Isolation and characterization of novel human short-chain dehydrogenase/reductase SCDR10B which is highly expressed in the brain and acts as hydroxysteroid dehydrogenase

Acta Biochimica Polonica

Volumn 56, Issue 2, 2009, Pages 279-289

  Huang, Chaoqun ^a,b   Wan, Bo ^a   Gao, Bo ^c   Hexige, Saiyin ^a   Yu, Long ^a  

^a FUDAN UNIVERSITY   (China)

^b OKLAHOMA STATE UNIVERSITY   (United States)

^c SOOCHOW UNIVERSITY   (China)

Author keywords

Brain; Clone; Expression pattern; Hydroxysteroid dehydrogenase

Indexed keywords

MAMMALIA; RODENTIA;

EID: 68249089502     PISSN: 0001527X     EISSN: 1734154X     Source Type: Journal    
DOI: 10.18388/abp.2009_2460     Document Type: Article

References (35)

1. Arriza JL, Simerly RB, Swanson LW, Evans RM (1988) The neuronal mineralocorticoid receptor as a mediator of glucocorticoid response. Neuron 1: 887-900.
2. Audige A, Dick B, Frey BM, Frey FJ, Corman B, Vogt B (2002) Glucocorticoids and 11β-hydroxysteroid dehy-drogenase type 2 gene expression in the aging kidney. Eur J Clin Invest 32: 411-420.
3. Baker ME (2004) Evolutionary analysis of 11β-hydroxysteroid dehydr-ogenase-type 1, -type 2, -type 3 and 17betahydroxysteroid dehydrogenase-type 2 in fish. FEBS Lett 574: 167-170.
4. Brereton PS, van Driel RR, Suhaimi F, Koyama K, Dilley R, Krozowski Z (2001) Light and electron microscopy localization of the 11β-hydroxysteroid dehydrogenase type I enzyme in the rat. Endocrinology 142: 1644-1651.
5. Bujalska IJ, Walker EA, Hewison M, Stewart PM (2002a) A switch in dehydrogenase to reductase activity of 11β-hydroxysteroid dehydrogenase type 1 upon differentiation of human omental adipose stromal cells. J Clin Endocrinol Metab 87: 1205-1210.
6. Bujalska IJ, Walker EA, Tomlinson JW, Hewison M, Stewart PM (2002b) 11β-hydroxysteroid dehydrogenase type 1 in differentiating omental human preadipocytes: from de-activation to generation of cortisol. Endocr Res 28: 449-461.
7. Cohen PG (2005) Estradiol induced inhibition of 11β-hydroxysteroid dehydrogenase 1: an explanation for the postmenopausal hormone replacement therapy effects. Med Hypotheses 64: 989-991.
8. De Kloet ER, Van Acker SA, Sibug RM, Oitzl MS, Meijer OC, Rahmouni K, de Jong W (2000) Brain mineralocor-ticoid receptors and centrally regulated functions. Kidney Int 57: 1329-1336.
9. Diaz R, Brown RW, Seckl JR (1998) Distinct ontogeny of glucocorticoid and mineralocorticoid receptor and 11β- hydroxysteroid dehydrogenase types I and II mRNAs in the fetal rat brain suggest a complex control of glucocorticoid actions. J Neurosci 18: 2570-2580.
10. Felsenstein J (1985) Confidence limits on phylogenics: an approach using the bootstrap. Evolution 39: 783-791.
11. Filling C, Berndt KD, Benach J, Knapp S, Prozorovski T, Nordling E, Ladenstein R, Jornvall H, Oppermann UC (2002) Critical residues for structure and catalysis in shortchain dehydrogenases/reductases. J Biol Chem 277: 25677-25684.
12. Funder JW (2005) Mineralocorticoid receptors: distribution and activation. Heart Fail Rev 10: 15-22.
13. Henderson BE, Feigelson HS (2000) Hormonal carcinogenesis. Carcinogenesis 21: 427-433.
14. Huang CQ, Zhou JL, Wu SL, Shan YX, Ten SL, Yu L (2004) Cloning and tissue distribution of the human B3GALT7 gene, a member of the β1,3-glycosyltransferase family. Glycoconj J 21: 267-273.
15. Jornvall H, Persson B, Krook M, Atrian S, Gonzalez-Duarte R, Jeffery J, Ghosh D (1995) Short-chain dehydrogenases/reductases (SDR). Biochemistry 34: 6003-6013.
16. Kallberg Y, Oppermann U, Jornvall H, Persson B (2002) Short-chain dehydrogenase/reductase (SDR) relation-ships: a large family with eight clusters common to human, animal, and plant genomes. Protein Sci 11: 636-641.
