-
1
-
-
10744230036
-
Antiestrogen resistance in breast cancer and the role of estrogen receptor signaling
-
Clarke R, Liu MC, Bouker KB, et al. Antiestrogen resistance in breast cancer and the role of estrogen receptor signaling. Oncogene 2003; 22:7316-39.
-
(2003)
Oncogene
, vol.22
, pp. 7316-7339
-
-
Clarke, R.1
Liu, M.C.2
Bouker, K.B.3
-
3
-
-
0028861402
-
Response to a specific antioestrogen (ICI 182,780) in tamoxifen-resistant breast cancer
-
Howell A, DeFriend D, Robertson JFR, Blamey RW, Walton P. Response to a specific antioestrogen (ICI 182,780) in tamoxifen-resistant breast cancer. Lancet 1995;345:29-30.
-
(1995)
Lancet
, vol.345
, pp. 29-30
-
-
Howell, A.1
DeFriend, D.2
Robertson, J.F.R.3
Blamey, R.W.4
Walton, P.5
-
4
-
-
1842734250
-
Fulvestrant is an effective and well-tolerated endocrine therapy for postmenopausal women with advanced breast cancer: Results from clinical trials
-
Vergote I, Robertson JF. Fulvestrant is an effective and well-tolerated endocrine therapy for postmenopausal women with advanced breast cancer: results from clinical trials. Br J Cancer 2004;90:S11-4.
-
(2004)
Br. J. Cancer
, vol.90
-
-
Vergote, I.1
Robertson, J.F.2
-
5
-
-
0026560435
-
Antiestrogen ICI 164,384 reduces cellular estrogen receptor content by increasing its turnover
-
Dauvois S, Danielian PS, White R, Parker MG. Antiestrogen ICI 164,384 reduces cellular estrogen receptor content by increasing its turnover. Proc Natl Acad Sci U S A 1992;89:4037-41.
-
(1992)
Proc. Natl. Acad. Sci. U. S. A.
, vol.89
, pp. 4037-4041
-
-
Dauvois, S.1
Danielian, P.S.2
White, R.3
Parker, M.G.4
-
6
-
-
0025084510
-
Inhibition of estrogen receptor-DNA binding by the "pure" antiestrogen ICI 164,384 appears to be mediated by impaired receptor dimerization
-
Fawell SE, White R, Hoare S, Sydenham M, Page M, Parker MG. Inhibition of estrogen receptor-DNA binding by the "pure" antiestrogen ICI 164,384 appears to be mediated by impaired receptor dimerization. Proc Natl Acad Sci U S A 1990;87:6883-7.
-
(1990)
Proc. Natl. Acad. Sci. U. S. A.
, vol.87
, pp. 6883-6887
-
-
Fawell, S.E.1
White, R.2
Hoare, S.3
Sydenham, M.4
Page, M.5
Parker, M.G.6
-
7
-
-
0023701360
-
Novel antioestrogens without partial agonist activity
-
Wakeling AE, Bowler J. Novel antioestrogens without partial agonist activity. J Steroid Biochem 1988;31:645-53.
-
(1988)
J. Steroid. Biochem.
, vol.31
, pp. 645-653
-
-
Wakeling, A.E.1
Bowler, J.2
-
8
-
-
0035101145
-
Cellular and molecular pharmacology of antiestrogen action and resistance
-
Clarke R, Leonessa F, Welch JN, Skaar TC. Cellular and molecular pharmacology of antiestrogen action and resistance. Pharmacol Rev 2001;53:25-71.
-
(2001)
Pharmacol. Rev.
, vol.53
, pp. 25-71
-
-
Clarke, R.1
Leonessa, F.2
Welch, J.N.3
Skaar, T.C.4
-
9
-
-
0032537396
-
Tamoxifen for early breast cancer: An overview of the randomized trials
-
Early Breast Cancer Trialists' Collaborative Group
-
Early Breast Cancer Trialists' Collaborative Group, Tamoxifen for early breast cancer: an overview of the randomized trials. Lancet 1998;351: 1451-67.
