-
1
-
-
0034641980
-
Apoptosis in development
-
Meier P, Finch A, Evan G. Apoptosis in development. Nature 2000;407: 796-801.
-
(2000)
Nature
, vol.407
, pp. 796-801
-
-
Meier, P.1
Finch, A.2
Evan, G.3
-
2
-
-
0028943734
-
Apoptosis in the pathogenesis and treatment of disease
-
Thompson CB. Apoptosis in the pathogenesis and treatment of disease. Science 1995;267:1456-62.
-
(1995)
Science
, vol.267
, pp. 1456-1462
-
-
Thompson, C.B.1
-
3
-
-
0032575750
-
Caspases: Enemies within
-
Thornberry NA, Lazebnik Y. Caspases: enemies within. Science 1998;281:1312-6. (Pubitemid 28406817)
-
(1998)
Science
, vol.281
, Issue.5381
, pp. 1312-1316
-
-
Thornberry, N.A.1
Lazebnik, Y.2
-
4
-
-
0347601880
-
A decade of caspases
-
DOI 10.1038/sj.onc.1207107
-
Degterev A, Boyce M, Yuan J. A decade of caspases. Oncogene 2003;22:8543-67. (Pubitemid 38028527)
-
(2003)
Oncogene
, vol.22
, Issue.53 REV. ISS. 7
, pp. 8543-8567
-
-
Degterev, A.1
Boyce, M.2
Yuan, J.3
-
5
-
-
0036205587
-
Mechanisms of caspase activation and inhibition during apoptosis
-
DOI 10.1016/S1097-2765(02)00482-3
-
Shi Y. Mechanisms of caspase activation and inhibition during apoptosis. Mol Cell 2002;9:459-70. (Pubitemid 34273778)
-
(2002)
Molecular Cell
, vol.9
, Issue.3
, pp. 459-470
-
-
Shi, Y.1
-
6
-
-
0033082995
-
IAP family proteins-suppressors of apoptosis
-
Deveraux QL, Reed JC. IAP family proteins-suppressors of apoptosis. Genes Dev 1999;13:239-52.
-
(1999)
Genes Dev
, vol.13
, pp. 239-252
-
-
Deveraux, Q.L.1
Reed, J.C.2
-
7
-
-
43049091895
-
IAPs: What's in a Name?
-
DOI 10.1016/j.molcel.2008.03.008, PII S1097276508002086
-
Srinivasula SM, Ashwell JD. IAPs: what's in a name? Mol Cell 2008;30:123-35. (Pubitemid 351626688)
-
(2008)
Molecular Cell
, vol.30
, Issue.2
, pp. 123-135
-
-
Srinivasula, S.M.1
Ashwell, J.D.2
-
8
-
-
77449136104
-
XIAP as a ubiquitin ligase in cellular signaling
-
Galban S, Duckett CS. XIAP as a ubiquitin ligase in cellular signaling. Cell Death Differ 2010;17:54-60.
-
(2010)
Cell Death Differ
, vol.17
, pp. 54-60
-
-
Galban, S.1
Duckett, C.S.2
-
9
-
-
50049110244
-
Regulation of apoptosis by XIAP ubiquitin-ligase activity
-
Schile AJ, Garcia-Fernandez M, Steller H. Regulation of apoptosis by XIAP ubiquitin-ligase activity. Genes Dev 2008;22:2256-66.
-
(2008)
Genes Dev
, vol.22
, pp. 2256-2266
-
-
Schile, A.J.1
Garcia-Fernandez, M.2
Steller, H.3
-
10
-
-
33749252583
-
Human inhibitor of apoptosis proteins: Why XIAP is the black sheep of the family
-
DOI 10.1038/sj.embor.7400795, PII 7400795
-
Eckelman BP, Salvesen GS, Scott FL. Human inhibitor of apoptosis proteins: why XIAP is the black sheep of the family. EMBO Rep 2006;7:988-94. (Pubitemid 44480512)
-
(2006)
EMBO Reports
, vol.7
, Issue.10
, pp. 988-994
-
-
Eckelman, B.P.1
Salvesen, G.S.2
Scott, F.L.3
-
11
-
-
0030810926
-
X-linked IAP is a direct inhibitor of cell-death proteases
-
DOI 10.1038/40901
-
Deveraux QL, Takahashi R, Salvesen GS, Reed JC. X-linked IAP is a direct inhibitor of cell-death proteases. Nature 1997;388:300-4. (Pubitemid 27317977)
-
(1997)
Nature
, vol.388
, Issue.6639
, pp. 300-304
-
-
Deveraux, Q.L.1
Takahashi, R.2
Salvesen, G.S.3
Reed, J.C.4
-
12
-
-
55549140475
-
IAPs contain an evolutionarily conserved ubiquitin-binding domain that regulates NF-kappaB as well as cell survival and oncogenesis
-
Gyrd-Hansen M, Darding M, Miasari M, Santoro MM, Zender L, Xue W, et al. IAPs contain an evolutionarily conserved ubiquitin-binding domain that regulates NF-kappaB as well as cell survival and oncogenesis. Nat Cell Biol 2008;10:1309-17.
