Ribozyme rescue of photoreceptor cells in a transgenic rat model of autosomal dominant retinitis pigmentosa

Nature Medicine

Volumn 4, Issue 8, 1998, Pages 967-971

  Lewin, Alfred S ^a   Drenser, Kimberly A ^a   Hauswirth, William W ^a   Nishikawa, Shimpei ^b   Yasumura, Douglas ^b   Flannery, John G ^c   Lavail, Matthew M ^b  

^a UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

RIBOZYME;

ADENO ASSOCIATED VIRUS; AMINO ACID SUBSTITUTION; ANIMAL MODEL; ARTICLE; AUTOSOMAL DOMINANT DISORDER; CATALYSIS; ELECTRORETINOGRAM; EXPRESSION VECTOR; GENETIC TRANSDUCTION; NERVE CELL DEGENERATION; NONHUMAN; PHOTORECEPTOR CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RETINITIS PIGMENTOSA; RNA CLEAVAGE;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; DEPENDOVIRUS; DISEASE MODELS, ANIMAL; GENE THERAPY; GENES, DOMINANT; HISTIDINE; OPSIN; PHOTORECEPTORS; POINT MUTATION; PROLINE; PROMOTER REGIONS (GENETICS); RATS; RATS, SPRAGUE-DAWLEY; RETINITIS PIGMENTOSA; RHODOPSIN; RNA, CATALYTIC; RODS (RETINA);

ADENO-ASSOCIATED VIRUS; ANIMALIA;

EID: 0031880563     PISSN: 10788956     EISSN: None     Source Type: Journal    
DOI: 10.1038/nm0898-967     Document Type: Article

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