-
(1998)
Lancet
, vol.351
, pp. 1451-1467
-
-
-
10
-
-
18544396176
-
Association of interferon regulatory factor-1, nucleophosmin, nuclear factor-κB, and cyclic AMP response element binding with acquired resistance to faslodex (ICI 182,780)
-
Gu Z, Lee RY, Skaar TC, et al. Association of interferon regulatory factor-1, nucleophosmin, nuclear factor-κB, and cyclic AMP response element binding with acquired resistance to faslodex (ICI 182,780). Cancer Res 2002;62:3428-37.
-
(2002)
Cancer Res.
, vol.62
, pp. 3428-3437
-
-
Gu, Z.1
Lee, R.Y.2
Skaar, T.C.3
-
11
-
-
15644377090
-
MCF7/LCC9: An antiestrogen resistant MCF-7 variant in which acquired resistance to the steroidal antiestrogen ICI 182,780 confers an early crossresistance to the non-steroidal antiestrogen tamoxifen
-
Brünner N, Boysen B, Jirus S, et al. MCF7/LCC9: an antiestrogen resistant MCF-7 variant in which acquired resistance to the steroidal antiestrogen ICI 182,780 confers an early crossresistance to the non-steroidal antiestrogen tamoxifen. Cancer Res 1997;57:3486-93.
-
(1997)
Cancer Res.
, vol.57
, pp. 3486-3493
-
-
Brünner, N.1
Boysen, B.2
Jirus, S.3
-
12
-
-
0027400210
-
Acquisition of hormone-independent growth in MCF-7 cells is accompanied by increased expression of estrogen-regulated genes but without detectable DNA amplifications
-
Brünner N, Boulay V, Fojo A, Freter C, Lippman ME, Clarke R. Acquisition of hormone-independent growth in MCF-7 cells is accompanied by increased expression of estrogen-regulated genes but without detectable DNA amplifications. Cancer Res 1993;53:283-90.
-
(1993)
Cancer Res.
, vol.53
, pp. 283-290
-
-
Brünner, N.1
Boulay, V.2
Fojo, A.3
Freter, C.4
Lippman, M.E.5
Clarke, R.6
-
13
-
-
2542531457
-
Interferon regulatory factor-1 mediates the proapoptotic but not cell cycle arrest effects of the steroidal antiestrogen ICI 182,780 (Faslodex, Fulvestrant)
-
Bouker KB, Skaar TC, Fernandez DR, et al. Interferon regulatory factor-1 mediates the proapoptotic but not cell cycle arrest effects of the steroidal antiestrogen ICI 182,780 (Faslodex, Fulvestrant). Cancer Res 2004;64:4030-9.
-
(2004)
Cancer Res.
, vol.64
, pp. 4030-4039
-
-
Bouker, K.B.1
Skaar, T.C.2
Fernandez, D.R.3
-
14
-
-
0033546410
-
Interaction of interferon regulatory factor-1 and nuclear factor κB during activation of inducible nitric oxide synthase transcription
-
Saura M, Zaragoza C, Bao C, McMillan A, Lowenstein CJ. Interaction of interferon regulatory factor-1 and nuclear factor κB during activation of inducible nitric oxide synthase transcription. J Mol Biol 1999;289:459-71.
-
(1999)
J. Mol. Biol.
, vol.289
, pp. 459-471
-
-
Saura, M.1
Zaragoza, C.2
Bao, C.3
McMillan, A.4
Lowenstein, C.J.5
-
16
-
-
0033596126
-
Diverse agents act at multiple levels to inhibit the Rel/NF-κB signal transduction pathway
-
Epinat JC, Gilmore TD. Diverse agents act at multiple levels to inhibit the Rel/NF-κB signal transduction pathway. Oncogene 1999;18: 6896-909.
