A novel mitochondrial septin-like protein, ARTS, mediates apoptosis dependent on its P-loop motif

Nature Cell Biology

Volumn 2, Issue 12, 2000, Pages 915-921

  Larisch, Sarit ^a   Yi, Youngsuk ^b   Lotan, Rona ^a   Kerner, Hedviga ^a   Eimerl, Sarah ^b   Tony Parks, W ^b   Gottfried, Yossi ^a   Birkey Reffey, Stephanie ^b   De Caestecker, Mark P ^b   Danielpour, David ^c   Book Melamed, Naomi ^d   Timberg, Rina ^d   Duckett, Colin S ^b   Lechleider, Robert J ^b,e   Steller, Hermann ^f   Orly, Joseph ^d   Kim, Seong Jin ^b   Roberts, Anita B ^b  

^a RAMBAM MEDICAL CENTER   (Israel)

^b NATIONAL CANCER INSTITUTE   (United States)

^c CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d HEBREW UNIVERSITY OF JERUSALEM   (Israel)

^e UNIFORMED SERVICES UNIVERSITY OF THE HEALTH SCIENCES   (United States)

^f MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 3; CYTOKINE; GENE PRODUCT; PROTEIN DERIVATIVE; REV PROTEIN; SEPTIN; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL CELL; APOPTOSIS; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; GENE MUTATION; MITOCHONDRION; MOLECULAR CLONING; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN STRUCTURE; PROTEIN TRANSPORT; RAT;

AMINO ACID MOTIFS; AMINO ACID SEQUENCE; ANIMALS; APOPTOSIS; BASE SEQUENCE; CASPASES; CLONING, MOLECULAR; COS CELLS; CYTOSKELETAL PROTEINS; DNA PRIMERS; ENZYME ACTIVATION; GENE EXPRESSION; GTP PHOSPHOHYDROLASES; HUMANS; MITOCHONDRIA; MOLECULAR SEQUENCE DATA; SEQUENCE HOMOLOGY, AMINO ACID; SIGNAL TRANSDUCTION; TRANSFECTION; TRANSFORMING GROWTH FACTOR BETA;

ANIMALIA;

EID: 0033671655     PISSN: 14657392     EISSN: None     Source Type: Journal    
DOI: 10.1038/35046566     Document Type: Article

References (41)

1. Apoptosis in the pathogenesis and treatment of disease
2. Cell death in development
3. Caspases: Killer proteases
4. Caspases: Enemies within
5. Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3
6. DFF, a heterodimeric protein that functions downstream of caspase-3 to trigger DNA fragmentation during apoptosis
7. Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade
8. Molecular characterization of mitochondrial apoptosis-inducing factor
9. Regulation of apoptosis induced by transforming growth factor-beta1 in nontumorigenic rat prostatic epithelial cell lines
10. Three distinct roles for TGF-beta during intercellular induction of apoptosis: A review
11. Controlling TGP-beta signaling
12. Transforming growth factor-beta signaling in epithelial cells
13. Interdependent SMAD and JNK signaling in transforming growth factor-beta-mediated transcription
14. Selective loss of the transforming growth factor-beta apoptotic signaling pathway in mutant NRP-154 rat prostatic epithelial cells
15. Septins: Cytoskeletal polymers or signalling GTPases?
16. Characterization of the mammalian septin H5: Distinct patterns of cytoskeletal and membrane association from other septin proteins
17. A human gene similar to Drosophila melanogaster peanut maps to the DiGeorge syndrome region of 22q11
18. Alternative expression of platelet glycoprotein Ib(beta) mRNA from an adjacent 5' gene with an imperfect polyadenylation signal sequence
19. The P-loop - A common motif in ATP- and GTP-binding proteins
20. The domains of death: Evolution of the apoptosis machinery
21. The Caenorhabditis elegans cell death gene ced-4 encodes a novel protein and is expressed during the period of extensive programmed cell death
22. The death inhibitory molecules CED-9 and CED-4L use a common mechanism to inhibit the CED-3 death protease
23. The septin CDCrel-1 binds syntaxin and inhibits exocytosis
24. ICE-like protease (caspase) is involved in transforming growth factor beta1-mediated apoptosis in FaO rat hepatoma cell line
25. CrmA-inhibitable cleavage of the 70-kDa protein component of the U1 small nuclear ribonucleoprotein during Fas- and tumor necrosis factor-induced apoptosis
26. Human IAP-like protein regulates programmed cell death downstream of BclxL and cytochrome c
27. Induction of apoptosis by DPC4, a transcriptional factor regulated by transforming growth factor-beta through stress-activated protein kinase/c-Jun N-terminal kinase (SAPK/INK) signaling pathway
28. Smad7 mediates apoptosis induced by transforming growth factor beta in prostatic carcinoma cells
29. Induction of apoptosis by Smad3 and down-regulation of Smad3 expression in response to TGF-beta in human normal lung epithelial cells
30. Suppression of transforming growth factor-beta-induced apoptosis through a phosphatidylinositol 3-kinase/Akt-dependent pathway
31. Effect of truncated forms of the steroidogenic acute regulatory protein on intramitochondrial cholesterol transfer
32. Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins
33. Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition
34. IAP family proteins - Suppressors of apoptosis
35. Mitochondria and apoptosis
36. Nedd5, a mammalian septin, is a novel cytoskeletal component interacting with actin-based structures
37. The Drosophila peanut gene is required for cytokinesis and encodes a protein similar to yeast putative bud neck filament proteins
38. Facing death in the fly: Genetic analysis of apoptosis in Drosophila
39. Cell proliferation and apoptosis
40. The effect of furosemide on calcium ion concentration in myocardial cells