-
1
-
-
25844467036
-
Overview of tyrosine kinase inhibitors in clinical breast cancer
-
Agrawal A, Gutteridge E, Gee JM, Nicholson RI, Robertson JF (2005) Overview of tyrosine kinase inhibitors in clinical breast cancer. Endocr Relat Cancer 12:S135-S144
-
(2005)
Endocr Relat Cancer
, vol.12
-
-
Agrawal, A.1
Gutteridge, E.2
Gee, J.M.3
Nicholson, R.I.4
Robertson, J.F.5
-
2
-
-
34249739172
-
Treatment of human epidermal growth factor receptor 2-overexpressing breast cancer xenografts with multi-Agent HER-Targeted therapy
-
Arpino G, Gutierrez C, Weiss H, Rimawi M, Massarweh S, Bharwani L, De Placido S, Osborne CK, Schiff R (2007) Treatment of human epidermal growth factor receptor 2-overexpressing breast cancer xenografts with multi-Agent HER-Targeted therapy. J Natl Cancer Inst 99:694-705
-
(2007)
J Natl Cancer Inst
, vol.99
, pp. 694-705
-
-
Arpino, G.1
Gutierrez, C.2
Weiss, H.3
Rimawi, M.4
Massarweh, S.5
Bharwani, L.6
De Placido, S.7
Osborne, C.K.8
Schiff, R.9
-
3
-
-
42049121934
-
Crosstalk between the estrogen receptor and the HER tyrosine kinase receptor family: Molecular mechanism and clinical implications for endocrine therapy resistance
-
Arpino G, Wiechmann L, Osborne CK, Schiff R (2008) Crosstalk between the estrogen receptor and the HER tyrosine kinase receptor family: Molecular mechanism and clinical implications for endocrine therapy resistance. Endocr Rev 29:217-233
-
(2008)
Endocr Rev
, vol.29
, pp. 217-233
-
-
Arpino, G.1
Wiechmann, L.2
Osborne, C.K.3
Schiff, R.4
-
4
-
-
0033870250
-
Long-Term hydroxytamoxifen treatment of an MCF-7-derived breast cancer cell line irreversibly inhibits the expression of estrogenic genes through chromatin remodeling
-
Badia E, Duchesne MJ, Semlali A, Fuentes M, Giamarchi C, Richard-Foy H, Nicolas JC, Pons M (2000) Long-Term hydroxytamoxifen treatment of an MCF-7-derived breast cancer cell line irreversibly inhibits the expression of estrogenic genes through chromatin remodeling. Cancer Res 60:4130-4138
-
(2000)
Cancer Res
, vol.60
, pp. 4130-4138
-
-
Badia, E.1
Duchesne, M.J.2
Semlali, A.3
Fuentes, M.4
Giamarchi, C.5
Richard-Foy, H.6
Nicolas, J.C.7
Pons, M.8
-
5
-
-
0030865656
-
An intron 1 enhancer element mediates oestrogen-induced suppression of ERBB2 expression
-
Bates NP, Hurst HC (1997) An intron 1 enhancer element mediates oestrogen-induced suppression of ERBB2 expression. Oncogene 15:473-481
-
(1997)
Oncogene
, vol.15
, pp. 473-481
-
-
Bates, N.P.1
Hurst, H.C.2
-
6
-
-
0035393501
-
A CD44 survival pathway triggers chemoresistance via lyn kinase and phosphoinositide 3-kinase/akt in colon carcinoma cells
-
Bates RC, Edwards NS, Burns GF, Fisher DE (2001) A CD44 survival pathway triggers chemoresistance via lyn kinase and phosphoinositide 3-kinase/akt in colon carcinoma cells. Cancer Res 61:5275-5283
-
(2001)
Cancer Res
, vol.61
, pp. 5275-5283
-
-
Bates, R.C.1
Edwards, N.S.2
Burns, G.F.3
Fisher, D.E.4
-
7
-
-
84889996207
-
Anti-estrogens promote an invasive phenotype in intercellular adhesion deficient breast cancer cells
-
Borley AC, Barrett-Lee PJ, Gee JMW, Shaw V, Nicholson RI, Hiscox SE (2007) Anti-estrogens promote an invasive phenotype in intercellular adhesion deficient breast cancer cells. Breast Cancer Res Treat 106:S1, 24
-
(2007)
Breast Cancer Res Treat
, vol.106
, Issue.S1
, pp. 24
-
-
Borley, A.C.1
Barrett-Lee, P.J.2
Gee, J.M.W.3
Shaw, V.4
Nicholson, R.I.5
Hiscox, S.E.6
-
8
-
-
34249018367
-
GEFs and GAPs: Critical elements in the control of small g proteins
-
Bos JL, Rehmann H, Wittinghofer A (2007) GEFs and GAPs: Critical elements in the control of small g proteins. Cell 129:865-877
-
(2007)
Cell
, vol.129
, pp. 865-877
-
-
Bos, J.L.1
Rehmann, H.2
Wittinghofer, A.3
-
9
-
-
33645234316
-
Bidirectional cross talk between ERalpha and EGFR signalling pathways regulates tamoxifen-resistant growth
-
Britton DJ, Hutcheson IR, Knowlden JM, Barrow D, Giles M, McClelland RA, Gee JM, Nicholson RI (2006) Bidirectional cross talk between ERalpha and EGFR signalling pathways regulates tamoxifen-resistant growth. Breast Cancer Res Treat 96:131-146
-
(2006)
Breast Cancer Res Treat
, vol.96
, pp. 131-146
-
-
Britton, D.J.1
Hutcheson, I.R.2
Knowlden, J.M.3
Barrow, D.4
Giles, M.5
McClelland, R.A.6
Gee, J.M.7
Nicholson, R.I.8
-
10
-
-
40949157661
-
Epithelial progeny of estrogen-exposed breast progenitor cells display a cancer-like methylome
-
Cheng AS, Culhane AC, Chan MW, Venkataramu CR, Ehrich M, Nasir A, Rodriguez BA, Liu J, Yan PS, Quackenbush J, Nephew KP, Yeatman TJ, Huang TH (2008) Epithelial progeny of estrogen-exposed breast progenitor cells display a cancer-like methylome. Cancer Res 68:1786-1796
-
(2008)
Cancer Res
, vol.68
, pp. 1786-1796
-
-
Cheng, A.S.1
Culhane, A.C.2
Chan, M.W.3
Venkataramu, C.R.4
Ehrich, M.5
Nasir, A.6
Rodriguez, B.A.7
Liu, J.8
Yan, P.S.9
Quackenbush, J.10
Nephew, K.P.11
Yeatman, T.J.12
Huang, T.H.13
-
11
-
-
0030695954
-
Predictors of response to second-line endocrine therapy for breast cancer
-
Cheung KL, Willsher PC, Pinder SE, Ellis IO, Elston CW, Nicholson RI, Blamey RW, Robertson JF (1997) Predictors of response to second-line endocrine therapy for breast cancer. Breast Cancer Res Treat 45:219-224
-
(1997)
Breast Cancer Res Treat
, vol.45
, pp. 219-224
-
-
Cheung, K.L.1
Willsher, P.C.2
Pinder, S.E.3
Ellis, I.O.4
Elston, C.W.5
Nicholson, R.I.6
Blamey, R.W.7
Robertson, J.F.8
-
12
-
-
40949108361
-
Fulvestrant: Expanding the endocrine treatment options for patients with hormone receptor-positive advanced breast cancer
-
Chia S, Gradishar W (2008) Fulvestrant: Expanding the endocrine treatment options for patients with hormone receptor-positive advanced breast cancer. Breast 17:S16-S21
-
(2008)
Breast
, vol.17
-
-
Chia, S.1
Gradishar, W.2
-
13
-
-
0242442571
-
The gene expression response of breast cancer to growth regulators: Patterns and correlation with tumour expression profiles
-
Cunliffe HE, Ringner M, Bilke S, Walker RL, Cheung JM, Chen Y, Meltzer PS (2003) The gene expression response of breast cancer to growth regulators: Patterns and correlation with tumour expression profiles. Cancer Res 63:7158-7166
-
(2003)
Cancer Res
, vol.63
, pp. 7158-7166
-
-
Cunliffe, H.E.1
Ringner, M.2
Bilke, S.3
Walker, R.L.4
Cheung, J.M.5
Chen, Y.6
Meltzer, P.S.7
-
14
-
-
0037112507
-