-
(1999)
Oncogene
, vol.18
, pp. 6896-6909
-
-
Epinat, J.C.1
Gilmore, T.D.2
-
17
-
-
0343765810
-
Sesquiterpene lactone containing Mexican Indian medicinal plants and pure sesquiterpene lactones as potent inhibitors of transcription factor NF-κB
-
Bork PM, Schmitz ML, Kuhnt M, Escher C, Heinrich M. Sesquiterpene lactone containing Mexican Indian medicinal plants and pure sesquiterpene lactones as potent inhibitors of transcription factor NF-κB. FEBS Lett 1997;402:85-90.
-
(1997)
FEBS Lett.
, vol.402
, pp. 85-90
-
-
Bork, P.M.1
Schmitz, M.L.2
Kuhnt, M.3
Escher, C.4
Heinrich, M.5
-
18
-
-
0001112989
-
The anti-inflammatory sesquiterpene lactone helenalin inhibits the transcription factor NF-κB by directly targeting p65
-
Lyss G, Knorre A, Schmidt TJ, Pahl HL, Merfort I. The anti-inflammatory sesquiterpene lactone helenalin inhibits the transcription factor NF-κB by directly targeting p65. J Biol Chem 1998;273: 33508-16.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 33508-33516
-
-
Lyss, G.1
Knorre, A.2
Schmidt, T.J.3
Pahl, H.L.4
Merfort, I.5
-
19
-
-
0037064097
-
GADD153-mediated anticancer effects of N-(4-hydroxyphenyl)retinamide on human hepatoma cells
-
Kim DG, You KR, Liu MJ, Choi YK, Won YS. GADD153-mediated anticancer effects of N-(4-hydroxyphenyl)retinamide on human hepatoma cells. J Biol Chem 2002;277:38930-8.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 38930-38938
-
-
Kim, D.G.1
You, K.R.2
Liu, M.J.3
Choi, Y.K.4
Won, Y.S.5
-
20
-
-
0034710539
-
Paclitaxel sensitivity of breast cancer cells with constitutively active NF-κB is enhanced by IκBα super-repressor and parthenolide
-
Patel NM, Nozaki S, Shortle NH, et al. Paclitaxel sensitivity of breast cancer cells with constitutively active NF-κB is enhanced by IκBα super-repressor and parthenolide. Oncogene 2000;19:4159-69.
-
(2000)
Oncogene
, vol.19
, pp. 4159-4169
-
-
Patel, N.M.1
Nozaki, S.2
Shortle, N.H.3
-
21
-
-
3543018495
-
Phase I dose escalation trial of feverfew with standardized doses of parthenolide in patients with cancer
-
Curry EA III, Murry DJ, Yoder C, et al. Phase I dose escalation trial of feverfew with standardized doses of parthenolide in patients with cancer. Invest New Drugs 2004;22:299-305.
-
(2004)
Invest. New Drugs
, vol.22
, pp. 299-305
-
-
Curry III, E.A.1
Murry, D.J.2
Yoder, C.3
-
22
-
-
0023752998
-
Randomised double-blind placebo-controlled trial of feverfew in migraine prevention
-
Murphy JJ, Heptinstall S, Mitchell JR. Randomised double-blind placebo-controlled trial of feverfew in migraine prevention. Lancet 1988;2:189-92.
-
(1988)
Lancet
, vol.2
, pp. 189-192
-
-
Murphy, J.J.1
Heptinstall, S.2
Mitchell, J.R.3
-
23
-
-
0035137882
-
Control of oncogenesis and cancer therapy resistance by the transcription factor NF-κB
-
Baldwin AS. Control of oncogenesis and cancer therapy resistance by the transcription factor NF-κB. J Clin Invest 2001; 107:241-6.
-
(2001)
J. Clin. Invest.
, vol.107
, pp. 241-246
-
-
Baldwin, A.S.1
-
24
-
-
0037112514
-
Protein kinase CK2 promotes aberrant activation of nuclear factor-κB, transformed phenotype, and survival of breast cancer cells
-
Romieu-Mourez R, Landesman-Bollag E, Seldin DC, Sonenshein GE. Protein kinase CK2 promotes aberrant activation of nuclear factor-κB, transformed phenotype, and survival of breast cancer cells. Cancer Res 2002;62:6770-8.
