The phosphatidylserine receptors, T cell immunoglobulin mucin proteins 3 and 4, are markers of histiocytic sarcoma and other histiocytic and dendritic cell neoplasms

Human Pathology

Volumn 41, Issue 10, 2010, Pages 1486-1494

  Dorfman, David M ^a,b   Hornick, Jason L ^a,b   Shahsafaei, Aliakbar ^a,b   Freeman, Gordon J ^b,c  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c DANA FARBER CANCER INSTITUTE   (United States)

Author keywords

Blastic plasmacytoid dendritic cell neoplasm; Follicular dendritic cell sarcoma; Interdigitating dendritic cell sarcoma; Juvenile xanthogranuloma; Langerhans cell histiocytosis; Leukemia cutis; T cell immunoglobulin mucin protein

Indexed keywords

MUCIN; PHOSPHATIDYLSERINE; PROTEIN TIM 3; PROTEIN TIM 4; UNCLASSIFIED DRUG; CELL SURFACE RECEPTOR; HAVCR2 PROTEIN, HUMAN; MEMBRANE PROTEIN; PHOSPHATIDYLSERINE RECEPTOR; TIMD4 PROTEIN, HUMAN; TUMOR MARKER;

ARTICLE; CELL DIFFERENTIATION; CONTROLLED STUDY; DENDRITIC CELL SARCOMA; HISTIOCYTIC SARCOMA; HISTIOCYTOSIS; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LARGE CELL LYMPHOMA; METASTASIS; T LYMPHOCYTE; ANTIBODY SPECIFICITY; DENDRITIC CELL; HISTIOCYTE; HISTIOCYTIC LYMPHOMA; METABOLISM; PATHOLOGY;

DENDRITIC CELLS; HISTIOCYTES; HISTIOCYTIC DISORDERS, MALIGNANT; HISTIOCYTIC SARCOMA; HUMANS; IMMUNOHISTOCHEMISTRY; MEMBRANE PROTEINS; ORGAN SPECIFICITY; RECEPTORS, CELL SURFACE; TUMOR MARKERS, BIOLOGICAL;

EID: 77957109628     PISSN: 00468177     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.humpath.2010.04.005     Document Type: Article

References (26)

1. Rodriguez-Manzanet R, DeKruyff R, Kuchroo V.K, and Umetsu D.T. The costimulatory role of TIM molecules Immunol Rev 229 2009 259 270
2. Kobayashi N, Karisola P, and Pena-Cruz V. TIM-1 and TIM-4 glycoproteins bind phosphatidylserine and mediate uptake of apoptotic cells Immunity 27 2007 927 940
3. Golden-Mason L, Palmer B.E, and Kassam N. Negative immune regulator Tim-3 is overexpressed on T cells in hepatitis C virus infection and its blockade rescues dysfunctional CD4+ and CD8+T cells J Virol 83 18 2009 9122 9130
4. Nakayama M, AKiba H, and Takeda K. Tim-3 mediates phagocytosis of apoptotic cells and cross-presentation Blood 113 2009 3821 3830
5. DeKruyff R.H, Bu X, and Ballesteros A. TIM-3 allelic variants differentially recognize phosphatidylserine and mediate phagocytosis of apoptotic cells J Immunol 184 2010 1918 1930
6. Anderson A.C, Anderson D.E, and Bregoli L. Promotion of tissue inflammation by the immune receptor Tim-3 expressed on innate immune cells Science 318 5853 2007 1141 1143
7. Swerdlow S.H, Campo E, and Harris N.L. WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues 2008 IARC Press Lyon
8. Dorfman D.M, Greisman H.A, and Shahsafaei A. Loss of expression of the WNT/beta-catenin-signaling pathway transcription factors lymphoid enhancer factor-1 (LEF-1) and T cell factor (TCF-1) in a subset of peripheral T cell lymphomas Am J Pathol 162 2003 1539 1544
9. Dorfman D.M, Brown J.A, Shahsafaei A, and Freeman G.J. Programmed death-1 (PD-1) is a marker of germinal center-associated T cell and angioimmunoblastic T-cell lymphoma Am J Surg Pathol 30 2006 802 810
10. Weitzman S, and Jaffe R. Uncommon histiocytic disorders: the non-Langerhans cell histiocytoses Pediatr Blood Cancer 45 2005 256 264
11. Mills J.A, Gonzalez G, and Jaffe R. Case records of the Massachusetts General Hospital (Case 25-2008: a 43-year-old man with fatigue and lesion sin the pituitary and cerebellum N Engl J Med 359 2008 736 747
12. Munoz-Fernandez R, Blanco F.J, and Frecha C. Follicular dendritic cells are related to bone marrow stromal cell progenitors and to myofibroblasts J Immunol 177 2006 280 289
13. Lau S.K, Chu P.G, and Weiss L.M. Immunohistochemical expression of Langerin in Langerhans cell histiocytosis and non-Langerhans cell histiocytic disorders Am J Surg Pathol 32 2008 615 619
14. Hornick J.L, Jaffe E.S, and Fletcher C.D.M. Extranodal histiocytic sarcoma: clinicopathologic analysis of 14 cases of a rare epithelioid malignancy Am J Surg Pathol 28 2004 1133 1144
15. Yu H, Gibson J.A, Pinkus G.S, and Hornick J.L. Podoplanin (D2-40) is a novel marker for follicular dendritic cell tumors Am J Clin Pathol 128 2007 776 782
16. H17 cytokines Eur J Immunol 39 9 2009 2492 2501
17. Montecino-Rodriguez E, Leathers H, and Dorshkind K. Bipotential B-macrophage progenitors are present in adult bone marrow Nat Immunol 2 2001 83 88
18. Hou Y.H, Srour E.F, Ramsey H, Dahl R, Broxmeyer H.E, and Hromas R. Identification of a human B-cell/myeloid common progenitor by the absence of CXCR4 Blood 105 2005 3488 3492
19. Feldman A.L, Arber D.A, and Pittaluga S. Clonally related follicular lymphomas and histiocytic/dendritic cell sarcomas: evidence for transdifferentiation of the follicular lymphoma clone Blood 111 2008 5433 5439
20. Feldman A.L, Minniti C, Santi M, Downing J.R , Raffeld M, and Jaffe E.S. Histiocytic sarcoma after acute lymphoblastic leukemia: a common clonal origin Lancet Oncol 5 2004 248 250
21. Magni M, Di Nicola M, and Carlo-Stella C. Identical gene rearrangement of immunoglobulin heavy chain gene in neoplastic Langerhans cells and B-lymphocytes: evidence for a common precursor Leuk Res 26 2002 1131 1133
22. Xie H, Ye M, Feng R, and Graf T. Stepwise reprogramming of B cell into macrophages Cell 117 2004 663 676
23. Colbaleda C, Jochum W, and Busslinger M. Conversion of mature B cells into T cell by dedifferentiation to uncommitted progenitors Nature 449 2007 473 477
24. Paquette R.L, Hsu N, and Said J. Interferon-alpha induces dendritic cell differentiation of CML mononuclear cells in vitro and in vivo Leukemia 16 2002 1484 1489
25. Marafioti T, Ascani S, and Pulford K. Expression of B-lymphocyte- associated transcription factors in human T-cell neoplasms Am J Pathol 162 2003 861 871
26. Dorfman D.M, Hwang E.S, Shahsafaei A, and Glimcher L.H. T-bet, a T-cell-associated transcription factor, is expressed in a subset of B-cell lymphoproliferative disorders Am J Clin Pathol 122 2004 292 297