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Volumn 8, Issue 5, 2012, Pages 288-295

The transition of acute to chronic bowel inflammation in spondyloarthritis

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Indexed keywords

CYTOKINE;

EID: 84860560358     PISSN: 17594790     EISSN: 17594804     Source Type: Journal    
DOI: 10.1038/nrrheum.2012.42     Document Type: Review
Times cited : (50)

References (93)
  • 1
    • 79959359494 scopus 로고    scopus 로고
    • Spondyloarthritis
    • Dougados, M. & Baeten, D. Spondyloarthritis. Lancet 377, 2127-2137 (2011)
    • (2011) Lancet , vol.377 , pp. 2127-2137
    • Dougados, M.1    Baeten, D.2
  • 3
    • 84860588640 scopus 로고    scopus 로고
    • Diagnosis and classification in spondyloarthritis: Identifying a chameleon
    • van Tubergen, A. & Weber, U. Diagnosis and classification in spondyloarthritis: Identifying a chameleon. Nat. Rev. Rheumatol. 8, 253-261 (2012)
    • (2012) Nat. Rev. Rheumatol. , vol.8 , pp. 253-261
    • Van Tubergen, A.1    Weber, U.2
  • 4
    • 70349786726 scopus 로고    scopus 로고
    • Treatment of ankylosing spondylitis and extra-Articular manifestations in everyday rheumatology practice
    • Elewaut, D. & Matucci-Cerinic, M. Treatment of ankylosing spondylitis and extra-Articular manifestations in everyday rheumatology practice. Rheumatology (Oxford) 48, 1029-1035 (2009)
    • (2009) Rheumatology (Oxford) , Issue.48 , pp. 1029-1035
    • Elewaut, D.1    Matucci-Cerinic, M.2
  • 5
    • 0034754477 scopus 로고    scopus 로고
    • Etanercept for active Crohn's disease: A randomized, double-blind, placebo-controlled trial
    • Sandborn, W. J. et al. Etanercept for active Crohn's disease: A randomized, double-blind, placebo-controlled trial. Gastroenterology 121, 1088-1094 (2001)
    • (2001) Gastroenterology , vol.121 , pp. 1088-1094
    • Sandborn, W.J.1
  • 6
    • 0033674240 scopus 로고    scopus 로고
    • Spondyloarthropathy is underestimated in inflammatory bowel disease: Prevalence and HLA association
    • De Vlam, K. et al. Spondyloarthropathy is underestimated in inflammatory bowel disease: Prevalence and HLA association. J. Rheumatol. 27, 2860-2865 (2000)
    • (2000) J. Rheumatol. , vol.27 , pp. 2860-2865
    • De Vlam, K.1
  • 7
    • 0028823453 scopus 로고
    • The evolution of spondylarthropathies in relation to gut histology. II. Histological aspects
    • Mielants, H. et al. The evolution of spondylarthropathies in relation to gut histology. II. Histological aspects. J. Rheumatol. 22, 2273-2278 (1995)
    • (1995) J. Rheumatol. , vol.22 , pp. 2273-2278
    • Mielants, H.1
  • 8
    • 0027967690 scopus 로고
    • Clinically silent inflammatory gut lesions in undifferentiated spondyloarthropathies
    • Altomonte, L. et al. Clinically silent inflammatory gut lesions in undifferentiated spondyloarthropathies. Clin. Rheumatol. 13, 565-570 (1994)
    • (1994) Clin. Rheumatol. , vol.13 , pp. 565-570
    • Altomonte, L.1
  • 10
    • 0025202183 scopus 로고
    • Macroscopic and microscopic gut lesions in seronegative spondyloarthropathies
    • Simenon, G., Van Gossum, A., Adler, M., Rickaert, F. & Appelboom, T. Macroscopic and microscopic gut lesions in seronegative spondyloarthropathies. J. Rheumatol. 17, 1491-1494 (1990)
    • (1990) J. Rheumatol. , vol.17 , pp. 1491-1494
    • Simenon, G.1    Van Gossum, A.2    Adler, M.3    Rickaert, F.4    Appelboom, T.5
  • 11
    • 0029878148 scopus 로고    scopus 로고
    • Course of gut inflammation in spondylarthropathies and therapeutic consequences
    • Mielants, H., Veys, E., Cuvelier, C. & De Vos, M. Course of gut inflammation in spondylarthropathies and therapeutic consequences. Baillieres Clin. Rheumatol. 10, 147-164 (1996)
    • (1996) Baillieres Clin. Rheumatol. , Issue.10 , pp. 147-164
    • Mielants, H.1    Veys, E.2    Cuvelier, C.3    De Vos, M.4
  • 12
    • 0028961892 scopus 로고
    • Gut inflammation in psoriatic arthritis: A prospective ileocolonoscopic study
    • Schatteman, L. et al. Gut inflammation in psoriatic arthritis: A prospective ileocolonoscopic study. J. Rheumatol. 22, 680-683 (1995)
    • (1995) J. Rheumatol. , vol.22 , pp. 680-683
    • Schatteman, L.1
  • 13
    • 0027733745 scopus 로고
    • Gut inflammation in children with late onset pauciarticular juvenile chronic arthritis and evolution to adult spondyloarthropathy-A prospective study