-
(2002)
Cancer Res.
, vol.62
, pp. 6770-6778
-
-
Romieu-Mourez, R.1
Landesman-Bollag, E.2
Seldin, D.C.3
Sonenshein, G.E.4
-
25
-
-
1842538759
-
Secretion of cytokines and growth factors as a general cause of constitutive NFκB activation in cancer
-
Lu T, Sathe SS, Swiatkowski SM, Hampole CV, Stark GR. Secretion of cytokines and growth factors as a general cause of constitutive NFκB activation in cancer. Oncogene 2004;23:2138-45.
-
(2004)
Oncogene
, vol.23
, pp. 2138-2145
-
-
Lu, T.1
Sathe, S.S.2
Swiatkowski, S.M.3
Hampole, C.V.4
Stark, G.R.5
-
26
-
-
0141619401
-
Estrogen withdrawal-induced NF-κB activity and bcl-3 expression in breast cancer cells: Roles in growth and hormone independence
-
Pratt MAC, Bishop TE, White D, et al. Estrogen withdrawal-induced NF-κB activity and bcl-3 expression in breast cancer cells: roles in growth and hormone independence. Mol Cell Biol 2003;23: 6887-900.
-
(2003)
Mol. Cell Biol.
, vol.23
, pp. 6887-6900
-
-
Pratt, M.A.C.1
Bishop, T.E.2
White, D.3
-
27
-
-
0030927167
-
Constitutive activation of NF-κB during progression of breast cancer to hormone-independent growth
-
Nakshatri H, Bhat-Nakshatri P, Martin DA, Goulet RJ, Sledge GW. Constitutive activation of NF-κB during progression of breast cancer to hormone-independent growth. Mol Cell Biol 1997;17:3629-39.
-
(1997)
Mol. Cell Biol.
, vol.17
, pp. 3629-3639
-
-
Nakshatri, H.1
Bhat-Nakshatri, P.2
Martin, D.A.3
Goulet, R.J.4
Sledge, G.W.5
-
28
-
-
0020530724
-
A detergent-trypsin method for the preparation of nuclei for flow cytometric DNA analysis
-
Vindelov LL, Christensen IJ, Nissen NI. A detergent-trypsin method for the preparation of nuclei for flow cytometric DNA analysis. Cytometry 1983;3:323-7.
-
(1983)
Cytometry
, vol.3
, pp. 323-327
-
-
Vindelov, L.L.1
Christensen, I.J.2
Nissen, N.I.3
-
29
-
-
0031905299
-
In vitro and in vivo interaction between cisplatin and topotecan in ovarian carcinoma systems
-
Romanelli S, Perego P, Pratesi G, Carenini N, Tortoreto M, Zunino F. In vitro and in vivo interaction between cisplatin and topotecan in ovarian carcinoma systems. Cancer Chemother Pharmacol 1998;41:385-90.
-
(1998)
Cancer Chemother. Pharmacol.
, vol.41
, pp. 385-390
-
-
Romanelli, S.1
Perego, P.2
Pratesi, G.3
Carenini, N.4
Tortoreto, M.5
Zunino, F.6
-
30
-
-
0442307969
-
IκB kinases: Key regulators of the NF-κB pathway
-
Yamamoto Y, Gaynor RB. IκB kinases: key regulators of the NF-κB pathway. Trends Biochem Sci 2004;29:72-9.
-
(2004)
Trends Biochem. Sci.
, vol.29
, pp. 72-79
-
-
Yamamoto, Y.1
Gaynor, R.B.2
-
31
-
-
0037332580
-
Tetrameric oligomerization of IκB kinase γ (IKKγ) is obligatory for IKK complex activity and NF-κB activation
-
Tegethoff S, Behlke J, Scheidereit C. Tetrameric oligomerization of IκB kinase γ (IKKγ) is obligatory for IKK complex activity and NF-κB activation. Mol Cell Biol 2003; 23:2029-41.
