Formation and recognition of G-quadruplex in promoter of c-myb oncogene by electrospray ionization mass spectrometry

Journal of Mass Spectrometry

Volumn 46, Issue 9, 2011, Pages 849-855

  Cui, Xiaojie ^a   Yuan, Gu ^a  

^a PEKING UNIVERSITY   (China)

Author keywords

autodock; c myb gene; dehydrocorydaline; ESI MS; G quadruplex

Indexed keywords

AUTODOCK; BINDING AFFINITIES; BINDING PROPERTIES; BINDING SELECTIVITY; CHINESE HERBS; DEHYDROCORYDALINE; DUPLEX DNA; ELECTROSPRAY IONIZATION MASS SPECTROMETRY; ESI-MS; G-QUADRUPLEXES; GAS-PHASE KINETIC STABILITY; PROMOTER REGION; SMALL MOLECULES;

BINDING ENERGY; BINDING SITES; GENES; IONIZATION OF GASES; MASS SPECTROMETRY; MOLECULES; PHASE STABILITY;

ELECTROSPRAY IONIZATION;

DEHYDROCORYDALINE; DOUBLE STRANDED DNA; GUANINE QUADRUPLEX; LIGAND; NATURAL PRODUCT; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; BINDING KINETICS; CIRCULAR DICHROISM; ELECTROSPRAY MASS SPECTROMETRY; ENERGY; MOLECULAR DOCKING; MOLECULAR RECOGNITION; MOLECULAR STABILITY; ONCOGENE C MYB; PHYSICAL PHASE; PRIORITY JOURNAL; PROMOTER REGION; TANDEM MASS SPECTROMETRY;

ALKALOIDS; BINDING SITES; CIRCULAR DICHROISM; G-QUADRUPLEXES; GENES, MYB; HUMANS; LIGANDS; PORPHYRINS; PROMOTER REGIONS, GENETIC; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; THERMODYNAMICS;

EID: 80052789067     PISSN: 10765174     EISSN: 10969888     Source Type: Journal    
DOI: 10.1002/jms.1959     Document Type: Article

References (27)

