A Conserved Role for Phosphatidylinositol 3-Kinase but Not Akt Signaling in Mitochondrial Adaptations that Accompany Physiological Cardiac Hypertrophy

Cell Metabolism

Volumn 6, Issue 4, 2007, Pages 294-306

  O'Neill, Brian T ^a   Kim, Jaetaek ^a   Wende, Adam R ^a   Theobald, Heather A ^a   Tuinei, Joseph ^a   Buchanan, Jonathan ^a   Guo, Aili ^a   Zaha, Vlad G ^a   Davis, Don K ^a   Schell, John C ^a   Boudina, Sihem ^a   Wayment, Benjamin ^a   Litwin, Sheldon E ^a   Shioi, Tetsuo ^b   Izumo, Seigo ^c   Birnbaum, Morris J ^d   Abel, E Dale ^a  

^a UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^b KITASATO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH   (United States)

^d UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

HUMDISEASE; SIGNALING

Indexed keywords

PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL GROWTH; CONTROLLED STUDY; ENZYME ACTIVATION; EXERCISE; FATTY ACID METABOLISM; FATTY ACID OXIDATION; HEART HYPERTROPHY; HEART MITOCHONDRION; METABOLIC REGULATION; MORPHOLOGICAL ADAPTATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ADAPTATION, PHYSIOLOGICAL; ANIMALS; CARDIOMEGALY; FATTY ACIDS; GENE EXPRESSION REGULATION; ISOENZYMES; MICE; MICE, MUTANT STRAINS; MITOCHONDRIA; MYOCYTES, CARDIAC; OXIDATION-REDUCTION; PHYSICAL CONDITIONING, ANIMAL; PROTEIN ISOFORMS; PROTEIN KINASE C; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION;

EID: 34548850040     PISSN: 15504131     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cmet.2007.09.001     Document Type: Article

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