An estrogen-responsive element-Targeted histone deacetylase enzyme has an antiestrogen activity that differs from that of hydroxytamoxifen
-
Demirpence E, Semlali A, Oliva J, Balaguer P, Badia E, Duchesne MJ, Nicolas JC, Pons M (2002) An estrogen-responsive element-Targeted histone deacetylase enzyme has an antiestrogen activity that differs from that of hydroxytamoxifen. Cancer Res 62:6519-6528
-
(2002)
Cancer Res
, vol.62
, pp. 6519-6528
-
-
Demirpence, E.1
Semlali, A.2
Oliva, J.3
Balaguer, P.4
Badia, E.5
Duchesne, M.J.6
Nicolas, J.C.7
Pons, M.8
-
15
-
-
0035342577
-
Multiple ways of silencing E-cadherin gene expression in lobular carcinoma of the breast
-
Droufakou S, Deshmane V, Roylance R, Hanby A, Tomlinson I, Hart IR (2001) Multiple ways of silencing E-cadherin gene expression in lobular carcinoma of the breast. Int J Cancer 92:404-408
-
(2001)
Int J Cancer
, vol.92
, pp. 404-408
-
-
Droufakou, S.1
Deshmane, V.2
Roylance, R.3
Hanby, A.4
Tomlinson, I.5
Hart, I.R.6
-
16
-
-
2642517107
-
Co-expression of neuregulins 1 2 3 and 4 in human breast cancer
-
Dunn M, Sinha P, Campbell R, Blackburn E, Levinson N, Rampaul R, Bates T, Humphreys S, Gullick WJ (2004) Co-expression of neuregulins 1, 2, 3 and 4 in human breast cancer. J Pathol 203:672-680
-
(2004)
J Pathol
, vol.203
, pp. 672-680
-
-
Dunn, M.1
Sinha, P.2
Campbell, R.3
Blackburn, E.4
Levinson, N.5
Rampaul, R.6
Bates, T.7
Humphreys, S.8
Gullick, W.J.9
-
17
-
-
33846207899
-
Diverse gene expression and DNA methylation profiles correlate with differential adaptation of breast cancer cells to the antiestrogens tamoxifen and fulvestrant
-
Fan M, Yan PS, Hartman-Frey C, Chen L, Paik H, Oyer SL, Salisbury JD, Cheng AS, Li L, Abbosh PH, Huang TH, Nephew KP (2006) Diverse gene expression and DNA methylation profiles correlate with differential adaptation of breast cancer cells to the antiestrogens tamoxifen and fulvestrant. Cancer Res 66:11954-11966
-
(2006)
Cancer Res
, vol.66
, pp. 11954-11966
-
-
Fan, M.1
Yan, P.S.2
Hartman-Frey, C.3
Chen, L.4
Paik, H.5
Oyer, S.L.6
Salisbury, J.D.7
Cheng, A.S.8
Li, L.9
Abbosh, P.H.10
Huang, T.H.11
Nephew, K.P.12
-
18
-
-
33847023585
-
Long-Term treatment with tamoxifen facilitates translocation of estrogen receptor alpha Out Of the nucleus and enhances its interaction with EGFR in MCF-7 breast cancer cells
-
Fan P, Wang J, Santen RJ, Yue W (2007) Long-Term treatment with tamoxifen facilitates translocation of estrogen receptor alpha Out Of the nucleus and enhances its interaction with EGFR in MCF-7 breast cancer cells. Cancer Res 67:1352-1360
-
(2007)
Cancer Res
, vol.67
, pp. 1352-1360
-
-
Fan, P.1
Wang, J.2
Santen, R.J.3
Yue, W.4
-
19
-
-
0842306968
-
Changes in vascular endothelial growth factor (VEGF) after chemoendocrine therapy in breast cancer
-
Fersis N, Smyczek-Gargya B, Armeanu S, Gagulic E, Pantic L, Relakis K, Friedrich M, Wallwiener D (2004) Changes in vascular endothelial growth factor (VEGF) after chemoendocrine therapy in breast cancer. Eur J Gynaecol Oncol 25:45-50
-
(2004)
Eur J Gynaecol Oncol
, vol.25
, pp. 45-50
-
-
Fersis, N.1
Smyczek-Gargya, B.2
Armeanu, S.3
Gagulic, E.4
Pantic, L.5
Relakis, K.6
Friedrich, M.7
Wallwiener, D.8
-
20
-
-
38849136014
-
Sixteen-kinase gene expression identifies luminal breast cancers with poor prognosis
-
Finetti P, Cervera N, Charafe-Jauffret E, Chabannon C, Charpin C, Chaffanet M, Jacquemier J, Viens P, Birnbaum D, Bertucci F (2008) Sixteen-kinase gene expression identifies luminal breast cancers with poor prognosis. Cancer Res 68:767-776
-
(2008)
Cancer Res
, vol.68
, pp. 767-776
-
-
Finetti, P.1
Cervera, N.2
Charafe-Jauffret, E.3
Chabannon, C.4
Charpin, C.5
Chaffanet, M.6
Jacquemier, J.7
Viens, P.8
Birnbaum, D.9
Bertucci, F.10
-
21
-
-
2442419137
-
Invasiveness of breast carcinoma cells and transcript profile: Eph receptors and ephrin ligands as molecular markers of potential diagnostic and prognostic application
-
Fox BP, Kandpal RP (2004) Invasiveness of breast carcinoma cells and transcript profile: Eph receptors and ephrin ligands as molecular markers of potential diagnostic and prognostic application. Biochem Biophys Res Commun 318:882-892
-
(2004)
Biochem Biophys Res Commun
, vol.318
, pp. 882-892
-
-
Fox, B.P.1
Kandpal, R.P.2
-
22
-
-
0141785350
-
Profiling of estrogen up-And down-regulated gene expression in human breast cancer cells: Insights into gene networks and pathways underlying estrogenic control of proliferation and cell phenotype
-
Frasor J, Danes JM, Komm B, Chang KC, Lyttle CR, Katzenellenbogen BS (2003) Profiling of estrogen up-And down-regulated gene expression in human breast cancer cells: Insights into gene networks and pathways underlying estrogenic control of proliferation and cell phenotype. Endocrinology 144:4562-4574
-
(2003)
Endocrinology
, vol.144
, pp. 4562-4574
-
-
Frasor, J.1
Danes, J.M.2
Komm, B.3
Chang, K.C.4
Lyttle, C.R.5
Katzenellenbogen, B.S.6
-
23
-
-
1242338758
-
Selective estrogen receptor modulators: Discrimination of agonistic versus antagonistic activities by gene expression profiling in breast cancer cells
-
Frasor J, Stossi F, Danes JM, Komm B, Lyttle CR, Katzenellenbogen BS (2004) Selective estrogen receptor modulators: Discrimination of agonistic versus antagonistic activities by gene expression profiling in breast cancer cells. Cancer Res 64:1522-1533
-
(2004)
Cancer Res
, vol.64
, pp. 1522-1533
-
-
Frasor, J.1
Stossi, F.2
Danes, J.M.3
Komm, B.4
Lyttle, C.R.5
Katzenellenbogen, B.S.6
-
24
-
-
25844477516
-
Understanding endocrine resistance: The critical need for sequential samples from clinical breast cancer and novel in vitro models
-
Gee JM, Hutcheson IR (2005) Understanding endocrine resistance: The critical need for sequential samples from clinical breast cancer and novel in vitro models. Breast Cancer Res Treat 7: 187-189
-
(2005)
Breast Cancer Res Treat
, vol.7
, pp. 187-189
-
-
Gee, J.M.1
Hutcheson, I.R.2
-
25
-
-
0032940738
-
Endocrine response and resistance in breast cancer: A role for the transcription factor fos
-
Gee JM, Willsher PC, Kenny FS, Robertson JF, Pinder SE, Ellis IO, Nicholson RI (1999) Endocrine response and resistance in breast cancer: A role for the transcription factor fos. Int J Cancer 84:54-61
-
(1999)
Int J Cancer
, vol.84
, pp. 54-61
-
-
Gee, J.M.1
Willsher, P.C.2
Kenny, F.S.3
Robertson, J.F.4
Pinder, S.E.5
Ellis, I.O.6
Nicholson, R.I.7