1. I. H. Oh, E. P. Reddy,. The myb gene family in cell growth, differentiation and apoptosis. Oncogene 1999, 18, 3017.
2. S. P. Duprey, D. Boettiger,. Developmental regulation of c-myb in normal myeloid progenitor cells. Proc. Natl Acad. Sci. U S A 1985, 82, 6937.
3. K. Todokoro, R. J. Watson, H. Higo, H. Amanuma, S. Kuramochi, H. Yanagisawa, Y. Ikawa,. Down-regulation of c-myb gene expression is a prerequisite for erythropoietin induced erythroid differentiation. Proc. Natl Acad. Sci. U S A 1988, 85, 8900.
4. H. K. Yi, S. Y. Nam, J. C. Kim, J. S. Kim, D. Y. Lee, P. H. Hwang,. Induction of apoptosis in K562 cells by dominant negative c-myb. Exp Hematol 2002, 30, 1139.
5. T. J. Gonda, D. Metcalf,. Expression of myb, myc and fos proto-oncogenes during the differentiation of a murine myeloid-leukemia. Nature 1984, 310, 249.
6. D. J. Slamon, T. C. Boone, D. C. Murdock, D. E. Keith, M. F. Press, R. A. Larson, L. M. Souza,. Studies of the human c-myb gene and its product in human acute leukemias. Science 1986, 233, 347.
7. C. Barletta, P. G. Pelicci, L. C. Kenyon, S. D. Smith, R. Dallafavera,. Relationship between the c-myb locus and the 6Q chromosomal aberration in leukemias and lymphomas. Science 1987, 235, 1064.
8. R. G. Ramsay, M. A. Thompson, J. A. Hayman, G. Reid, T. J. Gonda, R. H. Whitehead,. Myb expression is higher in malignant human colonic carcinoma and premalignant adenomatous polyps than in normal mucosa. Cell Growth Differ 1992, 3, 723.
9. A. M. Gewirtz, B. Calabretta,. A c-myb antisense oligodeoxynucleotide inhibits normal human hematopoiesis invitro. Science 1988, 242, 1303.
10. A. M. Gewirtz,. Myb targeted therapeutics for the treatment of human malignancies. Oncogene 1999, 18, 3056.
11. A. M. Gewirtz,. Oligodeoxynucleotide-based therapeutics for human leukemias. Stem Cells 1993, 11, 96.
12. A. Matsugami, K. Ouhashi, M. Kanagawa, H. Liu, S. Kanagawa, S. Uesugi, M. Katahira,. An intramolecular quadruplex of (GGA)(4) triplet repeat DNA with a G:G:G:G tetrad and a G(: A):G(: A):G(: A):G heptad, and its dimeric interaction. J. Mol. Biol. 2001, 313, 255.
13. A. Matsugami, T. Okuizumi, S. Uesugi, M. Katahira,. Intramolecular higher order packing of parallel quadruplexes comprising a G:G:G:G tetrad and a G(: A):G(: A):G(: A):G heptad of GGA triplet repeat DNA. J. Biol. Chem. 2003, 278, 28147.
14. S. L. Palumbo, R. M. Memmott, D. J. Uribe, Y. Krotova-Khan, L. H. Hurley, S. W. Ebbinghaus,. A novel G-quadruplex-forming GGA repeat region in the c-myb promoter is a critical regulator of promoter activity. Nucleic Acids Res. 2008, 36, 1755.
15. G. W. Collie, G. N. Parkinson, S. Neidle, F. Rosu, E. De Pauw, V. Gabelica,. Electrospray mass spectrometry of telomeric RNA (TERRA) reveals the formation of stable multimeric G-quadruplex structures. J. Am. Chem. Soc. 2010, 132, 9328.
16. C. L. Mazzitelli, J. S. Brodbelt, J. T. Kern, M. Rodriguez, S. M. Kerwin,. Evaluation of binding of perylene diimide and benzannulated perylene diimide ligands to DNA by electrospray ionization mass spectrometry. J. Am. Soc. Mass Spectrom. 2006, 17, 593.
17. H. H. Li, G. Yuan, D. M. Du,. Investigation of formation, recognition, stabilization, and conversion of dimeric G-Quadruplexes of HIV-1 integrase inhibitors by electrospray ionization mass spectrometry. J. Am. Soc. Mass Spectrom. 2008, 19, 550.
18. S. E. Pierce, R. Kieltyka, H. F. Sleiman, J. S. Brodbelt,. Evaluation of binding selectivities and affinities of platinum-based quadruplex interactive complexes by electrospray ionization mass spectrometry. Biopolymers 2009, 91, 233.
19. D. Monchaud, C. Allain, H. Bertrand, N. Smargiasso, F. Rosu, V. Gabelica, A. De Cian, J. L. Mergny, M. R. Teulade-Fichou,. Ligands playing musical chairs with G-quadruplex DNA: a rapid and simple displacement assay for identifying selective G-quadruplex binders. Biochimie 2008, 90, 1207.
20. V. Gabelica, F. Rosu, E. De Pauw,. A simple method to determine electrospray response factors of noncovalent complexes. Anal. Chem. 2009, 81, 6708.
21. S. Cogoi, L. E. Xodo,. Enhanced G4-DNA binding of 5,10,15,20 (N-propyl-4-pyridyl) porphyrin (TPrPyP4): a comparative study with TMPyP4. Chem. Commun. 2010, 46, 7364.
22. A. Membrino, M. Paramasivam, S. Cogoi, J. Alzeer, N. W. Luedtke, L. E. Xodo,. Cellular uptake and binding of guanidine-modified phthalocyanines to KRAS/HRAS G-quadruplexes. Chem. Commun. 2010, 46, 625.
23. Y. Mikami-Terao, M. Akiyama, Y. Yuza, T. Yanagisawa, O. Yamada, T. Kawano, M. Agawa, H. Ida, H. Yamada,. Antitumor activity of TMPyP4 interacting G-quadruplex in retinoblastoma cell lines. Exp. Eye Res. 2009, 89, 200.
24. Ruth Huey, William E. Hart, Richard K. Belew, Arthur J. Olson, G. M. Morris, D. S. Goodsell, R. S. Halliday, R. Huey, W. E. Hart, R. K. Belew, A. J. Olson,. Automated docking using a Lamarckian genetic algorithm and an empirical binding free energy function. J. Comput. Chem. 1998, 19, 1639.
25. H. H. Li, G. Yuan,. Collision-induced dissociation of dimeric G-quadruplexes of HIV-1 integrase inhibitors and their complexes by tandem-in-time mass spectrometry. Eur. J. Mass Spectrom. 2009, 15, 731.
26. T. P. Garner, H. E. L. Williams, K. I. Gluszyk, S. Roe, N. J. Oldham, M. F. G. Stevens, J. E. Moses, M. S. Searle,. Selectivity of small molecule ligands for parallel and anti-parallel DNA G-quadruplex structures. Org. Biomol. Chem. 2009, 7, 4194.
27. C. L. Mazzitelli, J. Wang, S. I. Smith, J. S. Brodbelt,. Gas-phase stability of G-quadruplex DNA determined by electrospray ionization tandem mass spectrometry and molecular dynamics Simulations. J. Am. Soc. Mass Spectrom. 2007, 18, 1760.