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Volumn 19, Issue 8, 2011, Pages 2565-2581

Synthesis and biological evaluation of estradiol linked pyrrolo[2,1-c][1,4]benzodiazepine (PBD) conjugates as potential anticancer agents

(11) Kamal, Ahmed a Kashi Reddy, M a Janaki Ramaiah, M a Rajender, a Surendranadha Reddy, J a Srikanth, Y V V a Dastagiri, D a Vijaya Bharathi, E a Pushpavalli, S N C V L a Sarma, Pranjal a Pal Bhadra, Manika a

a INDIAN INSTITUTE OF CHEMICAL TECHNOLOGY (India)

Author keywords

Anticancer agents; Apoptosis; Estradiol; HDACs; p21; p53; Pyrrolobenzodiazepine; Tubulin polymerisation; Tunel assay

Indexed keywords

1,2,3,11A TETRAHYDRO 8 HYDROXY 7 METHOXY 5H PYRROLO[2,1 C][1,4]BENZODIAZEPIN 5 ONE; ANTINEOPLASTIC AGENT; DOXORUBICIN; ESTRADIOL DERIVATIVE; PYRROLO[2,1 C][1,4]BENZODIAZEPINE; TRIAZOLE DERIVATIVE; TUBULIN; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; BREAST CANCER; CELL CYCLE; CELL STRAIN MCF 7; CONTROLLED STUDY; DRUG DESIGN; DRUG EFFECT; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; PROTEIN POLYMERIZATION;

ANTINEOPLASTIC AGENTS; BENZODIAZEPINES; BREAST NEOPLASMS; CELL CYCLE; CELL LINE, TUMOR; ESTRADIOL; ESTROGENS; FEMALE; HUMANS; PYRROLES; STRUCTURE-ACTIVITY RELATIONSHIP; TUBULIN;

EID: 79954423813 PISSN: 09680896 EISSN: None Source Type: Journal
DOI: 10.1016/j.bmc.2011.03.015 Document Type: Article

Times cited : (18)

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