-
(2008)
Nat Cell Biol
, vol.10
, pp. 1309-1317
-
-
Gyrd-Hansen, M.1
Darding, M.2
Miasari, M.3
Santoro, M.M.4
Zender, L.5
Xue, W.6
-
13
-
-
0034616945
-
Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition
-
Du C, Fang M, Li Y, Li L, Wang X. Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition. Cell 2000;102:33-42.
-
(2000)
Cell
, vol.102
, pp. 33-42
-
-
Du, C.1
Fang, M.2
Li, Y.3
Li, L.4
Wang, X.5
-
14
-
-
0034616942
-
Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins
-
Verhagen AM, Ekert PG, Pakusch M, Silke J, Connolly LM, Reid GE, et al. Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins. Cell 2000;102:43-53.
-
(2000)
Cell
, vol.102
, pp. 43-53
-
-
Verhagen, A.M.1
Ekert, P.G.2
Pakusch, M.3
Silke, J.4
Connolly, L.M.5
Reid, G.E.6
-
15
-
-
0034785591
-
A serine protease, HtrA2, is released from the mitochondria and interacts with XIAP, inducing cell death
-
DOI 10.1016/S1097-2765(01)00341-0
-
Suzuki Y, Imai Y, Nakayama H, Takahashi K, Takio K, Takahashi R. A serine protease, HtrA2, is released from the mitochondria and interacts with XIAP, inducing cell death. Mol Cell 2001;8:613-21. (Pubitemid 32946938)
-
(2001)
Molecular Cell
, vol.8
, Issue.3
, pp. 613-621
-
-
Suzuki, Y.1
Imai, Y.2
Nakayama, H.3
Takahashi, K.4
Takio, K.5
Takahashi, R.6
-
16
-
-
18244386261
-
The serine protease Omi/HtrA2 is released from mitochondria during apoptosis. Omi interacts with caspase-inhibitor XIAP and induces enhanced caspase activity
-
DOI 10.1038/sj.cdd.4400970
-
van Loo G, van Gurp M, Depuydt B, Srinivasula SM, Rodriguez I, Alnemri ES, et al. The serine protease Omi/HtrA2 is released from mitochondria during apoptosis. Omi interacts with caspase-inhibitor XIAP and induces enhanced caspase activity. Cell Death Differ 2002;9:20-6. (Pubitemid 34071990)
-
(2002)
Cell Death and Differentiation
, vol.9
, Issue.1
, pp. 20-26
-
-
Van Loo, G.1
Van Gurp, M.2
Depuydt, B.3
Srinivasula, S.M.4
Rodriguez, I.5
Alnemri, E.S.6
Gevaert, K.7
Vandekerckhove, J.8
Declercq, W.9
Vandenabeele, P.10
-
17
-
-
0033671655
-
Anovel mitochondrial septin-like protein, ARTS, mediates apoptosis dependent on its P-loop motif
-
Larisch S, Yi Y, Lotan R, Kerner H, Eimerl S, Tony Parks W, et al. Anovel mitochondrial septin-like protein, ARTS, mediates apoptosis dependent on its P-loop motif. Nat Cell Biol 2000;2:915-21.
