Proteolysis by the ubiquitin-proteasome system and kidney disease

Journal of the American Society of Nephrology

Volumn 22, Issue 5, 2011, Pages 821-824

  Lecker, Stewart H ^a   Mitch, William E ^b  

^a HARVARD MEDICAL SCHOOL   (United States)

^b BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; CELL SURFACE PROTEIN; GAMMA INTERFERON; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; MUSCLE PROTEIN; PROTEASOME; SOMATOMEDIN C; UBIQUITIN;

AMINO TERMINAL SEQUENCE; ARTICLE; GLUCONEOGENESIS; HYDROLYSIS; KIDNEY DISEASE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN SYNTHESIS;

EID: 79955576880     PISSN: 10466673     EISSN: 15333450     Source Type: Journal    
DOI: 10.1681/ASN.2010090958     Document Type: Article

References (30)

1. Lecker SH, Goldberg AL, Mitch WE: Protein degradation by the ubiquitin-proteasome pathway in normal and disease states. J Am Soc Nephrol 17: 1807-1819, 2006
2. Ingham RJ, Gish G, Pawson T: The Nedd4 family of E3 ubiquitin ligases: Functional diversity within a common modular architecture. Oncogene 23: 1972-1984, 2004
3. Petroski MD, Deshaies RJ: Function and regulation of cullin-RING ubiquitin ligases. Nat Rev Mol Cell Biol 6: 9-20, 2005 (Pubitemid 40064895)
4. Groll M, Bajorek M, Kohler A, Moroder L, Rubin DM, Huber R, Glickman MH, Finley D: A gated channel into the proteasome core particle. Nat Struct Biol 7: 1062-1067, 2000
5. Kisselev AF, Goldberg AL: Proteasome inhibitors: From research tools to drug candidates. Chem Biol 8: 739-758, 2001 (Pubitemid 32752454)
6. Mitch WE, Goldberg AL: Mechanisms of muscle wasting: The role of the ubiquitinproteasome system. N Engl J Med 335: 1897-1905, 1996
7. Meusser B, Hirsch C, Jarosch E, Sommer T: ERAD: The long road to destruction. Nat Cell Biol 7: 766-772, 2005 (Pubitemid 41079045)
8. Rock KL, Gramm C, Rothstein L, Clark K, Stein R, Dick L, Hwang D, Goldberg AL: Inhibitors of the proteasome block the degradation of most cell proteins and the generation of peptides presented on MHC class 1 molecules. Cell 78: 761-771, 1994 (Pubitemid 24294452)
9. Muratani M, Tansey WP: How the ubiquitinproteasome system controls transcription. Nat Rev Mol Cell Biol 4: 192-201, 2003 (Pubitemid 36288041)
10. Hicke L, Dunn R: Regulation of membrane protein transport by ubiquitin and ubiquitinbinding proteins. Annu Rev Cell Dev Biol 19: 141-172, 2003 (Pubitemid 37487346)
11. Gong P, Canaan A, Wang B, Leventhal J, Snyder A, Nair V, Cohen CD, Kretzler M, D'Agati V, Weissman S, Ross MJ: The ubiquitin- like protein FAT10 mediates NF-kappaB activation. J Am Soc Nephrol 21: 316-326, 2010
12. Gai Z, Zhou G, Gui T, Itoh S, Oikawa K, Uetani K, Muragaki Y: Trps1 haploinsufficiency promotes renal fibrosis by increasing Arkadia expression. J Am Soc Nephrol 21: 1468-1476, 2010
13. Kaelin WG Jr: How oxygen makes its presence felt. Genes Dev 16: 1441-1445, 2002
14. Malik B, Price SR, Mitch WE, Yue Q, Eaton DC: Regulation of epithelial sodium channels by the ubiquitin-proteasome proteolytic pathway. Am J Physiol 290: F1285-F1294, 2006 (Pubitemid 43830751)
15. Rock KL, York IA, Goldberg AL: Post-proteasomal antigen processing for major histocompatibility complex class I presentation. Nat Immunol 5: 670-677, 2004 (Pubitemid 39023295)
16. Cascio P, Call M, Petre BM, Walz T, Goldberg AL: Properties of the hybrid form of the 26S proteasome containing both 19S and PA28 complexes. EMBO J 21: 2636-2645, 2002 (Pubitemid 34619379)
