Interaction of pyrrolobenzodiazepine (PBD) ligands with parallel intermolecular G-quadruplex complex using spectroscopy and ESI-MS

PLoS ONE

Volumn 7, Issue 4, 2012, Pages

  Raju, Gajjela ^a   Srinivas, Ragampeta ^a   Santhosh Reddy, Vangala ^a   Idris, Mohammed M ^b   Kamal, Ahmed ^a   Nagesh, Narayana ^b  

^a INDIAN INSTITUTE OF CHEMICAL TECHNOLOGY   (India)

^b CENTRE FOR CELLULAR AND MOLECULAR BIOLOGY   (India)

Author keywords

[No Author keywords available]

Indexed keywords

5,10,15,20 TETRAKIS(N METHYL 4 PYRIDYL)PORPHYRIN; BENZODIAZEPINE; GUANINE QUADRUPLEX; PORPHYRIN; PYRROLO[2,1 C][1,4]BENZODIAZEPINE DERIVATIVE; PYRROLOBENZODIAZEPINE; UNCLASSIFIED DRUG; BENZODIAZEPINE DERIVATIVE; LIGAND; PYRROLE DERIVATIVE; PYRROLO(2,1 C)(1,4)BENZODIAZEPINE; PYRROLO(2,1-C)(1,4)BENZODIAZEPINE;

ARTICLE; BINDING AFFINITY; BINDING SITE; CIRCULAR DICHROISM; COMPLEX FORMATION; CONTROLLED STUDY; DNA BINDING; DNA STRUCTURE; ELECTROSPRAY MASS SPECTROMETRY; FLUORESCENCE SPECTROSCOPY; ISOTHERMAL TITRATION CALORIMETRY; LIGAND BINDING; MOLECULAR INTERACTION; NONHUMAN; PROMOTER REGION; SEQUENCE ANALYSIS; SPECTROSCOPY; TELOMERE; TETRAHYMENA; TETRAHYMENA GLAUCOMA; ULTRAVIOLET SPECTROPHOTOMETRY; CHEMISTRY; DNA DENATURATION; METABOLISM; METHODOLOGY; TEMPERATURE;

TETRAHYMENA;

BENZODIAZEPINES; G-QUADRUPLEXES; LIGANDS; NUCLEIC ACID DENATURATION; PYRROLES; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; SPECTRUM ANALYSIS; TEMPERATURE; TETRAHYMENA;

EID: 84860460477     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0035920     Document Type: Article

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