-
(2000)
Nat Cell Biol
, vol.2
, pp. 915-921
-
-
Larisch, S.1
Yi, Y.2
Lotan, R.3
Kerner, H.4
Eimerl, S.5
Tony Parks, W.6
-
18
-
-
2342561882
-
The mitochondrial ARTS protein promotes apoptosis through targeting XIAP
-
DOI 10.1038/sj.emboj.7600155
-
Gottfried Y, Rotem A, Lotan R, Steller H, Larisch S. The mitochondrial ARTS protein promotes apoptosis through targeting XIAP. EMBO J 2004;23:1627-35. (Pubitemid 38579523)
-
(2004)
EMBO Journal
, vol.23
, Issue.7
, pp. 1627-1635
-
-
Gottfried, Y.1
Rotem, A.2
Lotan, R.3
Steller, H.4
Larisch, S.5
-
19
-
-
0034651791
-
Induction of apoptosis by Drosophila reaper, hid and grim through inhibition of IAP function
-
Goyal L, McCall K, Agapite J, Hartwieg E, Steller H. Induction of apoptosis by Drosophila reaper, hid and grim through inhibition of IAP function. EMBO J 2000;19:589-97. (Pubitemid 30093732)
-
(2000)
EMBO Journal
, vol.19
, Issue.4
, pp. 589-597
-
-
Goyal, L.1
McCall, K.2
Agapite, J.3
Hartwieg, E.4
Steller, H.5
-
20
-
-
19444386896
-
Apoptosis in Drosophila: Neither fish nor fowl (nor man, nor worm)
-
DOI 10.1242/jcs.02377
-
Kornbluth S, White K. Apoptosis in Drosophila: neither fish nor fowl (nor man, nor worm). J Cell Sci 2005;118:1779-87. (Pubitemid 40723823)
-
(2005)
Journal of Cell Science
, vol.118
, Issue.9
, pp. 1779-1787
-
-
Kornbluth, S.1
White, K.2
-
21
-
-
0034700495
-
Structural basis for binding of Smac/DIABLO to the XIAP BIR3 domain
-
DOI 10.1038/35050006
-
Liu Z, Sun C, Olejniczak ET, Meadows RP, Betz SF, Oost T, et al. Structural basis for binding of Smac/DIABLO to the XIAP BIR3 domain. Nature 2000;408:1004-8. (Pubitemid 32101650)
-
(2000)
Nature
, vol.408
, Issue.6815
, pp. 1004-1008
-
-
Liu, Z.1
Sun, C.2
Olejniczak, E.T.3
Meadows, R.P.4
Betz, S.F.5
Oost, T.6
Herrmann, J.7
Wu, J.C.8
Fesik, S.W.9
-
22
-
-
84855717013
-
The IAP-antagonist ARTS initiates caspase activation upstream of cytochrome C and SMAC/Diablo
-
Edison N, Zuri D, Maniv I, Bornstein B, Lev T, Gottfried Y, et al. The IAP-antagonist ARTS initiates caspase activation upstream of cytochrome C and SMAC/Diablo. Cell Death Differ 2012;19:356-68.
-
(2012)
Cell Death Differ
, vol.19
, pp. 356-368
-
-
Edison, N.1
Zuri, D.2
Maniv, I.3
Bornstein, B.4
Lev, T.5
Gottfried, Y.6
-
23
-
-
21844444804
-
Regulation of the proapoptotic ARTS protein by ubiquitin-mediated degradation
-
DOI 10.1074/jbc.M501955200
-
Lotan R, Rotem A, Gonen H, Finberg JP, Kemeny S, Steller H, et al. Regulation of the proapoptotic ARTS protein by ubiquitin-mediated degradation. J Biol Chem 2005;280:25802-10. (Pubitemid 40962290)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.27
, pp. 25802-25810
-
-
Lotan, R.1
Rotem, A.2
Gonen, H.3
Finberg, J.P.M.4
Kemeny, S.5
Steller, H.6
Ciechanover, A.7
Larisch, S.8
-
24
-
-
80052437295
-
ARTS binds to a distinct domain in XIAP-BIR3 and promotes apoptosis by a mechanism that is different from other IAP-antagonists
-
Bornstein B, Gottfried Y, Edison N, Shekhtman A, Lev T, Glaser F, et al. ARTS binds to a distinct domain in XIAP-BIR3 and promotes apoptosis by a mechanism that is different from other IAP-antagonists. Apoptosis 2011;16:869-81.
