Sucic, Z.4    Simaga, S.5
  • 66
    • 27744438212 scopus 로고    scopus 로고
    • Resveratrol suppresses IL-6- Induced ICAM-1 gene expression in endothelial cells: Effects on the inhibition of STAT3 phosphorylation
    • Wung BS, Hsu MC, Wu CC, Hsieh CW. Resveratrol suppresses IL-6- induced ICAM-1 gene expression in endothelial cells: effects on the inhibition of STAT3 phosphorylation. Life Sci 78: 389-397, 2005.
    • (2005) Life Sci , vol.78 , pp. 389-397
    • Wung, B.S.1    Hsu, M.C.2    Wu, C.C.3    Hsieh, C.W.4
  • 67
    • 21544467565 scopus 로고    scopus 로고
    • Signal transducer and activator of transcription 3alpha and specificity protein 1 interact to upregulate intercellular adhesion molecule-1 in ischemic-reperfused myocardium and vascular endothelium
    • DOI 10.1161/01.ATV.0000168428.96177.24
    • Yang XP, Irani K, Mattagajasingh S, Dipaula A, Khanday F, Ozaki M, Fox-Talbot K, Baldwin WM, III, Becker LC. Signal transducer and activator of transcription 3alpha and specificity protein 1 interact to upregulate intercellular adhesion molecule-1 in ischemic-reperfused myocardium and vascular endothelium. Arterioscler Thromb Vasc Biol 25: 1395-1400, 2005. (Pubitemid 40923358)
    • (2005) Arteriosclerosis, Thrombosis, and Vascular Biology , vol.25 , Issue.7 , pp. 1395-1400
    • Yang, X.P.1    Irani, K.2    Mattagajasingh, S.3    Dipaula, A.4    Khanday, F.5    Ozaki, M.6    Fox-Talbot, K.7    Baldwin III, W.M.8    Becker, L.C.9
  • 69
    • 54449088798 scopus 로고    scopus 로고
    • Nicotinic acetyl-choline receptor expression and regulation in the rat kidney after ischemia-reperfusion injury
    • Yeboah MM, Xue X, Javdan M, Susin M, Metz CN. Nicotinic acetyl-choline receptor expression and regulation in the rat kidney after ischemia-reperfusion injury. Am J Physiol Renal Physiol 295: F654-F661, 2008.
    • (2008) Am J Physiol Renal Physiol , vol.295
    • Yeboah, M.M.1    Xue, X.2    Javdan, M.3    Susin, M.4    Metz, C.N.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.