Antigen-independent induction of tim-3 expression on human T cells by the common γ-chain cytokines IL-2, IL-7, IL-15, and IL-21 is associated with proliferation and is dependent on the phosphoinositide 3-kinase pathway

Journal of Immunology

Volumn 188, Issue 8, 2012, Pages 3745-3756

  Mujib, Shariq ^a   Jones, R Brad ^a   Lo, Calvin ^a   Aidarus, Nasra ^a   Clayton, Kiera ^a   Sakhdari, Ali ^a   Benko, Erika ^b   Kovacs, Colin ^b   Ostrowski, Mario A ^a,c  

^a UNIVERSITY OF TORONTO   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c ST MICHAEL'S HOSPITAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; CD28 ANTIGEN; ECALECTIN; GLYCOPROTEIN; INTERLEUKIN 15; INTERLEUKIN 2; INTERLEUKIN 21; INTERLEUKIN 7; LIPOPOLYSACCHARIDE; PHOSPHATIDYLINOSITOL 3 KINASE; T CELL IMMUNOGLOBULIN MUCIN DOMAIN CONTAINING MOLECULE 3; T LYMPHOCYTE RECEPTOR; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CONTROLLED STUDY; EFFECTOR CELL; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1 INFECTION; LYMPHOCYTE PROLIFERATION; MEMORY T LYMPHOCYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; T LYMPHOCYTE; UPREGULATION;

ANTIGENS, CD28; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CELLS, CULTURED; CHROMONES; GALECTINS; GENE EXPRESSION REGULATION; HIV INFECTIONS; HIV-1; HUMANS; INTERLEUKIN-15; INTERLEUKIN-2; INTERLEUKIN-7; INTERLEUKINS; LYMPHOCYTE ACTIVATION; MEMBRANE PROTEINS; MORPHOLINES; PHOSPHATIDYLINOSITOL 3-KINASE; PROTEIN KINASE INHIBITORS; RECEPTORS, ANTIGEN, T-CELL; SIGNAL TRANSDUCTION;

EID: 84860330727     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1102609     Document Type: Article

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