-
1
-
-
0037564560
-
Molecular modifiers of T cell antigen receptor triggering threshold: The mechanism of CD28 costimulatory receptor
-
Acuto O, Mise-Omata S, Mangino G, Michel F. Molecular modifiers of T cell antigen receptor triggering threshold: the mechanism of CD28 costimulatory receptor. Immunol Rev. 2003;192:21-31.
-
(2003)
Immunol Rev
, vol.192
, pp. 21-31
-
-
Acuto, O.1
Mise-Omata, S.2
Mangino, G.3
Michel, F.4
-
2
-
-
0032498231
-
-
Cell
-
Zhang W, Sloan-Lancaster J, Kitchen J, Trible RP, Samelson LE. LAT: the ZAP-70 tyrosine kinase substrate that links T cell receptor to cellular activation. Cell. 1998;92:83-92.
-
(1998)
LAT: The ZAP-70 tyrosine kinase substrate that links T cell receptor to cellular activation
, vol.92
, pp. 83-92
-
-
Zhang, W.1
Sloan-Lancaster, J.2
Kitchen, J.3
Trible, R.P.4
Samelson, L.E.5
-
3
-
-
0000082758
-
Phosphorylation of SLP-76 by the ZAP-70 protein- tyrosine kinase is required for T-cell receptor function
-
Bubeck Wardenburg J, Fu C, Jackman JK, et al. Phosphorylation of SLP-76 by the ZAP-70 protein- tyrosine kinase is required for T-cell receptor function. J Biol Chem. 1996;271:19641-19644.
-
(1996)
J Biol Chem
, vol.271
, pp. 19641-19644
-
-
Bubeck Wardenburg, J.1
Fu, C.2
Jackman, J.K.3
-
4
-
-
0029004651
-
Immediate-early genes induced by antigen receptor stimulation
-
Kelly K, Siebenlist U. Immediate-early genes induced by antigen receptor stimulation. Curr Opin Immunol. 1995;7:327-332.
-
(1995)
Curr Opin Immunol
, vol.7
, pp. 327-332
-
-
Kelly, K.1
Siebenlist, U.2
-
5
-
-
0036141994
-
Costimulation and endogenous MHC ligands contribute to T cell recognition
-
Wülfing C, Sumen C, Sjaastad MD, Wu LC, Dustin ML, Davis MM. Costimulation and endogenous MHC ligands contribute to T cell recognition. Nat Immunol. 2002;3:42-47.
-
(2002)
Nat Immunol
, vol.3
, pp. 42-47
-
-
Wülfing, C.1
Sumen, C.2
Sjaastad, M.D.3
Wu, L.C.4
Dustin, M.L.5
Davis, M.M.6
-
6
-
-
0030293443
-
CD28/B7 interactions deliver a unique signal to naive T cells that regulates cell survival but not early proliferation
-
Sperling AI, Auger JA, Ehst BD, Rulifson IC, Thompson CB, Bluestone JA. CD28/B7 interactions deliver a unique signal to naive T cells that regulates cell survival but not early proliferation. J Immunol. 1996;157:3909-3917.
-
(1996)
J Immunol
, vol.157
, pp. 3909-3917
-
-
Sperling, A.I.1
Auger, J.A.2
Ehst, B.D.3
Rulifson, I.C.4
Thompson, C.B.5
Bluestone, J.A.6
-
7
-
-
0030056468
-
-
Schwartz RH. Models of T cell anergy: is there a common molecular mechanism?. J Exp Med. 1996;184:1-8.
-
Schwartz RH. Models of T cell anergy: is there a common molecular mechanism?. J Exp Med. 1996;184:1-8.
-
-
-
-
9
-
-
0028178873
-
Signals and signs for lymphocyte responses
-
Janeway CA Jr, Bottomly K. Signals and signs for lymphocyte responses. Cell. 1994;76:275-285.
-
(1994)
Cell
, vol.76
, pp. 275-285
-
-
Janeway Jr, C.A.1
Bottomly, K.2
-
10
-
-
0037090337
-
Temporal segregation of 4-1BB versus CD28-mediated costimula- tion: 4-1BB ligand influences T cell numbers late in the primary response and regulates the size of the T cell memory response following influenza infection
-
Bertram EM, Lau P, Watts TH. Temporal segregation of 4-1BB versus CD28-mediated costimula- tion: 4-1BB ligand influences T cell numbers late in the primary response and regulates the size of the T cell memory response following influenza infection. J Immunol. 2002;168:3777-3785.