    • Mielants, H. et al. Gut inflammation in children with late onset pauciarticular juvenile chronic arthritis and evolution to adult spondyloarthropathy-A prospective study. J. Rheumatol. 20, 1567-1572 (1993)
    • (1993) J. Rheumatol. , vol.20 , pp. 1567-1572
    • Mielants, H.1
  • 14
    • 50149092456 scopus 로고    scopus 로고
    • Joint expedition: Linking gut inflammation to arthritis
    • Jacques, P. & Elewaut, D. Joint expedition: Linking gut inflammation to arthritis. Mucosal Immunol. 1, 364-371 (2008)
    • (2008) Mucosal Immunol. , Issue.1 , pp. 364-371
    • Jacques, P.1    Elewaut, D.2
  • 15
    • 0028789392 scopus 로고
    • The evolution of spondyloarthropathies in relation to gut histology. III. Relation between gut and joint
    • Mielants, H. et al. The evolution of spondyloarthropathies in relation to gut histology. III. Relation between gut and joint. J. Rheumatol. 22, 2279-2284 (1995)
    • (1995) J. Rheumatol. , vol.22 , pp. 2279-2284
    • Mielants, H.1
  • 16
    • 0023157222 scopus 로고
    • Histopathology of intestinal inflammation related to reactive arthritis
    • Cuvelier, C. et al. Histopathology of intestinal inflammation related to reactive arthritis. Gut 28, 394-401 (1987)
    • (1987) Gut , vol.28 , pp. 394-401
    • Cuvelier, C.1
  • 17
    • 0026327181 scopus 로고
    • Gut inflammation in the spondyloarthropathies: Clinical, radiologic, biologic and genetic features in relation to the type of histology. A prospective study
    • Mielants, H. et al. Gut inflammation in the spondyloarthropathies: Clinical, radiologic, biologic and genetic features in relation to the type of histology. A prospective study. J. Rheumatol. 18, 1542-1551 (1991)
    • (1991) J. Rheumatol. , vol.18 , pp. 1542-1551
    • Mielants, H.1
  • 18
    • 84860585350 scopus 로고    scopus 로고
    • Genetics of spondyloarthritis-beyond the MHC
    • Reveille, J. D. Genetics of spondyloarthritis-beyond the MHC. Nat. Rev. Rheumatol. 8, 296-304 (2012)
    • (2012) Nat. Rev. Rheumatol. , vol.8 , pp. 296-304
    • Reveille, J.D.1
  • 19
    • 34547742519 scopus 로고    scopus 로고
    • A common genetic background for inflammatory bowel disease and ankylosing spondylitis: A genealogic study in Iceland
    • Thjodleifsson, B., Geirsson, A. J., Björnsson, S. & Bjarnason, I. A common genetic background for inflammatory bowel disease and ankylosing spondylitis: A genealogic study in Iceland. Arthritis Rheum. 56, 2633-2639 (2007)
    • (2007) Arthritis Rheum. , Issue.56 , pp. 2633-2639
    • Thjodleifsson, B.1    Geirsson, A.J.2    Björnsson, S.3    Bjarnason, I.4
  • 20
    • 75749085686 scopus 로고    scopus 로고
    • Genome-wide association study of ankylosing spondylitis identifies non-MHC susceptibility loci
    • Reveille, J. D. et al. Genome-wide association study of ankylosing spondylitis identifies non-MHC susceptibility loci. Nat. Genet. 42, 123-127 (2010)
    • (2010) Nat. Genet. , vol.42 , pp. 123-127
    • Reveille, J.D.1
  • 21
    • 70949107842 scopus 로고    scopus 로고
    • Inflammatory bowel disease
    • Abraham, C. & Cho, J. Inflammatory bowel disease. N. Engl. J. Med. 361, 2066-2078 (2009)
    • (2009) N. Engl. J. Med. , vol.361 , pp. 2066-2078
    • Abraham, C.1    Cho, J.2
  • 22
    • 79955566359 scopus 로고    scopus 로고
    • Recent insights into the genetics of inflammatory bowel disease
    • Cho, J. H. & Brant, S. R. Recent insights into the genetics of inflammatory bowel disease. Gastroenterology 140, 1704-1721 (2011)
    • (2011) Gastroenterology , vol.140 , pp. 1704-1721
    • Cho, J.H.1    Brant, S.R.2
  • 23
    • 33845340501 scopus 로고    scopus 로고
    • A genome-wide association study identifies IL23R as an inflammatory bowel disease gene
    • Duerr, R. H. et al. A genome-wide association study identifies IL23R as an inflammatory bowel disease gene. Science 314, 1461-1463 (2006)
    • (2006) Science , vol.314 , pp. 1461-1463
    • Duerr, R.H.1
  • 24
    • 35748981184 scopus 로고    scopus 로고
    • Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants
    • Burton, P. R. et al. Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants. Nat. Genet. 39, 1329-1337 (2007)
    • (2007) Nat. Genet. , vol.39 , pp. 1329-1337
    • Burton, P.R.1
  • 25
    • 78649489009 scopus 로고    scopus 로고
    • Genome-wide meta-Analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci
    • Franke, A. et al. Genome-wide meta-Analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci. Nat. Genet. 42, 1118-1125 (2010)
    • (2010) Nat. Genet. , vol.42 , pp. 1118-1125
    • Franke, A.1
  • 26
    • 78049347495 scopus 로고    scopus 로고
    • A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA C and ERAP1
    • Strange, A. et al. A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA C and ERAP1. Nat. Genet. 42, 985-990 (2010)
    • (2010) Nat. Genet. , vol.42 , pp. 985-990
    • Strange, A.1
  • 27
    • 33645089946 scopus 로고    scopus 로고
    • In vivo role of ER associated peptidase activity in tailoring peptides for presentation by MHC class Ia and class Ib molecules
    • Yan, J. B. et al. In vivo role of ER associated peptidase activity in tailoring peptides for presentation by MHC class Ia and class Ib molecules. J. Exp. Med. 203, 647-659 (2006)
    • (2006) J. Exp. Med. , vol.203 , pp. 647-659
    • Yan, J.B.1
  • 28
    • 0036679366 scopus 로고    scopus 로고
    • Identification of ARTS 1 as a novel TNFR1-binding protein that promotes TNFR1 ectodomain shedding
    • Cui, X. L. et al. Identification of ARTS 1 as a novel TNFR1-binding protein that promotes TNFR1 ectodomain shedding. J. Clin. Invest. 110, 515-526 (2002)
    • (2002) J. Clin. Invest. , vol.110 , pp. 515-526
    • Cui, X.L.1
  • 29
    • 79953004299 scopus 로고    scopus 로고
    • The genetic basis of spondyloarthritis
    • Reveille, J. D. The genetic basis of spondyloarthritis. Ann. Rheum. Dis. 70 (Suppl. 1), i44-i50 (2011)
    • (2011) Ann. Rheum. Dis. , vol.70 , Issue.SUPPL. 1
    • Reveille, J.D.1
  • 30
    • 79960899377 scopus 로고    scopus 로고
    • Interaction between ERAP1 and HLA B27 in ankylosing spondylitis implicates peptide handling in the mechanism for HLA B27 in disease susceptibility
    • Evans, D. M. et al. Interaction between ERAP1 and HLA B27 in ankylosing spondylitis implicates peptide handling in the mechanism for HLA B27 in disease susceptibility. Nat. Genet. 43, 761-767 (2011)
    • (2011) Nat. Genet. , vol.43 , pp. 761-767
    • Evans, D.M.1
  • 31
    • 78650711124 scopus 로고    scopus 로고
    • Association of variants at 1q32 and STAT3 with ankylosing spondylitis suggests genetic overlap with Crohn's disease
    • Danoy, P. et al. Association of variants at 1q32 and STAT3 with ankylosing spondylitis suggests genetic overlap with Crohn's disease. PLoS Genet. 6, e1001195 (2010)
    • (2010) Plos Genet. , vol.6
    • Danoy, P.1
  • 32
    • 84857715883 scopus 로고    scopus 로고
    • Interleukin 17A blockade with secukinumab reduces spinal inflammation in patients with ankylosing spondylitis as early as week 6, as detected by magnetic resonance imaging [abstract]
    • Baraliakos, X. et al. Interleukin 17A blockade with secukinumab reduces spinal inflammation in patients with ankylosing spondylitis as early as week 6, as detected by magnetic resonance imaging [abstract]. Arthritis Rheum. 63, 2486D (2011)
    • (2011) Arthritis Rheum. , vol.63
    • Baraliakos, X.1
  • 33
    • 79958270128 scopus 로고    scopus 로고
    • Inhibition of IL 17A by secukinumab is ineffective for Crohn's disease (CD)
    • Hueber, W. et al. Inhibition of IL 17A by secukinumab is ineffective for Crohn's disease (CD). J. Crohns Colitis 5, S6-S7 (2011)
    • (2011) J. Crohns Colitis , vol.5
    • Hueber, W.1
  • 34
    • 43449111187 scopus 로고    scopus 로고
    • Efficacy and safety of ustekinumab, a human interleukin 12/23 monoclonal antibody, in patients with psoriasis: 76-week results from a randomised, double-blind, placebo-controlled trial (phoenix 1)
    • Leonardi, C. L. et al. Efficacy and safety of ustekinumab, a human interleukin 12/23 monoclonal antibody, in patients with psoriasis: 76-week results from a randomised, double-blind, placebo-controlled trial (PHOENIX 1). Lancet 371, 1665-1674 (2008)
    • (2008) Lancet , vol.371 , pp. 1665-1674
    • Leonardi, C.L.1
  • 35
    • 60249084148 scopus 로고    scopus 로고
    • Ustekinumab, a human interleukin 12/23 monoclonal antibody, for psoriatic arthritis: Randomised, double-blind, placebo-controlled, crossover trial
    • Gottlieb, A. et al. Ustekinumab, a human interleukin 12/23 monoclonal antibody, for psoriatic arthritis: Randomised, double-blind, placebo-controlled, crossover trial. Lancet 373, 633-640 (2009)
    • (2009) Lancet , vol.373 , pp. 633-640
    • Gottlieb, A.1
  • 36