-
(2011)
Apoptosis
, vol.16
, pp. 869-881
-
-
Bornstein, B.1
Gottfried, Y.2
Edison, N.3
Shekhtman, A.4
Lev, T.5
Glaser, F.6
-
25
-
-
0030041458
-
The septins: Roles in cytokinesis and other processes
-
DOI 10.1016/S0955-0674(96)80054-8
-
Longtine MS, DeMarini DJ, Valencik ML, Al-Awar OS, Fares H, De Virgilio C, et al. The septins: roles in cytokinesis and other processes. Curr Opin Cell Biol 1996;8:106-19. (Pubitemid 26059709)
-
(1996)
Current Opinion in Cell Biology
, vol.8
, Issue.1
, pp. 106-119
-
-
Longtine, M.S.1
DeMarini, D.J.2
Valencik, M.L.3
Al-Awar, O.S.4
Fares, H.5
De Virgilio, C.6
Pringle, J.R.7
-
26
-
-
84889378233
-
Septins and apoptosis
-
Hall PA, Russell SEH, Pringle JR, editors. London:Wiley Blackwell
-
Carp M-J, Larisch S. Septins and apoptosis. In:Hall PA, Russell SEH, Pringle JR, editors. The Septins. London:Wiley Blackwell; 2008. p. 281-95.
-
(2008)
The Septins
, pp. 281-295
-
-
Carp, M.-J.1
Larisch, S.2
-
27
-
-
80052735855
-
ARTS, the unusual septin: Structural and functional aspects
-
Mandel-Gutfreund Y, Kosti I, Larisch S. ARTS, the unusual septin: structural and functional aspects. Biol Chem 2011;392:783-90.
-
(2011)
Biol Chem
, vol.392
, pp. 783-790
-
-
Mandel-Gutfreund, Y.1
Kosti, I.2
Larisch, S.3
-
28
-
-
3843059163
-
Mitochondrial pro-apoptotic ARTS protein is lost in the majority of acute lymphoblastic leukemia patients
-
DOI 10.1038/sj.onc.1207725
-
Elhasid R, Sahar D, Merling A, Zivony Y, Rotem A, Ben-Arush M, et al. Mitochondrial pro-apoptotic ARTS protein is lost in the majority of acute lymphoblastic leukemia patients. Oncogene 2004;23:5468-75. (Pubitemid 39044057)
-
(2004)
Oncogene
, vol.23
, Issue.32
, pp. 5468-5475
-
-
Elhasid, R.1
Sahar, D.2
Merling, A.3
Zivony, Y.4
Rotem, A.5
Ben-Arush, M.6
Izraeli, S.7
Bercovich, D.8
Larisch, S.9
-
29
-
-
77958538177
-
Sept4/ARTS is required for stem cell apoptosis and tumor suppression
-
Garcia-Fernandez M, Kissel H, Brown S, Gorenc T, Schile AJ, Rafii S, et al. Sept4/ARTS is required for stem cell apoptosis and tumor suppression. Genes Dev 2010;24:2282-93.
-
(2010)
Genes Dev
, vol.24
, pp. 2282-2293
-
-
Garcia-Fernandez, M.1
Kissel, H.2
Brown, S.3
Gorenc, T.4
Schile, A.J.5
Rafii, S.6
-
30
-
-
17144438370
-
Expression and prognostic significance of IAP-family genes in human cancers and myeloid leukemias
-
Tamm I, Kornblau SM, Segall H, Krajewski S, Welsh K, Kitada S, et al. Expression and prognostic significance of IAP-family genes in human cancers and myeloid leukemias. Clin Cancer Res 2000;6:1796-803. (Pubitemid 30305074)
-
(2000)
Clinical Cancer Research
, vol.6
, Issue.5
, pp. 1796-1803
-
-
Tamm, I.1
Kornblau, S.M.2
Segall, H.3
Krajewski, S.4
Welsh, K.5
Kitada, S.6
Scudiero, D.A.7
Tudor, G.8
Qui, Y.H.9
Monks, A.10
Andreeff, M.11
Reed, J.C.12
-
31
-
-
34547126428
-
The inhibitors of apoptosis (IAPs) as cancer targets
-
DOI 10.1007/s10495-007-0087-3
-
Hunter AM, LaCasse EC, Korneluk RG. The inhibitors of apoptosis (IAPs) as cancer targets. Apoptosis 2007;12:1543-68. (Pubitemid 47106887)
-
(2007)
Apoptosis
, vol.12
, Issue.9
, pp. 1543-1568
-
-
Hunter, A.M.1
LaCasse, E.C.2
Korneluk, R.G.3
-
32
-
-
0034667372
-
Down-regulation of X-linked inhibitor of apoptosis protein induces apoptosis in chemoresistant human ovarian cancer cells
-
Sasaki H, Sheng Y, Kotsuji F, Tsang BK. Down-regulation of X-linked inhibitor of apoptosis protein induces apoptosis in chemoresistant human ovarian cancer cells. Cancer Res 2000;60:5659-66.
