2,6-Diphenylthiazolo[3,2-b][1,2,4]triazoles as telomeric G-quadruplex stabilizers

Bioorganic and Medicinal Chemistry Letters

Volumn 19, Issue 13, 2009, Pages 3434-3438

  El Bakali, Jamal ^a   Klupsch, Frédérique ^a   Guédin, Aurore ^b   Brassart, Bertrand ^c   Fontaine, Gaëlle ^d   Farce, Amaury ^d   Roussel, Pascal ^e   Houssin, Raymond ^a   Bernier, Jean Luc ^d   Chavatte, Philippe ^d   Mergny, Jean Louis ^b   Riou, Jean François ^b   Hénichart, Jean Pierre ^a  

^a Faculté des Sciences Pharmaceutiques et Biologiques Université de Lille   (France)

^b CNRS   (France)

^c UNIVERSITÉ DE REIMS CHAMPAGNE ARDENNE   (France)

^d UNIV LILLE   (France)

^e Ecole Nationale Superieure de Chimie de Lille   (France)

Author keywords

2,6 Diphenylthiazolo 3,2 b 1,2,4 triazole; Cancer; G quadruplex; Telomere

Indexed keywords

1,2,4 TRIAZOLE DERIVATIVE; 2,6 DIPHENYLTHIAZOLO[3,2 B][1,2,4]TRIAZOLE; DOUBLE STRANDED DNA; GUANINE QUADRUPLEX; UNCLASSIFIED DRUG;

ARTICLE; CYCLIZATION; DEBENZYLATION; DRUG DESIGN; DRUG STRUCTURE; DRUG SYNTHESIS; FLUORESCENCE RESONANCE ENERGY TRANSFER; MOLECULAR DOCKING; POLYMERIZATION; SAPONIFICATION; TELOMERE;

EID: 66749124825     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2009.05.025     Document Type: Article

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32. + conditions.