    • 53049091561 scopus 로고    scopus 로고
    • A randomized trial of Ustekinumab, a human interleukin 12/23 monoclonal antibody, in patients with moderate to severe Crohn's disease
    • Sandborn, W. J. et al. A randomized trial of Ustekinumab, a human interleukin 12/23 monoclonal antibody, in patients with moderate to severe Crohn's disease. Gastroenterology 135, 1130-1141 (2008)
    • (2008) Gastroenterology , vol.135 , pp. 1130-1141
    • Sandborn, W.J.1
  • 37
    • 84860572793 scopus 로고    scopus 로고
    • Developments in therapy for spondyloarthritis
    • Sieper, J. Developments in therapy for spondyloarthritis. Nat. Rev. Rheumatol. 8, 280-287 (2012)
    • (2012) Nat. Rev. Rheumatol. , vol.8 , pp. 280-287
    • Sieper, J.1
  • 38
    • 77955270391 scopus 로고    scopus 로고
    • Analysis of JAK2 and STAT3 polymorphisms in patients with ankylosing spondylitis in Chinese Han population
    • Chen, C., Zhang, X. & Wang, Y. Analysis of JAK2 and STAT3 polymorphisms in patients with ankylosing spondylitis in Chinese Han population. Clin. Immunol. 136, 442-446 (2010)
    • (2010) Clin. Immunol. , vol.136 , pp. 442-446
    • Chen, C.1    Zhang, X.2    Wang, Y.3
  • 39
    • 42749096082 scopus 로고    scopus 로고
    • Genetic analysis of innate immunity in Crohn's disease and ulcerative colitis identifies two susceptibility loci harboring CARD9 and IL18RAP
    • Zhernakova, A. et al. Genetic analysis of innate immunity in Crohn's disease and ulcerative colitis identifies two susceptibility loci harboring CARD9 and IL18RAP. Am. J. Hum. Genet. 82, 1202-1210 (2008)
    • (2008) Am. J. Hum. Genet. , vol.82 , pp. 1202-1210
    • Zhernakova, A.1
  • 40
    • 77956344915 scopus 로고    scopus 로고
    • Elucidating the chromosome 9 association with AS; CARD9 is a candidate gene
    • Pointon, J. J. et al. Elucidating the chromosome 9 association with AS; CARD9 is a candidate gene. Genes Immun. 11, 490-496 (2010)
    • (2010) Genes Immun. , vol.11 , pp. 490-496
    • Pointon, J.J.1
  • 41
    • 52949091918 scopus 로고    scopus 로고
    • Loci on 20q13 and 21q22 are associated with pediatric-onset inflammatory bowel disease
    • Kugathasan, S. et al. Loci on 20q13 and 21q22 are associated with pediatric-onset inflammatory bowel disease. Nat. Genet. 40, 1211-1215 (2008)
    • (2008) Nat. Genet. , vol.40 , pp. 1211-1215
    • Kugathasan, S.1
  • 42
    • 21144450476 scopus 로고    scopus 로고
    • CARD15 gene polymorphisms in patients with spondyloarthropathies identify a specific phenotype previously related to Crohn's disease
    • Laukens, D. et al. CARD15 gene polymorphisms in patients with spondyloarthropathies identify a specific phenotype previously related to Crohn's disease. Ann. Rheum. Dis. 64, 930-935 (2005)
    • (2005) Ann. Rheum. Dis. , vol.64 , pp. 930-935
    • Laukens, D.1
  • 44
    • 0037404927 scopus 로고    scopus 로고
    • Anti-Saccharomyces cerevisiae IgA antibodies are raised in ankylosing spondylitis and undifferentiated spondyloarthropathy
    • Hoffman, I. E. et al. Anti-Saccharomyces cerevisiae IgA antibodies are raised in ankylosing spondylitis and undifferentiated spondyloarthropathy. Ann. Rheum. Dis. 62, 455-459 (2003)
    • (2003) Ann. Rheum. Dis. , vol.62 , pp. 455-459
    • Hoffman, I.E.1
  • 45
    • 78149267009 scopus 로고    scopus 로고
    • Zpanca ASCA and OmpC antibodies in patients with ankylosing spondylitis without inflammatory bowel disease
    • De Vries, M. et al. pANCA, ASCA, and OmpC antibodies in patients with ankylosing spondylitis without inflammatory bowel disease. J. Rheumatol. 37, 2340-2344 (2010)
    • (2010) J. Rheumatol. , vol.37 , pp. 2340-2344
    • De Vries, M.1
  • 46
    • 66649100476 scopus 로고    scopus 로고
    • Monitoring disease activity by stool analyses: From occult blood to molecular markers of intestinal inflammation and damage
    • Foell, D., Wittkowski, H. & Roth, J. Monitoring disease activity by stool analyses: From occult blood to molecular markers of intestinal inflammation and damage. Gut 58, 859-868 (2009)
    • (2009) Gut , vol.58 , pp. 859-868
    • Foell, D.1    Wittkowski, H.2    Roth, J.3
  • 47
    • 77952466960 scopus 로고    scopus 로고
    • Inflammatory bowel disease serologies in ankylosing spondylitis patients: A pilot study
    • Mundwiler, M. L. et al. Inflammatory bowel disease serologies in ankylosing spondylitis patients: A pilot study. Arthritis Res. Ther. 11, R177 (2009)