-
(2002)
J Immunol
, vol.168
, pp. 3777-3785
-
-
Bertram, E.M.1
Lau, P.2
Watts, T.H.3
-
11
-
-
0036075444
-
In vivo stimulation of CD137 broadens primary antiviral CD8+ T cell responses
-
Halstead ES, Mueller YM, Altman JD, Katsikis PD. In vivo stimulation of CD137 broadens primary antiviral CD8+ T cell responses. Nat Immunol. 2002;3:536-541.
-
(2002)
Nat Immunol
, vol.3
, pp. 536-541
-
-
Halstead, E.S.1
Mueller, Y.M.2
Altman, J.D.3
Katsikis, P.D.4
-
12
-
-
0035889910
-
Role of CD28 for the generation and expansion of antigen-specific CD8(+) T lymphocytes during infection with Listeria monocytogenes
-
Mittrucker HW, Kursar M, Kohler A, Hurwitz R, Kaufmann SH. Role of CD28 for the generation and expansion of antigen-specific CD8(+) T lymphocytes during infection with Listeria monocytogenes. J Immunol. 2001;167:5620-5627.
-
(2001)
J Immunol
, vol.167
, pp. 5620-5627
-
-
Mittrucker, H.W.1
Kursar, M.2
Kohler, A.3
Hurwitz, R.4
Kaufmann, S.H.5
-
13
-
-
0035889949
-
Role of CD28-B7 interactions in generation and maintenance of CD8 Tcell memory
-
Suresh M, Whitmire JK, Harrington LE, et al. Role of CD28-B7 interactions in generation and maintenance of CD8 Tcell memory. J Immunol. 2001;167:5565-5573.
-
(2001)
J Immunol
, vol.167
, pp. 5565-5573
-
-
Suresh, M.1
Whitmire, J.K.2
Harrington, L.E.3
-
14
-
-
0034642499
-
Negative regulation of lymphocyte activation and autoimmunity by the molecular adaptor CbI-b
-
Bachmaier K, Krawczyk C, Kozieradzki I, et al. Negative regulation of lymphocyte activation and autoimmunity by the molecular adaptor CbI-b. Nature. 2000;403:211-216.
-
(2000)
Nature
, vol.403
, pp. 211-216
-
-
Bachmaier, K.1
Krawczyk, C.2
Kozieradzki, I.3
-
15
-
-
0034642534
-
Cbl-b regulates the CD28 dependence of T-cell activation
-
Chiang YJ, Kole HK, Brown K, et al. Cbl-b regulates the CD28 dependence of T-cell activation. Nature. 2000;403:216-220.
-
(2000)
Nature
, vol.403
, pp. 216-220
-
-
Chiang, Y.J.1
Kole, H.K.2
Brown, K.3
-
16
-
-
0036721780
-
Cutting edge: Regulation of T cell activation threshold by CD28 costimulation through targeting Cbl-b for ubiquiti- nation
-
Zhang J, Bardos T, Li D, et al. Cutting edge: regulation of T cell activation threshold by CD28 costimulation through targeting Cbl-b for ubiquiti- nation. J Immunol. 2002;169:2236-2240.
-
(2002)
J Immunol
, vol.169
, pp. 2236-2240
-
-
Zhang, J.1
Bardos, T.2
Li, D.3
-
17
-
-
12444330288
-
Differential control of CD28-regulated in vivo immunity by the E3 ligase Cbl-b
-
Krawczyk CM, Jones RG, Atfield A, et al. Differential control of CD28-regulated in vivo immunity by the E3 ligase Cbl-b. J Immunol. 2005;174:1472-1478.
-
(2005)
J Immunol
, vol.174
, pp. 1472-1478
-
-
Krawczyk, C.M.1
Jones, R.G.2
Atfield, A.3
-
18
-
-
0035555195
-
Proteolysis-independent regulation of PI3K by Cbl-b-mediated ubiquitination in T cells
-
Fang D, Liu YC. Proteolysis-independent regulation of PI3K by Cbl-b-mediated ubiquitination in T cells. Nat Immunol. 2001;2:870-875.
-
(2001)
Nat Immunol
, vol.2
, pp. 870-875
-
-
Fang, D.1
Liu, Y.C.2
-
19
-
-
0035895959
-
-
Fang D, Wang HY, Fang N, Altman Y, Elly C, Liu YC. Cbl-b, a RING-type E3 ubiquitin ligase, targets phosphatidylinositol 3-kinase for ubiquitina- tion in T cells. J Biol Chem. 2001;276:4872-4878.