-
26
-
-
0242721012
-
The anti-epidermal growth factor receptor agent gefitinib (ZD1839/iressa) improves anti-hormone response and prevents development of resistance in breast cancer in vitro
-
Gee JM, Harper ME, Hutcheson IR, Madden TA, Barrow D, Knowlden JM, McClelland RA, Jordan N, Wakeling AE, Nicholson RI (2003) The anti-epidermal growth factor receptor agent gefitinib (ZD1839/iressa) improves anti-hormone response and prevents development of resistance in breast cancer in vitro. Endocrinology 144:5105-5117
-
(2003)
Endocrinology
, vol.144
, pp. 5105-5117
-
-
Gee, J.M.1
Harper, M.E.2
Hutcheson, I.R.3
Madden, T.A.4
Barrow, D.5
Knowlden, J.M.6
McClelland, R.A.7
Jordan, N.8
Wakeling, A.E.9
Nicholson, R.I.10
-
27
-
-
33846888637
-
Array profiling of survival and resistance genes in anti-hormone-Treated breast cancer cells
-
Gee J, Shaw V, Burmi R, McClelland R, Morgan H, Harper M, Hiscox S, Barrow D, Lewis P, Nicholson R (2004) Array profiling of survival and resistance genes in anti-hormone-Treated breast cancer cells. Intl J Mol Med 14:S81
-
(2004)
Intl J Mol Med
, vol.14
-
-
Gee, J.1
Shaw, V.2
Burmi, R.3
McClelland, R.4
Morgan, H.5
Harper, M.6
Hiscox, S.7
Barrow, D.8
Lewis, P.9
Nicholson, R.10
-
28
-
-
25844468319
-
Epidermal growth factor receptor/HER2/insulin-like growth factor receptor signalling and oestrogen receptor activity in clinical breast cancer
-
Gee JM, Robertson JF, Gutteridge E, Ellis IO, Pinder SE, Rubini M, Nicholson RI (2005a) Epidermal growth factor receptor/HER2/insulin-like growth factor receptor signalling and oestrogen receptor activity in clinical breast cancer. Endocr Relat Cancer 12:S99-S111
-
(2005)
Endocr Relat Cancer
, vol.12
-
-
Gee, J.M.1
Robertson, J.F.2
Gutteridge, E.3
Ellis, I.O.4
Pinder, S.E.5
Rubini, M.6
Nicholson, R.I.7
-
29
-
-
25844500946
-
Consensus statement workshop on therapeutic resistance in breast cancer: Impact of growth factor signalling pathways and implications for future treatment
-
Gee JM, Howell A, Gullick WJ, Benz CC, Sutherland RL, Santen RJ, Martin LA, Ciardiello F, Miller WR, Dowsett M, Barrett-Lee P, Robertson JF, Johnston Jones SRHE, Wakeling AE, Duncan R, Nicholson RI (2005b) Consensus statement. Workshop on therapeutic resistance in breast cancer: Impact of growth factor signalling pathways and implications for future treatment. Endocr Relat Cancer 12:S1-S7
-
(2005)
Endocr Relat Cancer
, vol.12
-
-
Gee, J.M.1
Howell, A.2
Gullick, W.J.3
Benz, C.C.4
Sutherland, R.L.5
Santen, R.J.6
Martin, L.A.7
Ciardiello, F.8
Miller, W.R.9
Dowsett, M.10
Barrett-Lee, P.11
Robertson, J.F.12
Johnston Jones, S.R.H.E.13
Wakeling, A.E.14
Duncan, R.15
Nicholson, R.I.16
-
30
-
-
33846890652
-
Deciphering antihormone-induced compensatory mechanisms in breast cancer and their therapeutic implications
-
Gee JM, Shaw VE, Hiscox SE, McClelland RA, Rushmere NK, Nicholson RI (2006) Deciphering antihormone-induced compensatory mechanisms in breast cancer and their therapeutic implications. Endocr Relat Cancer 13:S77-S88
-
(2006)
Endocr Relat Cancer
, vol.13
-
-
Gee, J.M.1
Shaw, V.E.2
Hiscox, S.E.3
McClelland, R.A.4
Rushmere, N.K.5
Nicholson, R.I.6
-
31
-
-
0842347483
-
Lyn is a target gene for prostate cancer: Sequence-based inhibition induces regression of human tumour xenografts
-
Goldenberg-Furmanov M, Stein I, Pikarsky E, Rubin H, Kasem S, Wygoda M, Weinstein I, Reuveni H, Ben-Sasson SA (2004) Lyn is a target gene for prostate cancer: Sequence-based inhibition induces regression of human tumour xenografts. Cancer Res 64:1058-1066
-
(2004)
Cancer Res
, vol.64
, pp. 1058-1066
-
-
Goldenberg-Furmanov, M.1
Stein, I.2
Pikarsky, E.3
Rubin, H.4
Kasem, S.5
Wygoda, M.6
Weinstein, I.7
Reuveni, H.8
Ben-Sasson, S.A.9
-
32
-
-
0031877714
-
RhoE regulates actin cytoskeleton organization and cell migration
-
Guasch RM, Scambler P, Jones GE, Ridley AJ (1998) RhoE regulates actin cytoskeleton organization and cell migration. Mol Cell Biol 18:4761-4771
-
(1998)
Mol Cell Biol
, vol.18
, pp. 4761-4771
-
-
Guasch, R.M.1
Scambler, P.2
Jones, G.E.3
Ridley, A.J.4
-
33
-
-
17844398046
-
Molecular changes in tamoxifen-resistant breast cancer: Relationship between estrogen receptor, HER-2, and p38 mitogen-Activated protein kinase
-
Gutierrez MC, Detre S, Johnston S, Mohsin SK, Shou J, Allred DC, Schiff R, Osborne CK, Dowsett M (2005) Molecular changes in tamoxifen-resistant breast cancer: Relationship between estrogen receptor, HER-2, and p38 mitogen-Activated protein kinase. J Clin Oncol 23:2469-2476
-
(2005)
J Clin Oncol
, vol.23
, pp. 2469-2476
-
-
Gutierrez, M.C.1
Detre, S.2
Johnston, S.3
Mohsin, S.K.4
Shou, J.5
Allred, D.C.6
Schiff, R.7
Osborne, C.K.8
Dowsett, M.9
-
34
-
-
34948870439
-
Upregulation of CD44s and variants in anti-hormone resistant breast cancer cells
-
Harper ME, Smith C, Nicholson RI (2005) Upregulation of CD44s and variants in anti-hormone resistant breast cancer cells. Eur J Cancer 3:A71
-
(2005)
Eur J Cancer
, vol.3
-
-
Harper, M.E.1
Smith, C.2
Nicholson, R.I.3
-
35
-
-
38849173792
-
Vascular endothelial growth factor receptor-2 expression is down-regulated by 17beta-estradiol in MCF-7 breast cancer cells by estrogen receptor alpha/sp proteins
-
Higgins KJ, Liu S, Abdelrahim M, Vanderlaag K, Liu X, PorterW, Metz R, Safe S (2008) Vascular endothelial growth factor receptor-2 expression is down-regulated by 17beta-estradiol in MCF-7 breast cancer cells by estrogen receptor alpha/sp proteins. Mol Endocrinol 22:388-402
-
(2008)
Mol Endocrinol
, vol.22
, pp. 388-402
-
-
Higgins, K.J.1
Liu, S.2
Abdelrahim, M.3
Vanderlaag, K.4
Liu, X.5
PorterW Metz, R.6
Safe, S.7
-
36
-
-
4344705051
-
Tamoxifen resistance in breast cancer cells is accompanied by an enhanced motile & invasive phenotype: Inhibition by gefitinib (iressa, ZD1839
-
Hiscox S, Morgan L, Barrow D, Dutkowski C, Wakeling A, Nicholson RI (2004) Tamoxifen resistance in breast cancer cells is accompanied by an enhanced motile & invasive phenotype: Inhibition by gefitinib (iressa, ZD1839). Clin Exp Metastasis 21:201-212
-
(2004)
Clin Exp Metastasis
, vol.21
, pp. 201-212
-
-
Hiscox, S.1
Morgan, L.2
Barrow, D.3
Dutkowski, C.4
Wakeling, A.5
Nicholson, R.I.6
-
37
-
-
28844494352
-
Tamoxifen resistance in MCF7 cells promotes EMT-like behaviour and involves modulation of beta-catenin phosphorylation
-