    • (2009) Arthritis Res. Ther. , vol.11
    • Mundwiler, M.L.1
  • 49
    • 10744225248 scopus 로고    scopus 로고
    • Subclinical intestinal inflammation and sacroiliac changes in relatives of patients with ankylosing spondylitis
    • Bjarnason, I. et al. Subclinical intestinal inflammation and sacroiliac changes in relatives of patients with ankylosing spondylitis. Gastroenterology 125, 1598-1605 (2003)
    • (2003) Gastroenterology , vol.125 , pp. 1598-1605
    • Bjarnason, I.1
  • 50
    • 33745775434 scopus 로고    scopus 로고
    • Mechanisms of disease: Pathogenesis of Crohn's disease and ulcerative colitis
    • Sartor, R. B. Mechanisms of disease: Pathogenesis of Crohn's disease and ulcerative colitis. Nat. Clin. Pract. Gastroenterol. Hepatol. 3, 390-407 (2006)
    • (2006) Nat. Clin. Pract. Gastroenterol. Hepatol. , vol.3 , pp. 390-407
    • Sartor, R.B.1
  • 51
    • 2342442430 scopus 로고    scopus 로고
    • Reduction in diversity of the colonic mucosa associated bacterial microflora in patients with active inflammatory bowel disease
    • Ott, S. J. et al. Reduction in diversity of the colonic mucosa associated bacterial microflora in patients with active inflammatory bowel disease. Gut 53, 685-693 (2004)
    • (2004) Gut , vol.53 , pp. 685-693
    • Ott, S.J.1
  • 52
    • 35348857386 scopus 로고    scopus 로고
    • Molecular-phylogenetic characterization of microbial community imbalances in human inflammatory bowel diseases
    • Frank, D. N. et al. Molecular-phylogenetic characterization of microbial community imbalances in human inflammatory bowel diseases. Proc. Natl Acad. Sci. USA 104, 13780-13785 (2007)
    • (2007) Proc. Natl Acad. Sci. USA , vol.104 , pp. 13780-13785
    • Frank, D.N.1
  • 53
    • 77957603468 scopus 로고    scopus 로고
    • The role of bacteria in the pathogenesis of inflammatory bowel disease
    • Friswell, M., Campbell, B. & Rhodes, J. The role of bacteria in the pathogenesis of inflammatory bowel disease. Gut Liver 4, 295-306 (2010)
    • (2010) Gut Liver , vol.4 , pp. 295-306
    • Friswell, M.1    Campbell, B.2    Rhodes, J.3
  • 54
    • 78649622569 scopus 로고    scopus 로고
    • Dysbiosis of fecal microbiota in Crohn's disease patients as revealed by a custom phylogenetic microarray
    • Kang, S. et al. Dysbiosis of fecal microbiota in Crohn's disease patients as revealed by a custom phylogenetic microarray. Inflamm. Bowel Dis. 16, 2034-2042 (2010)
    • (2010) Inflamm. Bowel Dis. , vol.16 , pp. 2034-2042
    • Kang, S.1
  • 55
    • 79958261709 scopus 로고    scopus 로고
    • The bowel microbiota and inflammatory bowel diseases
    • Tannock, G. W. The bowel microbiota and inflammatory bowel diseases. Int. J. Inflam. 2010, 954051 (2010)
    • (2010) Int. J. Inflam. , vol.2010 , pp. 954051
    • Tannock, G.W.1
  • 56
    • 0031709152 scopus 로고    scopus 로고
    • Development and maintenance of the gut-Associated lymphoid tissue (GALT): The roles of enteric bacteria and viruses
    • Cebra, J. J., Periwal, S. B., Lee, G., Lee, F. & Shroff, K. E. Development and maintenance of the gut-Associated lymphoid tissue (GALT): The roles of enteric bacteria and viruses. Dev. Immunol. 6, 13-18 (1998)
    • (1998) Dev. Immunol. , vol.6 , pp. 13-18
    • Cebra, J.J.1    Periwal, S.B.2    Lee, G.3    Lee, F.4    Shroff, K.E.5
  • 57
    • 0015807870 scopus 로고
    • Factors affecting the lymphoid cells in the small intestinal epithelium of the mouse
    • Glaister, J. R. Factors affecting the lymphoid cells in the small intestinal epithelium of the mouse. Int. Arch. Allergy Appl. Immunol. 45, 719-730 (1973)
    • (1973) Int. Arch. Allergy Appl. Immunol. , vol.45 , pp. 719-730
    • Glaister, J.R.1
  • 58
    • 0028003794 scopus 로고
    • The germfree state prevents development of gut and joint inflammatory disease in HLA B27 transgenic rats
    • Taurog, J. D. et al. The germfree state prevents development of gut and joint inflammatory disease in HLA B27 transgenic rats. J. Exp. Med. 180, 2359-2364 (1994)
    • (1994) J. Exp. Med. , vol.180 , pp. 2359-2364
    • Taurog, J.D.1
  • 59
    • 80155130269 scopus 로고    scopus 로고
    • Time for a gut check: Evidence for the hypothesis that HLA-B27 predisposes to ankylosing spondylitis by altering the microbiome
    • Rosenbaum, J. T. & Davey, M. P. Time for a gut check: Evidence for the hypothesis that HLA-B27 predisposes to ankylosing spondylitis by altering the microbiome. Arthritis Rheum. 63, 3195-3198 (2011)