-
Fang D, Wang HY, Fang N, Altman Y, Elly C, Liu YC. Cbl-b, a RING-type E3 ubiquitin ligase, targets phosphatidylinositol 3-kinase for ubiquitina- tion in T cells. J Biol Chem. 2001;276:4872-4878.
-
-
-
-
20
-
-
0033680925
-
Cbl-b is a negative regulator of receptor clustering and raft aggregation in Tcells
-
Krawczyk C, Bachmaier K, Sasaki T, et al. Cbl-b is a negative regulator of receptor clustering and raft aggregation in Tcells. Immunity. 2000;13:463-473.
-
(2000)
Immunity
, vol.13
, pp. 463-473
-
-
Krawczyk, C.1
Bachmaier, K.2
Sasaki, T.3
-
21
-
-
0032438114
-
Altered thymic positive selection and intracellular signals in Cbl-deficient mice
-
NaramuraM, Kole HK, Hu RJ, Gu H. Altered thymic positive selection and intracellular signals in Cbl-deficient mice. Proc Natl Acad Sci USA.1998;95:15547-15552.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 15547-15552
-
-
Naramura, M.1
Kole, H.K.2
Hu, R.J.3
Gu, H.4
-
22
-
-
0031858649
-
-
Murphy MA, Schnall RG, Venter DJ, et al. Tissue hyperplas a and enhanced T-cell s gnall ng v a ZAP-70 in c-CbI-deficient mice. MoI Cell Biol. 1998;18:4872-4882.
-
Murphy MA, Schnall RG, Venter DJ, et al. Tissue hyperplas a and enhanced T-cell s gnall ng v a ZAP-70 in c-CbI-deficient mice. MoI Cell Biol. 1998;18:4872-4882.
-
-
-
-
23
-
-
0033536637
-
The TyrK negative regulator c-Cbl as a RING-type, E2-dependent ubiquitin- protein ligase
-
Joazeiro CA, Wing SS, Huang H, Leverson JD, Hunter T, Liu YC. The TyrK negative regulator c-Cbl as a RING-type, E2-dependent ubiquitin- protein ligase. Science. 1999;286:309-312.
-
(1999)
Science
, vol.286
, pp. 309-312
-
-
Joazeiro, C.A.1
Wing, S.S.2
Huang, H.3
Leverson, J.D.4
Hunter, T.5
Liu, Y.C.6
-
24
-
-
0033564933
-
Perturbed regulation of ZAP-70 and sustained tyrosine phosphorylation of LAT and SLP-76 in c-Cbl- deficient thymocytes
-
Thien CB, Bowtell DD, Langdon WY. Perturbed regulation of ZAP-70 and sustained tyrosine phosphorylation of LAT and SLP-76 in c-Cbl- deficient thymocytes. J Immunol. 1999;162:7133-7139.
-
(1999)
J Immunol
, vol.162
, pp. 7133-7139
-
-
Thien, C.B.1
Bowtell, D.D.2
Langdon, W.Y.3
-
25
-
-
38849157031
-
Cbl-b regulates antigen-induced TCR down-regulation and IFN-gamma production by effector CD8 Tcells without affecting functional avidity
-
Shamim M, Nanjappa SG, Singh A, et al. Cbl-b regulates antigen-induced TCR down-regulation and IFN-gamma production by effector CD8 Tcells without affecting functional avidity. J Immunol. 2007;179:7233-7243.
-
(2007)
J Immunol
, vol.179
, pp. 7233-7243
-
-
Shamim, M.1
Nanjappa, S.G.2
Singh, A.3
-
26
-
-
27744485874
-
Loss of c-Cbl RING finger function results in high-intensity TCR signaling and thymic deletion
-
Thien CB, Blystad FD, Zhan Y, et al. Loss of c-Cbl RING finger function results in high-intensity TCR signaling and thymic deletion. EMBO J. 2005;24:3807-3819.
-
(2005)
EMBO J
, vol.24
, pp. 3807-3819
-
-
Thien, C.B.1
Blystad, F.D.2
Zhan, Y.3
-
27
-
-
0036911112
-
c-Cbl and Cbl-b regulate Tcell responsiveness by promoting ligand-induced TCR down-modulation
-
Naramura M, Jang IK, Kole H, Huang F, Haines D, Gu H. c-Cbl and Cbl-b regulate Tcell responsiveness by promoting ligand-induced TCR down-modulation. Nat Immunol. 2002;12:1192-1199.
