Replacing conventional carbon nucleophiles with electrophiles: Nickel-catalyzed reductive alkylation of aryl bromides and chlorides

Journal of the American Chemical Society

Volumn 134, Issue 14, 2012, Pages 6146-6159

  Everson, Daniel A ^a   Jones, Brittany A ^a,b   Weix, Daniel J ^a  

^a UNIVERSITY OF ROCHESTER   (United States)

^b Materia Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALKYL BROMIDES; ARYL BROMIDES; ARYL CHLORIDE; ARYL HALIDES; BROMOALKANES; CARBON NUCLEOPHILES; CHEMO-SELECTIVITY; CHEMOSELECTIVE; CROSS COUPLING REACTIONS; ELECTROPHILES; ELECTROPHILIC CARBON; GENERAL METHOD; HIGH YIELD; INVERSE DEPENDENCE; LINEAR CORRELATION; NUCLEOPHILIC CARBON; OPTIMIZED CONDITIONS; ORGANIC HALIDES; ORGANIC REDUCTANTS; ORGANOBORON; ORGANOSILICONES; ORGANOTINS; ORGANOZINC REAGENTS; OXIDATIVE ADDITIONS; POSITIVE DEPENDENCE; RATE OF REACTION; REDUCTIVE ALKYLATION; RELATIVE RATES; SELECTIVE COUPLING; SUZUKI-MIYAURA; VINYL BROMIDES;

BROMINE COMPOUNDS; CHLORINE COMPOUNDS; IONIC LIQUIDS; METAL HALIDES; ORGANOMETALLICS; SULFUR DIOXIDE;

CARBON;

BROMIDE; CARBON; CHLORIDE; ELECTROPHILE; NICKEL; NUCLEOPHILE; ORGANOBORON DERIVATIVE; ORGANOHALOGEN DERIVATIVE; ORGANOSILICON DERIVATIVE; ORGANOTIN COMPOUND; SODIUM IODIDE;

ALKYLATION; ARTICLE; CATALYST; CHEMICAL BOND; CONCENTRATION (PARAMETERS); CROSS COUPLING REACTION; HYDROLYSIS;

ALKANES; BINDING, COMPETITIVE; BROMIDES; CATALYSIS; CHEMISTRY; CHLORIDES; CROSS-LINKING REAGENTS; KINETICS; LIGANDS; METALS; MODELS, CHEMICAL; MODELS, STATISTICAL; MOLECULAR STRUCTURE; NICKEL;

EID: 84859607989     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja301769r     Document Type: Article

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