    • (2011) Arthritis Rheum. , Issue.63 , pp. 3195-3198
    • Rosenbaum, J.T.1    Davey, M.P.2
  • 60
    • 0025234494 scopus 로고
    • Uilt by association: HLA B27 and ankylosing spondylitis
    • Benjamin, R. & Parham, P. Guilt by association: HLA B27 and ankylosing spondylitis. Immunol. Today 11, 137-142 (1990)
    • (1990) Immunol. Today , vol.11 , pp. 137-142
    • Benjamin, R.1    Parham, P.2
  • 61
    • 0036846149 scopus 로고    scopus 로고
    • Cell-surface expression and immune receptor recognition of HLA B27 homodimers
    • Kollnberger, S. et al. Cell-surface expression and immune receptor recognition of HLA B27 homodimers. Arthritis Rheum. 46, 2972-2982 (2002)
    • (2002) Arthritis Rheum. , vol.46 , pp. 2972-2982
    • Kollnberger, S.1
  • 62
    • 33748861096 scopus 로고    scopus 로고
    • Paneth cell antimicrobial peptides: Topographical distribution and quantification in human gastrointestinal tissues
    • Wehkamp, J. et al. Paneth cell antimicrobial peptides: Topographical distribution and quantification in human gastrointestinal tissues. FEBS Lett. 580, 5344-5350 (2006)
    • (2006) FEBS Lett. , vol.580 , pp. 5344-5350
    • Wehkamp, J.1
  • 63
    • 29144483937 scopus 로고    scopus 로고
    • Reduced Paneth cell a-defensins in ileal Crohn's disease
    • Wehkamp, J. et al. Reduced Paneth cell a-defensins in ileal Crohn's disease. Proc. Natl Acad. Sci. USA 102, 18129-18234 (2005)
    • (2005) Proc. Natl Acad. Sci. USA , vol.102 , pp. 18129-18234
    • Wehkamp, J.1
  • 64
    • 78649354905 scopus 로고    scopus 로고
    • Over-expression of paneth cell-derived anti-microbial peptides in the gut of patients with ankylosing spondylitis and subclinical intestinal inflammation
    • Ciccia, F. et al. Over-expression of paneth cell-derived anti-microbial peptides in the gut of patients with ankylosing spondylitis and subclinical intestinal inflammation. Rheumatology (Oxford) 49, 2076-2083 (2010)
    • (2010) Rheumatology (Oxford) , vol.49 , pp. 2076-2083
    • Ciccia, F.1
  • 65
    • 65249152431 scopus 로고    scopus 로고
    • Overexpression of interleukin 23, but not interleukin 17, as an immunologic signature of subclinical intestinal inflammation in ankylosing spondylitis
    • Ciccia, F. et al. Overexpression of interleukin 23, but not interleukin 17, as an immunologic signature of subclinical intestinal inflammation in ankylosing spondylitis. Arthritis Rheum. 60, 955-965 (2009)
    • (2009) Arthritis Rheum. , vol.60 , pp. 955-965
    • Ciccia, F.1
  • 66
    • 62749198174 scopus 로고    scopus 로고
    • Atural killer T cells and autoimmune disease
    • Wu, L. & Van Kaer, L. Natural killer T cells and autoimmune disease. Curr. Mol. Med. 9, 4-14 (2009)
    • (2009) Curr. Mol. Med. , Issue.9 , pp. 4-14
    • Wu, L.1    Van Kaer, L.2
  • 67
    • 74049164847 scopus 로고    scopus 로고
    • Egulatory T cells exert checks and balances on self tolerance and autoimmunity
    • Wing, K. & Sakaguchi, S. Regulatory T cells exert checks and balances on self tolerance and autoimmunity. Nat. Immunol. 11, 7-13 (2010)
    • (2010) Nat. Immunol. , vol.11 , pp. 7-13
    • Wing, K.1    Sakaguchi, S.2
  • 68
    • 16844362608 scopus 로고    scopus 로고
    • Mechanisms of suppression by suppressor T cells
    • von Boehmer, H. Mechanisms of suppression by suppressor T cells. Nat. Immunol. 6, 338-344 (2005)
    • (2005) Nat. Immunol. , vol.6 , pp. 338-344
    • Von Boehmer, H.1
  • 69
    • 34249103661 scopus 로고    scopus 로고
    • The unique role of natural killer T cells in the response to microorganisms
    • Tupin E, Kinjo Y, Kronenberg M. The unique role of natural killer T cells in the response to microorganisms. Nat. Rev. Microbiol. 5, 405-417 (2007)
    • (2007) Nat. Rev. Microbiol. , vol.5 , pp. 405-417
    • Tupin, E.1    Kinjo, Y.2    Kronenberg, M.3
  • 70
    • 20444434616 scopus 로고    scopus 로고
    • 4+ CD25high T cells in inflammatory bowel disease
    • 4+ CD25high T cells in inflammatory bowel disease. Gastroenterology 128, 1868-1878 (2005)
    • (2005) Gastroenterology , vol.128 , pp. 1868-1878
    • Maul, J.1
  • 71
    • 36249014365 scopus 로고    scopus 로고
    • 4+ regulatory T cells in Crohn's disease
    • 4+ regulatory T cells in Crohn's disease. Clin. Immunol. 125, 281-290 (2007)
