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Volumn 62, Issue 1, 2002, Pages 209-243

Trastuzumab: A review of its use in the treatment of metastatic breast cancer overexpressing HER2

Author keywords

Metastatic breast cancer; Monoclonal antibody; Pharmacodynamics; Pharmacokinetics; Therapeutic use

Indexed keywords

ALPHA INTERFERON; ANTHRACYCLINE; CISPLATIN; CYCLOPHOSPHAMIDE; DOXORUBICIN; GAMMA INTERFERON; PACLITAXEL; TRASTUZUMAB;

EID: 0036179603     PISSN: 00126667     EISSN: None     Source Type: Journal    
DOI: 10.2165/00003495-200262010-00008     Document Type: Review
Times cited : (260)

References (84)
  • 6
    • 0033368153 scopus 로고    scopus 로고
    • Trastuzumab, a humanized anti-HER2 monoclonal antibody, for the treatment of breast cancer
    • (1999) Drugs Today , vol.35 , Issue.12 , pp. 931-946
    • Albanell, J.1    Baselga, J.2
  • 11
    • 0035869520 scopus 로고    scopus 로고
    • From the molecule to the clinic - Inhibiting HER2 to treat breast cancer
    • Mar 15
    • (2001) N Engl J Med , vol.344 , Issue.11 , pp. 841-842
    • Eisenhauer, E.A.1
  • 13
    • 0035874981 scopus 로고    scopus 로고
    • Trastuzumab (Herceptin), a humanized anti-HER2 receptor monoclonal antibody, inhibits basal and activated HER2 ectodomain cleavage in breast cancer cells
    • Jun 15
    • (2001) Cancer Res , vol.61 , Issue.12 , pp. 4744-4749
    • Molina, M.A.1    Codony-Servat, J.2    Albanell, J.3
  • 14
    • 0032127350 scopus 로고    scopus 로고
    • Recombinant humanized anti-HER2 antibody (Herceptin®) enhances the antitumor activity of paclitaxel and doxorubicin against HER2/neu overexpressing human breast cancer xenografts
    • Jul 1
    • (1998) Cancer Res , vol.58 , pp. 2825-2831
    • Baselga, J.1    Norton, L.2    Albanell, J.3
  • 15
    • 0033118889 scopus 로고    scopus 로고
    • Inhibitory effects of combinations of HER-2/neu antibody and chemotherapeutic agents used for treatment of human breast cancers
    • Apr 1
    • (1999) Oncogene , vol.18 , pp. 2241-2251
    • Pegram, M.1    Hsu, S.2    Lewis, G.3
  • 23
    • 0033986779 scopus 로고    scopus 로고
    • Anti-HER2 antibody enhances the growth inhibitory effect of anti-oestrogen on breast cancer cells expressing both oestrogen receptors and HER2
    • Jan
    • (2000) Br J Cancer , vol.82 , Issue.1 , pp. 46-51
    • Kunisue, H.1    Kurebayashi, J.2    Otsuki, T.3
  • 26
    • 0032713216 scopus 로고    scopus 로고
    • Dose escalation and pharmacokinetic study of a humanized anti-HER2 monoclonal antibody in patients with HER2/neu-overexpressing metastatic breast cancer
    • Dec
    • (1999) Br J Cancer , vol.81 , pp. 1419-1425
    • Tokuda, Y.1    Watanabe, T.2    Omuro, Y.3
  • 31
    • 0031903646 scopus 로고    scopus 로고
    • HER2/neu monoclonal antibody plus cisplatin in patients with HER2/neu-overexpressing metastatic breast cancer refractory to chemotherapy treatment
    • Aug
    • (1998) J Clin Oncol , vol.16 , Issue.8 , pp. 2659-2671
    • Pegram, M.D.1    Lipton, A.2    Hayes, D.F.3
  • 35
    • 0035257923 scopus 로고    scopus 로고
    • Docetaxel (Taxotere) plus trastuzumab (Herceptin) in breast cancer
    • Feb
    • (2001) Semin Oncol , vol.28 , Issue.1 SUPPL. , pp. 38-44
    • Burris III, H.A.1
  • 39
    • 0002640818 scopus 로고    scopus 로고
    • Results of two open label multicentre phase II pilot studies with Herceptin in combination with docetaxel and platinum salts (Cis or Carboplatin) (TCH) as therapy for advanced breast cancer (ABC) in women with tumors over-expressing the HER2-neu proto-oncogene
    • Oct
    • (2001) Eur J Cancer , vol.37 , Issue.SUPPL. 6 , pp. 190
    • Nabholtz, J.M.1    Pienkowski, T.2    Nothfelt, D.3
  • 42
    • 0000498154 scopus 로고    scopus 로고
    • Capecitabine combined with trastuzumab in the therapy of intensively pretreated HER2-overexpressing metastatic breast cancer (MBC)
    • (2000) Ann Oncol , vol.11 , Issue.SUPPL. 4 , pp. 143
    • Bangemann, N.1    Kuhle, A.2    Ebert, A.3
  • 43
    • 0000864447 scopus 로고    scopus 로고
    • Taxotere, cisplatin and herceptin (TCH) in first-line HER2 positive metastatic breast cancer (MBC) patients, a phase II pilot study by the breast cancer international research group (BCIRG 101)
    • May 12; San Francisco, CA
    • (2001) Proc Am Soc Clin Oncol , vol.20 , Issue.PART 2
    • Pienkowski, T.1    Fumoleau, P.2    Eiermann, J.3
  • 44
    • 2042456082 scopus 로고    scopus 로고
