Inhibitory effects of theophylline on the peroxynitrite-augmented release of matrix metalloproteinases by lung fibroblasts

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 302, Issue 8, 2012, Pages

  Sugiura, Hisatoshi ^a   Kawabata, Hiroki ^a   Ichikawa, Tomohiro ^a   Koarai, Akira ^a   Yanagisawa, Satoru ^a   Kikuchi, Takashi ^a   Minakata, Yoshiaki ^a   Matsunaga, Kazuto ^a   Nakanishi, Masanori ^a   Hirano, Tsunahiko ^a   Akamatsu, Keiichiro ^a   Furukawa, Kanako ^a   Ichinose, Masakazu ^a  

^a WAKAYAMA MEDICAL UNIVERSITY   (Japan)

Author keywords

Chronic obstructive pulmonary disease; Fibroblast; Phosphodiesterase inhibitor; Proteinase; Reactive nitrogen species

Indexed keywords

GELATIN; GELATINASE; GELATINASE A; GELATINASE B; HISTONE DEACETYLASE; HISTONE DEACETYLASE 2; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PEROXYNITRITE; THEOPHYLLINE; TRANSFORMING GROWTH FACTOR BETA1;

ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL VIABILITY; CONTROLLED STUDY; CYTOKINE RELEASE; ENZYME INHIBITION; ENZYME RELEASE; HUMAN; HUMAN CELL; LUNG FIBROBLAST; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; ZYMOGRAPHY;

ANTIBODIES, NEUTRALIZING; BRONCHODILATOR AGENTS; CELL LINE; CELLS, CULTURED; FIBROBLASTS; HISTONE DEACETYLASES; HUMANS; LUNG; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; NF-KAPPA B; PEROXYNITROUS ACID; SIGNAL TRANSDUCTION; THEOPHYLLINE; TRANSFORMING GROWTH FACTOR BETA1;

EID: 84859778323     PISSN: 10400605     EISSN: 15221504     Source Type: Journal    
DOI: 10.1152/ajplung.00342.2011     Document Type: Article

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