    • (2007) Clin. Immunol. , vol.125 , pp. 281-290
    • Saruta, M.1
  • 72
    • 78650072547 scopus 로고    scopus 로고
    • 4+CD25high TREG cells in patients with ankylosing spondylitis: A putative role for interleukin 10 in preventing intestinal TH17 response
    • 4+CD25high TREG cells in patients with ankylosing spondylitis: A putative role for interleukin 10 in preventing intestinal TH17 response. Arthritis Rheum. 62, 3625-3634 (2010)
    • (2010) Arthritis Rheum. , vol.62 , pp. 3625-3634
    • Ciccia, F.1
  • 73
    • 78650080500 scopus 로고    scopus 로고
    • 3+ regulatory T cells in inflammatory bowel diseases
    • 3+ regulatory T cells in inflammatory bowel diseases. Inflamm. Bowel Dis. 17, 160-170 (2011)
    • (2011) Inflamm. Bowel Dis. , vol.17 , pp. 160-170
    • Boschetti, G.1
  • 74
    • 78249240373 scopus 로고    scopus 로고
    • Peripheral regulatory T cells and serum transforming growth factor-β Relationship with clinical response to infliximab in Crohn's disease
    • Di Sabatino, A. et al. Peripheral regulatory T cells and serum transforming growth factor-β: Relationship with clinical response to infliximab in Crohn's disease. Inflamm. Bowel Dis. 16, 1891-1897 (2010)
    • (2010) Inflamm. Bowel Dis. , vol.16 , pp. 1891-1897
    • Di Sabatino, A.1
  • 76
    • 80155126034 scopus 로고    scopus 로고
    • 3+ T cells in spondyloarthritis
    • 3+ T cells in spondyloarthritis. J. Rheumatol. 38, 2445-2451 (2011)
    • (2011) J. Rheumatol. , vol.38 , pp. 2445-2451
    • Appel, H.1
  • 77
    • 77950522748 scopus 로고    scopus 로고
    • Invariant natural killer T cells are natural regulators of murine spondylarthritis
    • Jacques, P. et al. Invariant natural killer T cells are natural regulators of murine spondylarthritis. Arthritis Rheum. 62, 988-999 (2010)
    • (2010) Arthritis Rheum. , vol.62 , pp. 988-999
    • Jacques, P.1
  • 78
    • 0033637389 scopus 로고    scopus 로고
    • Comparative study of the synovial histology in rheumatoid arthritis, spondyloarthropathy, and osteoarthritis: Influence of disease duration and activity
    • Baeten, D. et al. Comparative study of the synovial histology in rheumatoid arthritis, spondyloarthropathy, and osteoarthritis: Influence of disease duration and activity. Ann. Rheum. Dis. 59, 945-953 (2000)
    • (2000) Ann. Rheum. Dis. , vol.59 , pp. 945-953
    • Baeten, D.1
  • 79
    • 0034941556 scopus 로고    scopus 로고
    • Impaired TH1 cytokine production in spondyloarthropathy is restored by anti-TNFa
    • Baeten, D. et al. Impaired TH1 cytokine production in spondyloarthropathy is restored by anti-TNFa. Ann. Rheum. Dis. 60, 750-755 (2001)
    • (2001) Ann. Rheum. Dis. , vol.60 , pp. 750-755
    • Baeten, D.1
  • 80
    • 0034078762 scopus 로고    scopus 로고
    • Differential TH1/TH2 cytokine patterns in chronic arthritis: Interferon ? is highly expressed in synovium of rheumatoid arthritis compared with seronegative spondyloarthropathies
    • Cañete, J. D. et al. Differential TH1/TH2 cytokine patterns in chronic arthritis: Interferon ? is highly expressed in synovium of rheumatoid arthritis compared with seronegative spondyloarthropathies. Ann. Rheum. Dis. 59, 263-268 (2000)
    • (2000) Ann. Rheum. Dis. , vol.59 , pp. 263-268
    • Cañete, J.D.1
  • 81
    • 0036187210 scopus 로고    scopus 로고
    • Macrophages expressing the scavenger receptor CD163: A link between immune alterations of the gut and synovial inflammation in spondyloarthropathy
    • Baeten, D. et al. Macrophages expressing the scavenger receptor CD163: A link between immune alterations of the gut and synovial inflammation in spondyloarthropathy. J. Pathol. 196, 343-350 (2002)
    • (2002) J. Pathol. , vol.196 , pp. 343-350
    • Baeten, D.1
  • 82
    • 77949444874 scopus 로고    scopus 로고
    • Systemic levels of IL-23 are strongly associated with disease activity in rheumatoid arthritis but not spondyloarthritis
    • Melis, L. et al. Systemic levels of IL-23 are strongly associated with disease activity in rheumatoid arthritis but not spondyloarthritis. Ann. Rheum. Dis. 69, 618-623 (2010)
    • (2010) Ann. Rheum. Dis. , vol.69 , pp. 618-623
    • Melis, L.1
  • 83
    • 77949671504 scopus 로고    scopus 로고
    • Rogress in spondyloarthritis. Immunopathogenesis of spondyloarthritis: Which cells drive disease
    • Melis, L. & Elewaut, D. Progress in spondyloarthritis. Immunopathogenesis of spondyloarthritis: Which cells drive disease? Arthritis Res. Ther. 11, 233 (2009)