-
(2000)
Cancer Res
, vol.60
, pp. 5659-5666
-
-
Sasaki, H.1
Sheng, Y.2
Kotsuji, F.3
Tsang, B.K.4
-
33
-
-
75649131205
-
Simultaneous activation of p53 and inhibition of XIAP enhance the activation of apoptosis signaling pathways in AML
-
Carter BZ, Mak DH, Schober WD, Koller E, Pinilla C, Vassilev LT, et al. Simultaneous activation of p53 and inhibition of XIAP enhance the activation of apoptosis signaling pathways in AML. Blood 2009;115:306-14.
-
(2009)
Blood
, vol.115
, pp. 306-314
-
-
Carter, B.Z.1
Mak, D.H.2
Schober, W.D.3
Koller, E.4
Pinilla, C.5
Vassilev, L.T.6
-
34
-
-
44649097840
-
AEG-35156, an antisense oligonucleotide against X-linked inhibitor of apoptosis for the potential treatment of cancer
-
Tamm I. AEG-35156, an antisense oligonucleotide against X-linked inhibitor of apoptosis for the potential treatment of cancer. Curr Opin Investig Drugs 2008;9:638-46. (Pubitemid 351777167)
-
(2008)
Current Opinion in Investigational Drugs
, vol.9
, Issue.6
, pp. 638-646
-
-
Tamm, I.1
-
35
-
-
7944229824
-
Loss of XIAP protein expression by RNAi and antisense approaches sensitizes cancer cells to functionally diverse chemotherapeutics
-
DOI 10.1038/sj.onc.1207967
-
McManus DC, Lefebvre CA, Cherton-Horvat G, St-Jean M, Kandimalla ER, Agrawal S, et al. Loss of XIAP protein expression by RNAi and antisense approaches sensitizes cancer cells to functionally diverse chemotherapeutics. Oncogene 2004;23:8105-17. (Pubitemid 39531851)
-
(2004)
Oncogene
, vol.23
, Issue.49
, pp. 8105-8117
-
-
McManus, D.C.1
Lefebvre, C.A.2
Cherton-Horvat, G.3
St-Jean, M.4
Kandimalla, E.R.5
Agrawal, S.6
Morris, S.J.7
Durkin, J.P.8
LaCasse, E.C.9
-
36
-
-
54249123632
-
IAP-targeted therapies for cancer
-
LaCasse EC, Mahoney DJ, Cheung HH, Plenchette S, Baird S, Korneluk RG. IAP-targeted therapies for cancer. Oncogene 2008;27: 6252-75.
-
(2008)
Oncogene
, vol.27
, pp. 6252-6275
-
-
LaCasse, E.C.1
Mahoney, D.J.2
Cheung, H.H.3
Plenchette, S.4
Baird, S.5
Korneluk, R.G.6
-
37
-
-
35948950248
-
The inhibitor of apoptosis proteins as therapeutic targets in cancer
-
DOI 10.1158/1078-0432.CCR-07-0729
-
Vucic D, Fairbrother WJ. The inhibitor of apoptosis proteins as therapeutic targets in cancer. Clin Cancer Res 2007;13:5995-6000. (Pubitemid 350075054)
-
(2007)
Clinical Cancer Research
, vol.13
, Issue.20
, pp. 5995-6000
-
-
Vucic, D.1
Fairbrother, W.J.2
-
38
-
-
0036341291
-
Smac agonists sensitize for Apo2L/TRAIL- Or anticancer drug-induced apoptosis and induce regression of malignant glioma in vivo
-
Fulda S, Wick W, Weller M, Debatin KM. Smac agonists sensitize for Apo2L/TRAIL- or anticancer drug-induced apoptosis and induce regression of malignant glioma in vivo. Nat Med 2002;8:808-15.