Hiscox S, JiangWG, Obermeier K, Taylor K, Morgan L, Burmi R, Barrow D, Nicholson RI (2006a) Tamoxifen resistance in MCF7 cells promotes EMT-like behaviour and involves modulation of beta-catenin phosphorylation. Int J Cancer 118:290-301
-
(2006)
Int J Cancer
, vol.118
, pp. 290-301
-
-
Hiscox, S.1
Jiang, W.G.2
Obermeier, K.3
Taylor, K.4
Morgan, L.5
Burmi, R.6
Barrow, D.7
Nicholson, R.I.8
-
38
-
-
33846811714
-
Chronic exposure to fulvestrant promotes overexpression of the c-met receptor in breast cancer cells: Implications for tumour-stroma interactions
-
Hiscox S, Jordan NJ, Jiang W, Harper M, McClelland R, Smith C, Nicholson RI (2006b) Chronic exposure to fulvestrant promotes overexpression of the c-met receptor in breast cancer cells: Implications for tumour-stroma interactions. Endocr Relat Cancer 13:1085-1099
-
(2006)
Endocr Relat Cancer
, vol.13
, pp. 1085-1099
-
-
Hiscox, S.1
Jordan, N.J.2
Jiang, W.3
Harper, M.4
McClelland, R.5
Smith, C.6
Nicholson, R.I.7
-
39
-
-
84889959854
-
Tamoxifen promotes cellular invasion in intercellular-Adhesion deficient breast cancer cells
-
Hiscox S, Borley A, Barratt-Lee P, Jordan NJ, Gee J, Shaw V, McClelland R, Nicholson RI (2006c) Tamoxifen promotes cellular invasion in intercellular-Adhesion deficient breast cancer cells. J Steroid Biochem Mol Biol 76(1-5):154
-
(2006)
J Steroid Biochem Mol Biol
, vol.76
, Issue.1-5
, pp. 154
-
-
Hiscox, S.1
Borley, A.2
Barratt-Lee, P.3
Jordan, N.J.4
Gee, J.5
Shaw, V.6
McClelland, R.7
Nicholson, R.I.8
-
40
-
-
33745402375
-
Elevated src activity promotes cellular invasion and motility in tamoxifen resistant breast cancer cells
-
Hiscox S, Morgan L, Green TP, Barrow D, Gee J, Nicholson RI (2006d) Elevated src activity promotes cellular invasion and motility in tamoxifen resistant breast cancer cells. Breast Cancer Res Treat 97:263-274
-
(2006)
Breast Cancer Res Treat
, vol.97
, pp. 263-274
-
-
Hiscox, S.1
Morgan, L.2
Green, T.P.3
Barrow, D.4
Gee, J.5
Nicholson, R.I.6
-
41
-
-
84889962968
-
Combination therapy with AZD0530 and tamoxifen prevents acquired anti-oestrogen resistance in breast cancer cells
-
Hiscox S, Green TP, Smith C, James M, Jordan N, Nicholson RI (2007) Combination therapy with AZD0530 and tamoxifen prevents acquired anti-oestrogen resistance in breast cancer cells. Proc Am Assoc Can Res Molecular Targets and Cancer Therapeutics Meeting A231
-
(2007)
Proc Am Assoc Can Res Molecular Targets and Cancer Therapeutics Meeting
-
-
Hiscox, S.1
Green, T.P.2
Smith, C.3
James, M.4
Jordan, N.5
Nicholson, R.I.6
-
42
-
-
0037293531
-
Tamoxifen functions as a molecular agonist inducing cell cycle-Associated genes in breast cancer cells
-
Hodges LC, Cook JD, Lobenhofer EK, Li L, Bennett L, Bushel PR, Aldaz CM, Afshari CA, Walker CL (2003) Tamoxifen functions as a molecular agonist inducing cell cycle-Associated genes in breast cancer cells. Mol Cancer Res 1:300-311
-
(2003)
Mol Cancer Res
, vol.1
, pp. 300-311
-
-
Hodges, L.C.1
Cook, J.D.2
Lobenhofer, E.K.3
Li, L.4
Bennett, L.5
Bushel, P.R.6
Aldaz, C.M.7
Afshari, C.A.8
Walker, C.L.9
-
43
-
-
2542454563
-
A cytoplasmic substrate of mitogen-Activated protein kinase is responsible for estrogen receptor-Alpha down-regulation in breast cancer cells: The role of nuclear factor-b
-
Holloway JN, Murthy S, El-Ashry D (2004) A cytoplasmic substrate of mitogen-Activated protein kinase is responsible for estrogen receptor-Alpha down-regulation in breast cancer cells: The role of nuclear factor-b. Mol Endocrinol 18:1396-1410
-
(2004)
Mol Endocrinol
, vol.18
, pp. 1396-1410
-
-
Holloway, J.N.1
Murthy, S.2
El-Ashry, D.3
-
44
-
-
32544448788
-
Fulvestrant (faslodex): Current and future role in breast cancer management
-
Howell A (2006) Fulvestrant (faslodex): Current and future role in breast cancer management. Crit Rev Oncol Hematol 57:265-273
-
(2006)
Crit Rev Oncol Hematol
, vol.57
, pp. 265-273
-
-
Howell, A.1
-
45
-
-
36549089022
-
Heregulin beta1 drives gefitinib-resistant growth and invasion in tamoxifen-resistant MCF-7 breast cancer cells
-
Hutcheson IR, Knowlden JM, Hiscox SE, Barrow D, Gee JM, Robertson JF, Ellis IO, Nicholson RI (2007) Heregulin beta1 drives gefitinib-resistant growth and invasion in tamoxifen-resistant MCF-7 breast cancer cells. Breast Cancer Res 9:R50
-
(2007)
Breast Cancer Res
, vol.9
-
-
Hutcheson, I.R.1
Knowlden, J.M.2
Hiscox, S.E.3
Barrow, D.4
Gee, J.M.5
Robertson, J.F.6
Ellis, I.O.7
Nicholson, R.I.8
-
46
-
-
0036803020
-
Development of cDNA microarray for expression profiling of estrogen-responsive genes
-
Inoue A, Yoshida N, Omoto Y, Oguchi S, Yamori T, Kiyama R, Hayashi S (2002) Development of cDNA microarray for expression profiling of estrogen-responsive genes. J Mol Endocrinology 29:175-192
-
(2002)
J Mol Endocrinology
, vol.29
, pp. 175-192
-
-
Inoue, A.1
Yoshida, N.2
Omoto, Y.3
Oguchi, S.4
Yamori, T.5
Kiyama, R.6
Hayashi, S.7
-
47
-
-
38549147013
-
Enhancing endocrine response with novel targeted therapies: Why have the clinical trials to date failed to deliver on the preclinical promise
-
Johnston SR, Leary A, Martin LA, Smith IE, Dowsett M (2008) Enhancing endocrine response with novel targeted therapies: Why have the clinical trials to date failed to deliver on the preclinical promisé Cancer 112:710-717
-
(2008)
Cancer
, vol.112
, pp. 710-717
-
-
Johnston, S.R.1
Leary, A.2
Martin, L.A.3
Smith, I.E.4
Dowsett, M.5
-
48
-
-
0032960181
-
Cancer epigenetics comes of age
-
Jones PA, Laird PW (1999) Cancer epigenetics comes of age. Nat Genet 21:163-167
-
(1999)
Nat Genet
, vol.21
, pp. 163-167
-
-
Jones, P.A.1
Laird, P.W.2
-
49
-
-
19944427176
-
Insulin-like growth factor-i receptor signalling and acquired resistance to gefitinib (zd1839; iressa) in human breast and prostate cancer cells
-
Jones HE, Goddard L, Gee JM, Hiscox S, Rubini M, Barrow D, Knowlden JM, Williams S, Wakeling AE, Nicholson RI (2004) Insulin-like growth factor-I receptor signalling and acquired resistance to gefitinib (ZD1839; iressa) in human breast and prostate cancer cells. Endocr Relat Cancer 11:793-814
-
(2004)
Endocr Relat Cancer
, vol.11
, pp. 793-814
-
-
Jones, H.E.1
Goddard, L.2
Gee, J.M.3
Hiscox, S.4
Rubini, M.5
Barrow, D.6
Knowlden, J.M.7
Williams, S.8
Wakeling, A.E.9
Nicholson, R.I.10
-
50
-
-
43949106182
-
Estrogenmediated downregulation of CD24 in breast cancer cells
-
