Human microsomal carbonyl reducing enzymes in the metabolism of xenobiotics: Well-known and promising members of the SDR superfamily

Drug Metabolism Reviews

Volumn 44, Issue 2, 2012, Pages 173-191

  Škarydová, Lucie ^a   Wsól, Vladimír ^a  

^a Charles University in Prague Faculty of Pharmacy   (Czech Republic)

Author keywords

11 HSDs; 17 HSDs; Biotransformation; Carbonyl; RDHs; Reduction; SDR; Xenobiotics

Indexed keywords

11BETA HYDROXYSTEROID DEHYDROGENASE 1; 11BETA HYDROXYSTEROID DEHYDROGENASE 2; 4 QUINONE; 7 OXOCHOLESTEROL; ALDEHYDE; ALDOSTERONE; BENFLURON; CARBONYL REDUCING ENZYME; CORTICOSTEROID; CORTISONE; CYTOCHROME P450; GLUCOCORTICOID RECEPTOR; HYDROCORTISONE; HYDROQUINONE; HYDROXYSTEROID DEHYDROGENASE; KETOPROFEN; MEDIUM CHAIN DEHYDROGENASE REDUCTASE; METYRAPONE; MICROSOME ENZYME; MINERALOCORTICOID RECEPTOR; PREDNISOLONE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE (PHOSPHATE) DEHYDROGENASE (QUINONE); REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; RETINOL DEHYDROGENASE; RETINOL DEHYDROGENASE 12; SEMIQUINONE; SHORT CHAIN DEHYDROGENASE REDUCTASE; TRIADIMEFON; UNCLASSIFIED DRUG; UNINDEXED DRUG; XENOBIOTIC AGENT;

BIOTRANSFORMATION; CARCINOGENIC ACTIVITY; CATALYSIS; CYTOSOL; DETOXIFICATION; DRUG METABOLISM; ENDOPLASMIC RETICULUM; ENZYME ACTIVITY; HAMSTER; HUMAN; LIPID PEROXIDATION; MICROSOME; NONHUMAN; OXIDATIVE STRESS; REVIEW; XENOBIOTIC METABOLISM;

11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1; 17-HYDROXYSTEROID DEHYDROGENASES; ALCOHOL OXIDOREDUCTASES; ANIMALS; BIOTRANSFORMATION; CARBOXYLIC ACIDS; CATALYSIS; ENDOPLASMIC RETICULUM; HUMANS; MICROSOMES; MOLECULAR STRUCTURE; OXIDATION-REDUCTION; SUBSTRATE SPECIFICITY; XENOBIOTICS;

EID: 84859758143     PISSN: 03602532     EISSN: 10979883     Source Type: Journal    
DOI: 10.3109/03602532.2011.638304     Document Type: Review

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