-
(2002)
Nat Med
, vol.8
, pp. 808-815
-
-
Fulda, S.1
Wick, W.2
Weller, M.3
Debatin, K.M.4
-
39
-
-
36048999753
-
IAP Antagonists Induce Autoubiquitination of c-IAPs, NF-kappaB Activation, and TNFalpha-Dependent Apoptosis
-
DOI 10.1016/j.cell.2007.10.030, PII S0092867407013487
-
Varfolomeev E, Blankenship JW, Wayson SM, Fedorova AV, Kayagaki N, Garg P, et al. IAP antagonists induce autoubiquitination of c-IAPs, NF-kappaB activation, and TNFalpha-dependent apoptosis. Cell 2007;131:669-81. (Pubitemid 350087204)
-
(2007)
Cell
, vol.131
, Issue.4
, pp. 669-681
-
-
Varfolomeev, E.1
Blankenship, J.W.2
Wayson, S.M.3
Fedorova, A.V.4
Kayagaki, N.5
Garg, P.6
Zobel, K.7
Dynek, J.N.8
Elliott, L.O.9
Wallweber, H.J.A.10
Flygare, J.A.11
Fairbrother, W.J.12
Deshayes, K.13
Dixit, V.M.14
Vucic, D.15
-
40
-
-
80052944668
-
Mechanism of the interaction between the intrinsically disordered C-terminus of the pro-apoptotic ARTS protein and the Bir3 domain of XIAP
-
Reingewertz TH, Shalev DE, Sukenik S, Blatt O, Rotem-Bamberger S, Lebendiker M, et al. Mechanism of the interaction between the intrinsically disordered C-terminus of the pro-apoptotic ARTS protein and the Bir3 domain of XIAP. PLoS One 2011;6:e24655.
-
(2011)
PLoS One
, vol.6
-
-
Reingewertz, T.H.1
Shalev, D.E.2
Sukenik, S.3
Blatt, O.4
Rotem-Bamberger, S.5
Lebendiker, M.6
-
41
-
-
0035988372
-
The serine protease Omi/HtrA2: A second mammalian protein with a Reaper-like function
-
DOI 10.1038/sj.cdd.4401044
-
Martins LM. The serine protease Omi/HtrA2: a second mammalian protein with a Reaper-like function. Cell Death Differ 2002;9:699-701. (Pubitemid 34778035)
-
(2002)
Cell Death and Differentiation
, vol.9
, Issue.7
, pp. 699-701
-
-
Martins, L.M.1
-
42
-
-
0034739803
-
Characterization and expression analysis of two human septin genes, PNUTL1 and PNUTL2
-
DOI 10.1016/S0378-1119(00)00527-8, PII S0378111900005278
-
Zieger B, Tran H, Hainmann I, Wunderle D, Zgaga-Griesz A, Blaser S, et al. Characterization and expression analysis of two human septin genes, PNUTL1 and PNUTL2. Gene 2000;261:197-203. (Pubitemid 32146489)
-
(2000)
Gene
, vol.261
, Issue.2
, pp. 197-203
-
-
Zieger, B.1
Tran, H.2
Hainmann, I.3
Wunderle, D.4
Zgaga-Griesz, A.5
Blaser, S.6
Ware, J.7
-
43
-
-
69249208481
-
XIAP discriminates between type I and type II FAS-induced apoptosis
-
Jost PJ, Grabow S, Gray D, McKenzie MD, Nachbur U, Huang DC, et al. XIAP discriminates between type I and type II FAS-induced apoptosis. Nature 2009;460:1035-9.