-
(2002)
Nat Immunol
, vol.12
, pp. 1192-1199
-
-
Naramura, M.1
Jang, I.K.2
Kole, H.3
Huang, F.4
Haines, D.5
Gu, H.6
-
28
-
-
1342292522
-
Phosphoinositide 3-kinase: Diverse roles in immune cell activation
-
Deane JA, Fruman DA. Phosphoinositide 3-kinase: diverse roles in immune cell activation. Annu Rev Immunol. 2004;22:563-598.
-
(2004)
Annu Rev Immunol
, vol.22
, pp. 563-598
-
-
Deane, J.A.1
Fruman, D.A.2
-
29
-
-
0033556333
-
B cell development and proliferation in absence of phosphoinositide 3-kinase p85alpha
-
Fruman DA, Snapper SB, Yballe CM, et al. B cell development and proliferation in absence of phosphoinositide 3-kinase p85alpha. Science. 1999;283:393-397.
-
(1999)
Science
, vol.283
, pp. 393-397
-
-
Fruman, D.A.1
Snapper, S.B.2
Yballe, C.M.3
-
30
-
-
0034107671
-
Increased phosphoinositide 3-kinase activityin- duces a lymphoproliferative disorder and contributes to tumor generation in vivo
-
Borlado LR, Redondo C, Alvarez B, et al. Increased phosphoinositide 3-kinase activityin- duces a lymphoproliferative disorder and contributes to tumor generation in vivo. FASEB J. 2000;14:895-903.
-
(2000)
FASEB J
, vol.14
, pp. 895-903
-
-
Borlado, L.R.1
Redondo, C.2
Alvarez, B.3
-
31
-
-
0034635264
-
Function of PI3Kgamma in thymocyte development, Tcell activation, and neutrophil migration
-
Sasaki T, Irie-Sasaki J, Jones RG, et al. Function of PI3Kgamma in thymocyte development, Tcell activation, and neutrophil migration. Science. 2000;287:1040-1046.
-
(2000)
Science
, vol.287
, pp. 1040-1046
-
-
Sasaki, T.1
Irie-Sasaki, J.2
Jones, R.G.3
-
32
-
-
0037047590
-
Impaired B and TCR signaling in p110delta PI 3-kinase mutant mice
-
Okkenhaug K, Bilancio A, Farjot G, et al. Impaired B and TCR signaling in p110delta PI 3-kinase mutant mice. Science. 2002;297:1031-1034.
-
(2002)
Science
, vol.297
, pp. 1031-1034
-
-
Okkenhaug, K.1
Bilancio, A.2
Farjot, G.3
-
33
-
-
2442719040
-
Enhanced Tcell proliferation in mice lacking the p85beta subunit of phosphoino- sitide 3-kinase
-
Deane JA, Trifilo MJ, Yballe CM, Choi S, Lane TE, Fruman DA. Enhanced Tcell proliferation in mice lacking the p85beta subunit of phosphoino- sitide 3-kinase. J Immunol. 2004;172:6615-6625.
-
(2004)
J Immunol
, vol.172
, pp. 6615-6625
-
-
Deane, J.A.1
Trifilo, M.J.2
Yballe, C.M.3
Choi, S.4
Lane, T.E.5
Fruman, D.A.6
-
34
-
-
24744449495
-
PI3Kγ inhibition blocks glomerulonephritis and extends lifespan in a murine systemic lupus model
-
Barber DF, Bartolomé A, Hernández C, et al. PI3Kγ inhibition blocks glomerulonephritis and extends lifespan in a murine systemic lupus model. Nat Med. 2005;11:933-935.
-
(2005)
Nat Med
, vol.11
, pp. 933-935
-
-
Barber, D.F.1
Bartolomé, A.2
Hernández, C.3
-
35
-
-
36549009460
-
Phospho- inositide 3-kinase gamma participates in T cell receptor-induced T cell activation
-
Alcázar I, Marqués M, Kumar A, et al. Phospho- inositide 3-kinase gamma participates in T cell receptor-induced T cell activation. J Exp Med. 2007;204:2977-2987.