17. Lecker SH, Jagoe RT, Gomes M, Baracos V, Bailey JL, Price SR, Mitch WE, Goldberg AL: Multiple types of skeletal muscle atrophy involve a common program of changes in gene expression. FASEB J 18: 39-51, 2004 (Pubitemid 38076464)
18. Bodine SC, Latres E, Baumhueter S, Lai VK, Nunez L, Clark BA, Poueymirou WT, Panaro FJ, Na E, Dharmarajan K, Pan ZQ, Valenzuel DM, DeChiara TM, Stitt TN, Yancopoulos GD, Glass DJ: Identification of ubiquitin ligases required for skeletal muscle atrophy. Science 294: 1704-1708, 2001 (Pubitemid 33104839)
19. Hanai J, Cao P, Tanksale P, Imamura S, Koshimizu E, Zhao J, Kishi S, Yamashita M, Phillips PS, Sukhatme VP, Lecker SH: The muscle-specific ubiquitin ligase atrogin-1/ MAFbx mediates statin-induced muscle toxicity. J Clin Invest 117: 3940-3951, 2007 (Pubitemid 350224103)
20. Hu Z, Wang H, Lee IH, Du J, Mitch WE: Endogenous glucocorticoids and impaired insulin signaling are both required to stimulate muscle wasting under pathophysiological conditions in mice. J Clin Invest 119: 7650-7659, 2009
21. Lee SW, Dai G, Hu Z, Wang X, Du J, Mitch WE: Regulation of muscle protein degradation: coordinated control of apoptotic and ubiquitin-proteasome systems by phosphatidylinositol 3 kinase. J Am Soc Nephrol 15: 1537-1545, 2004 (Pubitemid 38679678)
22. Sandri M, Sandri C, Gilbert A, Skuck C, Calabria E, Picard A, Walsh K, Schiaffino S, Lecker SH, Goldberg AL: Foxo transcription factors induce the atrophy-related ubiquitin ligase atrogin-1 and cause skeletal muscle atrophy. Cell 117: 399-412, 2004 (Pubitemid 38534545)
23. Song Y-H, Li Y, Du J, Mitch WE, Rosenthal N, Delafontaine P: Muscle-specific expression of insulin-like growth factor-1 blocks angiotensin II-induced skeletal muscle wasting. J Clin Invest 115: 451-458, 2005 (Pubitemid 40385487)
24. Zhang L, Du J, Hu Z, Han G, Delafontaine P, Garcia G, Mitch WE: IL-6 and serum amyloid A synergy mediates angiotensin II-induced muscle wasting. J Am Soc Nephrol 20: 604-612, 2009
25. Mitch WE, Medina R, Greiber S, May RC, England BK, Price SR, Bailey JL, Goldberg AL: Metabolic acidosis stimulates muscle protein degradation by activating the ATPdependent pathway involving ubiquitin and proteasomes. J Clin Invest 93: 2127-2133, 1994 (Pubitemid 24143094)
26. Hu J, Du J, Zhang L, Price SR, Klein JD, Wang XH: XIAP reduces muscle proteolysis induced by CKD. J Am Soc Nephrol 21: 1174-1183, 2010
27. Zhang L, Wang XH, Wang H, Du J, Mitch WE: Satellite cell dysfunction and impaired IGF-1 signaling cause CKD-induced muscle atrophy. J Am Soc Nephrol 21: 419-427, 2010
28. Du J, Wang X, Meireles CL, Bailey JL, Debigare R, Zheng B, Price SR, Mitch WE: Activation of caspase 3 is an initial step triggering muscle proteolysis in catabolic conditions. J Clin Invest 113: 115-123, 2004 (Pubitemid 38541638)
29. Workeneh B, Rondon-Berrios H, Zhang L, Hu Z, Ayehu G, Ferrando A, Kopple JD, Wang H, Storer TW, Fournier M, Lee SW, Du J, Mitch WE: Development of a diagnostic method for detecting increased muscle protein degradation in patients with catabolic conditions. J Am Soc Nephrol 17: 3233-3239, 2006 (Pubitemid 44707785)
30. Wang XH, Zhang L, Mitch WE, LeDoux JM, Hu J, Du J: Caspase-3 cleaves specific proteasome subunits in skeletal muscle stimulating proteasome activity. J Biol Chem 285: 3527-3532, 2010