Kaipparettu BA, Malik S, Konduri SD, LiuW, RokavecM, van der Kuip H, Hoppe R, Hammerich-Hille S, Fritz P, Schroth W, Abele I, Das GM, Oesterreich S, Brauch H (2008) Estrogenmediated downregulation of CD24 in breast cancer cells. Int J Cancer 123:66-72
-
(2008)
Int J Cancer
, vol.123
, pp. 66-72
-
-
Kaipparettu, B.A.1
Malik, S.2
Konduri, S.D.3
LiuW, RokavecM.4
Van Der Kuip, H.5
Hoppe, R.6
Hammerich-Hille, S.7
Fritz, P.8
Schroth, W.9
Abele, I.10
Das, G.M.11
Oesterreich, S.12
Brauch, H.13
-
51
-
-
13944252475
-
Transcription factor cross-Talk: The estrogen receptor and nfkappab
-
Kalaitzidis D, Gilmore TD (2005) Transcription factor cross-Talk: The estrogen receptor and NFkappaB. Trends Endocrinol Metab 16:46-52
-
(2005)
Trends Endocrinol Metab
, vol.16
, pp. 46-52
-
-
Kalaitzidis, D.1
Gilmore, T.D.2
-
52
-
-
0035127192
-
Change in expression of ER, bcl-2 and MIB1 on primary tamoxifen and relation to response in ER positive breast cancer
-
Kenny FS, Willsher PC, Gee JM, Nicholson R, Pinder SE, Ellis IO, Robertson JF (2001) Change in expression of ER, bcl-2 and MIB1 on primary tamoxifen and relation to response in ER positive breast cancer. Breast Cancer Res Treat 65:135-144
-
(2001)
Breast Cancer Res Treat
, vol.65
, pp. 135-144
-
-
Kenny, F.S.1
Willsher, P.C.2
Gee, J.M.3
Nicholson, R.4
Pinder, S.E.5
Ellis, I.O.6
Robertson, J.F.7
-
53
-
-
39449114233
-
B-RAF regulation of rnd3 participates in actin cytoskeletal and focal adhesion organization
-
Klein RM, Spofford LS, Abel EV, Ortiz A, Aplin AE (2008) B-RAF regulation of rnd3 participates in actin cytoskeletal and focal adhesion organization. Mol Biol Cell 19:498-508
-
(2008)
Mol Biol Cell
, vol.19
, pp. 498-508
-
-
Klein, R.M.1
Spofford, L.S.2
Abel, E.V.3
Ortiz, A.4
Aplin, A.E.5
-
54
-
-
0037373326
-
Elevated levels of epidermal growth factor receptor/c-erbB2 heterodimers mediate an autocrine growth regulatory pathway in tamoxifen-resistantMCF-7 cells
-
Knowlden JM, Hutcheson IR, Jones HE, Madden T, Gee JM, Harper ME, Barrow D, Wakeling AE, Nicholson RI (2003) Elevated levels of epidermal growth factor receptor/c-erbB2 heterodimers mediate an autocrine growth regulatory pathway in tamoxifen-resistantMCF-7 cells. Endocrinology 144:1032-1044
-
(2003)
Endocrinology
, vol.144
, pp. 1032-1044
-
-
Knowlden, J.M.1
Hutcheson, I.R.2
Jones, H.E.3
Madden, T.4
Gee, J.M.5
Harper, M.E.6
Barrow, D.7
Wakeling, A.E.8
Nicholson, R.I.9
-
55
-
-
26844487041
-
Insulin-like growth factori receptor signalling in tamoxifen-resistant breast cancer: A supporting role to the epidermal growth factor receptor
-
Knowlden JM, Hutcheson IR, Barrow D, Gee JM, Nicholson RI (2005) Insulin-like growth factori receptor signalling in tamoxifen-resistant breast cancer: A supporting role to the epidermal growth factor receptor. Endocrinology 146:4609-4618
-
(2005)
Endocrinology
, vol.146
, pp. 4609-4618
-
-
Knowlden, J.M.1
Hutcheson, I.R.2
Barrow, D.3
Gee, J.M.4
Nicholson, R.I.5
-
56
-
-
11744282298
-
Diverse signalling pathways modulate nuclear receptor recruitment of N-CoR and SMRT complexes
-
Lavinsky RM, Jepsen K, Heinzel T, Torchia J, Mullen TM, Schiff R, Del-Rio AL, Ricote M, Ngo S, Gemsch J, Hilsenbeck SG, Osborne CK, Glass CK, Rosenfeld MG, Rose DW (1998) Diverse signalling pathways modulate nuclear receptor recruitment of N-CoR and SMRT complexes. Proc Natl Acad Sci U S A 95:2920-2925
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 2920-2925
-
-
Lavinsky, R.M.1
Jepsen, K.2
Heinzel, T.3
Torchia, J.4
Mullen, T.M.5
Schiff, R.6
Del-Rio, A.L.7
Ricote, M.8
Ngo, S.9
Gemsch, J.10
Hilsenbeck, S.G.11
Osborne, C.K.12
Glass, C.K.13
Rosenfeld, M.G.14
Rose, D.W.15
-
57
-
-
0037068355
-
Molecular classification of selective oestrogen receptor modulators on the basis of gene expression profiles of breast cancer cells expressing oestrogen receptor alpha
-
Levenson AS, Kliakhandler IL, Svoboda KM, Pease KM, Kaiser SA, Ward JE 3rd, Jordan VC (2002a) Molecular classification of selective oestrogen receptor modulators on the basis of gene expression profiles of breast cancer cells expressing oestrogen receptor alpha. Br J Cancer 87:449-456
-
(2002)
Br J Cancer
, vol.87
, pp. 449-456
-
-
Levenson, A.S.1
Kliakhandler, I.L.2
Svoboda, K.M.3
Pease, K.M.4
Kaiser, S.A.5
Ward III, J.E.6
Jordan, V.C.7
-
58
-
-
0036682426
-
Gene expression profiles with activation of the estrogen receptor alphaselective estrogen receptor modulator complex in breast cancer cells expressing wild-Type estrogen receptor
-
Levenson AS, Svoboda KM, Pease KM, Kaiser SA, Chen B, Simons LA, Jovanovic BD, Dyck PA, Jordan VC (2002b) Gene expression profiles with activation of the estrogen receptor alphaselective estrogen receptor modulator complex in breast cancer cells expressing wild-Type estrogen receptor. Cancer Res 62:4419-4426
-
(2002)
Cancer Res
, vol.62
, pp. 4419-4426
-
-
Levenson, A.S.1
Svoboda, K.M.2
Pease, K.M.3
Kaiser, S.A.4
Chen, B.5
Simons, L.A.6
Jovanovic, B.D.7
Dyck, P.A.8
Jordan, V.C.9
-
59
-
-
8544226964
-
Loss of estrogen receptor signaling triggers epigenetic silencing of downstream targets in breast cancer
-
Leu YW, Yan PS, Fan M, Jin VX, Liu JC, Curran EM, Welshons WV, Wei SH, Davuluri RV, Plass C, Nephew KP, Huang TH (2004) Loss of estrogen receptor signaling triggers epigenetic silencing of downstream targets in breast cancer. Cancer Res 64:8184-8192
-
(2004)
Cancer Res
, vol.64
, pp. 8184-8192
-
-
Leu, Y.W.1
Yan, P.S.2
Fan, M.3
Jin, V.X.4
Liu, J.C.5
Curran, E.M.6
Welshons, W.V.7
Wei, S.H.8
Davuluri, R.V.9
Plass, C.10
Nephew, K.P.11
Huang, T.H.12
-
60
-
-
0037032835
-
The protein kinase complement of the human genome
-
Manning G, Whyte DB, Martinez R, Hunter T, Sudarsanam S (2002) The protein kinase complement of the human genome. Science 298:1912-1934
-
(2002)
Science
, vol.298
, pp. 1912-1934
-
-
Manning, G.1
Whyte, D.B.2
Martinez, R.3
Hunter, T.4
Sudarsanam, S.5
-
61
-
-
46749149722
-
Role of estrogens and their receptors in adhesion and invasiveness of breast cancer cells
-
Maynadier M, Nird́e P, Ramirez JM, Cathiard AM, Platet N, Chambon M, Garcia M (2008) Role of estrogens and their receptors in adhesion and invasiveness of breast cancer cells. Adv Exp Med Biol 617:485-491
-
(2008)
Adv Exp Med Biol
, vol.617
, pp. 485-491
-
-
Maynadier, M.1
Nird́e, P.2
Ramirez, J.M.3
Cathiard, A.M.4
Platet, N.5
Chambon, M.6
Garcia, M.7
-
62