-
(2007)
J Exp Med
, vol.204
, pp. 2977-2987
-
-
Alcázar, I.1
Marqués, M.2
Kumar, A.3
-
36
-
-
0028118512
-
Stimulation of CD28 triggers an association between CD28 and phosphatidylinositol 3-kinase in Jurkat Tcells
-
Truitt KE, Hicks CM, Imboden JB. Stimulation of CD28 triggers an association between CD28 and phosphatidylinositol 3-kinase in Jurkat Tcells. J Exp Med. 1994;179:1071-1076.
-
(1994)
J Exp Med
, vol.179
, pp. 1071-1076
-
-
Truitt, K.E.1
Hicks, C.M.2
Imboden, J.B.3
-
37
-
-
0028221022
-
T-cell antigen CD28 interacts with the lipid kinase phosphatidyl- inositol 3-kinase by a cytoplasmic Tyr(P)-Met- Xaa-Met motif
-
Prasad KV, Cai YC, Raab M, et al. T-cell antigen CD28 interacts with the lipid kinase phosphatidyl- inositol 3-kinase by a cytoplasmic Tyr(P)-Met- Xaa-Met motif. Proc Natl Acad Sci USA. 1994; 91:2834-2838.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 2834-2838
-
-
Prasad, K.V.1
Cai, Y.C.2
Raab, M.3
-
38
-
-
0028211126
-
The cytoplasmic domain of CD28 is both necessary and sufficient for costimulation of interleukin-2 secretion and association with PI3K
-
Stein PH, Fraser JD, Weiss A. The cytoplasmic domain of CD28 is both necessary and sufficient for costimulation of interleukin-2 secretion and association with PI3K. Mol Cell Biol. 1994;14:3392-3402.
-
(1994)
Mol Cell Biol
, vol.14
, pp. 3392-3402
-
-
Stein, P.H.1
Fraser, J.D.2
Weiss, A.3
-
39
-
-
0028182749
-
Binding of phosphatidylinositol- 3-OH kinase to CD28 is required for T-cell signalling
-
Pages F, Ragueneau M, Rottapel R, et al. Binding of phosphatidylinositol- 3-OH kinase to CD28 is required for T-cell signalling. Nature. 1994;369:327-329.
-
(1994)
Nature
, vol.369
, pp. 327-329
-
-
Pages, F.1
Ragueneau, M.2
Rottapel, R.3
-
40
-
-
0029931976
-
Two distinct intracytoplasmic regions of the T-cell adhesion molecule CD28 participate in phosphatidyl- inositol 3-kinase association
-
Pagès F, Ragueneau M, Klasen S, et al. Two distinct intracytoplasmic regions of the T-cell adhesion molecule CD28 participate in phosphatidyl- inositol 3-kinase association. J Biol Chem. 1996;271:9403-9409.
-
(1996)
J Biol Chem
, vol.271
, pp. 9403-9409
-
-
Pagès, F.1
Ragueneau, M.2
Klasen, S.3
-
41
-
-
0027711831
-
Positive and negative selection in transgenic mice expressing a T-cell receptor specific for influenza nucleopro- tein and endogenous superantigen
-
Mamalaki C, Elliott J, Norton T, et al. Positive and negative selection in transgenic mice expressing a T-cell receptor specific for influenza nucleopro- tein and endogenous superantigen. Dev Immunol. 1993;3:159-174.
-
(1993)
Dev Immunol
, vol.3
, pp. 159-174
-
-
Mamalaki, C.1
Elliott, J.2
Norton, T.3
-
42
-
-
0032472913
-
Identification and characterization of a new onco- gene derived from the regulatory subunit of phos- phoinositide 3-kinase
-
Jimenez C, Jones DR, Rodríguez-Viciana P, et al. Identification and characterization of a new onco- gene derived from the regulatory subunit of phos- phoinositide 3-kinase. EMBO J. 1998;17:743-753.
-
(1998)
EMBO J
, vol.17
, pp. 743-753
-
-
Jimenez, C.1
Jones, D.R.2
Rodríguez-Viciana, P.3
-
43
-
-
34249931118
-
Class IAphosphoinositide 3-kinases are obligate p85-p110 heterodimers
-
Geering B, Cutillas PR, Nock G, Gharbi SI, Vanhaesebroeck B. Class IAphosphoinositide 3-kinases are obligate p85-p110 heterodimers. Proc Natl Acad Sci USA. 2007;104:7809-7814.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 7809-7814
-
-
Geering, B.1
Cutillas, P.R.2
Nock, G.3
Gharbi, S.I.4
Vanhaesebroeck, B.5
-
44
-
-
0029117423
-
Specific association of the beta isoform of the p85 subunit of phosphatidylinositol-3 kinase with the proto- oncogenec-cbl
-
Hartley D, Meisner H, Corvera S. Specific association of the beta isoform of the p85 subunit of phosphatidylinositol-3 kinase with the proto- oncogenec-cbl. J Biol Chem. 1995;270:18260-18263.