    • (2009) Arthritis Res. Ther. , Issue.11 , pp. 233
    • Melis, L.1    Elewaut, D.2
  • 84
    • 42449146934 scopus 로고    scopus 로고
    • Association of interleukin-23 receptor variants with ankylosing spondylitis
    • Rahman P. et al. Association of interleukin-23 receptor variants with ankylosing spondylitis. Arthritis Rheum. 58, 1020-1025 (2008)
    • (2008) Arthritis Rheum. , vol.58 , pp. 1020-1025
    • Rahman, P.1
  • 85
    • 69449086287 scopus 로고    scopus 로고
    • HLA B27 misfolding and the unfolded protein response augment interleukin 23 production and are associated with TH17 activation in transgenic rats
    • DeLay, M. L. et al. HLA B27 misfolding and the unfolded protein response augment interleukin 23 production and are associated with TH17 activation in transgenic rats. Arthritis Rheum. 60, 2633-2643 (2009)
    • (2009) Arthritis Rheum. , vol.60 , pp. 2633-2643
    • DeLay, M.L.1
  • 86
    • 79959207913 scopus 로고    scopus 로고
    • Analysis of IL 17+ cells in facet joints of patients with spondyloarthritis suggests that the innate immune pathway might be of greater relevance than the TH17-mediated adaptive immune response
    • Appel, H. et al. Analysis of IL 17+ cells in facet joints of patients with spondyloarthritis suggests that the innate immune pathway might be of greater relevance than the TH17-mediated adaptive immune response. Arthritis Res. Ther. 13, R95 (2011)
    • (2011) Arthritis Res. Ther. , vol.13
    • Appel, H.1
  • 87
    • 39549089300 scopus 로고    scopus 로고
    • Mesenchymal cell targeting by TNF as a common pathogenic principle in chronic inflammatory joint and intestinal diseases
    • Armaka, M. et al. Mesenchymal cell targeting by TNF as a common pathogenic principle in chronic inflammatory joint and intestinal diseases. J. Exp. Med. 205, 331-337 (2008)
    • (2008) J. Exp. Med. , vol.205 , pp. 331-337
    • Armaka, M.1
  • 88
    • 79955113861 scopus 로고    scopus 로고
    • Intestinal epithelial cells as producers but not targets of chronic TNF suffice to cause murine Crohn-like pathology
    • Roulis, M., Armaka, M., Manoloukos, M., Apostolaki, M. & Kollias, G. Intestinal epithelial cells as producers but not targets of chronic TNF suffice to cause murine Crohn-like pathology. Proc. Natl Acad. Sci. USA 108, 5396-5401 (2011)
    • (2011) Proc. Natl Acad. Sci. USA , vol.108 , pp. 5396-5401
    • Roulis, M.1    Armaka, M.2    Manoloukos, M.3    Apostolaki, M.4    Kollias, G.5
  • 89
    • 38849141814 scopus 로고    scopus 로고
    • IL 22 ameliorates intestinal inflammation in a mouse model of ulcerative colitis
    • Sugimoto K. et al. IL 22 ameliorates intestinal inflammation in a mouse model of ulcerative colitis. J. Clin. Invest. 118, 534-544 (2008)
    • (2008) J. Clin. Invest. , vol.118 , pp. 534-544
    • Sugimoto, K.1
  • 90
    • 34247556456 scopus 로고    scopus 로고
    • IL 22 induces lipopolysaccharide-binding protein in hepatocytes: A potential systemic role of IL 22 in Crohn's disease
    • Wolk K. et al. IL 22 induces lipopolysaccharide-binding protein in hepatocytes: A potential systemic role of IL 22 in Crohn's disease. J. Immunol. 178, 5973-5981 (2007)
    • (2007) J. Immunol. , vol.178 , pp. 5973-5981
    • Wolk, K.1
  • 91
    • 59649099774 scopus 로고    scopus 로고
    • A human natural killer cell subset provides an innate source of IL 22 for mucosal immunity
    • Cella, M. et al. A human natural killer cell subset provides an innate source of IL 22 for mucosal immunity. Nature 457, 722-725 (2009)
    • (2009) Nature , vol.457 , pp. 722-725
    • Cella, M.1
  • 92
    • 85027927719 scopus 로고    scopus 로고
    • Enterotypes of the human gut microbiome
    • Arumugam, M. et al. Enterotypes of the human gut microbiome. Nature 473, 174-180 (2011)
    • (2011) Nature , vol.473 , pp. 174-180
    • Arumugam, M.1
  • 93
    • 80053568996 scopus 로고    scopus 로고
    • Subclinical gut inflammation in spondyloarthritis is associated with a pro-Angiogenic intestinal mucosal phenotype
    • Hindryckx, P. et al. Subclinical gut inflammation in spondyloarthritis is associated with a pro-Angiogenic intestinal mucosal phenotype. Ann. Rheum. Dis. 70, 2044-2048 (2011)
    • (2011) Ann. Rheum. Dis. , vol.70 , pp. 2044-2048
    • Hindryckx, P.1


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