    • A phase II multicenter trial of weekly herceptin with navelbine in chemonaive patients with her2 positive metastatic breast cancer
    • Oct 21
    • (2001) Eur J Cancer , vol.37 , Issue.SUPPL. 6 , pp. 194
    • Jahanzeb, M.1    Mortimer, J.2    Yunus, D.3
  • 45
    • 0032850677 scopus 로고    scopus 로고
    • Multinational study of the efficacy and safety of humanized anti-HER2 monoclonal antibody in women who have HER2-overexpressing metastatic breast cancer that has progressed after chemotherapy for metastatic disease
    • Sep
    • (1999) J Clin Oncol , vol.17 , pp. 2639-2648
    • Cobleigh, M.A.1    Vogel, C.L.2    Tripathy, D.3
  • 46
    • 0035873815 scopus 로고    scopus 로고
    • Weekly trastuzumab and paclitaxel therapy for metastatic breast cancer with analysis of efficacy by HER2 immunophenotype and gene amplification
    • May
    • (2001) J Clin Oncol , vol.19 , Issue.10 , pp. 2587-2595
    • Seidman, A.D.1    Fornier, M.N.2    Esteva, F.J.3
  • 53
    • 4243941287 scopus 로고    scopus 로고
    • Efficacy and safety of three weekly herceptin with paclitaxel in women with Her2-positive metastatic breast cancer: Preliminary results of a phase II trial
    • Oct 21
    • (2001) Ear J Cancer , vol.37 , Issue.SUPPL. 6
    • Verma, S.1    Leyland-Jones, B.2    Ayoub, J.-P.3
  • 54
    • 0037762061 scopus 로고    scopus 로고
    • Weekly (W) Herceptinr (H, Traztuximab) and one hour Taxol (T, paclitaxel) infusion (WHT) regimen for human epidermal growth factor receptor-2 (HER2) overexpressed (+) metastatic breast cancer (MBC)
    • May 20; New Orleans
    • (2000) Proc 36th Am Soc Clin Oncol , vol.19
    • Yeung, K.1    Gupta, R.2    Haidak, D.3
  • 55
    • 4244077645 scopus 로고    scopus 로고
    • Phase II study of weekly docetaxel (Taxotere; txt) and trastuzumab (Herceptin; H) for patients with HER-2 overexpressing (HER2+) metastatic breast cancer (MBC)
    • Oct 21
    • (2001) Eur J Cancer , vol.37 , Issue.SUPPL. 6
    • Esteva, F.J.1    Valero, V.2    Booser, D.3
  • 62
    • 0035873962 scopus 로고    scopus 로고
    • Discrepancies in clinical laboratory testing of eligibility for trastuzumab therapy: Apparent immunohistochemical false-positives do not get the message
    • May
    • (2001) J Clin Oncol , vol.19 , Issue.10 , pp. 2714-2721
    • Tubbs, R.R.1    Pettay, J.D.2    Roche, P.C.3
  • 63
    • 4243941286 scopus 로고    scopus 로고
    • Initial report of the HER2000 study: A multinational study of HER2 status of breast cancer using immunohistochemistry (IHC; Herceptest)
    • Oct 21
    • (2001) Eur J Cancer , vol.37 , Issue.SUPPL. 6
    • Acosta, G.1    Askaa, J.2    Bilous, M.3
  • 67
    • 0003277731 scopus 로고    scopus 로고
    • Effects of treatment with Her2mab (trastuzumab/Herceptin) plus chemotherapy (H+C) versus chemotherapy alone (C) on health-related quality of life (HRQL) in women with HER-2/neu-overexpressing metastatic breast cancer
    • May 12-15 San Francisco (CA)
    • (2001) Proc Am Soc Clin Oncol , vol.20 , Issue.PART 1 , pp. 28
    • Osoba, D.1    Slamon, D.J.2    Burchmore, M.3
  • 70
    • 0001137394 scopus 로고    scopus 로고
    • Cutaneous photosensitivity associated with abberations in the heme biosynthetic pathway induced by taxanes (T) and trastuzumab (H): A report of 3 cases of metastatic breast cancer
    • (2000) Ann Oncol , vol.11 , Issue.SUPPL. 4 , pp. 28
    • Mermershtain, W.1    Cohen, A.D.2    Geffen, D.B.3
  • 76
    • 0000228643 scopus 로고    scopus 로고
    • Cardiac safety of herceptin® in combination with epirubicin plus cyclophosphamide: Interim results of a phase II study in patients with metastatic breast cancer
    • Oct 21
    • (2001) Eur J Cancer , vol.37 , Issue.SUPPL. 6
    • Untch, M.1    Schaller, G.2    Jaenicke, F.3
  • 77
    • 2042516969 scopus 로고    scopus 로고
    • Cardiac safety and antitumor activity of doxorubicin and taxol followed by weekly taxol (AT & T) when herceptin is initiated with AT or with T alone in women with HER2-positive advanced breast cancer
    • Oct 21
    • (2001) Eur J Cancer , vol.37 , Issue.SUPPL. 6
    • Gianni, L.1    Eiermann, W.2    Borquez, D.3
  • 81
    • 0034659774 scopus 로고    scopus 로고
    • Developments in chemotherapy of breast cancer
    • Jun 15
    • (2000) Cancer , vol.88 , Issue.12 SUPPL. , pp. 3073-3079
    • Hortobagyi, G.N.1
  • 84


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.