The IAP-antagonist ARTS initiates caspase activation upstream of cytochrome C and SMACDiablo

Cell Death and Differentiation

Volumn 19, Issue 2, 2012, Pages 356-368

  Edison, N ^a,b   Zuri, D ^a   Maniv, I ^a   Bornstein, B ^a   Lev, T ^a   Gottfried, Y ^a   Kemeny, S ^a   Garcia Fernandez, M ^c   Kagan, J ^a   Larisch, S ^a  

^a UNIVERSITY OF HAIFA   (Israel)

^b TECHNION ISRAEL INSTITUTE OF TECHNOLOGY   (Israel)

^c Centro Nacional de Investigaciones Oncológicas   (Spain)

Author keywords

apoptosis; ARTS; caspases; mitochondria; XIAP

Indexed keywords

CASPASE; CASPASE 9; CYTOCHROME C; PROTEIN ARTS; PROTEIN BID; SECOND MITOCHONDRIAL ACTIVATOR OF CASPASE; TUMOR SUPPRESSOR PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL SURVIVAL; COMPLEX FORMATION; CYTOSOL; DOWN REGULATION; ENZYME ACTIVATION; ENZYME ACTIVITY; HELA CELL; HUMAN; HUMAN CELL; MEMBRANE PERMEABILITY; MITOCHONDRIAL MEMBRANE; MITOCHONDRION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; PROTEIN SECRETION; SIGNAL TRANSDUCTION;

ANIMALS; APOPTOSIS; BH3 INTERACTING DOMAIN DEATH AGONIST PROTEIN; CASPASE 9; CERCOPITHECUS AETHIOPS; COS CELLS; CYTOCHROMES C; CYTOSOL; ENZYME ACTIVATION; HELA CELLS; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MITOCHONDRIA; MITOCHONDRIAL MEMBRANES; MITOCHONDRIAL PROTEINS; MODELS, BIOLOGICAL; PROTEIN TRANSPORT; SEPTINS; X-LINKED INHIBITOR OF APOPTOSIS PROTEIN;

EID: 84855717013     PISSN: 13509047     EISSN: 14765403     Source Type: Journal    
DOI: 10.1038/cdd.2011.112     Document Type: Article

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