-
(2009)
Nature
, vol.460
, pp. 1035-1039
-
-
Jost, P.J.1
Grabow, S.2
Gray, D.3
McKenzie, M.D.4
Nachbur, U.5
Huang, D.C.6
-
44
-
-
36749062005
-
X-linked inhibitor of apoptosis protein as a therapeutic target
-
DOI 10.1517/14728222.11.11.1459
-
Dean EJ, Ranson M, Blackhall F, Dive C. X-linked inhibitor of apoptosis protein as a therapeutic target. Expert Opin Ther Targets 2007;11:1459-71. (Pubitemid 350200481)
-
(2007)
Expert Opinion on Therapeutic Targets
, vol.11
, Issue.11
, pp. 1459-1471
-
-
Dean, E.J.1
Ranson, M.2
Blackhall, F.3
Dive, C.4
-
45
-
-
4444243683
-
A small molecule smac mimic potentiates TRAIL- and TNFalpha-mediated cell death
-
DOI 10.1126/science.1098231
-
Li L, Thomas RM, Suzuki H, De Brabander JK, Wang X, Harran PG. A small molecule Smac mimic potentiates TRAIL- and TNFalpha-mediated cell death. Science 2004;305:1471-4. (Pubitemid 39167668)
-
(2004)
Science
, vol.305
, Issue.5689
, pp. 1471-1474
-
-
Li, L.1
Thomas, R.M.2
Suzuki, H.3
De Brabander, J.K.4
Wang, X.5
Harran, P.G.6
-
46
-
-
37049019494
-
Design, synthesis, and characterization of a potent, nonpeptide, cell-permeable, bivalent smac mimetic that concurrently targets both the BIR2 and BIR3 domains in XIAP
-
DOI 10.1021/ja074725f
-
Sun H, Nikolovska-Coleska Z, Lu J, Meagher JL, Yang CY, Qiu S, et al. Design, synthesis, and characterization of a potent, nonpeptide, cell-permeable, bivalent Smac mimetic that concurrently targets both the BIR2 and BIR3 domains in XIAP. J Am Chem Soc 2007;129:15279-94. (Pubitemid 350247811)
-
(2007)
Journal of the American Chemical Society
, vol.129
, Issue.49
, pp. 15279-15294
-
-
Sun, H.1
Nikolovska-Coleska, Z.2
Lu, J.3
Meagher, J.L.4
Yang, C.-Y.5
Qiu, S.6
Tomita, Y.7
Ueda, Y.8
Jiang, S.9
Krajewski, K.10
Roller, P.P.11
Stuckey, J.A.12
Wang, S.13
-
47
-
-
36148954336
-
IAP Antagonists Target cIAP1 to Induce TNFalpha-Dependent Apoptosis
-
DOI 10.1016/j.cell.2007.10.037, PII S0092867407013578
-
Vince JE, Wong WW, Khan N, Feltham R, Chau D, Ahmed AU, et al. IAP antagonists target cIAP1 to induce TNFalpha-dependent apoptosis. Cell 2007;131:682-93. (Pubitemid 350103599)
-
(2007)
Cell
, vol.131
, Issue.4
, pp. 682-693
-
-
Vince, J.E.1
Wong, W.W.-L.2
Khan, N.3
Feltham, R.4
Chau, D.5
Ahmed, A.U.6
Benetatos, C.A.7
Chunduru, S.K.8
Condon, S.M.9
McKinlay, M.10
Brink, R.11
Leverkus, M.12
Tergaonkar, V.13
Schneider, P.14
Callus, B.A.15
Koentgen, F.16
Vaux, D.L.17
Silke, J.18
-
48
-
-
0034886271
-
Structural analysis of a functional DIAP1 fragment bound to Grim and Hid peptides
-
DOI 10.1016/S1097-2765(01)00282-9
-
Wu JW, Cocina AE, Chai J, Hay BA, Shi Y. Structural analysis of a functional DIAP1 fragment bound to grim and hid peptides. Mol Cell 2001;8:95-104. (Pubitemid 32772908)
-
(2001)
Molecular Cell
, vol.8
, Issue.1
, pp. 95-104
-
-
Wu, J.-W.1
Cocina, A.E.2
Chai, J.3
Hay, B.A.4
Shi, Y.5
-
49
-
-
78650746228
-
ARTS and Siah collaborate in a pathway for XIAP degradation
-
Garrison JB, Correa RG, Gerlic M, Yip KW, Krieg A, Tamble CM, et al. ARTS and Siah collaborate in a pathway for XIAP degradation. Mol Cell 2010;41:107-16.
-
(2010)
Mol Cell
, vol.41
, pp. 107-116
-
-
Garrison, J.B.1
Correa, R.G.2
Gerlic, M.3
Yip, K.W.4
Krieg, A.5
Tamble, C.M.6
-
50
-
-
35948994157
-
Autocrine TNFalpha Signaling Renders Human Cancer Cells Susceptible to Smac-Mimetic-Induced Apoptosis
-
DOI 10.1016/j.ccr.2007.08.029, PII S1535610807002619
-
Petersen SL, Wang L, Yalcin-Chin A, Li L, Peyton M, Minna J, et al. Autocrine TNFalpha signaling renders human cancer cells susceptible to Smac-mimetic-induced apoptosis. Cancer Cell 2007;12:445-56 (Pubitemid 350064365)
-
(2007)
Cancer Cell
, vol.12
, Issue.5
, pp. 445-456
-
-
Petersen, S.L.1
Wang, L.2
Yalcin-Chin, A.3
Li, L.4
Peyton, M.5
Minna, J.6
Harran, P.7
Wang, X.8
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