-
(2003)
Mol. Cell Biol.
, vol.23
, pp. 2029-2041
-
-
Tegethoff, S.1
Behlke, J.2
Scheidereit, C.3
-
32
-
-
0036771830
-
The NF-κB signalling pathway in human diseases: From incontinentia pigmenti to ectodermal dysplasias and immune-deficiency syndromes
-
Smahi A, Courtois G, Rabia SH, et al. The NF-κB signalling pathway in human diseases: from incontinentia pigmenti to ectodermal dysplasias and immune-deficiency syndromes. Hum Mol Genet 2002; 11:2371-5.
-
(2002)
Hum. Mol. Genet.
, vol.11
, pp. 2371-2375
-
-
Smahi, A.1
Courtois, G.2
Rabia, S.H.3
-
33
-
-
0034745222
-
NF-κB stimulates inducible nitric oxide synthase to protect mouse hepatocytes from TNF-α- and Fas-mediated apoptosis
-
Hatano E, Bennett BL, Manning AM, Gian T, Lemasters JJ, Brenner DA. NF-κB stimulates inducible nitric oxide synthase to protect mouse hepatocytes from TNF-α- and Fas-mediated apoptosis. Gastroenterology 2001;120:1251-62.
-
(2001)
Gastroenterology
, vol.120
, pp. 1251-1262
-
-
Hatano, E.1
Bennett, B.L.2
Manning, A.M.3
Gian, T.4
Lemasters, J.J.5
Brenner, D.A.6
-
34
-
-
0036633164
-
Constitutive and inducible Akt activity promotes resistance to chemotherapy, trastuzumab, or tamoxifen in breast cancer cells
-
Clark AS, West K, Streicher S, Dennis PA. Constitutive and inducible Akt activity promotes resistance to chemotherapy, trastuzumab, or tamoxifen in breast cancer cells. Mol Cancer Ther 2002;1:707-17.
-
(2002)
Mol. Cancer Ther.
, vol.1
, pp. 707-717
-
-
Clark, A.S.1
West, K.2
Streicher, S.3
Dennis, P.A.4
-
35
-
-
0348016327
-
Cell cycle effects and caspase-dependent and independent death of HL-60 and Jurkat cells treated with the inhibitor of NF-κB parthenolide
-
Pozarowski P, Halicka DH, Darzynkiewicz Z. Cell cycle effects and caspase-dependent and independent death of HL-60 and Jurkat cells treated with the inhibitor of NF-κB parthenolide. Cell Cycle 2003; 2: 377-83.
-
(2003)
Cell Cycle
, vol.2
, pp. 377-383
-
-
Pozarowski, P.1
Halicka, D.H.2
Darzynkiewicz, Z.3
-
36
-
-
0031915368
-
Sesquiterpene lactones specifically inhibit activation of NF-κB by preventing the degradation of IκB-α and IκB-β
-
Hehner SP, Heinrich M, Bork PM, et al. Sesquiterpene lactones specifically inhibit activation of NF-κB by preventing the degradation of IκB-α and IκB-β. J Biol Chem 1998; 273:1288-97.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 1288-1297
-
-
Hehner, S.P.1
Heinrich, M.2
Bork, P.M.3
-
37
-
-
0034284715
-
Selective inhibition of NF-κB activation by a peptide that blocks the interaction of NEMO with the IκB kinase complex
-
May MJ, D'Acquisto F, Madge LA, Glockner J, Pober JS, Ghosh S. Selective inhibition of NF-κB activation by a peptide that blocks the interaction of NEMO with the IκB kinase complex. Science 2000;289: 1550-4.
-
(2000)
Science
, vol.289
, pp. 1550-1554
-
-
May, M.J.1
D'Acquisto, F.2
Madge, L.A.3
Glockner, J.4
Pober, J.S.5
Ghosh, S.6
-
38
-
-
0034175632
-
Severe liver degeneration and lack of NF-κB activation in NEMO/IKKγ-deficient mice
-
Rudolph D, Yeh WC, Wakeham A, et al. Severe liver degeneration and lack of NF-κB activation in NEMO /IKKγ-deficient mice. Genes Dev 2000; 14:854-62.
