Effects of histamine H 4 receptor ligands in a mouse model of gastric ulceration

Pharmacology

Volumn 89, Issue 5-6, 2012, Pages 287-294

  Adami, Maristella ^a   Pozzoli, Cristina ^a   Menozzi, Alessandro ^a   Bertini, Simone ^a   Passeri, Benedetta ^a   Cantoni, Anna Maria ^a   Smits, Rogier ^b   De Esch, Iwan ^b   Leurs, Rob ^c   Coruzzi, Gabriella ^a  

^a UNIVERSITY OF PARMA   (Italy)

^b Griffin Discoveries BV   (Netherlands)

^c VU UNIVERSITY AMSTERDAM   (Netherlands)

Author keywords

Gastric mucosal damage; Histamine H 4 receptor; JNJ7777120; Mouse strain; VUF10460; VUF8430

Indexed keywords

1 (5 CHLORO 2 INDOLYLCARBONYL) 4 METHYLPIPERAZINE; 2 (2 GUANIDINOETHYL)ISOTHIOUREA; 4 (4 METHYLPIPERAZIN 1 YL) 6 PHENYLPYRIMIDIN 2 AMINE; AGENTS INTERACTING WITH TRANSMITTER, HORMONE OR DRUG RECEPTORS; BETHANECHOL; HISTAMINE H4 RECEPTOR; INDOMETACIN; RANITIDINE; UNCLASSIFIED DRUG; VUF 10460; 1 ((5 CHLORO 1H INDOL 2 YL)CARBONYL) 4 METHYLPIPERAZINE; 1-((5-CHLORO-1H-INDOL-2-YL)CARBONYL)-4-METHYLPIPERAZINE; ANTIHISTAMINIC AGENT; ANTIINFLAMMATORY AGENT; DRUG DERIVATIVE; G PROTEIN COUPLED RECEPTOR; GUANIDINE DERIVATIVE; HISTAMINE AGONIST; HISTAMINE RECEPTOR; HRH4 PROTEIN, MOUSE; INDOLE DERIVATIVE; PIPERAZINE DERIVATIVE; PYRIMIDINE DERIVATIVE; S (2 GUANIDYLETHYL)ISOTHIOUREA; S-(2-GUANIDYLETHYL)ISOTHIOUREA; THIOUREA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG ANTAGONISM; DRUG EFFECT; FEMALE; HISTOPATHOLOGY; MOUSE; MOUSE STRAIN; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; STOMACH FUNDUS; STOMACH LESION; STOMACH PROTECTION; STOMACH ULCER; ULCEROGENESIS; ANIMAL; C57BL MOUSE; CHEMICALLY INDUCED DISORDER; DISEASE MODEL; DRUG POTENTIATION; MALE; METABOLISM; PATHOLOGY; SPECIES DIFFERENCE;

ANIMALS; ANTI-INFLAMMATORY AGENTS; BETHANECHOL; DISEASE MODELS, ANIMAL; GUANIDINES; HISTAMINE AGONISTS; HISTAMINE ANTAGONISTS; INDOLES; INDOMETHACIN; MALE; MICE; MICE, INBRED C57BL; PIPERAZINES; PYRIMIDINES; RECEPTORS, G-PROTEIN-COUPLED; RECEPTORS, HISTAMINE; SPECIES SPECIFICITY; STOMACH ULCER; THIOUREA;

EID: 84860164856     PISSN: 00317012     EISSN: 14230313     Source Type: Journal    
DOI: 10.1159/000337736     Document Type: Article

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