-
(1995)
J Biol Chem
, vol.270
, pp. 18260-18263
-
-
Hartley, D.1
Meisner, H.2
Corvera, S.3
-
45
-
-
4143137360
-
Essential role of the E3 ubiquitin ligase Cbl-b in T cell an- ergy induction
-
Jeon MS, Atfield A, Venuprasad K, et al. Essential role of the E3 ubiquitin ligase Cbl-b in T cell an- ergy induction. Immunity. 2004;21:167-177.
-
(2004)
Immunity
, vol.21
, pp. 167-177
-
-
Jeon, M.S.1
Atfield, A.2
Venuprasad, K.3
-
46
-
-
4644285392
-
E3 ubiquitin ligases as T cell anergy factors
-
Mueller DL. E3 ubiquitin ligases as T cell anergy factors. Nat Immunol. 2004;5:883-890.
-
(2004)
Nat Immunol
, vol.5
, pp. 883-890
-
-
Mueller, D.L.1
-
47
-
-
12144290293
-
Calcineurin imposes T cell unresponsiveness through targeted proteolysis of signaling proteins
-
Heissmeyer V, Macián F, Im SH, et al. Calcineurin imposes T cell unresponsiveness through targeted proteolysis of signaling proteins. Nat Immunol. 2004;5:255-265.
-
(2004)
Nat Immunol
, vol.5
, pp. 255-265
-
-
Heissmeyer, V.1
Macián, F.2
Im, S.H.3
-
48
-
-
0037124330
-
Constitutive endocytosis and degradation of the pre- T cell receptor
-
Panigada M, Porcellini S, Barbier E, et al. Constitutive endocytosis and degradation of the pre- T cell receptor. J Exp Med. 2002;195:1585-1597.
-
(2002)
J Exp Med
, vol.195
, pp. 1585-1597
-
-
Panigada, M.1
Porcellini, S.2
Barbier, E.3
-
49
-
-
0242290342
-
WW domain HECT E3s target Cbl RING finger E3s for proteasomal degradation
-
Magnifico A, Ettenberg S, Yang C, et al. WW domain HECT E3s target Cbl RING finger E3s for proteasomal degradation. J Biol Chem. 2003;278:43169-43177.
-
(2003)
J Biol Chem
, vol.278
, pp. 43169-43177
-
-
Magnifico, A.1
Ettenberg, S.2
Yang, C.3
-
50
-
-
0032472840
-
Endogenous interleukin 4 is required for development of protective CD4+ T helper type 1 cell responses to Candida albicans
-
Mencacci A, Del Sero G, Cenci E, et al. Endogenous interleukin 4 is required for development of protective CD4+ T helper type 1 cell responses to Candida albicans. J Exp Med. 1998;187:307-317.
-
(1998)
J Exp Med
, vol.187
, pp. 307-317
-
-
Mencacci, A.1
Del Sero, G.2
Cenci, E.3
-
51
-
-
0029849196
-
CD4+ T-helper-cell responses in mice with low- level Candida albicans infection
-
Mencacci A, Spaccapelo R, Del Sero G, et al. CD4+ T-helper-cell responses in mice with low- level Candida albicans infection. Infect Immun. 1996;64:4907-4914.
-
(1996)
Infect Immun
, vol.64
, pp. 4907-4914
-
-
Mencacci, A.1
Spaccapelo, R.2
Del Sero, G.3
-
52
-
-
0029975023
-
Blocked signal transduction to the ERK and JNK protein kinases in anergic CD4+ T cells
-
Li W, Whaley CD, Mondino A, Mueller DL. Blocked signal transduction to the ERK and JNK protein kinases in anergic CD4+ T cells. Science. 1996;271:1272-1276.
-
(1996)
Science
, vol.271
, pp. 1272-1276
-
-
Li, W.1
Whaley, C.D.2
Mondino, A.3
Mueller, D.L.4
-
53
-
-
0035319244
-
Apoint mutation in CD28 distinguishes proliferative signals from survival signals
-
Okkenhaug K, Wu L, Garza KM, et al. Apoint mutation in CD28 distinguishes proliferative signals from survival signals. Nat Immunol. 2001;2:325-332.