-
-
0034987631
-
Enhanced epidermal growth factor receptor signalling in MCF-7 breast cancer cells after long-Term culture in the presence of the pure antiestrogen ICI 182,780 (faslodex
-
McClelland RA, Barrow D, Madden TA, Dutkowski CM, Pamment J, Knowlden JM, Gee JM, Nicholson RI (2001) Enhanced epidermal growth factor receptor signalling in MCF-7 breast cancer cells after long-Term culture in the presence of the pure antiestrogen ICI 182,780 (faslodex). Endocrinology 142:2776-2788
-
(2001)
Endocrinology
, vol.142
, pp. 2776-2788
-
-
McClelland, R.A.1
Barrow, D.2
Madden, T.A.3
Dutkowski, C.M.4
Pamment, J.5
Knowlden, J.M.6
Gee, J.M.7
Nicholson, R.I.8
-
63
-
-
0036179603
-
Trastuzumab: A review of its use in the treatment of metastatic breast cancer overexpressing HER2
-
McKeage K, Perry CM (2002) Trastuzumab: A review of its use in the treatment of metastatic breast cancer overexpressing HER2. Drugs 62:209-243
-
(2002)
Drugs
, vol.62
, pp. 209-243
-
-
McKeage, K.1
Perry, C.M.2
-
64
-
-
38749100194
-
Predicting response and resistance to endocrine therapy: Profiling patients on aromatase inhibitors
-
Miller WR, Larionov A, Anderson TJ, Walker JR, Krause A, Evans DB, Dixon JM (2008) Predicting response and resistance to endocrine therapy: Profiling patients on aromatase inhibitors. Cancer 112:689-694
-
(2008)
Cancer
, vol.112
, pp. 689-694
-
-
Miller, W.R.1
Larionov, A.2
Anderson, T.J.3
Walker, J.R.4
Krause, A.5
Evans, D.B.6
Dixon, J.M.7
-
65
-
-
23844517119
-
Diagnostic and therapeutic applications of epigenetics
-
Miyamoto K, Ushijima T (2005) Diagnostic and therapeutic applications of epigenetics. Jpn J Clin Oncol 35:293-301
-
(2005)
Jpn J Clin Oncol
, vol.35
, pp. 293-301
-
-
Miyamoto, K.1
Ushijima, T.2
-
66
-
-
33751315800
-
Reverting estrogen-receptor-negative phenotype in HER-2-overexpressing advanced breast cancer patients exposed to trastuzumab plus chemotherapy
-
Munzone E, Curigliano G, Rocca A, Bonizzi G, Renne G, Goldhirsch A, Nol̀e F (2006) Reverting estrogen-receptor-negative phenotype in HER-2-overexpressing advanced breast cancer patients exposed to trastuzumab plus chemotherapy. Breast Cancer Res 8:R4
-
(2006)
Breast Cancer Res
, vol.8
-
-
Munzone, E.1
Curigliano, G.2
Rocca, A.3
Bonizzi, G.4
Renne, G.5
Goldhirsch, A.6
Nol̀e, F.7
-
67
-
-
33646712747
-
Mechanisms of disease: Understanding resistance to HER2-Targeted therapy in human breast cancer
-
Nahta R, Yu D, Hung MC, Hortobagyi GN, Esteva FJ (2006) Mechanisms of disease: Understanding resistance to HER2-Targeted therapy in human breast cancer. Nat Clin Pract Oncol 3:269-280
-
(2006)
Nat Clin Pract Oncol
, vol.3
, pp. 269-280
-
-
Nahta, R.1
Yu, D.2
Hung, M.C.3
Hortobagyi, G.N.4
Esteva, F.J.5
-
68
-
-
0034719406
-
Cofactor competition between the ligand-bound oestrogen receptor and an intron 1 enhancer leads to oestrogen repression of ERBB2 expression in breast cancer
-
Newman SP, Bates NP, Vernimmen D, ParkerMG, Hurst HC (2000) Cofactor competition between the ligand-bound oestrogen receptor and an intron 1 enhancer leads to oestrogen repression of ERBB2 expression in breast cancer. Oncogene 19:490-497
-
(2000)
Oncogene
, vol.19
, pp. 490-497
-
-
Newman, S.P.1
Bates, N.P.2
Vernimmen, D.3
Parker, M.G.4
Hurst, H.C.5
-
70
-
-
11244250660
-
Growth factor-driven mechanisms associated with resistance to estrogen deprivation in breast cancer: New opportunities for therapy
-
Nicholson RI, Staka C, Boyns F, Hutcheson IR, Gee JM (2004) Growth factor-driven mechanisms associated with resistance to estrogen deprivation in breast cancer: New opportunities for therapy. Endocr Relat Cancer 11:623-641
-
(2004)
Endocr Relat Cancer
, vol.11
, pp. 623-641
-
-
Nicholson, R.I.1
Staka, C.2
Boyns, F.3
Hutcheson, I.R.4
Gee, J.M.5
-
71
-
-
25844458526
-
Growth factor signalling and resistance to selective oestrogen receptor modulators and pure anti-oestrogens: The use of anti-growth factor therapies to treat or delay endocrine resistance in breast cancer
-
Nicholson RI, Hutcheson IR, Hiscox SE, Knowlden JM, Giles M, Barrow D, Gee JM (2005) Growth factor signalling and resistance to selective oestrogen receptor modulators and pure anti-oestrogens: The use of anti-growth factor therapies to treat or delay endocrine resistance in breast cancer. Endocr Relat Cancer 12:S29-S36
-
(2005)
Endocr Relat Cancer
, vol.12
-
-
Nicholson, R.I.1
Hutcheson, I.R.2
Hiscox, S.E.3
Knowlden, J.M.4
Giles, M.5
Barrow, D.6
Gee, J.M.7
-
72
-
-
34948812466
-
Growth factor signalling in endocrine and anti-growth factor resistant breast cancer
-
Nicholson RI, Hutcheson IR, Jones HE, Hiscox SE, Giles M, Taylor KM, Gee JM (2007) Growth factor signalling in endocrine and anti-growth factor resistant breast cancer. Rev Endocr Metab Disord 8:241-253
-
(2007)
Rev Endocr Metab Disord
, vol.8
, pp. 241-253
-
-
Nicholson, R.I.1
Hutcheson, I.R.2
Jones, H.E.3
Hiscox, S.E.4
Giles, M.5
Taylor, K.M.6
Gee, J.M.7
-
73
-
-
29144526402
-
Mechanisms of endocrine resistance and novel therapeutic strategies in breast cancer
-
NCINaple Breast Cancer Group
-
Normanno N, Di Maio M, De Maio E, De Luca A, de Matteis A, Giordano A, Perrone F, NCINaple Breast Cancer Group (2005) Mechanisms of endocrine resistance and novel therapeutic strategies in breast cancer. Endocr Relat Cancer 12:721-747
-
(2005)
Endocr Relat Cancer
, vol.12
, pp. 721-747
-
-
Normanno, N.1
Di Maio, M.2
De Maio, E.3
De Luca, A.4
De Matteis, A.5
Giordano, A.6
Perrone, F.7
-
74
-
-
23644452485
-
Involvement of HP1alpha protein in irreversible transcriptional inactivation by antiestrogens in breast cancer cells
-
Oliva J, El Messaoudi S, Pellestor F, Fuentes M, Georget V, Balaguer P, Cavaill̀es V, Vignon F, Badia E (2005) Involvement of HP1alpha protein in irreversible transcriptional inactivation by antiestrogens in breast cancer cells. FEBS Lett 579:4278-4286
-
(2005)
FEBS Lett
, vol.579
, pp. 4278-4286
-
-
Oliva, J.1
El Messaoudi, S.2
Pellestor, F.3
Fuentes, M.4
Georget, V.5
Balaguer, P.6
Cavaill̀es, V.7
Vignon, F.8
Badia, E.9
-
75
-
-
0034464660
-
Unliganded and liganded estrogen receptors protect against cancer invasion via different mechanisms
-
Platet N, Cunat S, Chalbos D, Rochefort H, Garcia M (2000) Unliganded and liganded estrogen receptors protect against cancer invasion via different mechanisms. Molecular Endocrinol 14:999-1009