-
(2000)
Genes Dev.
, vol.14
, pp. 854-862
-
-
Rudolph, D.1
Yeh, W.C.2
Wakeham, A.3
-
39
-
-
1842538832
-
Modifying NEMO
-
Hay RT. Modifying NEMO. Nat Cell Biol 2004;6:89-91.
-
(2004)
Nat. Cell Biol.
, vol.6
, pp. 89-91
-
-
Hay, R.T.1
-
40
-
-
0031916865
-
Cross-talk between nuclear factor-κB and the steroid hormone receptors: Mechanisms of mutual antagonism
-
McKay LI, Cidlowski JA. Cross-talk between nuclear factor-κB and the steroid hormone receptors: mechanisms of mutual antagonism. Mol Endocrinol 1998;12:45-56.
-
(1998)
Mol. Endocrinol.
, vol.12
, pp. 45-56
-
-
McKay, L.I.1
Cidlowski, J.A.2
-
41
-
-
3442901974
-
NF-κB inhibition markedly enhances sensitivity of resistant breast cancer tumor cells to tamoxifen
-
DeGraffenried LA, Chandrasekar B, Friedrichs WE, et al. NF-κB inhibition markedly enhances sensitivity of resistant breast cancer tumor cells to tamoxifen. Ann Oncol 2004;15:885-90.
-
(2004)
Ann. Oncol.
, vol.15
, pp. 885-890
-
-
DeGraffenried, L.A.1
Chandrasekar, B.2
Friedrichs, W.E.3
-
42
-
-
0036848107
-
Inhibition of LPS-induced p42/44 MAP kinase activation and iNOS/NO synthesis by parthenolide in rat primary microglial cells
-
Fiebich BL, Lieb K, Engels S, Heinrich M. Inhibition of LPS-induced p42/44 MAP kinase activation and iNOS/NO synthesis by parthenolide in rat primary microglial cells. J Neuroimmunol 2002; 132:18-24.
-
(2002)
J. Neuroimmunol.
, vol.132
, pp. 18-24
-
-
Fiebich, B.L.1
Lieb, K.2
Engels, S.3
Heinrich, M.4
-
43
-
-
0035955729
-
Cysteine 38 in p65/NF-κB plays a crucial role in DNA binding inhibition by sesquiterpene lactones
-
Garcia-Pineres AJ, Castro V, Mora G, et al. Cysteine 38 in p65/NF-κB plays a crucial role in DNA binding inhibition by sesquiterpene lactones. J Biol Chem 2001;276:39713-20.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 39713-39720
-
-
Garcia-Pineres, A.J.1
Castro, V.2
Mora, G.3
-
44
-
-
6044240634
-
Antitumor agent parthenolide reverses resistance of breast cancer cells to tumor necrosis factor-related apoptosis-inducing ligand through sustained activation of c-Jun N-terminal kinase
-
Nakshatri H, Rice SE, Bhat-Nakshatri P. Antitumor agent parthenolide reverses resistance of breast cancer cells to tumor necrosis factor-related apoptosis-inducing ligand through sustained activation of c-Jun N-terminal kinase. Oncogene 2004;23:7330-44.
-
(2004)
Oncogene
, vol.23
, pp. 7330-7344
-
-
Nakshatri, H.1
Rice, S.E.2
Bhat-Nakshatri, P.3
-
45
-
-
0032990502
-
Low concentrations of the feverfew component parthenolide inhibit in vitro growth of tumor lines in a cytostatic fashion
-
Ross JJ, Arnason JT, Birnboim HC. Low concentrations of the feverfew component parthenolide inhibit in vitro growth of tumor lines in a cytostatic fashion. Planta Med 1999;65:126-9.
-
(1999)
Planta Med.
, vol.65
, pp. 126-129
-
-
Ross, J.J.1
Arnason, J.T.2
Birnboim, H.C.3
|