17. Kataoka S, Kudo A, Hirano H, Kawakami H, Kawano T, Higashihara E, Tanaka H, Delarue F, Sraer JD, Mune T, Krozowski ZS, Yan K (2002) 11β-hydroxysteroid dehydrogenase type 2 is expressed in the human kidney glomerulus. J Clin Endocrinol Metab 87: 877-882.
18. Kotelevtsev Y, Brown RW, Fleming S, Kenyon C, Edwards CR, Seckl JR, Mullins JJ (1999) Hypertension in mice lacking 11β-hydroxysteroid dehydrogenase type 2. J Clin Invest 103: 683-689.
19. Koyama K, Myles K, Smith R, Krozowski Z (2001) Expression of the 11β-hydroxysteroid dehydrogenase type II enzyme in breast tumors and modulation of activity and cell growth in PMC42 cells. J Steroid Biochem Mol Biol 76: 153-159.
20. Krozowski ZS, Stewart PM, Obeyesekere VR, Li K, Ferrari P (1997) Mutations in the 11β-hydroxysteroid dehydro-genase type II enzyme associated with hypertension and possibly stillbirth. Clin Exp Hypertens 19: 519-529.
21. Lin LJ, Tai S, Peng CC, Tzen J (2002) Steroleosin, a sterol-binding dehydrogenase in seed oil bodies. Plant Physiol 128: 1200-1211.
22. Lin-Su K, Zhou P, Arora N, Betensky BP, New MI, Wilson RC (2004) In vitro expression studies of a novel mutation delta299 in a patient affected with apparent mineralocorticoid excess. J Clin Endocrinol Metab 89: 2024-2027.
23. Nigawara T, Iwasaki Y, Asai M, Yoshida M, Kambayashi M, Sashinami H, Hashimoto K, Suda T (2006) Inhibi tion of 11β-hydroxysteroid dehydrogenase eliminates impaired glucocorticoid suppression and induces apoptosis in corticotroph tumor cells. Endocrinology 147: 769-772.
24. Oppermann UC, Filling C, Berndt KD, Persson B, Benach J, Ladenstein R, Jornvall H (1997) Active site directed mutagenesis of 3 beta/17 beta-hydroxysteroid dehydrogenase establishes differential effects on short-chain dehydrogenase/reductase reactions. Biochemistry 36: 34-40.
25. Ozols J (1995) Lumenal orientation and post-translational modifications of the liver microsomal 11β-hydroxyster-oid dehydrogenase. J Biol Chem 270: 10360.
26. Patel PD, Sherman TG, Goldman DJ, Watson SJ (1989) Molecular cloning of a mineralocorticoid (type 1) receptor complementary DNA from rat hippcampus. Mol Cell Endocrinol 3: 1877-1885.
27. Poletto R, Steibel JP, Siegford JM, Zanella AJ (2006) Effects of early weaning and social isolation on the expression of glucocorticoid and mineralocorticoid receptor and 11β-hydroxysteroid dehydrogenase 1 and 2 mRNAs in the frontal cortex and hippocampus of piglets. Brain Res 1067: 36-42.
28. Rabbitt EH, Lavery GG, Walker EA, Cooper MS, Stewart PM, Hewison M (2002) Prereceptor regulation of glucocorticoid action by 11β-hydroxysteroid dehydrogenase: a novel determinant of cell proliferation. Faseb J 16: 36-44.
29. Rabbitt EH, Gittoes NJ, Stewart PM, Hewison M (2003) 11β-hydroxysteroid dehydrogenases, cell proliferation and malignancy. J Steroid Biochem Mol Biol 85: 415-421.
30. Ricketts ML, Verhaeg JM, Bujalska I, Howie AJ, Rainey WE, Stewart PM (1998) Immunohistochemical localization of type 1 11β-hydroxysteroid dehydrogenase in human tissues. J Clin Endocrinol Metab 83: 1325-1335.
31. Stewart PM, Boulton A, Kumar S, Clark PM, Shackleton CH (1999) Cortisol metabolism in human obesity: impaired cortisone→cortisol conversion in subjects with central adiposity. J Clin Endocrinol Metab 84: 1022-1027.
32. Tomlinson JW, Bujalska I, Stewart PM, Cooper MS (2000) The role of 11β-hydroxysteroid dehydrogenase in central obesity and osteoporosis. Endocr Res 26: 711-722.
33. Watzka M, Beyenburg S, Blumcke I, Elger CE, Bidlingmaier F, Stoffel-Wagner B (2000) Expression of minera-locorticoid and glucocorticoid receptor mRNA in the human hippocampus. Neurosci Lett 290: 121-124.
34. Wolf G (2002) Glucocorticoids in adipocytes stimulate visceral obesity. Nutr Rev 60: 148-151.
35. Zbankova S, Bryndova J, Kment M, Pacha J (2004) Expression of 11β-hydroxysteroid dehydrogenase types 1 and 2 in colorectal cancer. Cancer Lett 210: 95-100.