-
(2000)
Molecular Endocrinol
, vol.14
, pp. 999-1009
-
-
Platet, N.1
Cunat, S.2
Chalbos, D.3
Rochefort, H.4
Garcia, M.5
-
76
-
-
2942676455
-
Estrogens and their receptors in breast cancer progression: A dual role in cancer proliferation and invasion
-
Platet N, Cathiard AM, Gleizes M, Garcia M (2004) Estrogens and their receptors in breast cancer progression: A dual role in cancer proliferation and invasion. Critical Reviews Oncol/Hematol 51:55-67
-
(2004)
Critical Reviews Oncol/Hematol
, vol.51
, pp. 55-67
-
-
Platet, N.1
Cathiard, A.M.2
Gleizes, M.3
Garcia, M.4
-
78
-
-
33846861747
-
Targeting of multiple signalling pathways by heat shock protein 90 molecular chaperone inhibitors
-
Powers MV, Workman P (2006) Targeting of multiple signalling pathways by heat shock protein 90 molecular chaperone inhibitors. Endocr Relat Cancer 13:S125-S135
-
(2006)
Endocr Relat Cancer
, vol.13
-
-
Powers, M.V.1
Workman, P.2
-
79
-
-
0141619401
-
Estrogen withdrawal-induced NF-kappaB activity and bcl-3 expression in breast cancer cells: Roles in growth and hormone independence
-
Pratt MA, Bishop TE, White D, Yasvinski G, Menard M, Niu MY, Clarke R (2003) Estrogen withdrawal-induced NF-kappaB activity and bcl-3 expression in breast cancer cells: Roles in growth and hormone independence. Mol Cell Biol 23:6887-6900
-
(2003)
Mol Cell Biol
, vol.23
, pp. 6887-6900
-
-
Pratt, M.A.1
Bishop, T.E.2
White, D.3
Yasvinski, G.4
Menard, M.5
Niu, M.Y.6
Clarke, R.7
-
80
-
-
0038751849
-
Regulation of nuclear receptor transcriptional activity by a novel DEAD box RNA helicase (DP97
-
Rajendran RR, Nye AC, Frasor J, Balsara RD, Martini PG, Katzenellenbogen BS (2003) Regulation of nuclear receptor transcriptional activity by a novel DEAD box RNA helicase (DP97). J Biol Chem 278:4628-4638
-
(2003)
J Biol Chem
, vol.278
, pp. 4628-4638
-
-
Rajendran, R.R.1
Nye, A.C.2
Frasor, J.3
Balsara, R.D.4
Martini, P.G.5
Katzenellenbogen, B.S.6
-
81
-
-
20644472457
-
E-cadherin expression in invasive non-lobular carcinoma of the breast and its prognostic significance
-
Rakha EA, Abd El Rehim D, Pinder SE, Lewis SA, Ellis IO (2005) E-cadherin expression in invasive non-lobular carcinoma of the breast and its prognostic significance. Histopathology 46:685-693
-
(2005)
Histopathology
, vol.46
, pp. 685-693
-
-
Rakha, E.A.1
Abd El Rehim, D.2
Pinder, S.E.3
Lewis, S.A.4
Ellis, I.O.5
-
82
-
-
37149044202
-
Invasive lobular carcinoma of the breast: Response to hormonal therapy and outcomes
-
Rakha EA, El-Sayed ME, Powe DG, Green AR, Habashy H, Grainge MJ, Robertson JF, Blamey R, Gee J, Nicholson RI, Lee AH, Ellis IO (2008) Invasive lobular carcinoma of the breast: Response to hormonal therapy and outcomes. Eur J Cancer 44:73-83
-
(2008)
Eur J Cancer
, vol.44
, pp. 73-83
-
-
Rakha, E.A.1
El-Sayed, M.E.2
Powe, D.G.3
Green, A.R.4
Habashy, H.5
Grainge, M.J.6
Robertson, J.F.7
Blamey, R.8
Gee, J.9
Nicholson, R.I.10
Lee, A.H.11
Ellis, I.O.12
-
83
-
-
1642377561
-
Oncomine: A cancer microarray database and integrated data-mining platform
-
Rhodes DR, Yu J, Shanker K, Deshpande N, Varambally R, Ghosh D, Barrette T, Pandey A, Chinnaiyan AM (2004) ONCOMINE: A cancer microarray database and integrated data-mining platform. Neoplasia 6:1-6
-
(2004)
Neoplasia
, vol.6
, pp. 1-6
-
-
Rhodes, D.R.1
Yu, J.2
Shanker, K.3
Deshpande, N.4
Varambally, R.5
Ghosh, D.6
Barrette, T.7
Pandey, A.8
Chinnaiyan, A.M.9
-
85
-
-
13944282293
-
The nuclear factor kappa b inhibitor parthenolide restores ICI 182,780 (faslodex; fulvestrant)-induced apoptosis in antiestrogen-resistant breast cancer cells
-
Riggins RB, Zwart A, Nehra R, Clarke R (2005) The nuclear factor kappa b inhibitor parthenolide restores ICI 182,780 (faslodex; fulvestrant)-induced apoptosis in antiestrogen-resistant breast cancer cells. Mol Cancer Ther 4:33-41
-
(2005)
Mol Cancer Ther
, vol.4
, pp. 33-41
-
-
Riggins, R.B.1
Zwart, A.2
Nehra, R.3
Clarke, R.4
-
86
-
-
34948859553
-
Identification of anti-hormone induced genes as potential therapeutic targets in breast cancer
-
Shaw VE, Gee JMW, McClelland RA, Morgan H, Rushmere N, Nicholson RI (2005) Identification of anti-hormone induced genes as potential therapeutic targets in breast cancer. Proc Amer Assoc Cancer Res 46:A3706
-
(2005)
Proc Amer Assoc Cancer Res
, vol.46
-
-
Shaw, V.E.1
Gee, J.M.W.2
McClelland, R.A.3
Morgan, H.4
Rushmere, N.5
Nicholson, R.I.6
-
87
-
-
2942652871
-
Mechanisms of tamoxifen resistance: Increased estrogen receptor-HER2/neu cross-Talk in ER/HER2-positive breast cancer
-
Shou J, Massaraweh S, Osborne CK, Wakeling AE, Ali S, Weiss H, Schiff R (2004) Mechanisms of tamoxifen resistance: Increased estrogen receptor-HER2/neu cross-Talk in ER/HER2-positive breast cancer. J Natl Cancer Inst 96:926-935
-
(2004)
J Natl Cancer Inst
, vol.96
, pp. 926-935
-
-
Shou, J.1
Massaraweh, S.2
Osborne, C.K.3
Wakeling, A.E.4
Ali, S.5
Weiss, H.6
Schiff, R.7
-
88
-
-
25844519113
-
Acquired resistance to oestrogen deprivation: Role for growth factor signalling kinases/oestrogen receptor cross-Talk revealed in new MCF-7x model
-
Staka CM, Nicholson RI, Gee JM (2005) Acquired resistance to oestrogen deprivation: Role for growth factor signalling kinases/oestrogen receptor cross-Talk revealed in new MCF-7x model. Endocr Relat Cancer 12:S85-S97
-
(2005)
Endocr Relat Cancer
, vol.12
-
-
Staka, C.M.1
Nicholson, R.I.2
Gee, J.M.3
-
89
-
-
0029147741
-
Repression of the interleukin-6 promoter by estrogen receptor is mediated by NF-kappa b and C/EBP beta
-
Stein B, Yang MX (1995) Repression of the interleukin-6 promoter by estrogen receptor is mediated by NF-kappa b and C/EBP beta. Mol Cell Biol 15:4971-4979
-
(1995)
Mol Cell Biol
, vol.15
, pp. 4971-4979
-
-
Stein, B.1
Yang, M.X.2
-
90
-
-
84889965417
-
Anti-oestrogen therapy switches off tumour suppressors and proapoptotic genes in breast cancer and reveals a new therapeutic opportunity
-
Stone A, Jones H, Giles M, Gee J, Nicholson R (2008) Anti-oestrogen therapy switches off tumour suppressors and proapoptotic genes in breast cancer and reveals a new therapeutic opportunity. Breast Cancer Res 10:P41
-
(2008)
Breast Cancer Res
, vol.10
, pp. 41
-
-
Stone, A.1
Jones, H.2
Giles, M.3
Gee, J.4
Nicholson, R.5
-
91
-
-
33745188029
-
Estrogen-occupied estrogen receptor represses cyclin G2 gene expression and recruits a repressor complex at the cyclin G2 promoter