-
(2001)
Nat Immunol
, vol.2
, pp. 325-332
-
-
Okkenhaug, K.1
Wu, L.2
Garza, K.M.3
-
54
-
-
38949150779
-
CD28 provides T-cell costimulation and enhances PI3K activity at the immune synapse independently of its capacity to interact with the p85/p110 het- erodimer
-
Garcon F, Patton DT, Emery JL, et al. CD28 provides T-cell costimulation and enhances PI3K activity at the immune synapse independently of its capacity to interact with the p85/p110 het- erodimer. Blood. 2008;111:1464-1471.
-
(2008)
Blood
, vol.111
, pp. 1464-1471
-
-
Garcon, F.1
Patton, D.T.2
Emery, J.L.3
-
55
-
-
0027980250
-
T cell receptor-associated alpha-phosphatidylinositol 3-kinase becomes activated by T cell receptor cross-linking and requires pp56lck
-
Carrera AC, Rodriguez-Borlado L, Martinez- Alonso C, Merida I. T cell receptor-associated alpha-phosphatidylinositol 3-kinase becomes activated by T cell receptor cross-linking and requires pp56lck. J Biol Chem. 1994;269:19435-19440.
-
(1994)
J Biol Chem
, vol.269
, pp. 19435-19440
-
-
Carrera, A.C.1
Rodriguez-Borlado, L.2
Martinez- Alonso, C.3
Merida, I.4
-
56
-
-
0033997322
-
The role of membrane- associated adaptors in T cell receptor signalling
-
Zhang W, Samelson LE. The role of membrane- associated adaptors in T cell receptor signalling. Semin Immunol. 2000;12:35-41.
-
(2000)
Semin Immunol
, vol.12
, pp. 35-41
-
-
Zhang, W.1
Samelson, L.E.2
-
57
-
-
33750963809
-
Sjogren's syndrome-like disease in mice with T cells lacking class 1Aphosphoinositide-3-kinase
-
Oak JS, Deane JA, Kharas MG, et al. Sjogren's syndrome-like disease in mice with T cells lacking class 1Aphosphoinositide-3-kinase. Proc Natl Acad Sci USA. 2006;103:16882-16887.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 16882-16887
-
-
Oak, J.S.1
Deane, J.A.2
Kharas, M.G.3
-
58
-
-
15044358690
-
Role of phosphoinositide 3-kinase regulatory iso- forms in development and actin rearrangement
-
Brachmann SM, Yballe CM, Innocenti M, et al. Role of phosphoinositide 3-kinase regulatory iso- forms in development and actin rearrangement. Mol Cell Biol. 2005;25:2593-2606.
-
(2005)
Mol Cell Biol
, vol.25
, pp. 2593-2606
-
-
Brachmann, S.M.1
Yballe, C.M.2
Innocenti, M.3
-
59
-
-
0031887249
-
Regulation of the p85/p110 phos- phatidylinositol 3'-kinase: Stabilization and inhibition of the p110alpha catalytic subunit by the p85 regulatory subunit
-
Yu J, Zhang Y, McIlroy J, Rordorf-Nikolic T, Orr GA, Backer JM. Regulation of the p85/p110 phos- phatidylinositol 3'-kinase: stabilization and inhibition of the p110alpha catalytic subunit by the p85 regulatory subunit. Mol Cell Biol. 1998;18:1379-1387.
-
(1998)
Mol Cell Biol
, vol.18
, pp. 1379-1387
-
-
Yu, J.1
Zhang, Y.2
McIlroy, J.3
Rordorf-Nikolic, T.4
Orr, G.A.5
Backer, J.M.6
-
60
-
-
33750807672
-
Cutting edge: The phosphoinositide 3-kinase p110 delta is critical forthe function of CD4+CD25+Foxp3 + regulatory T cells
-
Patton DT, Garden OA, Pearce WP, et al. Cutting edge: the phosphoinositide 3-kinase p110 delta is critical forthe function of CD4+CD25+Foxp3 + regulatory T cells. J Immunol. 2006;177:6598-6602.
-
(2006)
J Immunol
, vol.177
, pp. 6598-6602
-
-
Patton, D.T.1
Garden, O.A.2
Pearce, W.P.3
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