-
Stossi F, Likhite VS, Katzenellenbogen JA, Katzenellenbogen BS (2006) Estrogen-occupied estrogen receptor represses cyclin G2 gene expression and recruits a repressor complex at the cyclin G2 promoter. J Biol Chem 281:16272-16278
-
(2006)
J Biol Chem
, vol.281
, pp. 16272-16278
-
-
Stossi, F.1
Likhite, V.S.2
Katzenellenbogen, J.A.3
Katzenellenbogen, B.S.4
-
92
-
-
0032193220
-
Essential roles of lyn in fibronectin-mediated filamentous actin assembly and cell motility in mast cells
-
Suzuki T, Shoji S, Yamamoto K, Nada S, Okada M, Yamamoto T, Honda Z (1998) Essential roles of lyn in fibronectin-mediated filamentous actin assembly and cell motility in mast cells. J Immunol 161:3694-3701
-
(1998)
J Immunol
, vol.161
, pp. 3694-3701
-
-
Suzuki, T.1
Shoji, S.2
Yamamoto, K.3
Nada, S.4
Okada, M.5
Yamamoto, T.6
Honda, Z.7
-
94
-
-
4644243456
-
Tamoxifen long-Term treatment in vitro alters the apoptotic response of MCF-7 breast cancer cells
-
Treeck O, Zhou R, Diedrich K, Ortmann O (2004) Tamoxifen long-Term treatment in vitro alters the apoptotic response of MCF-7 breast cancer cells. Anticancer Drugs 15:787-793
-
(2004)
Anticancer Drugs
, vol.15
, pp. 787-793
-
-
Treeck, O.1
Zhou, R.2
Diedrich, K.3
Ortmann, O.4
-
95
-
-
0037421965
-
Blockage of heregulin expression inhibits tumorigenicity and metastasis of breast cancer
-
Tsai MS, Shamon-Taylor LA, Mehmi I, Tang CK, Lupu R (2003) Blockage of heregulin expression inhibits tumorigenicity and metastasis of breast cancer. Oncogene 22:761-768
-
(2003)
Oncogene
, vol.22
, pp. 761-768
-
-
Tsai, M.S.1
Shamon-Taylor, L.A.2
Mehmi, I.3
Tang, C.K.4
Lupu, R.5
-
96
-
-
0034682823
-
Mutations in the estrogen receptor ligand binding domain discriminate between hormone-dependent transactivation and transrepression
-
Valentine JE, Kalkhoven E, White R, Hoare S, Parker MG (2000) Mutations in the estrogen receptor ligand binding domain discriminate between hormone-dependent transactivation and transrepression. J Biol Chem 275:25322-25329
-
(2000)
J Biol Chem
, vol.275
, pp. 25322-25329
-
-
Valentine, J.E.1
Kalkhoven, E.2
White, R.3
Hoare, S.4
Parker, M.G.5
-
97
-
-
0028020839
-
Induction of estrogen independence of ZR-75-1 human breast cancer cells by epigenetic alterations
-
Van Agthoven T, van Agthoven TL, Dekker A, Foekens JA, Dorssers LC (1994) Induction of estrogen independence of ZR-75-1 human breast cancer cells by epigenetic alterations. Mol Endocrinol 8:1474-1483
-
(1994)
Mol Endocrinol
, vol.8
, pp. 1474-1483
-
-
Van Agthoven, T.1
Van Agthoven, T.L.2
Dekker, A.3
Foekens, J.A.4
Dorssers, L.C.5
-
99
-
-
0037068360
-
DNA methylation and breast carcinogenesis
-
Widschwendter M, Jones PA (2002) DNA methylation and breast carcinogenesis. Oncogene 21:5462-5482
-
(2002)
Oncogene
, vol.21
, pp. 5462-5482
-
-
Widschwendter, M.1
Jones, P.A.2
-
100
-
-
0036237676
-
Identification and characterization of a negative regulatory element within the epidermal growth factor receptor gene first intron in hormone-dependent breast cancer cells
-
Wilson MA, Chrysogelos SA (2002) Identification and characterization of a negative regulatory element within the epidermal growth factor receptor gene first intron in hormone-dependent breast cancer cells. J Cell Biochem 85:601-614
-
(2002)
J Cell Biochem
, vol.85
, pp. 601-614
-
-
Wilson, M.A.1
Chrysogelos, S.A.2
-
101
-
-
11844251170
-
The NF-kappaB/IkappaB signaling system: A molecular target in breast cancer therapy
-
Wu JT, Kral JG (2005) The NF-kappaB/IkappaB signaling system: A molecular target in breast cancer therapy. J Surg Res 123:158-169
-
(2005)
J Surg Res
, vol.123
, pp. 158-169
-
-
Wu, J.T.1
Kral, J.G.2
-
102
-
-
46849114097
-
Association between imatinib-resistant BCR-ABL mutationnegative leukemia and persistent activation of LYN kinase
-
Wu J, Meng F, Kong LY, Peng Z, Ying Y, Bornmann WG, Darnay BG, Lamothe B, Sun H, Talpaz M, Donato NJ (2008) Association between imatinib-resistant BCR-ABL mutationnegative leukemia and persistent activation of LYN kinase. J Natl Cancer Inst 100:926-939
-
(2008)
J Natl Cancer Inst
, vol.100
, pp. 926-939
-
-
Wu, J.1
Meng, F.2
Kong, L.Y.3
Peng, Z.4
Ying, Y.5
Bornmann, W.G.6
Darnay, B.G.7
Lamothe, B.8
Sun, H.9
Talpaz, M.10
Donato, N.J.11
-
103
-
-
37849047466
-
CtIP silencing as a novel mechanism of tamoxifen resistance in breast cancer
-
Wu M, Soler DR, Abba MC, NunezMI, Baer R, Hatzis C, Llombart-Cussac A, Llombart-Bosch A, Aldaz CM(2007) CtIP silencing as a novel mechanism of tamoxifen resistance in breast cancer. Mol Cancer Res 5:1285-1295
-
(2007)
Mol Cancer Res
, vol.5
, pp. 1285-1295
-
-
Wu, M.1
Soler, D.R.2
Abba, M.C.3
Nunez, M.I.4
Baer, R.5
Hatzis, C.6
Llombart-Cussac, A.7
Llombart-Bosch, A.8
Aldaz, C.M.9
-
104
-
-
0035036735
-
Estrogen suppression of EGFR expression in breast cancer cells: A possible mechanism to modulate growth
-
Yarden RI, Wilson MA, Chrysogelos SA (2001) Estrogen suppression of EGFR expression in breast cancer cells: A possible mechanism to modulate growth. J Cell Biochem 81:232-246
-
(2001)
J Cell Biochem
, vol.81
, pp. 232-246
-
-
Yarden, R.I.1
Wilson, M.A.2
Chrysogelos, S.A.3
-
105
-
-
58149295926
-
ERalpha suppresses slug expression directly by transcriptional repression
-
Ye Y, Xiao Y, WangW, Yearsley K, Gao JX, Barsky SH (2008) ERalpha suppresses slug expression directly by transcriptional repression. Biochem J 416(2):179-8
-
(2008)
Biochem J
, vol.416
, Issue.2
, pp. 179-188
-
-
Ye, Y.1
Xiao, Y.2
WangW Yearsley, K.3
Gao, J.X.4
Barsky, S.H.5
-
107
-
-
34247242607
-
Enhanced NF kappa b and AP-1 transcriptional activity associated with antiestrogen resistant breast cancer
-
Zhou Y, Yau C, Gray JW, Chew K, Dairkee SH, Moore DH, Eppenberger U, Eppenberger-Castori S, Benz CC (2007) Enhanced NF kappa b and AP-1 transcriptional activity associated with antiestrogen resistant breast cancer. BMC Cancer 7:59
-
(2007)
BMC Cancer
, vol.7
, pp. 59
-
-
Zhou, Y.1
Yau, C.2
Gray, J.W.3
Chew, K.4
Dairkee, S.H.5
Moore, D.H.6
Eppenberger, U.7
Eppenberger-Castori, S.8
Benz, C.C.9
-
108
-
-
21044436492
-
Estrogen-repressed genes-key mediators of estrogen action
-
Zubairy S, Oesterreich S (2005) Estrogen-repressed genes-key mediators of estrogen actioń Breast Cancer Res 7:163-16
-
(2005)
Breast Cancer Res
, vol.7
, pp. 163-126
-
-
Zubairy, S.1
Oesterreich, S.2
|